Clinical trials: 65 Years Older
Acute Respiratory Infection
Expanded Diagnostic Strategy in Older Adults Hospitalized With Community-Acquired Acute Respiratory Infection
This study will evaluate whether an expanded diagnostic strategy can reduce antibiotic use in patients aged 65 years or older who are hospitalized with community-acquired acute respiratory infection, without negatively affecting…
- Trial name
- NeuBluMul (NCT07883902)
- Testing
- Expanded Diagnostic Strategy, Conventional Diagnostic Strategy
- Where
- Spain
- Volunteers
- 406 people
- Sponsor
- Santiago Lopez Gil
Vaccines, Pneumococcal Conjugate Vaccine
Study to Evaluate a 13-valent Pneumococcal Conjugate Vaccine in Elderly Subjects
There is evidence that aluminum phosphate (AlPO4) contained as an adjuvant in conjugate vaccines enhances the immune response in infants. There is no data so far evaluating whether this also applies to adults.
- Trial name
- NCT00269672
- Testing
- 13-valent Pneumococcal Conjugate Vaccine
- Volunteers
- 915 people, healthy volunteers welcome
- Sponsor
- Wyeth is now a wholly owned subsidiary of Pfizer
Older Adults (65 Years and Older), Geriatric
Understanding Dance for Falls Prevention
Falls are common among older adults, and can lead to both physical and emotional problems. The new World Falls Guidelines suggest that falls prevention programmes should take into account a person's individual priorities and…
- Conditions
- Older Adults (65 Years and Older), Geriatric, Rehabilitation
- Trial name
- NCT07821567
- Testing
- Dance, Resistance exercise
- Where
- United Kingdom
- Volunteers
- 23 people
- Sponsor
- Guy's and St Thomas' NHS Foundation Trust
Advanced Soft-tissue Sarcoma, Metastatic Soft-tissue Sarcoma
Comparison of Oral Cyclophosphamide vs Doxorubicin in ≥65 Years Old Advanced or Metastatic Soft Tissue Sarcoma Patients
Most advanced or metastatic soft tissue sarcoma (STS) are unfortunately incurable, making the preservation of the patient's quality of life a major goal, along with prolonging survival.
- Trial name
- GERICO14 (NCT04757337)
- Testing
- Doxorubicin, Cyclophosphamide
- Where
- France
- Volunteers
- 214 people
- Sponsor
- UNICANCER
Influenza
A Study Evaluating the Safety and Tolerability of a Seasonal Influenza Vaccine Containing LIQ001
This study is designed to evaluate the safety, tolerability, and immune response of LIQ001 mixed with a commercially available seasonal influenza vaccine (Fluzone) in two populations of subjects; healthy adult subjects 18 to 49…
- Trial name
- LIfT (NCT01224262)
- Testing
- Fluzone® (2010/2011 Inactivated Trivalent Influenza Vaccine), LIQ001 (0.45mg), LIQ001 (1.8mg)
- Where
- United States
- Volunteers
- 152 people, healthy volunteers welcome
- Sponsor
- Liquidia Technologies, Inc.
Chronic Disease, Chronic Pain (Back / Neck)
Nature-based Intervention for Chronic Pain in Older People
The goal of this clinical trial is to learn if a nature-based intervention program has positive effects on the physical and psychosocial health in a group of older participants with chronic non-specific lower back pain.
- Conditions
- Chronic Disease, Chronic Pain (Back / Neck), Older Adults (65 Years and Older)
- Trial name
- PARC-2 (NCT07002853)
- Testing
- Nature-based Intervention
- Where
- Canada
- Volunteers
- 15 people
- Sponsor
- Université du Québec à Chicoutimi
Primary Hyperparathyroidism
Surgery for Primary Hyperparathyroidism (pHPT) in Patients Older Than 65 Years Compared With Follow-up
General consensus and contemporary guidelines, recommend surgery for primary hyperparathyroidism (pHPT)for all patients below the age of 50, for patients with pronounced hypercalcemia and for patients with organ complications to…
- Trial name
- NCT01087619
- Testing
- Parathyroid surgery
- Where
- Sweden
- Volunteers
- 102 people
- Sponsor
- Region Skane
Digital Storytelling, Health Promotion
The Effect of a Digital Storytelling Program on Fall Among Community-Dwelling Older Adults
This study aims to examine fall behaviors, fear of falling, and self-efficacy levels in older adults living at home through a digital storytelling program based on Pender's Health Promotion Model, and to evaluate the effect of…
- Conditions
- Digital Storytelling, Health Promotion, Older Adults (65 Years and Older)
- Trial name
- NCT07628816
- Testing
- Digital Storytelling Program Based on Pender's Health Promotion Model on Fall Behaviors, Fear of Falling, and Self-Efficacy
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Kirsehir Ahi Evran Universitesi
Influenza A, Influenza B, Influenza Vaccination
Phase 2/3 Clinical Trial to Evaluate the Immunogenicity and Safety of GC3114B in Adults Aged 65 Years or Older
This is a multicenter, randomized, double-blind, active-controlled, parallel-group clinical trial in adults aged 65 years or older.
