Clinical trials: AI Agent, active
Mobility Limitations, Community-dwelling Older Adults
Smart Nursing AI Agent for Health Self-Management
This study aims to develop and evaluate a smart nursing AI agent to support health self-management among middle-aged and older patients, and further to examine its effectiveness in home care and health self-management.
- Conditions
- Mobility Limitations, Community-dwelling Older Adults, Middle-aged and Older Adults
- Trial name
- NCT07761663
- Testing
- Smart Nursing AI Agent
- Where
- Taiwan
- Volunteers
- 102 people
- Sponsor
- National Yang Ming Chiao Tung University
Hereditary Cancer Syndromes
Feasibility Study of a Chatbot AI-Driven Preliminary Screening System for Hereditary Cancer Syndromes
This study aims to assess the feasibility of implementing an AI-based hereditary cancer preliminary screening system that has already been developed.
- Trial name
- NCT07901543
- Testing
- Hereditary cancer preliminary screening chatbot
- Where
- Singapore
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- National Cancer Centre, Singapore
Heart Failure, Cardiomyopathies
Multimodal Physiologic State Intelligence Study
The OMNIPHYS study will investigate whether multimodal ultrasound and other routinely collected clinical and physiologic data can be combined with artificial intelligence to characterize changes in a person's physiologic state…
- Conditions
- Heart Failure, Cardiomyopathies, Pulmonary Hypertension, Myocarditis; Acute or Subacute
- Trial name
- OMNIPHYS (NCT07814118)
- Testing
- OMNIPHYS Multimodal Ultrasound Imaging System
- Where
- United States
- Volunteers
- 25,000 people, healthy volunteers welcome
- Sponsor
- Truway Health, Inc.
Esophageal Cancer
AI-Driven Digital Twin and Drug Simulation for Esophageal Cancer
This study aims to integrate multi-omics data (genomics, transcriptomics, proteomics) from esophageal cancer patients with artificial intelligence and digital twin technology to construct personalized virtual patient models that…
- Trial name
- ESCA-DT (NCT07757022)
- Testing
- Toripalimab, Paclitaxel, Cisplatin
- Volunteers
- 400 people
- Sponsor
- Henan Cancer Hospital
Coronary Artery Disease, Atheroscleroses
Drug-Eluting Balloon Treatment vs. Guideline-Directed Medical Therapy for the Treatment of Lipid-Rich Plaques
The goal of this clinical trial is to find out whether treating vulnerable plaques in the coronary arteries with a drug-coated balloon can make them less dangerous than using standard medication alone.
- Conditions
- Coronary Artery Disease, Atheroscleroses, Cardiovascular Disease, Vulnerable Coronary Plaques
- Trial name
- DELETE-LRP (NCT07107971)
- Testing
- Paclitaxel-eluting balloon
- Where
- Netherlands
- Volunteers
- 400 people
- Sponsor
- Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Ophthalmology, Large Language Models
A Multimodal AI Agent for Ophthalmic Clinical Decision Support
This study is a multicenter randomized controlled trial evaluating the effectiveness and safety of EyeAgent, a multimodal artificial intelligence (AI) agent designed to assist ophthalmologists in clinical decision-making.
- Conditions
- Ophthalmology, Large Language Models, AI Agent, Eye Disease
- Trial name
- NCT07401459
- Testing
- EyeAgent AI system
- Where
- China
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- The Hong Kong Polytechnic University
Intraoperative Hypotension, Hemodynamic Instability
AI-Assisted Blood Pressure Control During Anesthesia
This proof-of-concept randomized controlled trial evaluates a reinforcement learning (RL)-based clinical decision support system for intraoperative hemodynamic management during non-cardiac surgery.
