Clinical trials: ADHF
Heart Failure, ADHF
Care Coordination to Assess Improvement in Outcomes in Hospital Readmissions
Heart failure is a syndrome that is defined by distinctive clinical, hemodynamic, and neurohormonal findings. HF represents a final common pathway for many different cardiovascular diseases, including coronary disease…
- Conditions
- Heart Failure, ADHF, Acute MI
- Trial name
- COMPASSION (NCT04905160)
- Testing
- COMPASSION Digital Biomarker
- Where
- United States
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Aventyn, Inc.
Heart Failure; With Decompensation
Comparative Effects of Methylprednisolone and Prednisolone on the Risk of Acute Decompensated Heart Failure - An Emulated Target Trial
The investigators aim to emulate a target trial to compare the risk of acute decompensated heart failure in users of methylprednisolone compared to prednisolone.
- Trial name
- NCT06468007
- Testing
- Methylprednisolone Tablet
- Volunteers
- 12,000 people, healthy volunteers welcome
- Sponsor
- Diakonhjemmet Hospital
Heart Failure
Ultra-sound Assisted Management of Heart Failure
The purpose of this study is to evaluate the impact of using hand carried ultrasound measurements of volume status in directing treatment of heart failure patients admitted with acute exacerbation.
- Trial name
- USA-HF (NCT04376424)
- Testing
- Hand Held Ultrasound
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- The University of Texas Medical Branch, Galveston
Acute Decompensated Heart Failure (ADHF)
Comparison of the Effectiveness of Different Diuretic Therapies in the Management of Acute Heart Failure
Acute decompensated heart failure (ADHF) is a clinical syndrome associated with high morbidity and mortality rates. Current guidelines emphasize the importance of oxygenation and diuresis in the management of ADHF.
- Trial name
- NCT07464249
- Testing
- Furosemide Bolus, Furosemide Continuous İnfusion
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Sultan Abdulhamid Han Training and Research Hospital, Istanbul, Turkey
Heart Failure, Congestive
A Method Validation Study for Evaluation of Novel Treatments Limiting Pulmonary Oedema in Cardiac Failure
Transient receptor potential vanilloid 4 (TRPV4) channel blockade may be promising in the treatment of pulmonary oedema and dyspnoea in heart failure (HF) and acute decompensated heart failure (ADHF) patients by re-establishing…
- Trial name
- NCT02135861
- Testing
- DCE-MRI scans, Gadobutrol
- Where
- United Kingdom
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Acute Kidney Injury, Acute Heart Failure
Predictors of Acute Kidney Injury in Patients With Acute Decompensated Heart Failure in Emergency
Acute Decompensated Heart Failure ADHF is one of the leading causes of hospitalization. ADHF is a growing global health problem affecting more than 26 million individuals worldwide Acute Kidney Injury AKI is a common event in the…
- Trial name
- NCT06463964
- Testing
- Serum Creatinine
- Where
- Egypt
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Sohag University
Acute Decompensated Heart Failure
A Study to Evaluate Lung Ultrasound as a Method to Measure Changes in Extravascular Lung Water Induced by Positional Changes (LUPE)
This is an exploratory study to evaluate lung ultrasound as a method for measuring extravascular lung water in stabilized patients during hospitalization for ADHF.
- Trial name
- LUPE (NCT03146754)
- Testing
- Methodology
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Heart Failure
Evaluation of Circulating Levels of Adult Stem Cells in the Peripheral Blood of Patients With Acute Decompensated Heart Failure and Following Stabilization, in Comparison With Healthy Volunteers
Despite advances in medical technology, heart failure remains a major cause of illness on a global scale. Medical research, over recent years, has shown that adult stem cells (as opposed to embryonic stem cells) are present in…
- Trial name
- CIRCSTEM-HF (NCT01027403)
- Where
- Australia
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Monash University
Acute Decompensated Heart Failure, Congestive Heart Failure Compensated
Role of USCOM in Adult Patients With Heart Failure
Objective: The Ultrasonic Cardiac Output Monitor (USCOM) is a non-invasive, quantitative method for measuring and monitoring cardiovascular haemodynamic parameters in patients. The aims of this study are: 1.
- Trial name
- NCT02289508
- Testing
- Ultrasonic cardiac output monitor, Echocardiography
- Where
- China
- Volunteers
- 242 people, healthy volunteers welcome
- Sponsor
- Chinese University of Hong Kong