Clinical trials: ACL Tear
ACL Tear
Retrospective CT Imaging of BioComposite Interference Screw With BTB
The purpose of this study is to examine the long-term appearance and resorption rate of biocomposite screws used during ACL reconstruction on X-ray and computed tomography (CT).
- Trial name
- NCT02450292
- Testing
- Bioabsorbable screw fixation
- Volunteers
- 5 people
- Sponsor
- State University of New York at Buffalo
ACL - Anterior Cruciate Ligament Deficiency
Comparison of Surgical Repair Versus Functional Treatment in Patients With Proximal ACL Tear
Isolated ruptures of the anterior cruciate ligament (ACL) can be proximal, distal or occur in the middle of the ACL. Treatment of patients with proximal lesions should be graded.
- Trial name
- SUTUFONC (NCT06178484)
- Where
- France
- Volunteers
- 144 people
- Sponsor
- GCS Ramsay Santé pour l'Enseignement et la Recherche
Anterior Cruciate Ligament Rupture
LIBRE (Ligamys, Internal Bracing, REconstruction) Study: Comparing Three Surgery Techniques After an Acute ACL Rupture.
Single-blind, multi-centre, prospective, randomized controlled trial comparing Ligamys Anterior Cruciate Ligament (ACL) repair, Internal Bracing ACL repair and conventional ACL reconstruction for relative clinical efficacy and…
- Trial name
- LIBRE (NCT03441295)
- Testing
- Dynamic Intraligamentary Stabilization, Internal Brace Ligament Augmentation, ACL Reconstruction
- Where
- 3 sites in Belgium
- Volunteers
- 95 people
- Sponsor
- University Hospital, Antwerp
Anterior Cruciate Ligament Rupture, Pain, Postoperative
Effect of LIA on Postoperative Pain Following ACL Reconstruction
An anterior cruciate ligament (ACL) rupture is one of the most common sport injuries, which typically develops after a sudden knee torsion.
- Trial name
- NCT03873077
- Testing
- local infiltration analgesia
- Where
- Belgium
- Volunteers
- 40 people
- Sponsor
- Algemeen Ziekenhuis Maria Middelares
ACL Injury, MRI
Evaluation of Anterior Cruciate Ligament Tears Using Diffusion Tractography
Knees injuries commonly affect the ACL. French current methodology is based on MRI focused on the knee with morphological sequences (T1, DP fat sat) allowing the study of ACL as follows: No lesion / Partial tear / Complete tear.
- Conditions
- ACL Injury, MRI, Tractography
- Trial name
- TRACTOLCA (NCT05806034)
- Testing
- tractography MRI sequence protocol
- Where
- France
- Volunteers
- 30 people
- Sponsor
- Centre Hospitalier Universitaire, Amiens
Anterior Cruciate Ligament Rupture With Ligamentoplasty
Evaluation of the Evolution of Proprioceptive Reweighting Abilities Following Anterior Cruciate Ligament Reconstruction Surgery
Anterior cruciate ligament (ACL) injury is the most common knee injury among athletes who play contact sports involving pivoting.
- Trial name
- ReproEVO (NCT07389850)
- Testing
- ReproEVO intervention
- Where
- 3 sites in France
- Volunteers
- 34 people
- Sponsor
- University Hospital, Brest
Anterior Cruciate Ligament (ACL) Tear
Effects of a Preoperative Cognitive-Behavioral Intervention on Kinesiophobia and Function in Anterior Cruciate Ligament Reconstruction
This study aims to systematically elucidate the integrative effects of psychological rehabilitation on the "brain-psychology-motor" triad in patients with anterior cruciate ligament (ACL) rupture.
- Trial name
- NCT07423767
- Testing
- Cognitive-Behavioral Intervention, Control group
- Where
- 2 sites in China
- Volunteers
- 44 people
- Sponsor
- Peking University Third Hospital
Anterior Cruciate Ligament Injuries, Anterior Cruciate Ligament Rupture
Investigation of the Effects of Proprioceptive Exercises After Anterior Cruciate Ligament Surgery
The aim of this study is to investigate the effects of proprioceptive exercises on balance, kinesiophobia, and functionality after anterior cruciate ligament surgery.
- Trial name
- NCT07333092
- Testing
- control, exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Uskudar University
Rupture of Anterior Cruciate Ligament
Study of Single And Double Bundle Anterior Cruciate Ligament (ACL) Graft Cross-sectional Dimensions
To study the difference between single and double bundle ACL graft cross-sectional dimensions compared with native ACL using postoperative 3-D MRI.
- Trial name
- NCT02834962
- Testing
- single bundle ACL reconstruction, double bundle ACL reconstruction
- Volunteers
- 100 people
- Sponsor
- Peking University Third Hospital
Ligament; Laxity, Knee, Rupture of Anterior Cruciate Ligament
Anterior Cruciate Ligament-reconstruction: Quadriceps Tendon or Hamstrings Tendon? A Prospective Trial
The purpose of this study is to determine whether there is a difference in muscle strength after anterior cruciate ligament comparing 2 surgery technics. Using either autograft hamstrings tendon or a autograft quadriceps tendon.
- Trial name
- NCT02173483
- Testing
- Quadriceps graft
- Where
- Denmark
- Volunteers
- 100 people
- Sponsor
- Aarhus University Hospital
Anterior Cruciate Ligament Injuries, Anterior Cruciate Ligament Rupture
SEQUAR SEmitendinosus vs QUadriceps in Anterior Cruciate Ligament Reconstruction
Randomized control trial comparing two different Anterior Cruciate Ligament (ACL) grafts in Anterior Cruciate Ligament Reconstruction: the semitendinosus hamstrings graft and the quadriceps graft.
