Clinical trials: A Single-blind Randomized Controlled Trial
Healthy
A SAD/MAD Study to Evaluate the Safety, Tolerability, PK of MT200605 in Healthy Subjects
The goal of this randomized, double-blind, placebo control, Phase I clinical trial is to evaluate the Safety, Tolerability, and Pharmacokinetics after Single Ascending Dose (SAD) and multiple Ascending Dose (MAD) of MT200605 for…
- Trial name
- NCT05948774
- Testing
- MT200605 for Injection
- Where
- China
- Volunteers
- 61 people, healthy volunteers welcome
- Sponsor
- Shaanxi Micot Pharmaceutical Technology Co., Ltd.
Healthy Volunteers, Chronic Pain Syndrome
A Study to Investigate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics After Oral Administration of AJH-2947 in Healthy Korean and/or Caucasian Adult Male Subjects
The purpose of this randomized, double-blind, placebo-controlled Phase 1 study was to evaluate the safety, tolerability, pharmacokinetics, and pharmacodynamics of single and multiple oral doses of AJH-2947 in healthy Korean or…
- Trial name
- NCT06155487
- Where
- South Korea
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- JMackem Co., Ltd
Exercise Addiction, Control Condition
Effects of Moderate Exercise And Interval Exercise On Sleep Quality
This study aimed to explore the effects of a single bout of moderate- aerobic continuous exercise (MACE) and high-intensity intermittent exercise (HIIE) on sleep during continuous night shifts in medical shift workers with mild…
- Trial name
- EX&sleep (NCT06638359)
- Testing
- moderate exercise, interval exercise
- Where
- Taiwan
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- National Taiwan Sport University
Healthy Volunteers
Clinical Trial of Naoqingzhiming Tablets in Healthy Chinese Subjects
A single-center, randomized, double-blind, placebo-controlled, dose escalation safety, tolerability, and pharmacokinetic phase I clinical study of Naoqingzhiming Tablets in Chinese healthy subjects.
- Trial name
- NCT04902534
- Testing
- Naoqingzhiming Tablets (contains echinacoside 180mg)
- Where
- China
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- The Affiliated Hospital of Qingdao University
Healthy
Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of DWP14012 After Oral Administration in Healthy Male Volunteers
This is a dose block-randomized, double-blind, placebo- and active-controlled, single and multiple dosing, dose-escalation clinical phase 1 trial to investigate the safety, tolerability, pharmacokinetics and pharmacodynamics of…
- Trial name
- NCT02757144
- Testing
- DWP14012, Esomeprazole
- Where
- South Korea
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Daewoong Pharmaceutical Co. LTD.
Healthy Volunteers
A Phase 1 Trial To Assess The Safety And Pharmacokinetics Of Single, Ascending, Oral Doses Of Dimebon In Healthy Adults
The purpose of this study is to evaluate the safety, tolerability and pharmacokinetics of Dimebon following single ascending doses.
- Trial name
- NCT00907322
- Testing
- Dimebon
- Where
- Belgium
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Pfizer
Abdominoplasty
Cohera TissuGlu® Surgical Adhesive in the Management of Wound Drainage
This study is designed to evaluate the safety and efficacy of the device while reducing the amount of drainage from surgical wounds following large flap surgical procedures, in this case abdominoplasty, as compared to the…
- Trial name
- NCT01526954
- Testing
- TissuGlu Surgical Adhesive
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Cohera Medical, Inc.
Healthy
Pharmacokinetics of Oral Desipramine With and Without Concomitant Administration of Crobenetine Infusion in Healthy Male Subjects
To assess the steady state pharmacokinetics of Desipramine with/without concomitant administration of Crobenetine.
- Trial name
- NCT02273466
- Testing
- Desipramine tablet, Crobenetine infusion
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Boehringer Ingelheim
Healthy Subjects
Evaluation of Safety, Tolerability & Pharmacokinetics of JYP0061 in Healthy Adults.
The goal of this clinical trial is to evaluate the safety, tolerability and pharmacokinetic characteristics of JYP0061 in healthy adult subjects.
- Trial name
- NCT06137911
- Testing
- JYP0061
- Where
- China
- Volunteers
- 94 people, healthy volunteers welcome
- Sponsor
- Guangzhou JOYO Pharma Co., Ltd
Healthy Subjects, Cold Urticaria
A Phase 1 Study of GTX-B001 in Healthy Subjects and Patients With Chronic Inducible Urticaria
This is a first-in-human study aimed at determining the safety of a single dose of GTX-B001 in healthy participants and in people with chronic inducible urticaria.
- Conditions
- Healthy Subjects, Cold Urticaria, Symptomatic Dermographism, Chronic Inducible Urticaria
- Trial name
- CHILL-MC (NCT07181369)
- Testing
- GTX-B001, Normal Saline
- Where
- 5 sites in Germany
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Granular Therapeutics Limited
Asthma
A Trial of HBM9378 in Healthy Chinese Subjects
The objective is to evaluate the safety, tolerability and pharmacokinetic profile of a single subcutaneous injection of HBM9378 (SKB378) at different doses in healthy Chinese subjects.
- Trial name
- NCT05790694
- Testing
- HBM9378 (SKB378) Injection
- Where
- China
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Harbour BioMed (Guangzhou) Co. Ltd.
