Clinical trials: sponsored by Georgetown University
Rett Syndrome
Measuring Impact of Computer Gaming on Arm Use in Rett Syndrome
Using a tele-research approach, we will recruit, enroll, guide and support carers and participants to engage in computer based activities (modified virtual reality) with the primary outcome of reducing stereotypies and increasing…
- Trial name
- NCT05012475
- Testing
- Modified Virtual Reality Gaming
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Georgetown University
Rett Syndrome
Technology-supported Motor Rehabilitation for People With Rett Syndrome
This study focuses on improving purposeful arm use while simultaneously reducing engagement in stereotypies. It is typically expected that the training period for this study will last about 6 months.
- Trial name
- TeMoRett (NCT07418905)
- Testing
- computer gaming
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- Georgetown University
Childhood Cancer, Survivorship
A Multilevel Intervention to Improve Adherence to Childhood Cancer Survivorship
More than 80% of childhood cancer survivors develop serious or life-threatening late effects after cancer therapy, but <20% receive recommended survivorship care offered at cancer center survivorship clinics.
- Conditions
- Childhood Cancer, Survivorship, Health Care Utilization, Health Knowledge, Attitudes, Practice
- Trial name
- BRIDGES (NCT05448560)
- Testing
- Multi-level Intervention of shared model of survivorship care, Comparison Group
- Where
- 4 sites in United States
- Volunteers
- 240 people
- Sponsor
- Georgetown University
Spirometry
The INTERvening for LUNG Health Trial
This research study is being done to find out whether a community health volunteer-delivered, multi-component program can improve lung health for people at risk of chronic respiratory diseases (such as asthma or COPD) in…
- Trial name
- INTERLUNG (NCT07540000)
- Testing
- Community health worker-delivered multi-component respiratory health intervention
- Where
- 2 sites in United States, Nepal
- Volunteers
- 800 people
- Sponsor
- Johns Hopkins University
Melanoma (Skin), Skin Cancer
Rural Adult and Youth Sun Protection Study
The purpose of this study is to help prevent skin cancer by improving the use of sun protective behaviors among youths living in rural communities in Utah and West Virginia.
- Trial name
- RAYS (NCT06439979)
- Testing
- RAYS Intervention
- Where
- 2 sites in United States
- Volunteers
- 843 people, healthy volunteers welcome
- Sponsor
- University of Utah
Mental Health
Does Social Media Impact Adolescent Mental Health?
The mental health of adolescents in the United States has seen a steep decline, roughly coinciding with the increasing popularity of social media and smartphones.
- Trial name
- NCT06049888
- Testing
- Restricted Social Media
- Where
- United States
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Georgetown University
Developmental Language Disorder, Language Delay
Using Neuroimaging and Behavioral Assessments to Understand Late Talking
Late talkers (LT), representing 10-20% of children under 3, demonstrate hallmark syntax and vocabulary deficits similar to preschoolers with developmental language disorder.
- Conditions
- Developmental Language Disorder, Language Delay, Language Development
- Trial name
- NCT06156865
- Testing
- Intervention to address late talking
- Where
- 2 sites in Canada
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Bronchopulmonary Dysplasia
Point of Care Lung Ultrasound in Preterm Infants With Respiratory Distress
The goal of this observational study is to learn about the role of bedside lung ultrasound in infants born prematurely with breathing problems.
- Trial name
- NCT05925075
- Testing
- Lung Ultrasound
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- Phoenix Children's Hospital
Mental Health Conditions, Developmental Disability
Evaluation of Telehealth Services on Mental Health Outcomes for People With Intellectual and Developmental Disabilities
Roughly 40% of those with intellectual and developmental disabilities (IDD) have mental health needs, which is twice the national average.
- Trial name
- NCT05336955
- Testing
- Intake and quarterly assessment:, Consultation & coping skills coaching:, 24-hour urgent crisis response and intervention:
- Where
- United States
- Volunteers
- 339 people
- Sponsor
- University of New Hampshire
Oral Pre-exposure Prophylaxis (PrEP), Long-acting Injectable Cabotegravir for PrEP
PathToScale: The PERSIST Trial
The purpose of this study is to identify the effectiveness of a bundle of strategies to support continuation of clients on pre-exposure prophylaxis, including long-acting injectable cabotegravir and oral pre-exposure prophylaxis…
- Trial name
- NCT07221747
- Testing
- Standard of Care (SoC), Enhanced continuation support package
- Where
- Malawi
- Volunteers
- 9,900 people, healthy volunteers welcome
- Sponsor
- Georgetown University
Executive Dysfunction, Autism Spectrum Disorder
Intervention-Induced Plasticity of Flexibility and Learning Mechanisms in ASD
This project explores the association between learning and cognitive flexibility by testing whether a cognitive behavioral intervention designed to improve flexibility in ASD changes learning and associated neural activation…
- Conditions
- Executive Dysfunction, Autism Spectrum Disorder, Adolescent Behavior
- Trial name
- NCT05131659
- Testing
- Executive function group therapy
- Where
- 2 sites in United States
- Volunteers
- 64 people
- Sponsor
- Children's National Research Institute
Parenting
Connect to Baby: A Pilot Study of a Parenting and Coparenting Program
The proposed project is a randomized control trial to assess a novel 6-session parenting and coparenting intervention for low-income parents of infants.
