Clinical trials: ABDOMINAL AORTIC ANEURYSMS
Abdominal Aortic Aneurysm (AAA), Thoracic Aortic Aneurysm (TAA)
Overlay of 3D Scans on Live Fluoroscopy for Endovascular Procedures in the Hybrid OR
As endovascular procedures become more complex, there is a growing need for 3D image overlay to assist with device guidance and placement.
- Conditions
- Abdominal Aortic Aneurysm (AAA), Thoracic Aortic Aneurysm (TAA), Carotid Stenosis, Visceral Artery Aneurysm
- Trial name
- NCT01480206
- Testing
- Endovascular Aortic Repair (EVAR)
- Where
- United States
- Volunteers
- 58 people
- Sponsor
- Philips Clinical & Medical Affairs Global
Abdominal Aortic Aneurysm, Endovascular Procedures
Standardization of Physician-Modified Stent Grafts for Abdominal Aortic Aneurysms
This study explores the use of physician-modified stent grafts (PMSGs) for treating abdominal aortic aneurysms that are unsuitable for open surgery or standard endovascular grafts.
- Conditions
- Abdominal Aortic Aneurysm, Endovascular Procedures, Stents, Vascular Surgical Procedures
- Trial name
- RESTORE (NCT06585215)
- Where
- Switzerland
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Ente Ospedaliero Cantonale, Bellinzona
Abdominal Aortic Aneurysm, Abdominal Aortic Aneurysm Without Rupture
IOPS Technology During Cannnulation of Contralateral Limb in EVAR
Short-term results are favorable for EndoVascular Aneurysm Repair (EVAR) compared to open surgery. One of the major drawbacks to this shift is the need for fluoroscopy and contrast dyes to visualise endovascular devices.
- Conditions
- Abdominal Aortic Aneurysm, Abdominal Aortic Aneurysm Without Rupture, Radiation Exposure
- Trial name
- IOPS (NCT06570785)
- Testing
- Intra-Operative Positioning System (IOPS), Conventional group
- Where
- Serbia
- Volunteers
- 80 people
- Sponsor
- Clinical Centre of Serbia
Abdominal Aortic Aneurysm
Contrast Enhanced Ultrasound Endoleak Identification and Classification
Surgery for abdominal aortic pathology usually occurs in the setting of advanced cardiovascular disease. The repair can be relatively simple or complex with multiple steps including open repair, placing a stent with a catheter…
- Trial name
- NCT04615559
- Testing
- Contrast enhanced ultrasound
- Where
- United States
- Sponsor
- University of Southern California
Abdominal Aortic Aneurysm
Molecular Imaging of the Underlying Mechanism of Vessel Wall Inflammation Using Positron Emission Tomography (PET/CT)
This research study is being conducted to test how an imaging drug called 64Cu-DOTA-ECL1i can be used to image an abdominal aortic aneurysm.
- Trial name
- NCT07548099
- Testing
- 64Cu-DOTA-ECL1i
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Aortic Aneurysm, Thoracic, Aortic Aneurysm, Abdominal
Development of Ultra-Low Dose CT Based Screening for Aortic Aneurysms
The primary objective of this research project is development and validation of a new, non-contrast gated aortic (NCGA) computer tomography scan algorithm for screening of aortic aneurysm in the chest and abdomen in at risk…
- Trial name
- NCT03479164
- Testing
- Ultra Low-Dose CT
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of Minnesota
Coronary Artery Disease, Abdominal Aortic Aneurysm
Abdominal Aortic Aneurysm Screening Before Coronary Artery Bypass Surgery
Coronary artery disease (CAD) and abdominal aortic aneurysm (AAA) are two separate entities with common risk factors such as hypertension, advanced age, male sex.
- Trial name
- NCT05449509
- Testing
- Abdominal aortic Duplex ultrasound
- Where
- Turkey (Türkiye)
- Volunteers
- 170 people
- Sponsor
- Başakşehir Çam & Sakura City Hospital
AAA - Abdominal Aortic Aneurysm
A Study of the Safety of Targeted AAA Screening
This study is a data linkage project within which we aim to model the impact on the NHS AAA Screening programme of a targeted approach to screening by targeting men who smoke.
- Trial name
- NCT03365050
- Testing
- No Intervention Given
- Where
- United Kingdom
- Volunteers
- 1,000,000 people, healthy volunteers welcome
- Sponsor
- University of Leicester
Abdominal Aortic Aneurysm
Detecting Abdominal Aortic Aneurysms in First Degree Relatives (Adult Offsprings) to AAA Patients (DAAAD)
The 8-12 fold higher risk for sisters and brothers of patients with Abdominal Aortic Aneurysms (AAA) to develop AAA compared to persons in the population is well known in the scientific community.
- Trial name
- DAAAD (NCT04623268)
- Testing
- Ultrasound and questionnaire
- Where
- Sweden
- Volunteers
- 1,500 people, healthy volunteers welcome
- Sponsor
- Karolinska University Hospital
Abdominal Aortic Aneurysms, Pseudoexfoliation Syndrome
Abdominal Aortic Aneurysms and Pseudoexfoliation Syndrome
Conflicting results have been reported concerning the association of pseudoexfoliation syndrome (PXF) and abdominal aortic aneurysms (AAA). Schumacher et al.