TTR-mediated Amyloidosis
Trial to Evaluate Safety, Tolerability, and Parmacokinetics of ALN-TTR02 in Healthy Volunteer Subjects
The purpose of this study is to determine the safety, tolerability, pharmacokinetics and pharmacodynamics of a single dose of ALN-TTR02 in healthy volunteer subjects.
- Trial name
- NCT01559077
- Testing
- ALN-TTR02, Sterile Normal Saline (0.9% NaCl)
- Where
- 2 sites in United Kingdom
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- Alnylam Pharmaceuticals
Vaccine Effectiveness, HPV Vaccination
A Trial to Establish Non-inferiority of Immunogenicity of a Single-dose of CERVAVAC® Quadrivalent HPV Vaccine Compared to the Gardasil® Quadrivalent Vaccine Among Girls and Boys Aged 9 to 14 Years and in Girls/Women Aged 15 to 20 Years in Zambia
The goal of this study is to compare the immune response of the single dose of the CERVAVAC vaccine with the single dose of Gardasil vaccine in girls/women aged 9 to 20 and boys aged 9 to 14 at 6 months, 12 months and 24 months…
- Conditions
- Vaccine Effectiveness, HPV Vaccination, Single Dose, Immunogenicity
- Trial name
- CervALONE (NCT07256912)
- Testing
- quadrivalent HPV vaccine
- Where
- Zambia
- Volunteers
- 1,266 people, healthy volunteers welcome
- Sponsor
- International Agency for Research on Cancer
Healthy
Comparison of Skin Thickness Under Treatment With Pimecrolimus 1% Cream, Hydrocortisonacetat 1% Cream, Betamethasonvalerat 0,1% Cream and Clobetasol-17-propionat 0,05% Cream Assessed by Optical Coherence Tomography (OCT) and 20-MHZ Ultrasound
to compare the atrophogenic potentials of pimecrolimus 1% cream, hydrocortisonacetat 1% cream, betamethasonvalerat 0,1% cream and clobetasol-17-Propionat 0,05% cream
- Trial name
- OCT (NCT00655512)
- Testing
- pimecrolimus 1% cream, hydrocortisonacetat 1% cream, betamethasonvalerat 0,1% cream
- Where
- Germany
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Technische Universität Dresden
Alveolar Bone Resorption, Alveolar Ridge Enlargement
Is Cross-linked Hyaluronic Acid a Biologic Alternative for Alveolar Ridge Preservation?
Even after atraumatic tooth removal and/or immediate implant placement, some reduction of the alveolar ridge dimension is expected.
- Conditions
- Alveolar Bone Resorption, Alveolar Ridge Enlargement, Tooth Extraction, Hyaluronic Acid
- Trial name
- NCT07496437
- Testing
- DBBM + FGG, Hyaluronic acid + collagen sponge + FGG
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Medical University of Vienna
Meningitis, Meningococcal
Immunogenicity and Safety of Meningococcal ACYW135 Polysaccharide Conjugate Vaccine in Volunteers Aged From 3 to 35 Months
The purpose of this study is to evaluate the immunogenicity and safety of Meningococcal ACYW135 Polysaccharide Conjugate Vaccine in healthy volunteers aged from 3 months to 35 years.
- Trial name
- NCT05229536
- Testing
- Meningococcal ACYW135 Polysaccharide Conjugate Vaccine
- Where
- China
- Volunteers
- 720 people, healthy volunteers welcome
- Sponsor
- Beijing Zhifei Lvzhu Biopharmaceutical Co., Ltd
Anemia
Pharmacokinetics Study of CKD-11101 and NESP After SC Administration in Health Male Volunteers
The purpose of this study is to investigate the pharmacokinetics of CKD-11101 and NESP after SC administration in health male volunteers
- Trial name
- NCT01685671
- Testing
- NESP 60μg, CKD-11101 60μg
- Where
- South Korea
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Chong Kun Dang Pharmaceutical
Healthy
A Single Ascending Dose Trial Assessing Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of ZP7570
This is a randomized, double-blind, placebo-controlled, single ascending dose trial in healthy subjects, randomized to ZP7570 or placebo within each cohort.
- Trial name
- NCT03994549
- Testing
- Dual GLP-1/GLP-2 Receptor agonists
- Where
- Germany
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Zealand Pharma
Glabellar Lines
Safety and Efficacy of CKDB-501A in Subjects With Moderate-to-severe Glabellar Lines
A single-center, randomized, double-blind, single-injection, active-controlled, parallel-design study to evaluate the safety and efficacy of CKDB-501A in Glabellar lines.
- Trial name
- NCT05292638
- Testing
- CKDB-501A, Botox®
- Where
- South Korea
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- CKD Bio Corporation
Functional Constipation
Phase 1/2a Trial of YH12852 in Healthy Subjects and Patients With Functional Constipation
A randomized, double-blind/open-label, placebo/active-controlled, single/multiple dose, parallel, phase 1/2a trial to evaluate the safety, tolerability, pharmacokinetics and pharmacodynamics of YH12852 in healthy subjects and…
- Trial name
- NCT02538367
- Testing
- YH12852 IR 0.05mg, YH12852 IR 0.1mg, YH12852 IR 0.3mg
- Where
- South Korea
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Yuhan Corporation