Clinical trials: ACL Injury
Anterior Cruciate Ligament Injury, Anterior Cruciate Ligament Reconstruction Rehabilitation
Eccentric Phase Biomechanics of the Countermovement Jump After Anterior Cruciate Ligament Reconstruction
Purpose: This study aims to better understand how force is produced during a vertical jump in individuals approximately six months after anterior cruciate ligament reconstruction compared with healthy individuals.
- Trial name
- DECAL (NCT07448064)
- Testing
- Countermovement Jump Force Platform Assessment, Isokinetic Test
- Where
- Switzerland
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Haute Ecole ARC Sante
Anterior Cruciate Ligament Injury
Effect of Resistance Training on Jump Landing Mechanics in Young Female Athletes
The purpose of this study is to determine if jump landing mechanics in young female athletes can be improved with a resistance training intervention.
- Trial name
- NCT02043275
- Testing
- Leg training, Arm training
- Where
- Canada
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Manitoba
Anterior Cruciate Ligament Rupture
Anterior Cruciate Ligament Radiology Follow-up Study
Following recent advances in the understanding of successful anterior cruciate ligament (ACL) reconstruction, three important factors have been identified: femoral tunnel positioning, femoral tunnel aperture shape, and native…
- Trial name
- NCT02816606
- Testing
- Flexible reamers, 70-degree arthroscope
- Where
- United Kingdom
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Royal Devon and Exeter NHS Foundation Trust
ACL Injury, Rehabilitation After ACL Reconstruction
Functional Outcomes of an Accelerated Rehabilitation Protocol for ACL Reconstruction in Amateur Athletes
The main goal of a rehabilitation program after an ACL reconstruction is to regain mobility and muscle function and ultimately to return to sports participation.
- Conditions
- ACL Injury, Rehabilitation After ACL Reconstruction, Accelerated Protocol
- Trial name
- ACL (NCT05716529)
- Testing
- rehabilitation protocol
- Where
- Egypt
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Delta University for Science and Technology
ACL Tear
Effects of Blood Flow Restriction Rehabilitation After Anterior Cruciate Ligament Reconstruction
The study is a prospective randomized control trial consisting of subjects requiring ACL reconstruction with BTB autograft. Subjects were randomly divided into two groups following their inclusion in the study.
- Trial name
- NCT04484961
- Testing
- Blood flow restriction (BFR)
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- The Methodist Hospital Research Institute
Anterior Cruciate Ligament Injuries
Muscle Architecture and Anterior Cruciate Ligament
The aim of this study is to examine the effects of plyometric training on biceps femoris longus (BFl) and vastus lateralis (VL) muscle architecture in individuals with anterior cruciate ligament reconstruction (ACLR).
- Trial name
- NCT04690127
- Testing
- Plyometric Exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
ACL Injury, Postoperative Pain
Ketorolac as an Adjuvant Agent for Postoperative Pain Control Following Arthroscopic ACL Surgery
1. The investigators aim to examine the use of IV and oral ketorolac as an adjunctive agent to the standard of care pain protocol for postoperative pain control following ACL reconstruction surgery. 2.
- Trial name
- NCT04246554
- Testing
- Ketorolac, Oxycodone-Acetaminophen
- Where
- United States
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- University Hospitals Cleveland Medical Center
Anterior Cruciate Ligament Injuries, ACL
Blood Flow Restriction Following ACLR
The purpose of this study is to evaluate the the ability of BFR to reduce muscle loss and improve strength after ACL reconstruction.
- Conditions
- Anterior Cruciate Ligament Injuries, ACL, Physical Therapy
- Trial name
- NCT04086030
- Testing
- Blood Flow Restriction Training
- Volunteers
- healthy volunteers welcome
- Sponsor
- Rush University Medical Center
Anterior Cruciate Ligament Injuries
Cartilage Injury and Remodeling After ACL Rupture and Reconstruction: Functional Imaging and Biomarkers
The proposed study will establish novel relationships between intra-articular MSC recruitment, synovial inflammation, biomarkers of cartilage degeneration and joint inflammation, clinical patient factors, and downstream…
- Trial name
- NCT04970706
- Testing
- ACL reconstruction
- Where
- China
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- Peking University Third Hospital
Anterior Cruciate Ligament Rupture
Evaluation of Tibial and Femoral Tunnel Position After Arthroscopic Reconstruction of the Anterior Cruciate Ligament
The purpose of this study is to evaluate the accuracy of tunnel positions in anterior cruciate ligament reconstruction
- Trial name
- NCT01267435
- Testing
- Anterior cruciate ligament reconstruction
- Where
- Iran
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Isfahan University of Medical Sciences
Anterior Cruciate Ligament Rupture
RCT of PEP Program to Reduce ACL Injuries in Female Collegiate Soccer Players
This research study involves implementing and evaluating a physical training program specifically designed to reduce the risk of ligamentous knee injuries in female soccer players by incorporating proven neuromuscular and…
- Trial name
- NCT00140270
- Testing
- PEP program
- Volunteers
- 4,000 people, healthy volunteers welcome
- Sponsor
- Centers for Disease Control and Prevention
Anterior Cruciate Ligament Injuries, Anterior Cruciate Ligament Rupture
Investigation of the Effects of Proprioceptive Exercises After Anterior Cruciate Ligament Surgery
The aim of this study is to investigate the effects of proprioceptive exercises on balance, kinesiophobia, and functionality after anterior cruciate ligament surgery.
