Clinical trials: AIS
Ischemic Stroke, Acute, Tumor Progression
Predictive Value of Human Microbiome and Serological Markers for Clinical Outcome of AIS With Active Cancer
Explore with active cancer patients with acute ischemic stroke in the human body characteristic microorganism disorder to clinical prognosis of the predictive value of the secondary objective: to observe with active cancer…
- Trial name
- NCT05553990
- Testing
- intestinal flora disturbance
- Where
- China
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Nanfang Hospital, Southern Medical University
Scoliosis Idiopathic Adolescent Treatment
Myofascial and Articular Treatment of Adolescent Idiopathic Scoliosis
Randomized controlled trial of participants with scoliosis into standard treatment with observation/bracing and the other group will have the added treatment of dynamic myofascial manipulation for 6 months.
- Trial name
- NCT05423509
- Testing
- Dynamic myofascial manipulation, Standard AIS treatment with observation or bracing
- Where
- United States
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- University of New Mexico
Adolescent Idiopathic Scoliosis
Investigation of Muscle Activity With sEMG, Surface Topography and Radiographic Changes of Paraspinal Muscles in Individuals With Adolescent Idiopathic Scoliosis.
The aim of this study is to examine paraspinal muscle activity, body surface topography, posture, and radiographic characteristics in adolescents with idiopathic scoliosis.
- Trial name
- NCT07804836
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Akdeniz University
Adolescent Idiopathic Scoliosis, Single Nucleotide Polymorphisms
Investigation of LBX1, TIMP2, GPR126 and CHD7 Gene Polymorphisms in Adolescent Idiopathic Scoliosis Patients
Adolescent Idiopathic Scoliosis (AIS) is a common disease of the spine observed in individuals aged 10-18 who typically do not have any other health issues.
- Trial name
- NCT06540924
- Testing
- single nucleotide polymorphisms
- Where
- Turkey (Türkiye)
- Volunteers
- 301 people, healthy volunteers welcome
- Sponsor
- Uludag University
Idiopathic Adolescent Scoliosis
Altered Hemorology in Adolescent Idıopathic Scoliosis
This study aims to investigate potential alterations in hemorheological parameters in adolescents with idiopathic scoliosis (AIS) compared to healthy controls.
- Trial name
- AHIAIS (NCT07102862)
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Fatih Sultan Mehmet Training and Research Hospital
Adolescent Idiopathic Scoliosis
Cardiovascular Responses in Adolescent Idiopathic Scoliosis Girls
The aims of this pilot study are to determine the metabolic demand and exercise intensity level of E-Fit exercise intervention by evaluating the cardiovascular responses in AIS girls and whether the cardiovascular responses for…
- Trial name
- NCT04868331
- Testing
- Exercise
- Where
- Hong Kong
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Tung Wah College
Scoliosis Idiopathic, Scoliosis; Adolescence
Trunk Proprioception in Adolescent Idiopathic Scoliosis
Aims of this clinical research: To investigate trunk proprioception in all three planes in individuals with adolescent idiopathic scoliosis (AIS), To investigate the pelvis orientation sense in all three planes in individuals…
- Trial name
- NCT05326256
- Testing
- Exercise training- PSSE, Exercise training- PSSE with vestibular exercises
- Where
- Turkey (Türkiye)
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Hasan Kalyoncu University
HPV Infections, Cervical Cancer
Immunobridging Study of 9-valent Human Papillomavirus Recombinant Vaccine in Chinese Females Aged 9 to 19 Years
This phase 3 study will evaluate the immunogenicity and safety of 9-valent HPV recombinant vaccine in Chinese females aged 9 to 45 years
- Conditions
- HPV Infections, Cervical Cancer, Vulvar Cancer, Vaginal Cancer
- Trial name
- NCT04895020
- Testing
- 9-valent HPV vaccine
- Where
- China
- Volunteers
- 1,200 people, healthy volunteers welcome
- Sponsor
- Shanghai Bovax Biotechnology Co., Ltd.
Scoliosis; Adolescence, Bone Diseases
Thumb Ossification Composite Index (TOCI) to Predict Skeletal Maturity and Curve Progression in AIS
Accurate skeletal maturity assessment is important for prediction of curve progression and clinical management of adolescent idiopathic scoliosis (AIS) including bracing decision and counseling for prognosis.
- Conditions
- Scoliosis; Adolescence, Bone Diseases, Bone Growth Abnormal
- Trial name
- TOCI (NCT03904914)
- Testing
- TOCI
- Where
- Hong Kong
- Volunteers
- 1,500 people, healthy volunteers welcome
- Sponsor
- Chinese University of Hong Kong
Androgenetic Alopecia
Association of Polymorphisms in the Androgen Receptor Gene and Finasteride Response in Women With Androgenetic Alopecia
Previous studies of finasteride treatment in women with hair loss have failed to show positive results, yet, some women have responded anecdotally.
