Clinical trials: - Aortic Aneurysm
Cardiovascular Disease, Aortic Dissection
Additive Anti-inflammatory Action for Critically Ill Patients With Cardiovascular Surgery (Xuebijing) IV
XueBiJing, a Chinese herbal derived therapeutic, has been approved to treat severe infections (sepsis) in critically ill patients (China Food and Drug Administration; Beijing, China, Number Z20040033).
- Conditions
- Cardiovascular Disease, Aortic Dissection, Coronary Artery Disease, Valve Heart Disease
- Trial name
- NCT04993794
- Testing
- XueBiJing Injection, Normal saline
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Nanjing Medical University
Aortic Aneurysm, Abdominal
Enhanced Guidance for Endovascular Repair of Abdominal Aortic Aneurysm
An increasing incidence of abdominal aortic aneurysms (AAA) is observed in our ageing population. Since it is less invasive, endovascular repair (EVAR) by stent-graft (SG) insertion is frequently indicated in patients with…
- Trial name
- AAA 2D/3D II (NCT01824654)
- Testing
- Validation of the new rigid registration software, Validation of the new elastic registration software
- Where
- 2 sites in Canada
- Volunteers
- 25 people
- Sponsor
- Centre hospitalier de l'Université de Montréal (CHUM)
Appendicitis, Evidence of Cholecystectomy
Point of Care 3D Ultrasound for Various Applications: A Pilot Study
Summary 1. Purpose and Objective: The purpose of this study is to test the feasibility of rapid acquisition of point of care 3D ultrasound in obtaining abdominal and/or pelvic images.
- Conditions
- Appendicitis, Evidence of Cholecystectomy, Gallstones, Pregnancy, Ectopic
- Trial name
- NCT02831556
- Where
- United States
- Volunteers
- 174 people, healthy volunteers welcome
- Sponsor
- Duke University
Coagulopathy in Patients Having Thoraco-Abdominal Aneurysm Repair
Fibrinogen as an Alternative to FFP in Aortic Surgery.
Thoracoabdominal aneurysm (TAAA) repair is a major elective vascular operation associated with a large blood loss and potentially life-threatening clotting abnormalities.
- Trial name
- NCT00994045
- Testing
- Fibrinogen concentrate, Fresh Frozen Plasma
- Where
- United Kingdom
- Volunteers
- 20 people
- Sponsor
- University of Edinburgh
Aortic Dissection
Clinical Characteristics, Management and Outcomes of Chinese Patients With Acute Aortic Dissection
Data reported by the international registry of acute aortic dissection (IRAD) in not sufficient to reflect clinical characteristics of acute aortic dissection in China.
- Trial name
- CCMOCPAAD (NCT01552720)
- Where
- China
- Volunteers
- 5,000 people
- Sponsor
- Xijing Hospital
Aortic Aneurysm, Abdominal
Evaluation of the GORE® C3 Delivery System Module
This is an observational Registry designed to obtain early data on the use of the GORE® EXCLUDER® AAA Endoprosthesis with C3 Delivery System.
- Trial name
- NCT01398332
- Testing
- Stent graft (EXCLUDER)
- Where
- Germany
- Volunteers
- 399 people
- Sponsor
- W.L.Gore & Associates
Aortic Aneurysm, Abdominal, Carotid Stenosis
Screening and Access to Health Care for Vascular Disease
This is a pilot study designed to validate our methods of recruitment, screening and data collection in the community. The project will help to establish the feasibility of the study design to lay the groundwork for a potentially…
- Conditions
- Aortic Aneurysm, Abdominal, Carotid Stenosis, Peripheral Arterial Disease
- Trial name
- NCT01889485
- Where
- United States
- Volunteers
- 190 people, healthy volunteers welcome
- Sponsor
- Endeavor Health
Iliac Aneurysm, Aortic Aneurysm
Cook Iliac Branch Graft Post-market Registry
The Cook Iliac Branch Graft Post-market Registry will obtain case reports of physician experience with a CE-marked Cook Iliac Branch Graft to further confirm device safety and performance.
- Trial name
- NCT01055275
- Testing
- Implantation with a Cook Iliac Branch Graft
- Where
- Spain
- Volunteers
- 2 people
- Sponsor
- Cook Group Incorporated
Aortic Dissection, Aortic Dissection Aneurysm
Protective Effect of Ulinastatin and Thymosin α1 Against Negative Immune Dysregulation and Organ Dysfunction After Acute Aortic Dissection Surgery (PANDA XI)
Systemic inflammatory response syndrome (SIRS) and multiple organ dysfunction syndrome (MODS) are the major causes of death in patients with acute aortic syndrome (AAS).
- Trial name
- NCT06966687
- Testing
- Ulinastatin and Thymosin α1, Ulinastatin only
- Where
- 4 sites in China
- Volunteers
- 200 people
- Sponsor
- Nanjing Medical University
Hypoplastic Left Heart Syndrome, Aortic Coarctation
Cardiovascular Response to Maternal Hyperoxygenation in Fetal Congenital Heart Disease
Cardiovascular Response to Maternal Hyperoxygenation in Fetal Congenital Heart Disease
- Conditions
- Hypoplastic Left Heart Syndrome, Aortic Coarctation, Atrial Septal Aneurysm
- Trial name
- NCT03147014
- Testing
- Maternal hyperoxygenation
- Where
- China
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Beijing Anzhen Hospital
Thoracoabdominal Aortic Aneurysm
A PMCF Study in Patients With Thoracoabdominal Aortic Aneurysms Treated With E-nside TAAA Multibranch Stent Graft System (INNER-B-APAC)
The INNER-B-APAC post-market clinical follow-up study is undertaken to demonstrate the safety and clinical performance of the E-nside TAAA Multibranch Stent Graft System used in endovascular treatment of patients with…
- Trial name
- NCT05954793
- Where
- 8 sites in Australia, New Zealand and 1 more
- Volunteers
- 16 people
- Sponsor
- JOTEC GmbH
Ischemic Heart Disease, Aortic Stenosis, Severe
Influence of Lung Ultrasonography on the Prognosis and Postoperative Outcomes in Cardiac Surgical Patients
The goal of this interventional is to assess advantages of the ultrasound examination of the lungs in the early postoperative period in cardiac surgical patients after heart surgeries requiring cardiopulmonary bypass.