- Trial name
- GC3114B (NCT07883928)
- Testing
- vaccination of GC3114B, Vaccination of Efluelda
- Where
- South Korea
- Volunteers
- 1,806 people, healthy volunteers welcome
- Sponsor
- GC Biopharma Corp
Lung Neoplasm Malignant, Mesothelioma; Lung
Feasibility Trial of a Personalised Nutrition and Activity Programme for People With Lung Cancer Over 65 Years
People with cancer affecting the lungs tend to be older and frailer compared to people with other cancers. As a result, they may have poorer quality of life and are less able to tolerate treatments for their cancer, such as…
- Trial name
- CanBenefitII (NCT05404022)
- Testing
- Tailored nutrition and physical activity programme
- Where
- 2 sites in United Kingdom
- Volunteers
- 11 people
- Sponsor
- University of Hull
Influenza Vaccination, Older Adults (65 Years and Older)
Influenza Vaccine Immunogenicity in Repeatedly Vaccinated Older Adults
The goal of this clinical trial is to compare immune responses to different influenza vaccine formulations in older adults and to understand how immune aging and repeated annual influenza vaccination affect these responses.
- Conditions
- Influenza Vaccination, Older Adults (65 Years and Older), Immunosenescence, Immunogenicity
- Trial name
- NCT07838298
- Testing
- Standard dose influenza vaccine, MF59 adjuvanted influenza vaccine, High dose influenza vaccine
- Where
- South Korea
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Korea University Guro Hospital
Older Adults, Balance, Dance
Dance and Blood Flow Restriction as Balance Training for Older Women
Falls are one of the leading causes of hospitalization and mortality among older adults (aged 65+) in Canada. Falls result from postural instability following age-related declines in muscle strength which begin in the 5th decade…
- Conditions
- Older Adults, Balance, Dance, Blood Flow Restriction (BFR) Training Effects, Telehealth
- Trial name
- NCT07011784
- Testing
- Blood flow restriction in combination with dance classes, Dance classes alone
- Where
- Canada
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Concordia University, Montreal
Type 2 Diabetes Treated With Insulin
Premixed vs Basal Bolus Insulin Therapy in Older Patients With Type 2 Diabetes
The purpose of this study is to compare efficacy and security of premixed insulin treatment vs basal bolus insulin treatment in older patients with poorly controlled type 2 diabetes.
- Trial name
- NCT04739241
- Testing
- premixed insulin therapy, basal bolus insulin therapy
- Volunteers
- 60 people
- Sponsor
- Consorci Sanitari Integral
Older Adults, Appetitive Behaviour
Oral Processing and Appetite in Older Adults
The goal of this observational study is to learn about changes in oral processing and appetite in older adults aged 65+ years old.
- Conditions
- Older Adults, Appetitive Behaviour, Food Intake, Oral Processing
- Trial name
- NCT05671003
- Where
- United Kingdom
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- University of Reading
Fall, Daily Activities
Incidence and Factors of Functional Decline After Emergency Department Discharge in Older Adults With Falls
The goal of this observational study is to learn about changes in activities of daily living (ADL) in older adults after being discharged from the emergency department (ED) following a fall.
- Conditions
- Fall, Daily Activities, Functional Decline, Older Adults (65 Years and Older)
- Trial name
- FALL-ADL (NCT07163715)
- Volunteers
- 280 people
- Sponsor
- Ege University
Older Adults (65 Years and Older)
"Income Level and Its Effect in Older Adults"
The aim of this study was to examine the effect of income level on cognitive function, pain, balance, lower extremity performance, gait, occupational competence, depression, and health-promoting behaviors in older adults.
- Trial name
- NCT07248293
- Testing
- Behavioral Treatment, behavioral
- Where
- Turkey (Türkiye)
- Volunteers
- 223 people, healthy volunteers welcome
- Sponsor
- Begüm AKAR
Immune Deficiency
Efficacy of QBKPN Site-Specific Immunomodulator in Improving Innate Immune Function & Reducing Respiratory Tract Infection in Older Adults
This study is designed to test whether QBKPN SSI can improve immune function in older adults, including how well it can protect against respiratory and other infections, whether it improves the body's response to COVID-19…
- Trial name
- RESILIENCE (NCT05421325)
- Testing
- QBKPN SSI
- Where
- Canada
- Volunteers
- 72 people
- Sponsor
- Qu Biologics Inc.
Chronic Kidney Disease (CKD), Older Adults (65 Years and Older)
Trazodone and the Risk of Serious Adverse Events
This is a population-based retrospective, new-user, active comparator cohort study assessing whether initiating a new outpatient prescription of trazodone (>75-150 mg/day), compared to a lower dose (25-75 mg/day) is associated…
- Trial name
- NCT07381101
- Testing
- Trazodone HCl
- Where
- Canada
- Volunteers
- 31,459 people
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Older People
Cognitive Exergame Training on Dual-Task Cost and Balance Stability in Older Adults
Balance stability requires both motor and cognitive (mental) functions working together. Balance stability may decrease when performing two tasks at the same time (dual task), as cognitive and motor tasks compete for performing a…
- Trial name
- NCT05395676
- Testing
- Exergame home training programme
- Where
- United Kingdom
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Loughborough University
Comorbidities and Coexisting Conditions, Ethics
eCardiacRehab - a Hybrid Patient-Centered eHealth Programme
The overall aim of eCardiacRehab trial is to meet rehabilitation needs of patients with coronary artery disease (CAD) regardless of their access to traditional place-based rehabilitation by developing and evaluating the efficacy…
- Conditions
- Comorbidities and Coexisting Conditions, Ethics, Continuity of Patient Care, Older Adults (65 Years and Older)
- Trial name
- eCardiacRehab (NCT07590635)
- Testing
- eCardiacRehab
- Where
- Norway
- Volunteers
- 1,000 people
- Sponsor
- Haukeland University Hospital