Clinical trials: ANTERIOR CRUCIATE LIGAMENT RECONSTRUCTION
Anterior Cruciate Ligament Reconstruction
Effect of Altered Mechanical Loading in ACLR
Altered loading is a causative factor for the development of knee osteoarthritis following anterior cruciate ligament reconstruction (ACLR), and real-time biofeedback may be an effective intervention to manipulate altered…
- Trial name
- NCT03035994
- Testing
- Real-Time Biofeedback
- Volunteers
- 30 people
- Sponsor
- University of North Carolina, Chapel Hill
Anterior Cruciate Ligament (ACL) Reconstruction Surgery
KRONOS Versus Breg T-Scope Post-operative Knee Braces Following Anterior Cruciate Ligament (ACL) Reconstruction
The purpose of this study is to evaluate how well the KRONOS postoperative knee brace reduces pain and enhances recovery compared with the standard Breg T-scope hinged brace following anterior cruciate ligament (ACL)…
- Trial name
- NCT07090616
- Testing
- Arm 1-Kronos brace, Arm 2-Breg T-Scope brace
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Rush University Medical Center
Pain
Femoral Nerve Block Versus Adductor Canal Nerve Block for Peri-Operative Analgesia Following Anterior Cruciate Ligament (ACL) Reconstruction: Evaluation of Post-operative Pain and Strength
All patients over the age of 16 undergoing primary or revision anterior cruciate ligament reconstruction with the use of bone-patellar-bone autograft are eligible for the study.
- Trial name
- NCT03033589
- Testing
- Marcaine 0.25 % Injectable Solution
- Where
- United States
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- Henry Ford Health System
Anterior Cruciate Ligament Injuries
Anterior Cruciate Ligament Reconstruction Made With Hamstring Tendon And Quadriceps Tendon Autografts
Anterior cruciate ligament reconstruction (ACLR) is one of the most common procedure all around the world, however optimal graft source for ACLR still remains controversial.
- Trial name
- NCT04940169
- Testing
- anterior cruciate ligament recontruction
- Where
- Turkey (Türkiye)
- Volunteers
- 38 people
- Sponsor
- SB Istanbul Education and Research Hospital
Anterior Cruciate Ligament Injuries
Reverse Drilling Technique in Improving Outcomes After Arthroscopic Anterior Cruciate Ligament Reconstruction
Anterior cruciate ligament (ACL) injuries and bone tunnel enlargement (BTE) after ACL reconstruction (ACLR) remain frequent issues.
- Trial name
- NCT05994872
- Testing
- Reverse drilling technique, Traditional extraction drilling
- Where
- 6 sites in China
- Volunteers
- 216 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Rehabilitation, Anterior Cruciate Ligament Reconstruction
Comparative Study Between Two Physiotherapy Protocols Conventional X Accelerated in Individuals Undergoing Reconstruction of the Anterior Cruciate Ligament.
The accelerated rehabilitation and early return does not seem to be harmful, but still needs further research to define the rehabilitation time is what shows Kruse and collaborators (2012) in their study of systematic review.
- Conditions
- Rehabilitation, Anterior Cruciate Ligament Reconstruction, Knee
- Trial name
- NCT01821599
- Testing
- Nonaccelerated Rehabilitation, Accelerated Rehabilitation
- Where
- Brazil
- Volunteers
- 29 people
- Sponsor
- University of Sao Paulo
ACL Injury, Sports Physical Therapy
The Effects of Preoperative Blood Flow Restriction Training in Patients Undergoing ACL Reconstruction
This prospective feasibility study is designed to assess pre-operative BFR in patients awaiting ACL reconstruction. This study will serve the following: (1) to determine if BFR improves strength testing prior to surgery and (2)…
- Trial name
- BFRACL (NCT06342063)
- Testing
- Blood Flow Restriction Therapy
- Where
- Canada
- Volunteers
- 32 people
- Sponsor
- Women's College Hospital
Anterior Cruciate Ligament Tear
Prospective Femoral Versus Femoral and Sciatic Nerve Block for Anterior Cruciate Ligament (ACL) Reconstruction
The investigators propose that a preoperative femoral and sciatic blocks vs a femoral block only, prior to ambulatory anterior cruciate ligament (ACL) reconstruction will lead to a decrease in opiate consumption, pain scores, and…
- Trial name
- NCT01447277
- Testing
- Sciatic Block, Femoral Block only
- Where
- United States
- Volunteers
- 68 people
- Sponsor
- University of California, San Francisco
Anterior Cruciate Ligament Reconstruction, Post-traumatic Osteoarthritis
STABILITY: Physical Activity Intervention at 7 Years Post-Anterior Cruciate Ligament Reconstruction
Anterior cruciate ligament (ACL) ruptures are very common knee injuries amongst youth involved in sports and are often treated through ACL reconstruction surgeries.
