Clinical trials: 18F- Fluorocholine
Thyroid Gland
Diagnostic Value of 18F-Choline PET/CT in Patients With a Thyroid Nodule With an Indeterminate Cytology: Pilot Study
The purpose of the study is to investigate the contribution of PET-CT with F18-choline in the diagnosis of thyroid nodule with indeterminate cytology in order to guide the best indication of surgical resection.
- Trial name
- CHOCOLATE (NCT02784223)
- Testing
- Radiation : PET-CT with F18-choline examination
- Where
- France
- Volunteers
- 107 people
- Sponsor
- Centre Francois Baclesse
Erdheim-Chester Disease, Langerhans Cell Histiocytosis
Uptake and Biodistribution of 18F-fluorocholine in Histiocytic Disorders by PET Imaging and Biopsy Measurement
The main purpose of this study is to discover how 18F-cholineFCH distributes in the body, and see if it can distinguish active histiocytes (tumor) from inflammatory (non- tumor) cells.
- Conditions
- Erdheim-Chester Disease, Langerhans Cell Histiocytosis, Histiocytic Disorders
- Trial name
- NCT02608619
- Testing
- F-choline PET Scan, FDG-PET, biopsy
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
Prostate Cancer
18F-FCH (Fluorocholine)-PET/MR in Staging of High-Risk Prostate Cancer
This is a single centre, single arm feasibility study of 18FCH PET-MR imaging for staging patients with high risk prostate cancer.
- Trial name
- NCT01993160
- Testing
- Fluorocholine (18F-FCH) Injection, PET scan, Whole body MRI
- Where
- Canada
- Volunteers
- 50 people
- Sponsor
- University Health Network, Toronto
High-grade Glioma of the Brain
PET Imaging of High-grade Glioma Using 18F-fluoromethylcholine: a Tool for the Early Detection of Tumour Recurrence After Combined Radiochemotherapy?
The aim of the study is to define preferential sites of tumour recurrence by observing tracer uptake in the tumour in sequential PET images with 18F-fluoromethylcholine (and perfusion MR, see also below).
- Trial name
- NCT00628940
- Testing
- PET images with 18F-fluoromethylcholine
- Where
- Belgium
- Volunteers
- 90 people
- Sponsor
- University Ghent
Prostate Cancer
Repeatability of Positron Emission Tomography (TEP) With fluorométhyl-(18F)-diméthyl-2-hydroxyéthyl-ammonium
Monocentric study. Objective : Determination of the repeatability of fluorocholine PET/CT in prostate cancer
- Trial name
- NCT03105869
- Testing
- fluorocholine PET/CT
- Volunteers
- 20 people
- Sponsor
- Poitiers University Hospital
Prostate Cancer, Prostatic Hyperplasia
Clinical Application of the J-PET Scanner Prototype
Positron emission tomography (PET), an advanced diagnostic imaging technique, exploits the annihilation of positrons (e+) to delineate pathological alterations within diseased tissues.
- Conditions
- Prostate Cancer, Prostatic Hyperplasia, Prostatic Neoplasms, Prostate Cancer Metastatic
- Trial name
- JPET2Clinic (NCT06242119)
- Testing
- J-PET scan
- Where
- Poland
- Volunteers
- 25 people
- Sponsor
- Jagiellonian University
Prostate Cancer
Cancer Localization in the Prostate With F-18 Fluorocholine Positron Emission Tomography
The purpose of this project is to develop and evaluate fluorine-18 (F-18) fluorocholine (FCH) positron emission tomography (PET) as an imaging technique that can be used to delineate malignant tumors in the prostate gland.
- Trial name
- NCT01310192
- Testing
- Fluourine-18 Fluoromethylcholine PET/CT Imaging
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Queen's Medical Center
Brain Metastases, Adult
Multi -paramEtric Imaging to Assess Treatment REsponse After Stereotactic Radiosurgery of Brain Metastases
After stereotactic radiosurgery (SRS) of brain metastases, patients undergo a standard brain magnetic resonance imaging (MRI) to assess treatment response 12 weeks after completion of treatment.
- Trial name
- METRE (NCT04626206)
- Volunteers
- 12 people
- Sponsor
- Royal Marsden NHS Foundation Trust
Medullary Thyroid Cancer
18F-Fluorocholine PET/CT in Medullary Thyroid Cancer
To assess the diagnostic accuracy of 18F-Fluorocholine PET/CT for the detection of medullary thyroid cancer in patients with primary and recurrent disease.
- Trial name
- NCT03643055
- Testing
- 18F-fluorocholine PET/CT
- Where
- Slovenia
- Volunteers
- 80 people
- Sponsor
- University Medical Centre Ljubljana
Parathyroid Diseases
Clinical Value of 18F-FCH PET in Localizing Parathyroid Lesions: Comparison With MIBI Scan.
This prospective study aims to 1. compare the detection rates among sonography, MIBI scan and 18F-FCH PET for localization of the parathyroid lesions including adenoma, hyperplasia or carcinoma; evaluate the usefulness of 18F-FCH…
- Trial name
- parathyroid (NCT03555487)
- Testing
- 18F-choline PET
- Where
- Taiwan
- Volunteers
- 103 people
- Sponsor
- National Taiwan University Hospital
Prostate Cancer
Comparing PET-CT Using C-11 Choline and 18F-Fluoromethylcholine in Patients With Metastatic Prostate Cancer
RATIONALE: Diagnostic procedures, such as positron emission tomography (PET) and computed tomography (CT) imaging, may help find and diagnose metastatic prostate cancer.
