Clinical trials: ALL
E-cigarette
Acute Health Effects of Short-term Use of E-cigarettes on Pulmonary and Cardiovascular System
The goal of our study was to assess acute, short term respiratory (airflow, FeNO, O2 saturation, exhaled air temperature) and cardiovascular (heart rate, blood pressure) responses to smoking an e-cigarette in exclusive e-smokers…
- Trial name
- NCT03742700
- Testing
- Cigarette smoking, E-cigarette use, Simulation of the use of e-cigarette
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Medical University of Silesia
Psychological Distress, Protein Deficiency
The Effect of Plasma Donation Frequency on Donor Health
This project is a randomized controlled non-inferiority study that aims to cover knowledge gaps about the composition and development of plasma proteins, inflammation markers and mental health in Norwegian, voluntary, and unpaid…
- Conditions
- Psychological Distress, Protein Deficiency, Inflammation
- Trial name
- NCT05179200
- Testing
- Plasmapheresis, Whole blood donation
- Where
- Norway
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Sykehuset Innlandet HF
Healthy
Safety and Pharmacokinetic Comparison of Co-administration and a Combination Drug of Rosuvastatin and Olmesartan in Healthy Male Volunteers
This study investigates safety and pharmacokinetic comparison of DWJ1276, a combination drug of Rosuvastatin and Olmesartan (test formulation), and co-administration of Rosuvastatin and Olmesartan (reference formulation) for…
- Trial name
- NCT01823900
- Testing
- Test formulation, Reference formulation
- Where
- South Korea
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- Severance Hospital
Fibrosis
Growth Hormone as a Model for Reversible Activation of Adipose Tissue Fibrosis
Background: Adipose tissue fibrosis denotes excessive pathological accumulation of extracellular matrix (ECM) in adipose tissue and is a marker of dysfunction.
- Trial name
- NCT04998500
- Testing
- Growth hormone, saline and GH receptor blockade (Pegvisomant)
- Where
- Denmark
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Osteoporosis
Balance and Muscle Strength as Indicators of Fracture Risk in Postmenopausal Women
The study is designed as a cross-sectional clinical study. A total of 156 postmenopausal women who visited the Physical Therapy and Rehabilitation outpatient clinic at Beylikdüzü State Hospital and have had Dual X-ray…
- Trial name
- NCT06645600
- Testing
- Fracture risk
- Where
- Turkey (Türkiye)
- Volunteers
- 156 people, healthy volunteers welcome
- Sponsor
- Beylikduzu State Hospital
Infection, Human Immunodeficiency Virus
A Study to Investigate the Pharmacokinetics, Safety and Tolerability of GSK1349572 (Dolutegravir, DTG) in Healthy Japanese Subjects
This study is a Phase 1, open label, non-randomized, single dose study to determine pharmacokinetics, safety and tolerability of doultegravir (DTG) following 50 mg single oral administration in healthy Japanese subjects.
- Trial name
- NCT01332565
- Testing
- GSK1349572
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- ViiV Healthcare
Psychological Stress, Anesthesia
RELIEF OF PSYCHOEMOTIONAL STRESS USING XENON SEDATION
The goal of this clinical trial is to propose for implementation and evaluate the effectiveness of xenon sedation for the relief of psychoemotional stress disorder before the operation of refractive laser vision correction…
- Conditions
- Psychological Stress, Anesthesia, Anxiety, Xenon
- Trial name
- NCT06080100
- Testing
- Xenon, premedication hydroxyzine 25 mg
- Where
- Russia
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- The S.N. Fyodorov Eye Microsurgery State Institution
Internet Addiction, Gaming Disorder
Prevalence of Behavioral Addiction and Its Relation With Psychological Disturbance
Internet usage has increased greatly. It is expected to be more than 4 billion by the end of this year. About 80% of them spend most of their internet time on social media, and are expected by 2026 to be about 50% of the total…
- Conditions
- Internet Addiction, Gaming Disorder, Porn Addiction
- Trial name
- NCT07174700
- Testing
- Questionnaire
- Where
- Egypt
- Volunteers
- 5,994 people, healthy volunteers welcome
- Sponsor
- Zagazig University
Sexual Behavior, Literacy
Sexual Health Literacy Scale
According to the World Health Organization, sexual health is a state of well-being related to sexuality as a whole, not just the absence of disease or dysfunction or disability.
- Conditions
- Sexual Behavior, Literacy, Sexuality
- Trial name
- SHLS (NCT05821907)
- Testing
- data collection group
- Where
- Turkey (Türkiye)
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Nurdan Demirci
Pilonidal Sinus
Comparative Study Between Wide Local Excision and Minimal Excision of Pilonidal Sinus
Comparative study between wide local excision and minimal excision of pilonidal sinus
- Trial name
- NCT06021392
- Testing
- Z plasty and minimal excision of pilonidal sinus
- Volunteers
- 2 people, healthy volunteers welcome
- Sponsor
- Abanoub emad fayez
Thromboembolic Disorders
A Trial to Learn How a New Liquid Form of Rivaroxaban Behaves and How Safe it is Compared to the Current Tablet Form of Rivaroxaban in Healthy Male Participants
Researchers were looking for another way to treat people with a blood clot in their veins. Before a treatment can be approved for people to take, researchers do clinical trials to better understand its safety and how it behaves.
