Clinical trials: AIDS
HIV/AIDS
A Mobile Phone Game to Prevent HIV Among Young Africans
This project will test the feasibility of an electronic game to prevent HIV among African preadolescents, delivered via inexpensive Android smart phones.
- Trial name
- NCT03054051
- Testing
- Tumaini Mobile Phone Game
- Where
- Kenya
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Emory University
HIV Infections
Effect of Therapeutic and Supratherapeutic Oral Doses of GSK3640254 on Cardiac Conduction Compared to Placebo and a Single Oral Dose of Moxifloxacin
This study will aim to evaluate the effect of therapeutic and supratherapeutic oral doses of GSK3640254 on cardiac conduction compared to placebo and a single oral dose of Moxifloxacin in healthy adult participants.
- Trial name
- NCT04563845
- Testing
- GSK3640254, Moxifloxacin
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- ViiV Healthcare
HIV Infections
Safety and Drug Detection Study of Dapivirine Vaginal Ring and Oral TRUVADA® in Breastfeeding Mother-Infant Pairs
The purpose of this study is to evaluate the safety and drug detection of the dapivirine vaginal ring and oral Truvada in breastfeeding mother-infant pairs.
- Trial name
- NCT04140266
- Testing
- Dapivirine (DPV) Vaginal Ring (VR)-004, Truvada Tablet
- Where
- 4 sites in Malawi, South Africa and 2 more
- Volunteers
- 394 people, healthy volunteers welcome
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Drug Interaction
Pharmacokinetics and Pharmacodynamics of the Etonogestrel Contraceptive Implant When Co-administered With Efavirenz
This study evaluates whether there is an interaction between etonogestrel, the progestin hormone released by the contraceptive implant Nexplanon, and efavirenz, a common medication used to treat HIV.
- Trial name
- NCT01980342
- Testing
- Efavirenz
- Where
- United States
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
HIV, Pre-exposure Prophylaxis
Life Steps for PrEP for Youth
This is a formative study, designed to provide information required to tailor Life-Steps for Pre-Exposure Prophylaxis (PrEP), an evidence-based cognitive behavioral adherence intervention, to enhance PrEP uptake and adherence in…
- Conditions
- HIV, Pre-exposure Prophylaxis, Medication Adherence
- Trial name
- LSPY (NCT03805451)
- Testing
- Life Steps for PrEP for Youth
- Where
- 3 sites in United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Fenway Community Health
Adherence to Medication Regime
Early Antiretroviral Therapy and Pre-exposure Prophylaxis for HIV Prevention Among Female Sex Workers in Cotonou, Benin
In the last few years, early treatment of HIV-infected individuals, or "treatment as prevention (TasP), and pre-exposure prophylaxis with antiretroviral drugs among HIV-negative people at very high-risk of acquiring the infection…
- Trial name
- TasP/PrEP (NCT02237027)
- Testing
- TasP using ART regimen as per Benin guidelines, PrEP using Truvada
- Where
- Benin
- Volunteers
- 361 people, healthy volunteers welcome
- Sponsor
- CHU de Quebec-Universite Laval
HIV Health Literacy
Facilitating HIV/AIDS and HIV Testing Literacy for Emergency Department Patients
The Centers for Disease Control and Prevention (CDC) recommends that all patients should receive information about HIV/AIDS and HIV testing orally or in writing at every HIV testing encounter.
- Trial name
- NCT02284451
- Testing
- Video or Pictorial Brochure
- Volunteers
- 1,200 people, healthy volunteers welcome
- Sponsor
- Rhode Island Hospital
HIV/AIDS
Outcomes of Differentiated Models of Antiretroviral Treatment (ART) Provision
The aim of this study is to evalulate the effectiveness and cost-effectiveness of three models of ART provision for stable ART patients.
- Trial name
- [MMD] (NCT03438370)
- Testing
- Three monthly ART supply at CAGs, Six monthly ART supply at outreaches
- Where
- Lesotho
- Volunteers
- 5,760 people, healthy volunteers welcome
- Sponsor
- Equip, Lesotho
HIV Infections
ADAPT-POL: Planned Parenthood Center of El Paso Adopting and Demonstrating the Adaptation of Prevention Techniques
This study will look at the following questions: Was there a significant difference in HIV prevention knowledge, risk reduction attitudes, norms, intentions, self efficacy, number of sexual partners, and incidence of unprotected…
- Trial name
- NCT00252083
- Testing
- Popular Opinion Leader
- Where
- United States
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- Centers for Disease Control and Prevention
HPV, HIV
Long Term Immunogenicity of Quadrivalent Human Papillomavirus Vaccine (Gardasil®)in HIV-infected Adolescents and Young Adults
Infection with human immunodeficiency virus (HIV) is an important risk factor for HPV infection and the development of HPV-associated lesions in female and male anogenital tract.