- Conditions
- Ischemic Heart Disease, Aortic Stenosis, Severe, Aortic Insufficiency, Mitral Stenosis
- Trial name
- NCT06377449
- Testing
- Ultrasound examination of the lungs
- Where
- Russia
- Volunteers
- 186 people
- Sponsor
- Saint Petersburg State University, Russia
Cardiovascular Diseases, Abdominal Aortic Aneurysm
Non-invasive Monitoring of Endovascular Repair of Abdominal Aortic Aneurysm (VBA)
This study evaluates a novel noninvasive method to dynamically monitor the effect of abdominal aortic aneurysm (AAA) and endovascular treatment of AAA (EVAR) on arterial pulse wave
- Trial name
- VBA (NCT03493074)
- Testing
- Noninvasive pulse wave analysis sensor, ECG-sensor
- Where
- Finland
- Volunteers
- 30 people
- Sponsor
- Tampere University Hospital
Aortic Arch Aneurysm, Penetrating Aortic Ulcer
Concave Supra-arch Branched Stent-Graft System for Endovascular Treatment of Aortic Arch Diseases
The objective of the study is to evaluate the safety and efficacy of the Lifetech Concave Supra-arch Branched Stent-Graft System for Endovascular Treatment of Aortic Arch Diseases
- Trial name
- NCT06520774
- Testing
- Concave Supra-arch Branched Stent-Graft System
- Where
- 17 sites in China, Germany
- Volunteers
- 103 people
- Sponsor
- Lifetech Scientific (Shenzhen) Co., Ltd.
Aortic Aneurysm, Thoracoabdominal
Post-market Observational Study Zenith® t-Branch™
The Zenith® t-Branch™ Thoracoabdominal Endovascular Graft Study is a post-market observational study to evaluate the performance of the Zenith® t-Branch™ in the treatment of thoracoabdominal aortic aneurysms in routine care.
- Trial name
- NCT02104089
- Testing
- Zenith® t-Branch™ Thoracoabdominal Endovascular Graft
- Where
- 3 sites in Germany, Sweden
- Volunteers
- 80 people
- Sponsor
- Cook Group Incorporated
Abdominal Aortic Aneurysm
Abdominal Aortic Aneurysm Sac Healing and Prevention of Endoleaks - Netherlands
To determine the safety and efficacy of IMPEDE-FX Embolization Plug and/or IMPEDE-FX Rapid Fill to fill an abdominal aortic aneurysm (AAA) sac outside of an endovascular aneurysm repair (EVAR) stent graft.
- Trial name
- AAA-SHAPE_NLD (NCT04751578)
- Testing
- IMPEDE-FX Embolization Plug
- Where
- 3 sites in Netherlands
- Volunteers
- 15 people
- Sponsor
- Shape Memory Medical, Inc.
Abdominal Aortic Aneurysms
Prospective Aneurysm Trial: High Angle Aorfix™ Bifurcated Stent Graft
Purpose of this study: The purpose of the study is to evaluate the safety and effectiveness of the Lombard Medical endovascular Aorfix™ AAA bifurcated stent graft in the treatment of abdominal aortic, aorto-iliac and common iliac…
- Trial name
- PYTHAGORAS (NCT00522535)
- Testing
- Open surgical repair, Stent Graft
- Where
- 38 sites in United States
- Volunteers
- 230 people
- Sponsor
- Lombard Medical
Aortic Dissection
Optimal Strategy for Repair of Type A Acute Aortic Dissection
Acute type A aortic dissection (TAAD) persists as a clinicopathologic entity with high lethality in the current era. Several procedures are presently used to repair the TAAAD.
- Trial name
- TARAD (NCT05912608)
- Testing
- Conservative TAAAD-R, Extensive TAAAD-R
- Where
- France
- Volunteers
- 900 people
- Sponsor
- Centre Cardiologique du Nord
Abdominal Aortic Aneurysm
Prevention of Incisional Hernia After Elective Open Abdominal Aortic Aneurysm (AAA) Repair
The aim of this study is to investigate the effect of the implantation of an Ultrapro® Mesh as prevention of incisional hernia after elective open abdominal aortic aneurysm repair.
- Trial name
- NCT01189708
- Testing
- Ultrapro® Mesh implantation, Standard wound closure
- Where
- Switzerland
- Volunteers
- 9 people
- Sponsor
- Cantonal Hospital of St. Gallen
Aortic Aneurysm
Prehabilitation for Aortic Aneurysm Surgery: Proof-of-concept Trial
This is a single-arm, proof-of-concept trial to examine the feasibility, acceptability, and preliminary efficacy of the Ready for Recovery program, a 6-week collaborative care intervention to help prepare individuals for repair…
- Trial name
- NCT06998498
- Testing
- Ready for Recovery
- Where
- United States
- Volunteers
- 13 people
- Sponsor
- Massachusetts General Hospital
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