Clinical trials: sponsored by Aalborg University Hospital
Brain Tumor, Pediatric, Cancer-related Fatigue
Methylphenidate in Pediatric Brain Tumor Survivors With Cancer-related Fatigue
Cancer-related fatigue is a common and debilitating late effect in pediatric brain tumor survivors. Currently, evidence-based recommendations to ameliorate this condition are lacking.
- Conditions
- Brain Tumor, Pediatric, Cancer-related Fatigue, Methylphenidate
- Trial name
- EMBRAIN (NCT06905587)
- Testing
- Methylphenidate (MPH)
- Where
- 4 sites in Denmark
- Volunteers
- 50 people
- Sponsor
- Odense University Hospital
Herpes Simplex 2, Meningitis, Viral
Aciclovir Versus Placebo for HSV-2 Meningitis
To determine whether active treatment with (val)acyclovir is superior for treatment of viral meningitis compared with placebo assessed by numbers meeting a primary, objective endpoint at 7 days after randomisation
- Trial name
- AMEN (NCT05452928)
- Testing
- Acyclovir 50 MG/ML
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Jacob Bodilsen
Preterm, Father-Child Relations
The SUPPORTED Study - First-time Fathers of Preterm Infants.
The purpose is to support first-time fathers of premature infants in early parenthood by promoting early paternal-infant relationships.
- Trial name
- NCT06116747
- Testing
- Intervention
- Where
- Denmark
- Volunteers
- 915 people, healthy volunteers welcome
- Sponsor
- Hvidovre University Hospital
Metastatic Castration Resistant Prostate Cancer (mCRPC)
Cannabidiol for Pain Relief of Patients With End-stage mCRPC
The goal of this clinical trial is to evaluate the effects of cannabidiol in patients with end-stage metastatic castration-resistant prostate cancer (mCRPC).
- Trial name
- ProCan (NCT07549256)
- Testing
- Cannabidiol
- Where
- Denmark
- Volunteers
- 58 people
- Sponsor
- Regionshospital Nordjylland
Congenital Hyperinsulinism (CHI)
Umbilical Cord Glucose
Congenital hyperinsulinism (HI) causes persistent neonatal hypoglycemia that, if untreated, can lead to neurodevelopmental impairments (NDI) such as cognitive delays, cerebral palsy, epilepsy, and blindness.
- Trial name
- Save The Brain (NCT07795047)
- Testing
- For the screening, the interventions will be glucose measurements (and possibly G-BOBH), while follow-up assessments will include Bayley testing, EEG, and MRI.
- Volunteers
- 50 people
- Sponsor
- Odense University Hospital
Infratentorial Neoplasms, Mutism
Cerebellar Mutism Syndrome Study
The purpose of this study is to determine why up to 25% of the pediatric patients who have surgery for a tumor in the posterior fossa develops the Cerebellar Mutism Syndrome (CMS).
- Trial name
- NCT02300766
- Where
- 32 sites in Austria, Belgium and 12 more
- Volunteers
- 2,000 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Infertility
Food Intake Among Women and Men in Fertility Treatment
Worldwide infertility is highly prevalent and lifestyle factors, such as food intake, could have an essential role in the success of a fertility treatment.
- Trial name
- Food&Fertility (NCT05454046)
- Testing
- Food intake among women and men in fertility treatment
- Where
- 8 sites in Denmark
- Volunteers
- 4,000 people
- Sponsor
- Aalborg University Hospital
Hyperprolactinemia, Puberty Disorders
PROSA: Prolactin, Sex Hormones, Growth and Metabolic Biomarkers in Children and Adolescents on Antipsychotics
The objectives of this study are: 1. To determine the prevalence and degree of hyperprolactinemia in children and adolescents aged 7-18 years receiving antipsychotic medications 2.
- Conditions
- Hyperprolactinemia, Puberty Disorders, Metabolic Syndrome, Growth Disorders
- Trial name
- PROSA (NCT05033119)
- Where
- 3 sites in Denmark
- Volunteers
- 90 people
- Sponsor
- Ulla Schierup Nielsen
Mental Health Help-Seeking, Mental Health Difficulties
Changes in Children and Young People's Well-being and Parental Stress While Seeking Help at CAMHS in Denmark. How Does Waiting Affect CYP and Their Parents Before, During and After CAMHS Assessments.
Questionnaire-based longitudinal cohort study. Families on the waiting list for an assessment with Child and Adolescent Mental Health Services (CAMHS) are invited to complete questionnaires including the Parental Stress Scale…
- Conditions
- Mental Health Help-Seeking, Mental Health Difficulties, Help-Seeking Behavior, Waiting Times, Patient Pathways, Effect of Lifestyle-related, Clinical and Demographic Parameters on Outcomes
- Trial name
- NCT07553104
- Where
- Denmark
- Volunteers
- 200 people
- Sponsor
- Aalborg University Hospital
Urinary Incontinence, Daytime Wetting
Brain Activity Among Children With Overactive Bladder and Daytime Urinary Incontinence and Healthy Children
The aim of this study is to investigate whether the activity in brain areas controlling the bladder is different among children suffering from Overactive Bladder (OAB) and Daytime Urinary Incontinence (DUI) compared to age- and…
- Conditions
- Urinary Incontinence, Daytime Wetting, Urination Disorders, Urination Involuntary
- Trial name
- NCT05989646
- Testing
- Sacral TENS
- Where
- 4 sites in Denmark
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- Aalborg University Hospital
Urinary Incontinence, Daytime Wetting
The Voided Urinary, Perineal, and Faecal Microbiota Among Children and Adolescents - the PpUF-study.