- Trial name
- NCT07333092
- Testing
- control, exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Uskudar University
Anterior Cruciate Ligament Injury, Knee Injuries
Bone Tunnel Widening Following ACL Reconstruction
Hypothesis 1: There is less tunnel-widening with bone-patella tendon-bone graft compared with the hamstring graft when the same fixation method is used.
- Trial name
- NCT00198042
- Testing
- Surgical reconstruction of the ACL
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Hospital for Special Surgery, New York
Sports Injury, Orthopedic Disorder
Training of Falling Techniques on Landing Mechanics
The overall purpose of this study is to quantify the effect and retention of one-week training of falling techniques on landing biomechanics associated with anterior cruciate ligament (ACL) loading compared to soft-landing…
- Conditions
- Sports Injury, Orthopedic Disorder, Knee Injuries, Anterior Cruciate Ligament Injuries
- Trial name
- NCT04768088
- Testing
- Falling Training
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Wyoming
Anterior Cruciate Ligament Injuries
Individualized Anterior Cruciate Ligament Versus Conventional Reconstruction
A randomised prospective control trial comparing the efficiency of a more individualized approach in ACL reconstruction with the help of neuromuscular computer models with traditional ACL reconstruction practices.
- Trial name
- IACLR (NCT04366362)
- Testing
- Individualised ACL reconstruction, Conventional ACL reconstruction
- Where
- Greece
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Larissa University Hospital
Anterior Cruciate Ligament Rupture
Return to Play After ACL Reconstruction With Bone Marrow Aspirate, DBM, and an Internal Brace
The Investigators are studying the effect of an ACL reconstruction on return to play by capturing outcome measures and biomechanics information.
- Trial name
- NCT06294314
- Testing
- Fertilized ACL
- Where
- United States
- Volunteers
- 450 people, healthy volunteers welcome
- Sponsor
- Marshall University
Anterior Cruciate Ligament Rupture
Return to Work and Functional Results of French Soldiers After Anterior Cruciate Ligament Reconstruction
The return to work in the military population after surgical reconstruction of the anterior cruciate ligament (ACL) has been poorly investigated within the French armed forces.
- Trial name
- NCT04668677
- Testing
- On-line questionnaire
- Where
- France
- Volunteers
- 222 people, healthy volunteers welcome
- Sponsor
- Direction Centrale du Service de Santé des Armées
Anterior Cruciate Ligament Injuries, Quadriceps Muscle Atrophy
The Effects of Whole-body Vibration on Increasing Quadriceps Strength in Patients With ACL Ruptures
Introduction: Approximately 35% patients can not return to sports after anterior cruciate ligament reconstruction(ACLR). Persistent quadriceps weakness is a factor that prevents patients return to sports.
- Trial name
- NCT04988828
- Testing
- Whole body vibration
- Where
- Hong Kong
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Chinese University of Hong Kong
ACL - Anterior Cruciate Ligament Rupture
Bio ACL Reconstruction Amnion Collagen Matrix Wrap and Stem Cells
Collagen based -membrane derived from amniotic tissue can be used to help reestablish the natural synovial lining of the reconstructed ACL, in effect acting as both a barrier from the synovial fluid and as a scaffold to contain…
- Trial name
- BioACLRCT (NCT03294759)
- Testing
- Bio ACL, Control
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Andrews Research & Education Foundation
Articular Cartilage Degeneration
MechSens - Dose-response Relationship of in Vivo Ambulatory Load and Mechanosensitive Cartilage Biomarkers
This study is to investigate the effects of age, tissue status and the presence of inflammation on the in vivo dose-response relationship of ambulatory load and mechanosensitive blood markers of articular cartilage.
- Trial name
- MechSens (NCT04128566)
- Testing
- walking stress test
- Where
- Switzerland
- Volunteers
- 87 people, healthy volunteers welcome
- Sponsor
- University Hospital, Basel, Switzerland