- Conditions
- Anterior Cruciate Ligament Injuries, Anterior Cruciate Ligament Rupture, Anterior Cruciate Ligament Tear
- Trial name
- SEQUAR (NCT04295148)
- Testing
- ACL Reconstruction with Semitendinosus graft, ACL Reconstruction with Quadriceps tendon-bone graft
- Where
- Sweden
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Karolinska Institutet
Anterior Cruciate Ligament Rupture
Hamstring Muscle Strength After ACL Hamstring Reconstruction
Anterior Cruciate Ligament (ACL) reconstructions using hamstring grafts can be performed using one or two hamstring grafts, the semitendinosus (ST) tendon only, or both the semitendinosus and gracilis (ST/G) tendon.
- Trial name
- HAMSTRING (NCT05464485)
- Testing
- ACL hamstring reconstructions using semitendinosus (ST) tendon only, ACL hamstring reconstructions using semitendinosus and gracilis (ST/G) tendon
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- Isala
ACL Reconstruction, Meniscus Tears
A Comparison of Outcomes After Anterior Cruciate Ligament (ACL) or Anterior Cruciate Ligament and Meniscus (ACL+Meniscus) Surgery Using Semiconductor Fabric Products
The goal of this clinical trial is to determine the effect of semiconductor sleeves on the treatment of Anterior Cruciate Ligament (ACL) or Anterior Cruciate Ligament and Meniscus (ACL+Meniscus) arthroscopic surgery.
- Conditions
- ACL Reconstruction, Meniscus Tears, Anterior Cruciate Ligament Rupture
- Trial name
- NCT06979804
- Testing
- Semiconducting fabric sleeves, Non-semiconducting fabric sleeves
- Where
- United States
- Volunteers
- 135 people
- Sponsor
- Illinois Center for Orthopaedic Research and Education
ACL Tears
Characterizing Clinical and Biomechanical Contributions to Function Following ACL Reconstruction
Quantify differences in quadriceps function and gait biomechanics in individuals within 2 years of ACL reconstruction compared to a healthy comparison group and establish the feasibility of conducting a progressive strengthening…
- Trial name
- NCT03132987
- Testing
- Progressive strengthening program
- Where
- United States
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- Creighton University
Anterior Cruciate Ligament Rupture
BFRT in Adolescents After ACL Reconstruction
This is an interventional study that will examine effects of blood flow restriction training (BFRT) in adolescents aged 12-18 after anterior cruciate ligament reconstruction surgery (ACLR).
- Trial name
- NCT04390035
- Testing
- Blood Flow Restriction using Delfi Personalized Tourniquet System
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Children's Healthcare of Atlanta
ACL - Anterior Cruciate Ligament Rupture
The Effect of Cognitive-Based Neuromuscular Exercises on Reaction Time, Joint Position Sense, Proprioceptive Force Sense and Balance in Individuals Who Had Anterior Cruciate Ligament Surgery
The aim of this study is to investigate the effects of cognitive-based neuromuscular exercises on increased reaction time, decreased joint position sense, reduced proprioceptive force sense, and balance problems in individuals…
- Trial name
- NCT06755398
- Testing
- Exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 28 people
- Sponsor
- Ertuğrul Demirdel
Hemorrhage Postoperative, Anterior Cruciate Ligament Rupture
Oral Administration of Tranexamic Acid in Anterior Cruciate Ligament Surgery Reduce Postoperative Haemarthrosis
To find superiority relationship between oral and intravenous administration of tranexamic acid on peroperative and postoperative blood loss, haemarthrosis prevalence and improvement functional prognosis in anterior cruciate…
- Conditions
- Hemorrhage Postoperative, Anterior Cruciate Ligament Rupture, Arthroscopy, Total Blood Loss
- Trial name
- NCT04855877
- Testing
- Oral tablet
- Where
- Belgium
- Volunteers
- 104 people
- Sponsor
- University of Liege
Knee Ligament Injury
Performance and Safety of the Polylactic Interference Screw Used in Anterior Cruciate Ligament Reconstructions
The evaluation of the clinical data has demonstrated the conformity of the Polylactic Interference Screw (PIS), with the relevant essential requirements for its use in orthopaedic applications.
- Trial name
- NCT04122677
- Testing
- Anterior Cruciate Ligament Reconstruction
- Where
- France
- Volunteers
- 55 people
- Sponsor
- Biomatlante
Anterior Cruciate Ligament Injury, Anterior Cruciate Ligament Rupture
The BEAR III Trial for Bridge-Enhanced ACL (Anterior Cruciate Ligament) Restoration
Bridge-Enhanced ACL Restoration (BEAR) is a new procedure being developed to treat patients with ACL injuries. In the BEAR procedure, an implant is placed between the torn ends of the ACL and the patient's own blood is added to…
- Trial name
- NCT03348995
- Testing
- Bridge-Enhanced ACL Restoration (BEAR)
- Where
- 11 sites in United States
- Volunteers
- 250 people
- Sponsor
- Miach Orthopaedics
Anterior Cruciate Ligament Tear
Personalized Blood Flow Restriction for Anterior Cruciate Ligament Rehabilitation
This is a cross-sectional study on the use of personalized blood flow restriction during rehabilitation exercises and its effects on biomechanics on people who have had an anterior cruciate ligament reconstruction and healthy…
- Trial name
- NCT04635579
- Testing
- Blood flow restriction
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Washington