- Trial name
- CTB (NCT06179576)
- Testing
- Connect to Baby
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Georgetown University
Antibiotic-associated Diarrhea
Efficacy and Safety of BB-12 Supplemented Strawberry Yogurt For Healthy Children on Antibiotics
Probiotics are live microorganisms that, when administered in adequate amounts, confer a health benefit on the host. One of the most common indications for probiotic treatment is the prevention of antibiotic-associated diarrhea…
- Trial name
- PLAY ON (NCT03181516)
- Testing
- Bifidobacterium animalis subsp. lactis BB-12, Control
- Where
- United States
- Volunteers
- 255 people
- Sponsor
- Georgetown University
Ankyloglossia, Breastfeeding Support
Post-Procedural Manual Manipulation for Infant Ankyloglossia
The goal of this randomized control trial is to determine the impact of post-frenotomy manual manipulation on revision rates and breastfeeding outcomes.
- Trial name
- NCT06830148
- Testing
- Post-frenotomy manual manipulation
- Where
- United States
- Volunteers
- 110 people
- Sponsor
- Georgetown University
Migraine
Real-world Data Analysis of REN Treatment in Migraine Patients
Data analysis concerning four sets of metrics: A. Per-treatment patterns of REN use as a standalone treatment vs. in combination with medications. B.
- Trial name
- NCT04992897
- Testing
- Remote Electrical Neuromodulation (REN)
- Where
- 2 sites in United States, Israel
- Volunteers
- 12,151 people
- Sponsor
- Theranica
Oral Pre-exposure Prophylaxis (PrEP), Long-acting Injectable Cabotegravir for PrEP
PathToScale: An Implementation Evaluation
The purpose of this study is to evaluate the implementation and clinical outcomes of expanded pre-exposure prophylaxis delivery modalities and service delivery points offering long-acting injectable cabotegravir and oral…
- Trial name
- NCT06319105
- Testing
- Standard intervention: Offer PrEP choice
- Where
- Malawi
- Volunteers
- 9,900 people, healthy volunteers welcome
- Sponsor
- Georgetown University
Children
Safety of BB-12 Supplemented Strawberry Yogurt For Healthy Children
The investigators believe a readily available drink containing a high dose of probiotics has the potential to improve compliance through many of these mechanisms.
- Trial name
- NCT01652287
- Testing
- BB-12 supplemented strawberry yogurt, Strawberry flavored yogurt
- Where
- United States
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- Georgetown University
Prematurity, Premature Birth
Vibroacoustic Study of Lung Development in Newborn Infants
Investigators hypothesize that premature newborns with poor cardiopulmonary performance have higher morbidities and poorer physical and cognitive developmental outcomes.
- Conditions
- Prematurity, Premature Birth, Premature Lungs, Prematurity; Extreme
- Trial name
- NCT05827250
- Testing
- imPulse Tor
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- Level 42 AI, Inc.
Gender Relations, Reproductive Health
Global Early Adolescent Study - Kinshasa
The Global Early Adolescent Study (GEAS) is the first international study exploring how gender norms evolve over time and inform a spectrum of adolescent health outcomes, including sexual and mental health, through the adolescent…
- Trial name
- GEAS_KI (NCT03610568)
- Testing
- Growing up GREAT! Intervention
- Where
- Democratic Republic of the Congo
- Volunteers
- 2,862 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins Bloomberg School of Public Health
Lung Cancer
Educating Providers About Lung Screening
We are conducting a randomized trial to compare the Health Disparities module to an existing provider module on lung cancer screening to evaluate the impact on primary care providers' knowledge, attitudes, and lung cancer…
- Trial name
- NCT05064046
- Testing
- LuCa + Health Disparity module
- Where
- United States
- Volunteers
- 77 people, healthy volunteers welcome
- Sponsor
- Georgetown University