- Trial name
- NCT01132599
- Testing
- C-11 choline, 18F-fluoromethylcholine
- Where
- United Kingdom
- Sponsor
- Cancer Research UK
Parathyroid Adenomas
Expanded Access:18F-Fluorocholine for the Detection of Parathyroid Adenomas
This expanded access protocol is proposed to allow University of California San Francisco (UCSF) patients additional access to 18F-fluorocholine (FCH) Positron Emission Tomography (PET) imaging for localization of parathyroid…
- Trial name
- NCT07218224
- Testing
- 18F-Fluorocholine (FCH), Positron emission tomography (PET)
- Sponsor
- Thomas Hope
Prostate Cancer, Prostate Cancer Recurrent
F-18-PSMA-1007 Versus F-18-Fluorocholine PET in Patients With Biochemical Recurrence
This study evaluates the diagnostic performance and safety of F-18-PSMA-1007 and F-18-Fluorocholine PET/CT imaging in patients with suspected recurrence of prostate cancer after previous definitive treatment.
- Trial name
- NCT04102553
- Testing
- F-18-PSMA-1007, F-18-Fluorocholine
- Where
- 6 sites in France
- Volunteers
- 200 people
- Sponsor
- ABX advanced biochemical compounds GmbH
Prostate Cancer
Place of 68Ga-PSMA-11 PET-CT in the Therapeutic Decision at the End of the Initial Staging for High Risk Prostate Cancer Patients
Several studies have shown a great potential of 68Ga-PSMA PET in high risk prostate cancers patients and a high detection rate than 18F-Choline PET.
- Trial name
- TePSMAG-68 (NCT03344822)
- Testing
- 68Ga-PSMA-11, 18F-Choline PET-CT
- Where
- France
- Volunteers
- 33 people
- Sponsor
- Central Hospital, Nancy, France
Myocardial Infarction, Myocardial Ischemia
18F-fluorocholine PET-MR Imaging of Coronary Plaque Vulnerability
This study is designed as a prospective observational feasibility study. The investigators will study whether vulnerable plaques on OCT (fibrous cap ≤ 70 μm) show a locally increased uptake of 18F-choline on PET-MRI compared to…
- Conditions
- Myocardial Infarction, Myocardial Ischemia, Atherosclerosis, Coronary Artery Disease
- Trial name
- NCT03252990
- Testing
- PET-MRI, Optical Coherence Tomography
- Where
- Netherlands
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Maastricht University Medical Center
Prostatic Neoplasms
PRIME - PRostate Imaging for Margin Evaluation
This study will evaluate the feasibility of using intra-operative Cerenkov Luminescence Imaging (CLI) of prostatectomy specimens to determine tumour margin status.
- Trial name
- PRIME (NCT02151097)
- Where
- United Kingdom
- Volunteers
- 7 people
- Sponsor
- Lightpoint Medical Limited
Primary Hyperparathyroidism
18F-choline Positron-emission-tomography - Computed-tomography Compared to Conventional Imaging for Localizing Diseased Parathyroid Glands in Primary Hyperparathyroidism
The goal of this open, single-center, prospective, randomized, clinical study is to compare imaging with [18F]fluoromethyl-dimethyl-2-hydroxyethylammonium (18F-choline) positron-emission-tomography - computed-tomography…
- Trial name
- NCT07138820
- Testing
- Parathyroidectomy
- Where
- Sweden
- Volunteers
- 88 people
- Sponsor
- Region Skane
Prostate Cancer, 18F- Fluorocholine
Prospective Comparative Study for Patients With Biochemical Recurrence Prostate Cancer Detecting by 18F-JK-PSMA-7
The present study in patients with Prostate cancer and biochemical failure after surgery and/or radical-postoperative Radio Therapy (RT) will evaluate if PET/CT with 18F-JK-PSMA-7 compared to PET-CT 18F-Choline is able to…
- Conditions
- Prostate Cancer, 18F- Fluorocholine, PSMA PET, Radiotherapy
- Trial name
- MIP7 (NCT05622162)
- Testing
- Radiopharmaceutical 18F-JK-PSMA-7, Radiopharmaceutical 18F-Fluorocholine
- Where
- 2 sites in Italy
- Volunteers
- 106 people
- Sponsor
- ITEL Telecomunicazioni Srl
Hyperparathyroidism, Primary
18F-Fluorocholine Positron Emission Tomography (PET) for the Detection of Parathyroid Adenomas
This is a prospective single arm single center Phase III study evaluating the ability of 18F-fluorocholine to detect the location of parathyroid adenomas.
- Trial name
- NCT04895631
- Testing
- 18F-Fluorocholine, Positron emission tomography (PET)
- Where
- United States
- Volunteers
- 139 people
- Sponsor
- Thomas Hope
Hepatocellular Carcinoma
A Head-to-head Comparison of MRI, CT, 18F-FDGal and 18F-choline in Patients With Hepatocellular Carcinoma
Hepatocellular carcinoma (HCC) is the most common primary liver tumour and is the fourth leading cause of cancer-related death worldwide.
- Trial name
- NCT05359939
- Testing
- 18F-FDGal PET/CT versus 18F-choline PET/CT
- Where
- Denmark
- Volunteers
- 50 people
- Sponsor
- University of Aarhus