Clinical trials: sponsored by The Hong Kong Polytechnic University
Transcranial Direct Current Stimulation, Autistic Spectrum Disorder
Cumulative and Booster Effects of Multisession Prefrontal tDCS in ASD Adolescents
Autism spectrum disorder (ASD) is a neurodevelopmental disorder characterized by disturbances in communication, poor social skills, and aberrant behavior.
- Conditions
- Transcranial Direct Current Stimulation, Autistic Spectrum Disorder, Electroencephalography
- Trial name
- NCT06272669
- Testing
- Active-tDCS
- Where
- Hong Kong
- Volunteers
- 90 people
- Sponsor
- The Hong Kong Polytechnic University
ADHD or ADHD Traits
Development and Evaluation of a Digital Game Intervention Targeting Children Vulnerable to ADHD
The goal of this clinical trial is to learn whether a self-administered digital game can improve attention, memory, and planning and reduce ADHD-like symptoms in children aged 6-12 in Hong Kong who have subclinical or vulnerable…
- Trial name
- NCT07900048
- Testing
- Digital Game Intervention, Tetris
- Volunteers
- 100 people
- Sponsor
- The Hong Kong Polytechnic University
Intermittent Exotropia
Near Vergence Training for Distance Control in Intermittent Exotropia
Intermittent Exotropia (IXT) is a common type of eye misalignment where one eye periodically turns outward, and control is typically much worse when looking at objects far away than close up.
- Trial name
- NCT07642687
- Testing
- Home-based near eye training program
- Where
- Hong Kong
- Volunteers
- 42 people
- Sponsor
- The Hong Kong Polytechnic University
Autism Spectrum Disorder (ASD), Transcranial Direct Current Stimulation (tDCS)
Resting-State Functional Connectivity as a Predictor of tDCS Effects in Adolescents With Autism Spectrum Disorder
Background: Transcranial Direct Current Stimulation (tDCS) is a form of non-invasive brain stimulation that has aroused increased interests in the past decade.
- Conditions
- Autism Spectrum Disorder (ASD), Transcranial Direct Current Stimulation (tDCS), Electroencephalography
- Trial name
- NCT06878326
- Testing
- tDCS
- Where
- Hong Kong
- Volunteers
- 90 people
- Sponsor
- The Hong Kong Polytechnic University
Children With Medical Complexity (CMC), Symptom Management
Nurse-led Integrated Home Service to Support Parents in Symptom Management for Children Requiring Respiratory Support
The aims of this study are to test the effectiveness of a nurse-led integrated home health service to enhance parental self-efficacy in symptom management for children requiring respiratory support, and alongside identify factors…
- Conditions
- Children With Medical Complexity (CMC), Symptom Management, Nurse-led Supportive Care, Self Efficacy
- Trial name
- NCT07652268
- Testing
- Nurse-led integrated home service
- Where
- 2 sites in China, Hong Kong
- Volunteers
- 80 people
- Sponsor
- Dr Winsome Lam
Myopia
Myopia Control Using Novel Soft Contact Lenses
The goal of this study is to investigate the myopic control efficacy of two study soft contact lenses in children. Participants will be prescribed Lens A, Lens B or single vision contact lenses for the first year.
- Trial name
- NCT07547085
- Testing
- Lens A, Lens B
- Where
- Hong Kong
- Volunteers
- 126 people
- Sponsor
- The Hong Kong Polytechnic University
Child With Cancer, Muscular Atrophy
Nurse Parental Support Using a Mobile App in Symptom Management for CMC
Parents of children with medical complexity (CMC) are suffering from high level of stress. These CMC get multisystem diseases, including severe neurologic conditions or cancer, resulting in potential premature death.
- Conditions
- Child With Cancer, Muscular Atrophy, Child With Cerebral Palsy, Child With Medical Complexity
- Trial name
- NCT05765643
- Testing
- Nurse parental support in symptom management using a mobile health App
- Where
- 2 sites in Hong Kong
- Volunteers
- 96 people
- Sponsor
- The Hong Kong Polytechnic University
Child Development
Study of the Effects of Soy Exposure in Early Life on Bone Development and Gut Microbiota
In this project, the investigators aim to investigate the effects of soy consumption at early life on the development of gut microbiota and bone growth.
- Trial name
- NCT05763589
- Testing
- No intervention is involved
- Where
- China
- Volunteers
- 105 people
- Sponsor
- The Hong Kong Polytechnic University
Myopia
Combination Effect of Optical Defocus and Low Dose Atropine in Myopia Control
The purpose of the study is to investigate the combination effect of optical defocus and low dose atropine on myopia control in schoolchildren.
- Trial name
- NCT06358755
- Testing
- Defocus Incorporated Multiple Segments lenses, single vision spectacle lenses, Low dose atropine
- Where
- Hong Kong
- Volunteers
- 112 people, healthy volunteers welcome
- Sponsor
- The Hong Kong Polytechnic University
Myopia
Choroidal Response to the Modified Defocus Incorporated Multiple Segments Spectacle Lenses
The goal of this study is to investigate the short-term changes in choroidal thickness and efficacy of the study spectacle lenses in children.