- Conditions
- Abdominal Aortic Aneurysms, Pseudoexfoliation Syndrome, Hypertension
- Trial name
- NCT00546013
- Where
- France
- Volunteers
- 208 people
- Sponsor
- European Georges Pompidou Hospital
Breast Cancer, Bowel Cancer
EQUITA - A Feasibility Trial of a Faith-placed Intervention to Increase Screening Uptake in Black Adults
The goal of this randomised feasibility trial is to examine feasibility and acceptability of a co-produced and faith-placed intervention to increase uptake of breast, cervical, bowel, and abdominal aortic aneurysm (AAA) screening…
- Conditions
- Breast Cancer, Bowel Cancer, Cervical Cancer, Abdominal Aortic Aneurysm
- Trial name
- EQUITA (NCT06981182)
- Testing
- Faith-placed intervention to promote breast, cervical, bowel, and AAA screening uptake in Black communities.
- Where
- 3 sites in United Kingdom
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- University of Sunderland
Symptomatic Non-ruptured Abdominal Aortic Aneurysms
Investigating Practice Patterns in Symptomatic Non-ruptured Abdominal Aortic Aneurysms (AAA) in Europe
Symptomatic non-ruptured abdominal aortic aneurysms (snrAAA) remain a clinical challenge due to limited evidence and heterogeneous definitions and management strategies.
- Trial name
- DETHINE (NCT07184723)
- Where
- Austria
- Volunteers
- 130 people
- Sponsor
- Wilhelminenspital Vienna
Aortic Aneurysm, Abdominal, Aortic Diseases
Haemodynamic Response to Aortic Surgery
Open elective abdominal aortic surgery is a high risk procedure involving clamping of the aorta. Indications include abdominal aortic aneurysm (AAA) or aortic occlusive disease (AOD) causing lower limb ischaemia.
- Conditions
- Aortic Aneurysm, Abdominal, Aortic Diseases, Acute Kidney Injury
- Trial name
- NCT01704391
- Where
- Denmark
- Volunteers
- 18 people
- Sponsor
- Sygehus Lillebaelt
Bowel Cancer Screening
Using Patient Navigation to Promote Bowel Screening in AAA Attendees.
The goal of this single-arm, multi-centre feasibility study is to assess the efficacy, feasibility and acceptability of implementing patient navigation across Abdominal Aortic Aneurysm (AAA) screening services in England to…
- Trial name
- TET BETA (NCT07721740)
- Testing
- Patient Navigation conversation
- Where
- United Kingdom
- Volunteers
- 4,190 people, healthy volunteers welcome
- Sponsor
- University of Surrey
Abdominal Aortic Aneurysms
Screening for Thoracic Aortic Aneurysm Among a Cohort of Patients With a Degenerative Abdominal Aortic Aneurysm
Many publications deal with the natural history of aortic aneurysms in literature. Except for connective tissue disorders as Marfan or Loeys-Dietz syndrome, aortic aneurysms are a complex multifactorial disease with genetic and…
- Trial name
- NCT01599533
- Testing
- blood samples
- Where
- France
- Volunteers
- 345 people
- Sponsor
- Assistance Publique Hopitaux De Marseille
Abdominal Aortic Aneurysm, Abdominal Aortic Stenosis
Effectiveness of TAP (Transversus Abdominis Plane) Block for Abdominal Aortic Surgery
The goal of this study is to learn about the effectiveness of TAP block for pain relief after vascular surgery on the abdominal aorta.
- Conditions
- Abdominal Aortic Aneurysm, Abdominal Aortic Stenosis, Syndrome, Leriche
- Trial name
- NCT05860452
- Testing
- ropivacaine, normal saline
- Where
- Slovenia
- Volunteers
- 30 people
- Sponsor
- University Medical Centre Ljubljana
Aortic Aneurysm, Abdominal
The Effect of Abdominal Aortic Aneurysm Screening on Mortality in Asian Population
Abdominal aortic aneurysm(AAA) occurs when the infrarenal aorta expands to a maximal diameter of 3.0cm or greater. Although AAA may asymptomatic for many years, almost one third eventually rupture if left untreated.
- Trial name
- NCT01205945
- Where
- South Korea
- Volunteers
- 12,000 people
- Sponsor
- Kyunghee University Medical Center
Abdominal Aortic Aneurysm, Carotid Atherosclerosis
Preconditioning Shields Against Vascular Events in Surgery
Major vascular surgery involves operations to repair swollen blood vessels, clear debris from blocked arteries or bypass blocked blood vessels.
- Conditions
- Abdominal Aortic Aneurysm, Carotid Atherosclerosis, Critical Lower Limb Ischaemia
- Trial name
- SAVES-F (NCT02097186)
- Testing
- Remote ischaemic preconditioning
- Where
- 6 sites in Ireland
- Volunteers
- 400 people
- Sponsor
- Mid Western Regional Hospital, Ireland
Aortic Aneurysm, Abdominal
An European Union (EU) Post-Approval Registry of the TREO® Stent-Graft
This is an EU sponsored trial and independent of the US trial registered under Clinicaltrials.gov ID NCT02009644. The purpose of this registry is to gather clinical data on the safety and performance of the TREO Stent-Graft in…
- Trial name
- NCT03187522
- Testing
- TREO Stent-Graft System
- Where
- 16 sites in Belgium, Germany and 5 more
- Volunteers
- 174 people
- Sponsor
- Bolton Medical
Thoracoabdominal Aortic Aneurysm
Visceral Manifold Study for the Repair of Thoracoabdominal Aortic Aneurysms
The primary objective of the clinical investigation is to assess the use of the the Visceral Manifold Thoracoabdominal Aortic Aneurysms (VTAAA) stent graft system to repair thoracoabdominal aortic aneurysms in patients having…
- Trial name
- NCT03113383
- Testing
- Thoracoabdominal Aortic Aneurysm Repair
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- Vanderbilt University Medical Center