Clinical trials: AMI Patients
Myocardial Infarction, Heart Failure
A Critical Pathway for Implantable Cardioverter-Defibrillators in Patients With Ischemic Cardiomyopathy
The purpose of this study is to develop and implement a critical pathway to identify patients with ischemic cardiomyopathy who are candidates for an implantable cardioverter-defibrillator (ICD).
- Trial name
- CAPTURE (NCT01248702)
- Testing
- Use of the ICD Critical Pathway
- Where
- Canada
- Volunteers
- 600 people
- Sponsor
- University of British Columbia
Acute Coronary Syndromes (ACS)
Evaluation Through Innovative Examinations of Intestinal Dysbiosis Status in Patients Diagnosed With Cardiovascular Diseases and Evaluation of the Efficacy of Natural and Probiotic Extracts in the Non-pharmacological Approach to Improving Intestinal Dysbiosis Status.
The prospective experimental study aims to take an instantaneous photograph of the subject at time T0 and after 24 hours of intestinal permeability and dysbiosis indices in patients with acute coronary syndromes (ACS) which…
- Trial name
- DISBIO (NCT07429227)
- Testing
- Tea tree (Melaleuca alternifolia), Cinnamon (Cynnamomum zeylanicum) bark, Clove carnation (Eugenia caryopyllus) flowers, Red thyme (Thymus vulgaris) plant
- Where
- Italy
- Volunteers
- 15 people
- Sponsor
- Casa di Cura Dott. Pederzoli
Myocardial Infarction
Assessment of the Effects of Atorvastatin Therapy on Myocardial Deformation Characteristics, in Patients With STEMI
The primary goal To assess the effect of atorvastatin in patients treated since the first 24-96 hours of the disease on the parameters of global and regional myocardial deformation in the infarcted area and the structural and…
- Trial name
- CONTRAST (NCT02590653)
- Testing
- Atorvastatin
- Where
- Russia
- Volunteers
- 200 people
- Sponsor
- Penza State University
Cardiogenic Shock,, With ECMO or IABP Support,
The Analysis of Heart Rate Variability With 24hrs Holter ECG and Serum Cardiac Fibrosis Markers in Critical Illness Patients Who Are With Cardiogenic Shock, With ECMO or IABP Support, or With APACH II Score >25)
The study is to show the prognostic factor of HRV parameter and cardiac fibrosis markers in critical illness patients
- Conditions
- Cardiogenic Shock,, With ECMO or IABP Support,, With APACH II Score >25)
- Trial name
- NCT01993745
- Where
- Taiwan
- Volunteers
- 106 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Non-ST Elevated Myocardial Infarction, Electrocardiography
Clinical Characteristics, Treatments, and Outcomes of MI Patients Presenting With Normal ECG
the investigators aimed to analyzed data for hospitalized MI patients with normal ECG.
- Trial name
- NCT04710446
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Henan Provincial People's Hospital
Acute ST Segment Elevation Myocardial Infarction, Thrombolysis in Myocardial Infarction Flow
Ticagrelor in Patients With ST Elevation Myocardial Infarction Treated With Pharmacological Thrombolysis
Administration of Ticagrelor in patients with ST elevation myocardial infarction treated with pharmacological thrombolysis
- Trial name
- TREAT (NCT02298088)
- Testing
- Ticagrelor 180 mg, Clopidogrel
- Where
- 153 sites in Argentina, Australia and 8 more
- Volunteers
- 3,799 people
- Sponsor
- Hospital do Coracao
Acute Coronary Syndrome
Comparison Between the New Highly Sensitive Troponin T and the Conventional Troponin T Test in Elderly Patients
The planned cohort study shall clarify whether the use of biomarkers leads to improved diagnostic assessment of elderly patients.
- Trial name
- BOSCH2 (NCT01370382)
- Where
- Germany
- Volunteers
- 180 people
- Sponsor
- University of Erlangen-Nürnberg Medical School
Myocardial Infarction
Fractional Flow Reserve (FFR) Stability in Non-Culprit Vessels at ST Elevation Myocardial Infarction(STEMI)
It has been shown that if it can be accomplished within a 90 minute "door to balloon" time, opening an artery in an acute heart attack situation (ST elevation myocardial infarction or STEMI) is best treated with balloon…
- Trial name
- NCT01065103
- Testing
- FFR (Fractional Flow Reserve)
- Where
- 2 sites in Canada
- Volunteers
- 48 people
- Sponsor
- Cardiology Research UBC
Myocardial Infarction
Early Percutaneous Coronary Intervention (PCI) After Fibrinolysis Versus Standard Therapy in ST Segment Elevation Myocardial Infarction (STEMI) Patients
Several recent trials (1,2) suggest that all STEMI patients receiving fibrinolysis in non-PCI centres should be routinely transferred for elective early PCI within 24 hours from hospitalization, with no additive risk of major…
- Trial name
- NCT01014182
- Where
- United Kingdom
- Volunteers
- 3,000 people
- Sponsor
- Royal Brompton & Harefield NHS Foundation Trust
STEMI, PCI
Intravascular Ultrasound guidaNce versuS angIoGrapHy Guidance in Patients With ST-segment Elevation Myocardial Infarction
STEMI represents the subtype of ACS with the worst prognosis, associated with high mortality and an elevated risk of complications. The use of IVI guidance holds the potential to reduce the incidence of MACE.