- Trial name
- NCT07547072
- Testing
- Modified Defocus Incorporated Multiple Segments lens (D1), Modified Defocus Incorporated Multiple Segments lens (D2)
- Where
- Hong Kong
- Volunteers
- 108 people, healthy volunteers welcome
- Sponsor
- The Hong Kong Polytechnic University
Adolscent Idiopathic Scoliosis
Using Radiation-free Ultrasound for Screening Scoliosis Among School Children in Hong Kong to Reduce Unnecessary X-ray Exposure
Introduction Scoliosis is a three dimensional spinal deformity, in the coronal plane, sagittal and transverse planes. The conventional method for assessment of severity of scoliosis is by measuring the Cobb angle on x-ray…
- Trial name
- NCT07490886
- Where
- Hong Kong
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Joint Scoliosis Research Center of the Chinese University of Hong Kong and Nanjing University
COVID-19
Community-Based Health Education Programs for the Early Detection of, and Vaccination Against, COVID-19 and the Adoption of Self-Protective Measures of Hong Kong Residents
This study evaluates the community-based health education program in improving early testing for COVID-19, increasing vaccination acceptability and enhancing emergency preparedness and self-protection measures against COVID-19 in…
- Trial name
- NCT05539482
- Testing
- Community-based Health Education based on core intervention package, Health Information Sharing Group
- Where
- Hong Kong
- Volunteers
- 1,200 people, healthy volunteers welcome
- Sponsor
- The Hong Kong Polytechnic University
Attention Deficit Hyperactivity Disorder
Photography-Based Intervention for Children With Attention Deficit Hyperactivity Disorder
The aims are to evaluate the feasibility and acceptability of the photography-based intervention in children with Attention Deficit Hyperactivity Disorder (ADHD) and to provide preliminary evidence of its effectiveness in…
- Trial name
- NCT07647900
- Testing
- Photography-based psychoedication
- Where
- Hong Kong
- Volunteers
- 60 people
- Sponsor
- The Hong Kong Polytechnic University
Refractive Errors
Clinical Validation Study Protocol for SmartEyes Smart Optometry Measurement Device (Medical Device Clinical Validation Study)
This study aims to evaluate the SmartEyes smart refraction measurement device in two phases under real outpatient optometry room visits at Wuhan Children's Hospital.
- Trial name
- CVSP-SOMD (NCT07803094)
- Testing
- SmartEyes smart refraction measuring device, Topcon KR800, Subjective refraction
- Volunteers
- 200 people
- Sponsor
- The Hong Kong Polytechnic University
Smoking Cessation
Training Secondary School Students as Anti-smoke Ambassadors Using the Service-learning Model
Building the community's capacity by training youngsters to refer smokers to professional smoking cessation services offers a good strategy to support smoking cessation.
- Trial name
- hmrf-antismoke (NCT05897346)
- Testing
- 'Learning while serving' training program, Usual care
- Where
- Hong Kong
- Volunteers
- 368 people
- Sponsor
- The Hong Kong Polytechnic University
Virtual Reality, Social Interaction
Social Virtual-reality on Enhancing Social Interaction Skills in Children With Attention-deficit/Hyperactivity Disorder
The study targets children with diagnosed ADHD and aims to (1) develop a social virtual reality-based intervention, (2) investigate its effects on improving the social skills and executive functioning of inhibitions, emotional…
- Conditions
- Virtual Reality, Social Interaction, Attention-deficit/Hyperactivity Disorder
- Trial name
- NCT05778526
- Testing
- Virtual reality, Traditional social skills training
- Where
- Hong Kong
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- The Hong Kong Polytechnic University
ADHD, Social Skills
Immersive Gamified Virtual Reality-Based Training for Children With Attention Deficit Hyperactivity Disorder
This study evaluates a gamified virtual reality (VR) training program designed to help children with ADHD. Participants will be randomly assigned to one of three groups: the VR training group, a traditional training group, or a…
- Trial name
- NCT07784933
- Testing
- Immersive gamified virtual reality-based training (iGameVRT), Traditional social skills training
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- The Hong Kong Polytechnic University
Insomnia, ADHD
Efficacy of Cognitive Behavioural Therapy for Insomnia and Bright Light Therapy in Adolescents With ADHD, Insomnia, and Evening Chronotype
Attention-deficit/hyperactivity disorder (ADHD) is a neurodevelopmental disorder characterised by persistent inattention, hyperactivity, and impulsivity.
- Conditions
- Insomnia, ADHD, Eveningness, Chronotype
- Trial name
- NCT07767617
- Testing
- CBT-I with Bright Light Group
- Where
- Hong Kong
- Volunteers
- 150 people
- Sponsor
- The University of Hong Kong
Cancer Childhood, Brain Tumor
Musical Training: Promoting Brain Function in Children Who Have Survived Brain Tumours
This study aims to understand whether learning music can help improve brain function and quality of life in children who have recovered from brain tumours. A total of 236 children will join the study.
- Trial name
- NCT07769099
- Testing
- Musical Training Program
- Where
- Hong Kong
- Volunteers
- 236 people
- Sponsor
- The Hong Kong Polytechnic University
Chatbot, Large Language Model
Effects of a Large Language Model-Driven Chatbot on Reproductive Concerns After Cancer
Reproductive health has emerged as a critical yet overlooked concern among Adolescent and Young Adult (AYA) cancer survivors, given their compromised potential for biological parenthood in prime childbearing years.
- Conditions
- Chatbot, Large Language Model, Adolescent and Young Adult Cancer Survivors, Reproductive Health
- Trial name
- NCT07741266
- Testing
- Chatbot, Electronic brochure
- Where
- 2 sites in China, Hong Kong
- Volunteers
- 60 people
- Sponsor
- The Hong Kong Polytechnic University