Clinical trials: "Migraine-like" Headache
Migraine
To Evaluate the Blockade of CGRP in Preventing PACAP-38 Induced Migraine-like Attacks With AMG 334 in Migraine Patients
Phase I, Randomized, Parallel-group, Double-Blind, Placebo-Controlled, Single Dose Study to Evaluate the Blockade of CGRP Receptor by AMG 334 in Preventing PACAP-38 Induced Migraine-like Attacks in Migraine Patients.
- Trial name
- NCT02542605
- Testing
- Erenumab, PACAP-38 Challenge Agent
- Where
- 3 sites in United States, Belgium and 1 more
- Volunteers
- 35 people
- Sponsor
- Amgen
"Migraine-like" Headache
Prostaglandin E2 in Migraine Suffers Without Aura.
The hypothesis of this study is that Prostaglandin E2 (PGE2) induces headache and dilatation of brain vessels in migraine patients without aura.
- Trial name
- NCT01384812
- Testing
- dinoprostone, isoton sodium chloride
- Where
- Denmark
- Volunteers
- 12 people
- Sponsor
- Troels Wienecke
Migraine Headaches, Breathing Techniques
Effect of Breathing Techniques on Migraine Attacks and Severity
Background: Migraine is a very common neurobiological disorder caused by increased excitability of the Central Nervous System. It is among the causes of the highest morbidity worldwide.
- Trial name
- NCT05536635
- Testing
- breathing techniques
- Where
- Turkey (Türkiye)
- Volunteers
- 86 people
- Sponsor
- Dokuz Eylul University
Migraine in Children, Posttraumatic Headache
A Pilot Study of Intranasal Lidocaine in Acute Management of Pediatric Migraine
Headaches in children are very common and are a source of significant distress for the patient and their family. Migraines are the most common headache disorder in children and are associated with episodic pain and other symptoms…
- Trial name
- NCT03806595
- Testing
- Lidocaine 2% Injectable Solution, Normal Saline Flush, 0.9% Injectable Solution
- Where
- Canada
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Migraine Disorders, Migraine Without Aura
1H Magnetic Resonance Spectroscopy in Migraine Patients
To investigate the glutaminergic system in the onset of migraine-like attacks.
- Conditions
- Migraine Disorders, Migraine Without Aura, Headache Disorders, Primary, Headache Disorders
- Trial name
- NCT04220606
- Testing
- Glyceryl trinitrate (I.V. infusion 0.5 µg/kg/min over 20 min)
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- Leiden University Medical Center