- Trial name
- RL-PRAIS PoC (NCT07123675)
- Testing
- Device: AI Clinical Decision Support System, Procedure: Standard of Care Anesthesia
- Where
- 2 sites in China
- Volunteers
- 40 people
- Sponsor
- Beijing Tsinghua Chang Gung Hospital
Clinical Decision Support Systems, Diagnostic Reasoning
Effects of Agent-assisted, LLM-assisted and Traditional Workflows on Diagnosis and Management Planning at Admission
The goal of this clinical trial is to evaluate whether AI-assisted workflows improve physicians' admission diagnosis and management planning performance on standardized simulated inpatient cases, among practicing internal…
- Conditions
- Clinical Decision Support Systems, Diagnostic Reasoning, Artificial Intelligence (AI)
- Trial name
- NCT07760051
- Testing
- Agent-assisted workflow, LLM-assisted workflow, Traditional Workflow
- Where
- China
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Asperger's Disorder, Asperger Disorder
QAIAx - SGI/SI Smart Health Cities: Microcity Enclave Program (Quantum SI/AGI Agency a/k/a AI City Hall Project - UPSTO App Nos. 64/074,526, 64/063,557, 64/105,164, 63/903,181, 63/729,428, 64/125,360; USPTO EO 9424 Assignment ID: 2101042 / ARN: REEL/FRAME: 76481/0026 - OUSD-R&E, Department of War)
BRIEF SUMMARY A. "What is the purpose of this study?" BACKGROUND. The QAIAx clinical trial (Quantum SI/SGI Public Health Agency), known operationally as the "AI City Hall Project," represents a landmark intergovernmental research…
- Conditions
- Asperger's Disorder, Asperger Disorder, Autism Disorder, Autism
- Trial name
- QAIAx (NCT07661823)
- Testing
- AI City Hall Project (AIhealth4u - Public Health Central), AI City Hall Project (QAIAx Microcity A - AI Public Health Central)
- Where
- United States
- Volunteers
- 1,000,000 people, healthy volunteers welcome
- Sponsor
- Veterans Recovery Network Inc.
an Intelligent Teaching Agent for the "Epidemiology" Course of the MBBS Program, Students' Critical Thinking, Practical Ability and Learning Outcomes
Research and Application of an AI Agent-Based MBBS Course Assistant
Prior to the quasi-experiment, this study performed semi-structured interviews among Bachelor of Medicine and Bachelor of Surgery(MBBS) undergraduate students from the Belt and Road International Medical College, Zhejiang…
- Trial name
- NCT07752160
- Testing
- Socratic Agent for Guided Epidemiology, General LLM
- Where
- China
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- The Fourth Affiliated Hospital of Zhejiang University School of Medicine
Severe Mental Disorder, Schizophrenia
Prediction and Intervention Effect of Rehabilitation Status for Severe Mental Disorder Patients Based on Multimodal Analysis and AI Agents
Mental health issues represent a major public health and social problem that significantly impacts economic and social development.
- Conditions
- Severe Mental Disorder, Schizophrenia, Schizoaffective Disorder, Paranoid Psychosis
- Trial name
- NCT06904079
- Testing
- Gamified Digital Rehabilitation, Routine Care
- Where
- China
- Volunteers
- 82 people
- Sponsor
- Shanghai Mental Health Center
Hyperglycaemia, Hypertension
Developing an AI Pharmacy Chatbot for the Population of Hong Kong
The primary objective of this study is to is to develop a conversational AI service (chatbot) in Hong Kong to assist patients and caregivers with inquires related to Hospital Authority (HA)-prescribed medications, and to evaluate…
- Conditions
- Hyperglycaemia, Hypertension, Hyperlipidaemia, Artificial Intelligence (AI)
- Trial name
- NCT07037563
- Testing
- An AI pharmacy chatbot offering information related to HA-prescribed medication for hyperglycaemia, hypertension, and hyperlipidaemia
- Where
- 2 sites in Hong Kong
- Volunteers
- 280 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
Smoking Cessation, Early-Stage Cancer
Multi-Theory Model-Based AI Agent Intervention for Smoking Cessation in Early-Stage Cancer Patients
The goal of this clinical trial is to evaluate the effectiveness of a Multi-Theory Model (MTM)-based AI agent intervention for smoking cessation in early-stage cancer patients (clinical stage cTNM 0~II) who currently smoke.
