Clinical trials: ACL Reconstruction
Joint Infection
Joint Infection Following ACL Reconstruction
This study was conducted to analyze the effect of joint infection on the bone tunnel, graft and articular cartilage following arthroscopic single-bundle anterior cruciate ligament (ACL) reconstruction with autologous hamstring…
- Trial name
- NCT04948281
- Testing
- no intervention
- Where
- China
- Volunteers
- 104 people
- Sponsor
- Peking University Third Hospital
Anterior Cruciate Ligament Injuries
A Study Of Focused Shockwave For Anterior Knee Pain Following Anterior Cruciate Ligament Reconstruction
The purpose of this study is to investigate whether Focused Shockwave (FSW) therapy reduces anterior knee pain following anterior cruciate ligament reconstruction (ACL-R) with bone-patellar tendon-bone (BTB) or quadriceps tendon…
- Trial name
- NCT07580157
- Testing
- Focused Shockwave
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Mayo Clinic
Anterior Cruciate Ligament Reconstruction
Pediatric ACL: Understanding Treatment Options
Pediatric ACL: Understanding Treatment Outcomes (PLUTO) is a multi-center, prospective cohort study. Specific aims of PLUTO are to evaluate the safety and comparative effectiveness of non-operative treatment, as well as four…
- Trial name
- PLUTO (NCT02772770)
- Testing
- Non-operative treatment group will undergo standardized treatment which will include rehabilitation, bracing and certain activity restrictions, Surgical technique: Transphyseal reconstruction, Surgical technique: Partial transphyseal reconstruction
- Where
- 10 sites in United States
- Volunteers
- 765 people, healthy volunteers welcome
- Sponsor
- Boston Children's Hospital
ACL Injury
Association Between Neuromuscular Parameters and Functional Assessment After ACL Reconstruction
The anterior cruciate ligament (ACL) injury is common in athletes aged 18 to 35. ACL reconstruction (ACLR) aims to restore knee stability in the process of returning to sports.
- Trial name
- KASTLAB (NCT06524869)
- Testing
- Isokinetic neuromuscular assessment
- Where
- France
- Volunteers
- 25 people
- Sponsor
- University Hospital, Caen
Anterior Cruciate Ligament Injury, Knee Injuries
Sensory Deficit Following ACL Reconstruction: PRF Pilot Study
Pilot, single-center, non-randomized, parallel-group clinical study designed to assess whether intraoperative application of autologous platelet-rich fibrin (PRF) at the bone-patellar tendon-bone (BPTB) donor site reduces…
- Conditions
- Anterior Cruciate Ligament Injury, Knee Injuries, Sensory Disorders, Bone-Patellar Tendon-Bone Autograft
- Trial name
- PRF-ACL (NCT07257666)
- Testing
- Platelet-rich fibrin (PRF), Standard Closure (Control)
- Where
- Serbia
- Volunteers
- 53 people
- Sponsor
- University of Belgrade
PRP, ACL
Prospective Analysis of Introperative RegenLab PRP and Hyaluronic Acid in Patients With Knee ACL Tear
Purpose: The purpose of this article is to examine the clinical application of PRP and PRP+hyaluronic acid in disorders in the knee.
- Conditions
- PRP, ACL, Hyaluronic Acid
- Trial name
- NCT04586361
- Testing
- RegenLab PRP, hyaluronic acid, normal saline
- Where
- Taiwan
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Kaohsiung Veterans General Hospital.
Anterior Cruciate Ligament (ACL), Reconstruction
Study of the Isometry of the Anterior Cruciate Ligament From the Center of the Native MRI Insertion Reported on Dynamic Scanner
In anterior cruciate ligament (ACL) reconstruction, navigation and robotic assistance now provide the possibility of precise positioning of the tunnels.
- Conditions
- Anterior Cruciate Ligament (ACL), Reconstruction, Software
- Trial name
- PLANISOLCA (NCT06996145)
- Testing
- dynamic 4D scanner
- Where
- France
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire, Amiens
ACL Injury
The Effect of Whole Body Vibration After ACLR
This is a randomised clinical trial to detect the effect of an 8-week whole body vibration training on muscle function and dynamic knee function during single leg squat and single leg hop in patients after anterior cruciate…
- Trial name
- NCT05254054
- Testing
- whole body vibration, Conventional exercise training
- Where
- Hong Kong
- Volunteers
- 50 people
- Sponsor
- Chinese University of Hong Kong
Anterior Cruciate Ligament Injury
ACL SNNAP Trial: ACL Surgery Necessity in Non Acute Patients
The primary objective of this study is to determine in patients with non-acute Anterior Cruciate Ligament Deficiency (ACLD) whether a strategy of non-surgical management [Rehabilitation] (with option for later ACL reconstruction…
- Trial name
- ACL SNNAP (NCT02980367)
- Testing
- Non-Surgical Management (Rehabilitation), Surgical Management (Reconstruction)
- Where
- 32 sites in United Kingdom
- Volunteers
- 320 people
- Sponsor
- University of Oxford
Anterior Cruciate Ligament Rupture
LIBRE (Ligamys, Internal Bracing, REconstruction) Study: Comparing Three Surgery Techniques After an Acute ACL Rupture.
