Clinical trials: ACL Reconstruction
ACL Reconstruction, Tenodesis
Clinical and Biomechanical Outcomes of Anterior Cruciate Ligament (ACL) Reconstruction Associated With Lateral Extra-articular Tenodesis (LET)
The anterior cruciate ligament (ACL) is one of the main stabilizers of the knee joint, and its injury is among the most common soft tissue injuries of the knee.
- Conditions
- ACL Reconstruction, Tenodesis, ACL Injuries
- Trial name
- LETOTT (NCT07049484)
- Where
- Italy
- Volunteers
- 51 people
- Sponsor
- Stefano Zaffagnini
ACL Reconstruction
Psychological and Physiological Parameters for Return-to-sport After ACL Reconstruction
Injuries to the anterior cruciate ligament are common and are usually treated with reconstruction and subsequent rehabilitation. Many people succeed in return to sport (RTS), but not to the original level.
- Trial name
- ACL-RTS (NCT07259083)
- Where
- Austria
- Volunteers
- 30 people
- Sponsor
- Johannes Kepler University of Linz
Anterior Cruciate Ligament Reconstruction Rehabilitation, Strength Outcomes
Effect of Graft Type on Knee Muscle Strength After ACL Reconstruction
This prospective observational study will compare recovery after anterior cruciate ligament reconstruction using quadriceps tendon autograft or hamstring tendon autograft.
- Conditions
- Anterior Cruciate Ligament Reconstruction Rehabilitation, Strength Outcomes, Anterior Cruciate Ligament (ACL) Reconstruction Surgery
- Trial name
- GRAFT-ACL (NCT07523854)
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Hacettepe University
ACL Reconstruction, ACL Injury
Validity of the SHD-LESS Scale After ACL Reconstruction
After anterior cruciate ligament reconstruction (ACL-R), Single Hop for Distance (SHD) performance aids in decision-making, particularly for return-to-sport assessments.
- Trial name
- ACL-LESS (NCT06829849)
- Testing
- Landing error assessment during a SHD task using the SHD-LESS scale
- Where
- France
- Volunteers
- 60 people
- Sponsor
- University Hospital, Caen
Anterior Cruciate Ligament (ACL), Reconstruction
Study of the Isometry of the Anterior Cruciate Ligament From the Center of the Native MRI Insertion Reported on Dynamic Scanner
In anterior cruciate ligament (ACL) reconstruction, navigation and robotic assistance now provide the possibility of precise positioning of the tunnels.
- Conditions
- Anterior Cruciate Ligament (ACL), Reconstruction, Software
- Trial name
- PLANISOLCA (NCT06996145)
- Testing
- dynamic 4D scanner
- Where
- France
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire, Amiens
Anterior Cruciate Ligament (ACL) Reconstruction, Anterior Cruciate Ligament Injury
Comparison of Bone-patellar Tendon-bone and Patellar Tendon-bone Grafts in ACL Reconstruction
The purpose of this randomized study is to compare donor site morbidity and clinical and functional outcomes of both surgery techniques (bone-patellar tendon-bone (BPTB) graft versus bone-patellar tendon without patellar bone…
- Trial name
- NCT07475351
- Testing
- Bone-Patellar tendon-Bone, Patellar tendon-Bone
- Where
- Spain
- Volunteers
- 110 people
- Sponsor
- Universidad de Granada
ACL Reconstruction, ACL Surgery
Post Operative Use of Neuromuscular Electrical Stimulation (NMES) Device for ACLR Patients
This study is being conducted to learn about how neuromuscular electrical stimulation (NMES) in addition to standard of care aids in the recovery of muscle strength in patients undergoing ACLR procedure.
- Conditions
- ACL Reconstruction, ACL Surgery, ACL Injury, Electrotherapy
- Trial name
- NCT07171346
- Testing
- Zynex NexWave Electrotherapy Device
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- University of Kansas Medical Center
ACL Reconstruction
Readiness Outcomes Affecting Return to Sport 3.0
The primary aim is to determine if MST will improve coping skills in young athletes returning to sport after ACLR as measured by ACSI-28.
- Trial name
- ROAR 3 (NCT07476430)
- Testing
- Mental Skills Training (MST)
- Where
- United States
- Volunteers
- 130 people
- Sponsor
- Boston Children's Hospital
ACL Reconstruction, Intraarticular Injection
Comparison of Functional Outcomes Following Arthroscopic ACL Reconstruction With Peroneus Longus Autograft With and Without Intra-articular Platelet-Rich Plasma Injection.
This prospective RCT investigates if a single 4 ml intra-articular PRP injection improves knee function after ACL reconstruction using peroneus longus autograft.
- Conditions
- ACL Reconstruction, Intraarticular Injection, PRP
- Trial name
- NCT07470359
- Testing
- PRP injection
- Where
- Pakistan
- Volunteers
- 60 people
- Sponsor
- Lahore General Hospital
Rehabilitation, ACL Reconstruction
Neuromuscular Intervention Targeted to Mechanisms of ACL Load in Female Athletes
The overall goal of this project is to reduce risk of second anterior cruciate ligament (ACL) injury in vulnerable populations (active athletes between 14 = 24 years old) through the identification of relative injury risk groups…
- Trial name
- NCT03190889
- Testing
- HOME, TNMT
- Where
- 4 sites in United States
- Volunteers
- 150 people
- Sponsor
- Mayo Clinic
ACL Reconstruction
Effect of Internal Brace on Outcomes Following ACL Reconstruction With BTB Autograft
The purpose of this study is to assess Anterior Cruciate Ligament (ACL) healing through analyzing clinical, radiographic, functional and patient-reported outcomes following ACL reconstruction with bone-tendon-bone autograft with…
- Trial name
- NCT06542705
- Testing
- Arthrex Internal Brace, ACL Reconstruction
- Where
- United States
- Volunteers
- 90 people
- Sponsor
- NYU Langone Health
Osteoarthritis (OA) of the Knee, ACL Reconstruction
Personalized Digital Training Intervention to Reduce Inflammation by Correcting Pathological Movement Patterns in Pre-stage Knee Osteoarthritis After Anterior Cruciate Ligament Reconstruction
Osteoarthritis (OA) is a condition that causes pain and stiffness in the joints, often due to injuries like torn ligaments. Even after surgery, these injuries can lead to long-term joint problems.