The aim of this study is to investigate whether the voided urinary, perineal/preputial, and the fecal microbiota are different between children suffering from Overactive Bladder (OAB) and Daytime Urinary Incontinence (DUI)…
- Conditions
- Urinary Incontinence, Daytime Wetting, Urination Disorders, Urologic Diseases
- Trial name
- NCT07535619
- Where
- 4 sites in Denmark
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Aalborg University Hospital
Fear of Cancer Recurrence, Renal Cell Carcinoma (Kidney Cancer)
Patient-partnered Research in Investigating Fear of Cancer Recurrence in Kidney Cancer
The goal of this observational study is to gather real-world information about Fear of Cancer Recurrence (FCR) following surgery in patients with renal cell carcinoma (RCC) and their partners/spouses by 1) establishing a panel…
- Trial name
- PP-RECURK (NCT07234656)
- Testing
- Phase 1: Establishment of a patient-partner panel, Phase 2: Feasibility testing of FCR questions, mode of administration and timing for investigating Fear of Cancer Recurrence
- Where
- 3 sites in Denmark
- Volunteers
- 105 people, healthy volunteers welcome
- Sponsor
- Brigitta Rasmussen Villumsen
Preeclampsia (PE)
Prevention of Preeclampsia in Denmark: A National Implementation Study
The goal of this clinical study is to learn if a new first-trimester screening program can better find pregnant women who are at high risk of developing preeclampsia and help prevent the condition with early treatment.
- Trial name
- PREPRED (NCT07485140)
- Testing
- First trimester screening for preeclampsia
- Where
- 3 sites in Denmark
- Volunteers
- 80,000 people, healthy volunteers welcome
- Sponsor
- Copenhagen University Hospital at Herlev
School Attendance, Academic Level
SchoolCare: A Social Intervention Introducing Telepresence Robots and School Navigation to Reduce School Fragmentation for Children Undergoing Cancer Treatment
Advances in pediatric cancer treatment have led to significant improvements in survival rates, where 5-year survival now exceeds 85%.
- Conditions
- School Attendance, Academic Level, Childhood Cancer Survivors, Social Well-being
- Trial name
- SchoolCare (NCT07398677)
- Testing
- Telepresence robot, School Navigator, Teleteaching and technical support
- Where
- 3 sites in Denmark
- Volunteers
- 128 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Developmental Dysplasia of the Hip
Reliability of Ultrasound Metrics Used in Hip Dysplasia Diagnostics - a Prospective Study
Several measurements are used to evaluate hip dysplasia in hip ultrasound of children. Despite having being used since the 1980s, reliability studies have failed to find acceptable reliaiblity values for the gold standard…
- Trial name
- NCT06233487
- Testing
- Repeat hip ultrasound measurements
- Where
- Denmark
- Volunteers
- 74 people, healthy volunteers welcome
- Sponsor
- Aarhus University Hospital
ADHD - Attention Deficit Disorder With Hyperactivity, Attention Concentration Difficulty
Danish Access to Support and Help (DASH): Increasing Access to an Evidence-based Intervention for Children With ADHD and Their Parents
The aim of this study is to devise implementation strategies for the New Forest Parenting Programme (NFPP) to support a community implementation model (NFPP-CIM) and test its feasibility and acceptability for parents and…
- Trial name
- DASH (NCT07339696)
- Testing
- New Forest Parenting Programme
- Where
- Denmark
- Volunteers
- 90 people
- Sponsor
- University of Aarhus
Recurrent Pregnancy Loss, Not Pregnant
Microchimerism in Patients With Recurrent Pregnancy Losses
This pilot study aims to evaluate if microchimeric cells in a patient with recurrent pregnancy loss (RPL) can be detected by the blood analysis for the presence of the DYS14 gene and the use of indel-panel methods and also, to…
- Trial name
- NCT05340556
- Testing
- Blood sample, Swap test
- Where
- Denmark
- Volunteers
- 32 people
- Sponsor
- Caroline Nørgaard-Pedersen
Neonatal Hyperbilirubinemia
Newborn Jaundice - An Investigation of Different Approaches to Light Therapy
Background Neonatal jaundice affects about 60% of full-term newborns in their first week. If untreated, it can lead to permanent brain damage. In Denmark, 2-5% of newborns require phototherapy, the standard treatment.
- Trial name
- NCT06702241
- Testing
- Continuous Phototherapy with a irradiance of 40 µW/cm2/nm from the overhead light, Continuos Phototherapy with a irradiance of 55 µW/cm2/nm from the overhead light, Continuous Phototherapy with a irradiance of 70 µW/cm2/nm from the overhead light
- Where
- 2 sites in Denmark
- Volunteers
- 116 people
- Sponsor
- Regionshospital Nordjylland
Heart Defects, Congenital, Mental Health Issue
Mind the Heart - Mental Health in Children and Adolescents With Congenital Heart Defects
The aim of the Mind the Heart study is to document the feasibility of an online parent/child administered screening model for mental disorders (MDs) in Danish children and adolescents with congenital heart disease (CHD).
- Trial name
- Mind the Heart (NCT05709470)
- Testing
- No-intervention
- Where
- Denmark
- Volunteers
- 4,800 people, healthy volunteers welcome
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Frailty in Older Adults, Functional Decline
Prevalence of Anticholinergics in Geriatric Patients With Acute Functional Deterioration
This study investigates the anticholinergic burden on patients seen in the Subacute mobile outpatient geriatric clinic in Aalborg, Denmark, between the years of 2024 and 2025.
- Conditions
- Frailty in Older Adults, Functional Decline, Anticholinergic Syndrome
- Trial name
- NCT07165574
- Testing
- No intervention as the study is observational
- Where
- Denmark
- Volunteers
- 100 people
- Sponsor
- Aalborg University Hospital