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Generalized Anxiety Disorder
Electroacupuncture for Generalized Anxiety Disorder: Clinical Efficacy and Neuroimaging Mechanisms
This study aims to evaluate the clinical efficacy and safety of electroacupuncture (EA) as an adjunctive treatment for generalized anxiety disorder (GAD).
- Trial name
- NCT07392645
- Testing
- Electroacupuncture (EA), Medication
- Where
- China
- Volunteers
- 123 people, healthy volunteers welcome
- Sponsor
- Lishu Gao
Dental Plaque, Gingivitis
A Clinical Study to Evaluate the Efficacy of a Cetylpyridinium Chloride Mouthwash in Improving Gingival Health and Reducing Plaque Accumulation
The aim of this 12-week clinical study is to evaluate the ability of an experimental mouthwash, containing 0.085 percent (%) Cetylpyridinium chloride (CPC) as an adjunct to toothbrushing with a regular fluoride toothpaste, to…
- Trial name
- NCT06933368
- Testing
- Crest Cavity Protection Toothpaste, Experimental Mouthwash
- Where
- United States
- Volunteers
- 138 people, healthy volunteers welcome
- Sponsor
- HALEON
DOCK8 Deficiency
Pilot Study of Reduced-Intensity Hematopoietic Stem Cell Transplant of DOCK8 Deficiency
Background: -DOCK8 deficiency is a genetic disorder that affects the immune system and can lead to severe recurrent infections and possible death from infections or certain types of cancers, including blood cancers.
- Trial name
- NCT01176006
- Testing
- Reduced-intensity hematopoietic stem cell, Fludarabine(Fludara, Berlex Laboratories), Cyclophosphamide(CTX, Cytoxan)
- Where
- United States
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- National Cancer Institute (NCI)
Alcohol Consumption
Effect of Acute Alcohol Intoxication on Neural Processes During Decisions to Engage in HIV Risk Behaviors
Background: People who binge drink are more likely to have risky sexual encounters, and alcohol changes brain activity associated with reward decisions related to those behaviors.
- Trial name
- NCT04360018
- Testing
- Alcohol beverage
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- National Institute on Alcohol Abuse and Alcoholism (NIAAA)
Melanoma
Community Based Strategies for Early Detection of Melanoma
The purpose of this study is to pilot the use of community education and digital dermatology to increase the early detection of curable melanomas.
- Trial name
- NCT04799106
- Testing
- Community Based Strategies for Early Detection of Melanoma
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Cedars-Sinai Medical Center
Shoulder Injuries and Disorders, Elbow Injuries and Disorders
Cross-Cultural Adaptation, Validity, and Reliability of the Functional Arm Scale for Throwers (FAST) in Throwing Athletes
The Functional Arm Scale for Throwers (FAST) is a patient-reported outcome measure that assesses upper extremity function in overhead throwing athletes.
- Conditions
- Shoulder Injuries and Disorders, Elbow Injuries and Disorders, Athletic Injuries
- Trial name
- NCT07893899
- Where
- Turkey (Türkiye)
- Volunteers
- 217 people, healthy volunteers welcome
- Sponsor
- Elif Turgut
Primary Sjögren Syndrome, Sarcopenia
Possible Sarcopenia, Sarcopenia, and Functional Status in Patients With Primary Sjögren's Syndrome
The aim of this study is to evaluate the frequency of probable sarcopenia and sarcopenia in patients with primary Sjögren syndrome and to investigate the effects of sarcopenia on functional status, muscle strength, and quality of…
- Trial name
- NCT07804719
- Testing
- dexa, hand grip strength, myostatin, follistatin
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Antalya Training and Research Hospital
Pneumococcal Disease
A Study to Learn About the Safety of an Expanded Pneumococcal Vaccine in Healthy Infants
The purpose of this study is to learn about the safety of a new pneumococcal vaccine and how the new pneumococcal vaccine helps to fight against germs that can cause pneumonia (lung infections), meningitis (brain infections), and…
- Trial name
- NCT07573462
- Testing
- PG4, 20-valent pneumococcal conjugate vaccine (20vPnC)
- Where
- 78 sites in United States, Argentina and 8 more
- Volunteers
- 2,400 people, healthy volunteers welcome
- Sponsor
- Pfizer
Class I/II Obesity
Translational Health Research Into Vascular and Neurocognitive Effects of Weight Loss
The goal of this clinical trial is to learn about the nature of brain abnormalities associated with excess body fat in healthy adults aged 35-55.
- Trial name
- THRIVE (NCT07592546)
- Testing
- semaglutide
- Where
- Canada
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Alain Dagher
Charcot Marie Tooth Disease
Natural History Evaluation of Charcot Marie Tooth Disease (CMT) Types CMT1B, CMT2A, CMT4A, CMT4C, and Others
This is an observational longitudinal study to determine the natural history and genotype-phenotype correlations of disease causing mutations in Charcot Marie Tooth disease (CMT) type 1B (CMT1B), 2A (CMT2A), 4A (CMT4A), and 4C…
- Trial name
- INC-6601 (NCT01193075)
- Where
- 24 sites in United States, Australia and 4 more
- Volunteers
- 5,000 people, healthy volunteers welcome
- Sponsor
- Michael Shy
Sickle Cell Trait, Sickle Cell Disease
Blood Sampling for Research Related to Sickle Cell Disease
This study will collect representative blood samples from healthy children and adults and from children and adults who have unique red blood cell features that are related to sickle cell disease.