- Trial name
- INSIGHT-STEMI (NCT07616024)
- Testing
- Intravascular Ultrasound, Coronary angiography guidance
- Where
- China
- Volunteers
- 2,488 people
- Sponsor
- Shanghai Zhongshan Hospital
Acute Myocardial Infarction
COOL AMI EU Pivotal Trial to Assess Cooling as an Adjunctive Therapy to PCI In Patients With Acute MI (Phase A)
The objective of this trial is to evaluate the safety and effectiveness of therapeutic hypothermia, using the ZOLL Proteus IVTM System, as an adjunctive therapy for patients presenting with acute anterior myocardial infarction…
- Trial name
- NCT03173313
- Testing
- Intravascular permissive hypothermia as an adjunct to PCI
- Where
- Slovenia
- Volunteers
- 111 people
- Sponsor
- ZOLL Circulation, Inc., USA
Myocardial Infarction
Percutaneous Coronary Intervention for Myocardial Infarction at Fujian Provincial Hospital
Research Objectives: This clinical trial aims to evaluate the efficacy and safety of percutaneous coronary intervention (PCI) in patients with myocardial infarction (MI).
- Trial name
- Fu-AMI (NCT07405788)
- Testing
- Percutaneous Coronary Intervention
- Volunteers
- 1,344 people, healthy volunteers welcome
- Sponsor
- Kaiyang Lin
Myocardial Infarction, Myocardial Ischemia
18F-fluorocholine PET-MR Imaging of Coronary Plaque Vulnerability
This study is designed as a prospective observational feasibility study. The investigators will study whether vulnerable plaques on OCT (fibrous cap ≤ 70 μm) show a locally increased uptake of 18F-choline on PET-MRI compared to…
- Conditions
- Myocardial Infarction, Myocardial Ischemia, Atherosclerosis, Coronary Artery Disease
- Trial name
- NCT03252990
- Testing
- PET-MRI, Optical Coherence Tomography
- Where
- Netherlands
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Maastricht University Medical Center
Non-ST Elevation Myocardial Infarction (nSTEMI)
Risk-score Based ICU Triage
The investigators have created a new risk score that predicts whether initially stable patients with myocardial infarctions (heart attacks) will require intensive care while they are in the hospital.
- Trial name
- NCT03390270
- Testing
- Admission with NSTEMI
- Where
- United States
- Volunteers
- 462 people
- Sponsor
- Duke University
Acute Myocardial Infarction
Cell Therapy in Myocardial Infarction
The purpose of this study is to determine cell therapy efficacy in patients with ST elevation acute myocardial infarction (STEMI)
- Trial name
- EMRTCC (NCT00350766)
- Testing
- Autologous Bone Marrow Mononuclear Cells (ABMMC) Transplantation
- Where
- Brazil
- Volunteers
- 166 people
- Sponsor
- Ministry of Health, Brazil
Acute Myocardial Infarction (AMI)
Stellate Ganglion Morphine Infiltration on Myocardial I/R Injury
The goal of this clinical trial is to investigate whether morphine modulates the functions of the stellate ganglion to reduce myocardial ischemia/reperfusion (I/R) injury in AMI patients.
- Trial name
- tSGM-AMI (NCT07023679)
- Testing
- Morphine
- Where
- 2 sites in China
- Volunteers
- 2,588 people
- Sponsor
- The Second Hospital of Anhui Medical University
Acute Coronary Syndrome, ST Elevation Myocardial Infarction
A Trial of Routine Aspiration Thrombectomy With Percutaneous Coronary Intervention (PCI) Versus PCI Alone in Patients With ST-Segment Elevation Myocardial Infarction (STEMI) Undergoing Primary PCI
This is an international, randomized, controlled, parallel group study in which patients with ST-Segment Elevation Myocardial Infarction (STEMI) will be allocated to one of the following: Manual aspiration thrombectomy with…
- Conditions
- Acute Coronary Syndrome, ST Elevation Myocardial Infarction, Percutaneous Coronary Intervention
- Trial name
- TOTAL (NCT01149044)
- Testing
- Percutaneous Coronary Intervention with or without manual aspiration thrombectomy
- Where
- 87 sites in United States, Australia and 18 more
- Volunteers
- 10,732 people
- Sponsor
- Population Health Research Institute
ST Elevation Acute Myocardial Infarction
Does Cyclosporine ImpRove Clinical oUtcome in ST Elevation Myocardial Infarction Patients at 3 Years of Follow-up. CIRCUS II Study
Infarct size is a major determinant of vital prognosis after AMI. We recently reported that cyclosporine A, when administered immediately prior to PCI reperfusion, can significantly reduce infarct size in STEMI patients.
- Trial name
- CIRCUS II (NCT02934217)
- Testing
- Injection of Cyclosporin, Echocardiography
- Where
- France
- Volunteers
- 868 people
- Sponsor
- Hospices Civils de Lyon
Acute Myocardial Infarction
MAGIC Cell-5-Combicytokine Trial
Combination use of darbepoetin and G-CSF will improve left ventricular systolic function in patients with acute myocardial infarction who receive intracoronary infusion of mobilized peripheral blood stem cell in comparison with…
- Trial name
- MAGIC Cell-5 (NCT00501917)
- Testing
- G-CSF with/without darbepoetin, peripheral blood stem cell infusion
- Where
- South Korea
- Volunteers
- 116 people
- Sponsor
- Seoul National University Hospital
Abdominal Aortic Aneurysm
Reduction of Myocardial Infarction by Preconditioning in Patients With Ruptured Abdominal Aortic Aneurysm
Preconditioning in patients treated for elective abdominal aneurysm showed that the rate of perioperative myocardial infarction could be reduced by 80 %(ARR from 27% to 5%).
- Trial name
- PreconRAAA (NCT00883363)
- Testing
- Precondition
- Where
- Denmark
- Volunteers
- 200 people
- Sponsor
- Nikolaj Eldrup