- Trial name
- NCT01052870
- Testing
- Finasteride
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- HairDx, LLC
Cervical Cancer, Genital Wart
A Phase Ⅲ Study to Evaluate the Efficacy, Immunogenicity, Safety of Quadrivalent HPV Recombinant Vaccine in Chinese Healthy Females
This study is designed to evaluate the vaccine efficacy, immunogenicity and safety of the 4-valent Human Papillomavirus (Types 6, 11, 16, and 18) Recombinant Vaccine (Hansenula Polymorpha) in Chinese Female Subjects Aged 18-45…
- Conditions
- Cervical Cancer, Genital Wart, CIN1, CIN2
- Trial name
- NCT05584332
- Testing
- Quadrivalent Human Papillomavirus (Types 6, 11, 16, and 18) Recombinant Vaccine (Hansenula Polymorpha)
- Where
- China
- Volunteers
- 3,131 people, healthy volunteers welcome
- Sponsor
- Shanghai Bovax Biotechnology Co., Ltd.
Juvenile and Adolescent Idiopathic Scoliosis
3-D Correction of Adolescent Idiopathic Scoliosis (AIS) With Differential Metals
This study is designed to evaluate the coronal, sagittal, and axial correction of deformity secondary to adolescent idiopathic scoliosis utilizing a technique employing a posterior spinal fusion construct utilizing rods of…
- Trial name
- AIS (NCT05631821)
- Testing
- differential rod bending with rod contours (MESA Spinal System)
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Rush University Medical Center
Scoliosis Idiopathic, Telerehabilitation
Telerehabilitation Support for Home Exercise in Mild AIS
Adolescent idiopathic scoliosis (AIS) is a three-dimensional spinal deformity that affects postural alignment, function, and quality of life.
- Conditions
- Scoliosis Idiopathic, Telerehabilitation, Exercise
- Trial name
- NCT07260383
- Testing
- home exercise, telerehabilitation
- Where
- Turkey (Türkiye)
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- Saglik Bilimleri Universitesi
Adolescent, Scoliosis
Sleep Quality in Adolescents With Idiopathic Scoliosis
This controlled cross-sectional observational study aims to compare sleep quality between adolescents with idiopathic scoliosis and age- and sex-similar healthy controls.
- Conditions
- Adolescent, Scoliosis, Adolescent Idiopathic Scoliosis (AIS)
- Trial name
- AIS-SLEEP (NCT07767591)
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Bezmialem Vakif University
Scoliosis Idiopathic, Scoliosis; Adolescence
Incobotulinumtoxin A and Yoga-like Isometric Exercise in Adolescent Idiopathic Lumbar Scoliosis
The study uses a yoga-like isometric posture and botulinum injections to reduce the curves in adolescent idiopathic lumbar scoliosis.
- Conditions
- Scoliosis Idiopathic, Scoliosis; Adolescence, Scoliosis; Lumbar Region
- Trial name
- NCT04922983
- Testing
- Botulinum toxin type A, Isometric Yoga-like exercise
- Where
- United States
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Manhattan Physical Medicine and Rehabilitation, LLP
Papillomavirus Infections, Uterine Cervical Neoplasms
Safety and Immunogenicity Study of V503 (GARDASIL™9, 9vHPV Vaccine) Administered to 9- to 26-Year-Old Females and Males in Vietnam (V503-017)
This study will evaluate the safety and immunogenicity of V503 (GARDASIL™9, 9vHPV vaccine) administered to 9- to 26-year-old females and males in Vietnam.
- Conditions
- Papillomavirus Infections, Uterine Cervical Neoplasms, Vulvar Neoplasms, Vaginal Neoplasms
- Trial name
- NCT03546842
- Testing
- 9vHPV vaccine
- Where
- Vietnam
- Volunteers
- 201 people, healthy volunteers welcome
- Sponsor
- Merck Sharp & Dohme LLC
Scoliosis Idiopathic, Scoliosis; Adolescence
Comparison of the Effects of Controlled Schroth Exercise and Home Exercise Programs
The aim of this study is to compare the effects of Schroth 3D exercise method on home symmetry, trunk topography, scapula symmetry, pelvic symmetry, health related quality of life and cosmetic deformity perception in adolescents…
- Trial name
- NCT04203394
- Testing
- Schroth Exercise Group, Home Exercise Group
- Where
- Turkey (Türkiye)
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- Eastern Mediterranean University
Cachexia
A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of GSK2849466 in Healthy Male Subjects
This study is the first administration of GSK2849466 in humans. This will be a single centre, randomized, double-blind, placebo-controlled study, to investigate the safety, tolerability, pharmacokinetics (PK), and…
- Trial name
- NCT01696604
- Testing
- GSK2849466
- Where
- United States
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Adolescent Idiopathic Scoliosis
Safety and Efficacy Study of Spinal Tethering
This study is an opportunity to gather long term safety and efficacy information from patients who have had their scoliosis treated via anterior vertebral body tethering (VBT).
- Trial name
- NCT02897453
- Testing
- The Spinal Tethering System
- Where
- United States
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Zimmer Biomet
Adolescent Idiopathic Scoliosis, Idiopathic Scoliosis
Adolescent Idiopathic Scoliosis and Proprioceptive Defect
This is the first clinical study to examine the spinal and peripheral proprioceptive deficits in longitudinal terms among subjects with adolescent idiopathic scoliosis.
- Conditions
- Adolescent Idiopathic Scoliosis, Idiopathic Scoliosis, Scoliosis
- Trial name
- NCT04682379
- Testing
- Proprioceptive assessment
- Where
- Hong Kong
- Volunteers
- 166 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong