Clinical trials: 2019 Novel Coronavirus Infection
COVID-19
Treatment of Moderate to Severe Coronavirus Disease (COVID-19) in Hospitalized Patients
Investigational medications adjunct to clinical standard of care treatment will be assessed to evaluate safety and effectiveness as an anti-COVID-19 treatment.
- Trial name
- NCT04321993
- Testing
- Baricitinib (janus kinase inhibitor), Remdesivir (antiviral) + barictinib (janus kinase inhibitor), Remdesivir (antiviral)
- Where
- Canada
- Volunteers
- 363 people
- Sponsor
- Lisa Barrett
COVID-19
Anesthesia Preferences in the COVID-19 Pandemic: General Anesthesia or Regional Anesthesia?
As the COVID-19 pandemic continues, humanity has started to adapt to it. In our study, we aimed to examine the adaptation of anesthetists to the pandemic and its behavioral reflection on their work.
- Trial name
- NCT05531006
- Testing
- retrospective cohort study
- Where
- Turkey (Türkiye)
- Volunteers
- 1 people
- Sponsor
- Erol Olcok Corum Training and Research Hospital
Cardiac Involvement With COVID-19
Hearts of Athletes
The Hearts of Athletes study is being conducted to determine the heart involvement with COVID-19 in athletes. This study aims to enroll any Adult (18 years of age or greater) Athlete is defined as NCAA Collegiate Athlete…
- Trial name
- NCT04736004
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- Duke University
COVID-19
Pathogenesis of BTK-mediated Hyper-Inflammatory Responses in COVID-19 (RESPOND)
Background: Coronavirus disease 2019 (COVID-19) is an acute respiratory syndrome. It is caused by the SARS-CoV-2 virus. People with severe COVID-19 infection have a hyper-inflammatory response.
- Trial name
- NCT04394884
- Where
- 3 sites in United States
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Covid19
Prevent and Control COVID-19 Infection in Nursing Homes on the Risk of Death of Residents
The COVID epidemic has shown very high mortality among older people, especially among poly-morbid and dependent subjects. In addition to the classic risk factors of age, dependence and associated co-morbidities, community life…
- Trial name
- PIANO-COVID-19 (NCT04740658)
- Testing
- No intervention
- Where
- France
- Volunteers
- 12,166 people
- Sponsor
- University Hospital, Toulouse
COVID-19 Acute Respiratory Distress Syndrome, Extracorporeal Membrane Oxygenation Complication
Quality of Life 1y and 2 y After VV-ECMO for COVID-19
This study aims to investigate the quality of life and the outcome after veno-venous extracoporeal membrane oxygenation (ECMO) support fir severe acute respiratory syndrome (ARDS) in COVID-19 patients.
- Conditions
- COVID-19 Acute Respiratory Distress Syndrome, Extracorporeal Membrane Oxygenation Complication, Quality of Life, Death
- Trial name
- NCT05780255
- Testing
- VV-ECMO
- Where
- Belgium
- Volunteers
- 28 people
- Sponsor
- University Hospital, Ghent
COVID-19, Acute Hypoxemic Respiratory Failure
Early Versus Delayed Intubation of Patients With COVID-19
Although management of acute hypoxemic respiratory failure associated with coronavirus disease 2019 (COVID-19) often includes mechanical ventilation, the optimal timing of initiation of invasive mechanical ventilation remains…
- Trial name
- EUDOCO (NCT04632043)
- Testing
- Endotracheal intubation
- Where
- Greece
- Volunteers
- 2 people
- Sponsor
- Evangelismos Hospital
Coronavirus, COVID-19 Respiratory Infection
Protocol for Assistance to Patients With Long Covid-19 Undergoing Treatment With HD-tDCS
COVID-19 is an infectious disease which presents a heterogenous clinical presentation. Recent investigations suggest that people who were infected by COVID-19 often develop physical disabilities (i.e.
- Trial name
- NCT05289115
- Testing
- Experimental group/ Active HD-tDCS
- Where
- Brazil
- Volunteers
- 30 people
- Sponsor
- Federal University of Paraíba
COVID-19
Trial of Imatinib for Hospitalized Adults With COVID-19
This study is a randomized Double-Blind Placebo-Controlled Trial on the Safety and Efficacy of Imatinib for Hospitalized Adults with COVID-19
- Trial name
- NCT04394416
- Testing
- Imatinib
- Where
- United States
- Volunteers
- 21 people
- Sponsor
- University of Maryland, Baltimore
COVID-19, SARS CoV 2 Infection
Evaluation of Point-of-Care (EPOC) for COVID-19
EPOC is designed to examine the feasibility of conducting two point-of-care (POC) tests the LumiraDx SARS-CoV-2 Antibody Test and the RightSign COVID-19 IgG/IgM Rapid Test for SARS-CoV-2 antibodies and compare the reproducibility…
- Trial name
- (EPOC) (NCT05227404)
- Testing
- LumiraDX, RightSign, Case Control
- Where
- United States
- Volunteers
- 330 people
- Sponsor
- University of Minnesota
Menstrual Irregularity, Covid 19
Menstrual Cycle Characteristics of Healthcare Professionals
The Covid-19 pandemic has impacted healthcare workers physically and psychologically. The aim of this study is to examine whether there is a change in menstrual cycle characteristics during pandemia.
- Trial name
- NCT04413058
- Where
- Turkey (Türkiye)
- Volunteers
- 260 people, healthy volunteers welcome
- Sponsor
- Haydarpasa Numune Training and Research Hospital
Corona Virus Infection
Covid-19 Convalescent Plasma as Prevention and Treatment for Children With Underlying Medical Conditions
This study will provide access to investigational anti-SARS-CoV-2 human convalescent plasma for pediatric patients with underlying medical conditions (cardiovascular disease, lung disease, immunosuppression) who are either…
- Trial name
- NCT04462848
- Testing
- anti-SARS-CoV-2 human convalescent plasma
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- University of California, Los Angeles
COVID-19
Study to Evaluate the Efficacy and Safety of Maraviroc in SARS-CoV-2 Infection (COVID-19).
This is a bicentric, phase 2, randomized, open-label study to evaluate the efficacy and safety of maraviroc associated with standard treatment in hospitalized patients with pulmonary SARS-CoV-2 infection (COVID-19).
- Trial name
- MARACOVID (NCT04441385)
- Testing
- Maraviroc 300 mg, Standard care therapy
- Where
- 2 sites in Spain
- Volunteers
- 60 people
- Sponsor
- Hospital Universitario Infanta Leonor
Sars-CoV2, Covid-19
COPE - COVID-19 in Pregnancy and Early Childhood
Purpose: The emergence of a new coronavirus SARS-CoV-2 causing a novel infection in the human race resulting in a world-spanning pandemic came as a surprise and at a tremendous cost both for individual human lives as well as for…
- Conditions
- Sars-CoV2, Covid-19, Pregnancy Complications, Pregnancy Preterm
- Trial name
- COPE (NCT04433364)
- Testing
- biological samples, questionnaires and interviews
- Where
- 27 sites in Sweden
- Volunteers
- 3,834 people, healthy volunteers welcome
- Sponsor
- Sahlgrenska University Hospital
COVID-19, Symptoms and Signs
The Effect of Mobile Health Application Based on Omaha System on Symptoms and Quality of Life in COVID-19 Patients
Purpose: The aim of this study is to evaluate the effects of nursing interventions made with a mobile health application (COVOS) developed based on the Omaha System on the physical, psychosocial and cognitive symptoms and quality…
- Conditions
- COVID-19, Symptoms and Signs, Quality of Life
- Trial name
- NCT05258734
- Testing
- COVOS app, Standard Care
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Kocaeli University
Severe Acute Respiratory Syndrome Coronavirus 2 Infection
A Strain Change Study for SARS-CoV-2 rS Vaccines
The present study aims to investigate the safety and immunogenicity of the Novavax JN.1 subvariant vaccine SARS-CoV-2 rS adjuvanted with Matrix-M (NVX CoV2705) in previously vaccinated adults.
- Trial name
- COVID-19 (NCT06409663)
- Testing
- NVX-CoV2705 Vaccine
- Where
- 2 sites in United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Novavax
Covid19, SARS-CoV Infection
Caracterisation of COVID-19 Patients Hospitalized in Infectious Disease Department
The main objective of this cohort is to characterize COVID-19 patients hospitalized in infectious disease department. The collection of clinical and biological data from start of hospitalization to long-term follow up will…
- Trial name
- NCT04779021
- Testing
- Hospitalisation for SARS-COV2 infection
- Where
- 2 sites in France
- Volunteers
- 1,300 people
- Sponsor
- Centre Hospitalier Universitaire de Nice
Long COVID, Post COVID-19 Condition
Effect of Hi-OxSR for the Treatment of Post COVID Condition
The RECLAIM study platform will be used to explore whether the use of the Hi-OxSR device improves the symptoms of post covid cognitive dysfunction.
- Conditions
- Long COVID, Post COVID-19 Condition, Post Acute Sequelae of COVID-19
- Trial name
- RECLAIM-HiOxSR (NCT06928506)
- Testing
- Hi-OxSR device, Hi-Ox device
- Where
- 3 sites in Canada
- Volunteers
- 120 people
- Sponsor
- University Health Network, Toronto
COVID-19, Respiratory Failure
Compartmental Inflammation in Mechanically Ventilated Patients With COVID-19
The aim of the present study is to examine the inflammatory response in the pulmonary compartment and blood of critically ill patients admitted to the ICU with COVID-19.
- Trial name
- COV2ICU-DK (NCT04354584)
- Where
- Denmark
- Volunteers
- 20 people
- Sponsor
- Hvidovre University Hospital
COVID-19 Vaccine
A Study to Evaluate Immunogenicity and Safety of MVC-COV1901 Vaccine Compared With AZD1222
The primary objective of the study is to measure the anti-SARS-CoV-2 neutralizing antibody titres in adult participants, in particular elderly, so as to demonstrate immunogenic superiority of MVC-COV1901 to the active control…
- Trial name
- NCT05426343
- Testing
- MVC-COV1901, AZD1222
- Where
- Paraguay
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Medigen Vaccine Biologics Corp.
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.