- Conditions
- Smoking Cessation, Early-Stage Cancer, AI Agent
- Trial name
- NCT07827066
- Testing
- MTM-Based AI Agent for smoking cessation, Counseling
- Volunteers
- 156 people
- Sponsor
- Sun Yat-sen University
Clinical Reasoning in Nursing Education, Virtual Simulation
MAGICS - Multi-Agent Generative AI in Clinical Simulation for Clinical Deterioration Training
This study compares the effectiveness of a Generative AI-integrated blended simulation programme and high-fidelity simulation alone on nursing students' clinical reasoning and learning experience during deterioration training
- Conditions
- Clinical Reasoning in Nursing Education, Virtual Simulation, Artificial Intelligence in Education, Deterioration, Clinical
- Trial name
- MAGICS (NCT07872735)
- Testing
- Generative AI-integrated Blended Simulation, High Fidelity Simulation
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- National University of Singapore
Head and Neck Cancer
An Oncology Nurse AI Agent to Reduce Cancer Distress During Radiotherapy
The goal of this clinical trial is to assess the effectiveness of the Digi-Coach chatbot for reducing physical and psychological distress in people undergoing radiotherapy for head and neck cancer.
- Trial name
- Digi-Coach (NCT06636188)
- Testing
- Digi-Coach Chatbot
- Where
- 2 sites in Hong Kong
- Volunteers
- 138 people
- Sponsor
- The University of Hong Kong
Liver Cirrhosis
AI-SC Multi-center Study
To examined the opportunity for Artificial Intelligence (AI) agents to evaluate transplant candidacy objectively at LT-SC, with a large language models (LLM) representing the expertise of each individual specialist (hepatologist…
- Trial name
- NCT07885007
- Testing
- evaluate the alignment between AI-SC recommendations and LT-SC decisions, Multi AI-SC model
- Where
- Canada
- Volunteers
- 1,000 people
- Sponsor
- University Health Network, Toronto
Influenza, Human, Vaccine Hesitancy
Conversational AI for Adult Flu Vaccination Decisions
This randomized trial tests whether an online guide combining short evidence cards with an AI-guided conversation increases flu-vaccination intention among US adults who haven't decided whether to get a flu vaccine this season.
- Trial name
- NCT07896850
- Testing
- Flu vaccination guide, Accident safety guide
- Where
- United States
- Volunteers
- 220 people, healthy volunteers welcome
- Sponsor
- Calypta Systems, Inc.
Chatbot-Based Training, Hemodialysis
DialysisBot: AI Chatbot for Hemodialysis Self-Management
End-stage kidney disease requiring hemodialysis is a chronic condition with substantial clinical, functional, and psychosocial burden.
- Conditions
- Chatbot-Based Training, Hemodialysis, Self-management
- Trial name
- NCT07830810
- Testing
- DialysisBot
- Where
- Italy
- Volunteers
- 40 people
- Sponsor
- University of Rome Tor Vergata
Urinary Stones, Prostate Cancer
Development of an AI-Agent for Urological Disease Diagnosis and Treatment
Urological diseases such as urinary stones, prostate cancer, and bladder cancer are very common and often require highly specialized diagnosis and treatment.
- Conditions
- Urinary Stones, Prostate Cancer, Bladder Cancer
- Trial name
- NCT07721935
- Where
- 3 sites in China
- Volunteers
- 2,000 people
- Sponsor
- Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University
Keratoconus, Refractive Surgery
AI-Orchestrated Workflow Versus Consultant Ophthalmologist for Refractive Surgery and Keratoconus Diagnosis (AEYE Trial)
Background and Rationale: Laser vision correction procedures, such as LASIK (Laser-Assisted In Situ Keratomileusis), PRK (Photorefractive Keratectomy), and SMILE (Small Incision Lenticule Extraction), are highly effective but…
- Conditions
- Keratoconus, Refractive Surgery, Machine Learning, Artifical Intelligence
- Trial name
- AEYE (NCT07096232)
- Testing
- Multi-Agent AI Diagnostic Workflow (AEYE)
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Hazem Yassin Clinics