- Trial name
- NCT01512784
- Testing
- Quadrivalent Human Papillomavirus (6, 11, 16 and 18) vaccine (Gardasil ®)
- Where
- Italy
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Milan
HIV/AIDS
Assessing the Impact of an Educational HIV Prevention Intervention in Zambia
In Zambia, 13% of the 15 to 49 year old population lives with HIV. The highest number of new HIV infections is among young people.
- Trial name
- NCT03316040
- Testing
- JIC
- Where
- 3 sites in United States, Zambia
- Volunteers
- 8,270 people, healthy volunteers welcome
- Sponsor
- Columbia University
HIV Negative and Not Yet on PrEP
PrEP Talk: PrEP Uptake With Young Black MSM and Their Close Friends
Young Black MSM (YBMSM) are at critically high and disproportionate HIV risk. Reducing HIV incidence rates among YBMSM will likely require increased adoption of additional strategies such as pre-exposure prophylaxis (PrEP).
- Trial name
- PrEP-Talk (NCT04601649)
- Testing
- PrEP Talk
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- California State University, Dominguez Hills
Hiv
A Clinical Trial to Evaluate the Safety and Immunogenicity of a Prophylactic HIV Vaccine Candidate
An Open-Label Study to Evaluate the Safety and Immunogenicity of 2 Doses of 100µg BG505 SOSIP.664 gp140 Vaccine, Adjuvanted, given to a Population of Adults in Good General Health Who have Received 3 doses of 300µg BG505…
- Trial name
- NCT05863585
- Testing
- BG505 SOSIP.664 gp140 Vaccine, Adjuvanted (3M-052 AF plus alum)
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- International AIDS Vaccine Initiative
HIV Prevention
An Exploratory Study of Potential Sources of Efficacy Dilution in the VOICE Trial (MTN-003)
This study is primarily exploratory and is designed to both identify factors that may have affected participant adherence to study product in VOICE, and describe how sexual behaviors, such as anal sex, may have had an effect on…
- Trial name
- NCT02358616
- Where
- 5 sites in South Africa, Uganda and 1 more
- Volunteers
- 219 people, healthy volunteers welcome
- Sponsor
- Microbicide Trials Network
Prevention
Adaptive Intervention to Facilitate PrEP Uptake/Adherence Among Transgender Women
"PrEP N' Shine" is a two-stage randomized controlled pilot trial which utilizes a behavioral intervention to optimize the uptake and adherence of Pre-exposure Prophylaxis (PrEP) in Transgender women (TGW).
- Trial name
- NCT05016232
- Testing
- PrEP N' Shine: Strength Based Case Management (Stage 1), PrEP N' Shine: Stepped Adherence Training and Counseling (Stage 2)
- Where
- United States
- Volunteers
- 123 people, healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
HIV Infection
Connect to Protect (C2P): Building a Community-Based Infrastructure for HIV Prevention
The proposed study seeks to continue the implementation of Connect to Protect® (C2P), a community mobilization intervention, which entails developing coalitions to plan for and bring about structural changes for purposes of…
- Trial name
- NCT01752504
- Testing
- Community Mobilization
- Where
- 5 sites in United States
- Volunteers
- 650 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Colorectal Cancer
Using Multimedia Approaches to Communicate Probabilities in Patient Decision Aids for Low-Literacy Populations: Randomized Trial
The goal of this research study is to compare how people who are 45-75 years old respond to 3 different versions of a program about screening tests for colorectal cancer.
- Trial name
- NCT02151032
- Testing
- Booklet, Audio CD, Video with Non-Moving Images
- Where
- 4 sites in United States
- Volunteers
- 189 people, healthy volunteers welcome
- Sponsor
- M.D. Anderson Cancer Center
HIV/AIDS and Infections
POSSE Project: A Community-Level Intervention for Black YMSM
Black young men who have sex with men (BYMSM) are at high risk for contracting and transmitting HIV, and represent a priority population for developing effective interventions.
- Trial name
- NCT03198663
- Testing
- POSSE
- Where
- 2 sites in United States
- Volunteers
- 1,037 people, healthy volunteers welcome
- Sponsor
- Cook County Health
Oral Pre-exposure Prophylaxis (PrEP), Long-acting Injectable Cabotegravir for PrEP
PathToScale: The PERSIST Trial
The purpose of this study is to identify the effectiveness of a bundle of strategies to support continuation of clients on pre-exposure prophylaxis, including long-acting injectable cabotegravir and oral pre-exposure prophylaxis…
- Trial name
- NCT07221747
- Testing
- Standard of Care (SoC), Enhanced continuation support package
- Where
- Malawi
- Volunteers
- 9,900 people, healthy volunteers welcome
- Sponsor
- Georgetown University
HIV Infections
Resistance to HIV Infection
The immune systems of some individuals may be capable of resisting HIV infection. These individuals do not appear to be infected with HIV despite multiple sexual encounters with HIV infected partners.
- Trial name
- NCT00069485
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.