Single-blind, multi-centre, prospective, randomized controlled trial comparing Ligamys Anterior Cruciate Ligament (ACL) repair, Internal Bracing ACL repair and conventional ACL reconstruction for relative clinical efficacy and…
- Trial name
- LIBRE (NCT03441295)
- Testing
- Dynamic Intraligamentary Stabilization, Internal Brace Ligament Augmentation, ACL Reconstruction
- Where
- 3 sites in Belgium
- Volunteers
- 95 people
- Sponsor
- University Hospital, Antwerp
Pain
Comparison Of Effectiveness of Mobilization With Movement (MWM) and Kelternborn Treatment Technique to Increase ROM, Reducing Pain in Patient of ACL Reconstruction
To determine the Comparison Of Effectiveness of Mobilization With Movement (MWM) and Kelternborn Treatment Technique to Increase ROM, Reducing Pain in Patient of ACL Reconstruction
- Trial name
- NCT05873101
- Testing
- Mobilization With Movement (MWM), Kelternborn Treatment Technique
- Where
- Pakistan
- Volunteers
- 22 people
- Sponsor
- Superior University
Anterior Cruciate Ligament Reconstruction
SeriACL™ Device (Gen IB) Trial for Anterior Cruciate Ligament (ACL) Repair
A multi-center single-arm clinical trial is being conducted to evaluate SeriACL device safety and performance during total anterior cruciate ligament (ACL) reconstruction.
- Trial name
- NCT00775892
- Testing
- SeriACL Device ACL Reconstruction
- Where
- 6 sites in Austria, Belgium and 1 more
- Volunteers
- 30 people
- Sponsor
- Serica Technologies, Inc.
Anterior Cruciate Ligament Reconstruction
Adding Modified Visual Feedback Training in Patients Following ACL Reconstruction
The current treatment for the ACL-injured patients usually emphasize on the movement quality through neuromuscular training. The purpose of this study is to (1) design a modified visual feedback training program and (2)…
- Trial name
- NCT03738436
- Testing
- Physical therapy traditional neuromuscular training, NMT, Physical therapy modified visual feedback, MVF
- Where
- Taiwan
- Volunteers
- 40 people
- Sponsor
- China Medical University Hospital
Anterior Cruciate Ligament Reconstruction
Whole Body Vibration in Individuals Submitted to ACL
The purpose of this study is to analyze the immediate effects of two exercises protocols on the whole body vibration, on the strength of the thigh muscles, joint position sense of the knee and balance in individuals submitted to…
- Trial name
- NCT02609971
- Testing
- Vibration at 50 Hz
- Volunteers
- 46 people
- Sponsor
- Universidade Federal do Rio Grande do Norte
Anterior Cruciate Ligament Reconstruction
Tourniquet vs. Dual-flow Arthroscopy Sheath in Anterior Cruciate Ligament (ACL) Reconstruction
This is a prospective randomized study comparing tourniquet use versus a dual-flow arthroscopy sheath in Anterior Cruciate Ligament (ACL) reconstruction surgery.
- Trial name
- RELICA (NCT06819696)
- Testing
- ACL reconstruction with a dual-flow arthroscopy sheath, ACL reconstruction with a thigh tourniquet
- Where
- 3 sites in France
- Volunteers
- 128 people
- Sponsor
- Centre Hospitalier Intercommunal de Toulon La Seyne sur Mer
Pain, Postoperative, Anterior Cruciate Ligament Injuries
IPACK on Early Pain Scores After ACL Reconstruction
The goal of this clinical trial is to learn whether using an anesthetic technique called IPACK block will control pain after ACL reconstruction surgery.
- Conditions
- Pain, Postoperative, Anterior Cruciate Ligament Injuries, Analgesics, Opioid
- Trial name
- NCT05985629
- Testing
- IPACK
- Where
- United States
- Volunteers
- 78 people
- Sponsor
- Loyola University
Anterior Cruciate Ligament Tear, Knee Meniscus Tear
Adductor Canal Block Versus Femoral Block on Pain and Quadriceps Strength
The purpose of this study is to compare the effects of a femoral nerve block vs. an adductor canal block on pain and quadriceps muscle strength for knee arthroscopy surgery.
- Trial name
- NCT05190120
- Testing
- Femoral Nerve Block, Adductor Canal Nerve Block, preoperative Femoral Nerve Block using 20ml of 0.5% ropivacaine
- Where
- United States
- Volunteers
- 132 people
- Sponsor
- University of California, San Francisco
Anterior Cruciate Ligament (ACL) Tear
Conventional Follow-up Versus Mobile App For Post-Operative ACL Reconstruction Patients
Background: Telemedicine is increasingly used to overcome distance between patients and physicians. Preliminary studies suggest that mobile app follow-up care for ACL reconstruction patients is feasible, can avert in-person…
- Trial name
- NCT02942940
- Testing
- mobile app, conventional in-person
- Where
- Canada
- Volunteers
- 32 people
- Sponsor
- University of Toronto Orthopaedic Sports Medicine
ACL Injury, Knee Injuries
Association Between 4-Month Isokinetic Testing Measures and Second Knee Injuries After Primary Anterior Cruciate Ligament Reconstruction
Anterior cruciate ligament (ACL) is a frequent and disabling injury in athletes. Most of the time, ACL reconstruction (ACLR) is consider for regaining function and returning to preinjury sports while reducing the risk of…
- Conditions
- ACL Injury, Knee Injuries, Muscle Weakness
- Trial name
- PREDICT-ACLv2 (NCT05897970)
- Testing
- Return-to-sport (RTS) follow-up
- Where
- France
- Volunteers
- 150 people
- Sponsor
- University Hospital, Caen
Anterior Cruciate Ligament Reconstruction
Effectiveness of Kneehab in Strengthening Quadriceps in Rehabilitation Post Anterior Cruciate Ligament (ACL) Reconstruction
Prospective, controlled, randomized, single blind study in patients undergoing rehabilitation following anterior cruciate ligament reconstruction. 96 patients were randomly assigned to one of three groups.
- Trial name
- NMES (NCT00738010)
- Testing
- Kneehab, Poli-Stim, Control
- Where
- Germany
- Volunteers
- 131 people
- Sponsor
- Bio-Medical Research, Ltd.