- Trial name
- NCT04720092
- Testing
- Rivaroxaban (Xarelto, BAY59-7939)
- Where
- Germany
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Bayer
Ventricular Premature Complexes
Relativity Study Between Idiopathic Ventricular Arrhythmia and Sex Hormone Levels in Different Stages of Menstrual Cycle
The purpose of this study is to determine whether the occurrence of idiopathic right ventricular outflow tract(RVOT) arrhythmia is relative to sex hormone levels in different stages of female menstrual cycle
- Trial name
- NCT00606736
- Where
- China
- Volunteers
- healthy volunteers welcome
- Sponsor
- Harbin Medical University
SIAD - Syndrome of Inappropriate Antidiuresis, Hyponatremia
Effects of Intravenous [Pyr1]Apelin-13 on Healthy Volunteers With Artificially Induced SIAD
Hyponatremia is a common electrolyte imbalance which often results from hormonal disregulation. The study aims to investigate whether the apelin hormone, which plays a role in regulating salt and water balance in the body, can be…
- Trial name
- ESCAPE (NCT06277336)
- Testing
- Apelin Low Dose, Apelin High Dose, Selected Apelin Dose
- Where
- Switzerland
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- University Hospital, Basel, Switzerland
Hepatitis B
Efficacy Study of Combined Hepatitis A and Hepatitis B Vaccine to Protect Against Hepatitis B in Hemodialysis Patients
Does vaccinating hemodialysis patients with Twinrix® (combination vaccine against hepatitis A and hepatitis B) result in a difference in hepatitis B antibody response in comparison to the monovalent hepatitis B vaccine? Hepatitis…
- Trial name
- NCT00186836
- Testing
- Engerix-B and Twinrix
- Where
- Canada
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- St. Joseph's Health Care London
Hemorrhage
Safety, Tolerability, PK and PD of BI 655075 and Establishment of BI 655075 Dose(s) Effective to Reverse Prolongation of Blood Coagulation Time by Dabigatran
To investigate safety, tolerability, PK and PD of BI 655075 and to establish the BI 655075 dose(s) effective to reverse prolongation of blood coagulation time by dabigatran
- Trial name
- NCT01955720
- Testing
- BI 655075
- Where
- Belgium
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Boehringer Ingelheim
Periapical Lesion Healing, Apical Periodontitis
The Effect of Different Intracanal Medicaments on Periapical Lesion Healing
This study is planned to evaluate the effects of two different intracanal medicaments-calcium hydroxide and diclofenac sodium-on periapical healing following endodontic retreatment.
- Trial name
- NCT07237620
- Testing
- Diclofenac sodium
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Mustafa Kemal University
Chronic Obstructive Pulmonary Disease
Innate Immunity in COPD
Chronic Obstructive Pulmonary Disease (COPD) causes obstruction to airflow when breathing out. It is a leading cause of chronic lung disease, hospitalization and death.
- Trial name
- NCT05743582
- Testing
- Bronchoscopy for sample collection, Blood donation
- Where
- 2 sites in United Kingdom
- Volunteers
- 189 people, healthy volunteers welcome
- Sponsor
- University of Edinburgh
Healthy
A Study to Learn More About the Study Medicine PF-07264660 in Healthy Chinese Adult Participants
The purpose of this study is to learn if the study medicine (called PF-07264660) is safe and how it is processed in healthy Chinese participants. This study is seeking participants who: are between 18 to 65 years of age.
- Trial name
- NCT06712082
- Testing
- PF-07264660
- Where
- 2 sites in China
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Pfizer
Cystic Fibrosis
Pilot Mouthwash Study of Pioglitazone and Simvastatin in Healthy Volunteers
Inflammation clearly contributes to the progression of the cystic fibrosis (CF) lung disease, and administration of the anti-inflammatory agent high-dose ibuprofen retards the rate of decline of pulmonary function.
- Trial name
- NCT00531882
- Testing
- Pioglitazone, Simvastatin, Ibuprofen
- Where
- 2 sites in United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- University Hospitals Cleveland Medical Center
Food, Eating
The Effect of Buckwheat and Couscous on Satiety and Food Intake in Young Adults
A diet rich in whole grains has been linked to multiple beneficial health outcomes, including cardiovascular health, weight loss and a decreased risk of acquiring type 2 diabetes.
- Conditions
- Food, Eating, Appetite
- Trial name
- NCT04377282
- Testing
- Food-1, Food-2, Food-3
- Where
- Canada
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Mount Saint Vincent University
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