- Trial name
- PROTO-WP4 (NCT06596824)
- Testing
- Training intervention
- Where
- 2 sites in Germany
- Volunteers
- 60 people
- Sponsor
- Charite University, Berlin, Germany
Anterior Cruciate Ligament (ACL) Reconstruction Surgery
KRONOS Versus Breg T-Scope Post-operative Knee Braces Following Anterior Cruciate Ligament (ACL) Reconstruction
The purpose of this study is to evaluate how well the KRONOS postoperative knee brace reduces pain and enhances recovery compared with the standard Breg T-scope hinged brace following anterior cruciate ligament (ACL)…
- Trial name
- NCT07090616
- Testing
- Arm 1-Kronos brace, Arm 2-Breg T-Scope brace
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Rush University Medical Center
ACL Reconstruction, ACL Repair
Isokinetic Exercise Combined With Blood Flow Restriction: High-Load Vs Low-Load Training
The goal of this clinical trial is to see which type of strengthening exercise with a tight band (blood flow restriction) helps people recover better after ACL reconstruction.
- Trial name
- NCT07384780
- Testing
- High Load Isokinetic Training with Blood Flow Restriction, Low Load Isokinetic Training with Blood Flow Restriction
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Gulf Medical University
ACL Reconstruction, Hemarthrosis
Study the Anti-inflammatory Effect of Tranexamic Acid When Used in Anterior Cruciate Ligament Reconstruction.
Tranexamic acid (TXA) is widely used in orthopedic surgery to reduce perioperative blood loss, particularly in total hip and knee arthroplasty, due to its antifibrinolytic mechanism, low cost, broad availability, and established…
- Trial name
- TXA (NCT07332910)
- Testing
- Tranexamic Acid (TXA)
- Where
- Belgium
- Volunteers
- 60 people
- Sponsor
- Chirec
ACL Reconstruction
Application of Multiple Vertical Jump Tests in Return-to-Play Assessment for Anterior Cruciate Ligament Reconstruction Athletes
Anterior cruciate ligament (ACL) injury is a common sports-related injury, particularly in sports that require extensive jumping and cutting movements.
- Trial name
- RTP-VJ (NCT07297511)
- Where
- Taiwan
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Kaohsiung Medical University
ACL Reconstruction, Extracorpereal Shock Wave Therapy
Efficacy of Focused Extracorporeal Shock Wave Therapy After Anterior Cruciate Ligament Reconstruction
The aim of this clinical trial is to determine the effectiveness of fESWT in rehabilitation after ACL reconstruction. The main questions it aims to answer are: Is fESWT applied in addition to conventional physiotherapy effective…
- Trial name
- NCT06688344
- Testing
- fESWT, Conventional Physiotherapy
- Where
- Turkey (Türkiye)
- Volunteers
- 32 people
- Sponsor
- Berivan Beril Kılıç
ACL Injury, ACL Reconstruction
Study to Use Oral Losartan to Decrease the Risk of Postoperative Scarring Following (ACL) Reconstruction
The purpose of this study to investigate the effect of using losartan (a blood pressure lowering drug with anti-scarring properties) on preventing primary postoperative arthrofibrosis (formation of abnormal scar tissue) in the…
- Conditions
- ACL Injury, ACL Reconstruction, Scar Formation
- Trial name
- NCT07135687
- Testing
- Losartan
- Where
- United States
- Volunteers
- 144 people
- Sponsor
- Rush University Medical Center
Anterior Cruciate Ligament (ACL) Reconstruction, Preoperative Rehabilitation
VR-Based Preoperative Rehabilitation Program for Patients Undergoing Anterior Cruciate Ligament (ACL) Reconstruction
Between April 2, 2024, and October 1, 2024, a study will be conducted at the Department of Orthopedics in the First Affiliated Hospital of Shantou University Medical College involving 120 patients who will undergo anterior…
- Trial name
- NCT06347523
- Testing
- The VR-based preoperative rehabilitation program;, standard nursing care,
- Where
- China
- Volunteers
- 100 people
- Sponsor
- First Affiliated Hospital of Shantou University Medical College
ACL Surgery, ACL Injuries
Developing and Validating the Risk-taking Intention and Sport Engagement After ACL Reconstruction (RISE-ACL) Scale
Psychological factors play a critical role in recovery following anterior cruciate ligament (ACL) reconstruction. While tools such as the ACL - Return to Sport after Injury (ACL-RSI) focus on psychological readiness, emphasizing…
- Conditions
- ACL Surgery, ACL Injuries, ACL Reconstruction
- Trial name
- RISE-ACL (NCT06748066)
- Testing
- RISE-ACL development, RISE-ACL scale validation
- Where
- France
- Volunteers
- 162 people
- Sponsor
- University Hospital, Caen