- Conditions
- Sickle Cell Trait, Sickle Cell Disease, Sickle Cell Anemia
- Trial name
- NCT00542230
- Where
- United States
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Mood Disorders, Anxiety Disorders
Development of Magnetic Resonance Imaging Techniques for Studying Mood and Anxiety Disorders
This study is intended to help develop new MRI imaging techniques for studying mood and anxiety disorders. Researchers believe that depression and anxiety disorders may cause structural and functional changes in the brain.
- Trial name
- NCT00397111
- Testing
- 7T Magnetic Resonance Imaging scanner
- Where
- United States
- Volunteers
- 390 people, healthy volunteers welcome
- Sponsor
- National Institute of Mental Health (NIMH)
Stomatognatic, Tooth Diseases
Oral Specimen and Data Acquisition Study of Subjects Requiring Third Molar Removal
Background: The third molars (wisdom teeth) normally grow in during late adolescence or early adulthood. Many people need or choose to have these teeth removed with oral surgery.
- Conditions
- Stomatognatic, Tooth Diseases, Diseases, Tooth
- Trial name
- NCT01805869
- Where
- United States
- Volunteers
- 3,000 people, healthy volunteers welcome
- Sponsor
- National Institute of Dental and Craniofacial Research (NIDCR)
HIV, Pregnancy
Evaluating the Healthy Families PrEP Program for Women at Risk for HIV
Study investigators developed and piloted a counselling intervention, Healthy Families-PrEP, that supports women to use HIV prevention strategies while trying for and during pregnancy.
- Conditions
- HIV, Pregnancy, Pre-Exposure Prophylaxis of HIV Infection
- Trial name
- HFPT (NCT06746675)
- Testing
- Healthy Families PrEP Counselling Intervention
- Where
- Uganda
- Volunteers
- 660 people, healthy volunteers welcome
- Sponsor
- Yale University
Hypertension, Diabetes
Genetics of Type 2 Diabetes in West Africans
Background: Type 2 diabetes (T2D) and associated complications are major contributors to the global disease burden. T2D is already a major health threat in populations in developed countries and is rapidly taking hold in the…
- Trial name
- NCT00837122
- Where
- 5 sites in Ghana, Nigeria
- Volunteers
- 7,418 people, healthy volunteers welcome
- Sponsor
- National Human Genome Research Institute (NHGRI)
Healthy Adult
A Single Ascending Dose Study of DTI-117 Given Intramuscularly in Healthy Participants.
This is a single ascending dose, double-blind, placebo-controlled, randomized evaluation of the safety, tolerability, and pharmacokinetics of DTI-117 in healthy volunteers.
- Trial name
- NCT07882472
- Testing
- DTI-117
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Dignify Therapeutics
Leukocyte Disorders, Respiratory Tract Diseases
Collection of Lung Fluid and Tissue Samples for Research
This study will collect fluid and tissue specimens from the lungs and nose of healthy people and people with a history of lung infections.
- Conditions
- Leukocyte Disorders, Respiratory Tract Diseases, Bronchoscopy
- Trial name
- NCT00471250
- Where
- United States
- Volunteers
- 550 people, healthy volunteers welcome
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Urinary Catheterization, Urinary Catheterization Skills
Comparison of Three Teaching Methods for Urinary Catheterization in Nursing Students
Research Questions 1. Do total learning motivation and sub-dimension scores (attention-relevance, confidence-satisfaction) differ significantly among nursing students using different instructional materials for urinary…
- Conditions
- Urinary Catheterization, Urinary Catheterization Skills, Nursing Students, Learning Methodology
- Trial name
- NCT07893990
- Testing
- Training on performing urinary catheterization using simulation
- Where
- Turkey (Türkiye)
- Volunteers
- 112 people, healthy volunteers welcome
- Sponsor
- Cukurova University
Hepatitis D, Hepatitis C
Evaluation of Patients With Liver Disease
The proposed study aims to evaluate, investigate, and follow-up patients suffering from acute and chronic liver disease. The study will focus on understanding diseases affecting the liver.
- Conditions
- Hepatitis D, Hepatitis C, Hepatitis B, Liver Disease
- Trial name
- NCT00001971
- Where
- United States
- Volunteers
- 8,050 people, healthy volunteers welcome
- Sponsor
- National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Stress
Stress Modulation and Dynamic Balance
This three-arm, parallel-group, randomized controlled trial (RCT) investigates whether dual-task therapeutic exercises (dynamic balance + cognitive task) improve perceived stress and dynamic balance in 72 healthy university…
- Trial name
- NCT07571369
- Testing
- Dynamic balance exercises, Control group, Dual task exercises
- Where
- Egypt
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Kafrelsheikh University
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