- Trial name
- NCT05152758
- Testing
- PARx
- Where
- Canada
- Volunteers
- 196 people
- Sponsor
- Western University, Canada
Anterior Cruciate Ligament Injury, Knee Injury
Comparison of Quadriceps and Semitendinosus Grafts in ACL Reconstruction Using Data From the Danish Knee Ligament Reconstruction Registry (DKRR)
This study looks at two different types of tendon (tissue) used in knee surgery to repair a torn anterior cruciate ligament (ACL), which is a common injury in active people.
- Conditions
- Anterior Cruciate Ligament Injury, Knee Injury, Ligament Reconstruction, Sports Injuries
- Trial name
- NCT06980285
- Where
- Denmark
- Volunteers
- 2,500 people
- Sponsor
- Abdirahman Hassan Omar
Anterior Cruciate Ligament Tear
Therapeutic Benefits of a Motor Imaging Protocol Following Anterior Cruciate Ligament Reconstruction Surgery
The purpose of this study is to compare changes in lower limb symmetry during functional and strength tests, before and after the motor imagery program, in patients who received the 3-week motor imagery program starting 3 months…
- Trial name
- IMAGERIEMOTR (NCT07210489)
- Testing
- Reconstructive surgery after anterior cruciate ligament rupture, sessions from a physical therapist
- Where
- France
- Volunteers
- 70 people
- Sponsor
- GCS Ramsay Santé pour l'Enseignement et la Recherche
Anterior Cruciate Ligament Injuries
Spatiotemporal Characteristics and Multi-body Dynamics Modeling Information After ACL Rupture and Reconstruction
High incidence rate of knee osteoarthritis and gait analysis are important for early assessment of biomechanics. ACL injury is an ideal clinical model for studying knee osteoarthritis.
- Trial name
- NCT04462432
- Testing
- no intervention
- Where
- China
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Peking University Third Hospital
Anterior Cruciate Ligament Reconstruction
Comparison of 3 Techniques for Recreation of Anterior Cruciate Ligament Anatomic Footprint
The purpose of this study is to compare the tomographic results of patients who underwent single-bundle anterior cruciate ligament reconstruction at the investigator's institution using the transtibial, accessory medial portal…
- Trial name
- NCT02795247
- Testing
- Anterior Cruciate Ligament Reconstruction
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- OrthoCarolina Research Institute, Inc.
Anterior Cruciate Ligament Reconstruction
The Effect of Upper Limbs Motion During Single-leg Jump Landing After Anterior Cruciate Ligament Reconstruction
The aim of this study is to investigate the effect of upper limbs motion on lower limb biomechanics and muscle activity during single-leg jump landing after anterior cruciate ligament reconstruction.
- Trial name
- NCT04629092
- Where
- Taiwan
- Volunteers
- 15 people
- Sponsor
- National Yang Ming Chiao Tung University
Anterior Cruciate Ligament Reconstruction
Early Mobilization of Knee Joint After ACL Surgery. Continuous Passive Motion Versus Manual Passive Mobilization
Anterior Cruciate Ligament (ACL) injuries by trauma are a prevalent pathology. In the USA, about 200.000 injuries are estimated per year, half of which implicate a total rupture of the ligament.
- Trial name
- NCT02748759
- Testing
- CPM, Manual mobilization
- Where
- Spain
- Volunteers
- 15 people
- Sponsor
- Jesús Montesinos Muñoz
Anterior Cruciate Ligament Reconstruction, Anterolateral Ligament Reconstruction
Rehabilitation Protocol for Reconstruction of Anterior Cruciate Ligament and Anterolateral Knee Ligament Surgery
Introduction: Individuals with an ACL lesion present abnormal rotational stability. Among the structures located in the anterolateral region of the knee that could act as restraints of the rotational knee lassitude, there is the…
- Conditions
- Anterior Cruciate Ligament Reconstruction, Anterolateral Ligament Reconstruction, Rehabilitation
- Trial name
- NCT03505359
- Testing
- partial knee immobilization protocol, standard ACL reconstruction rehabilitation protocol
- Where
- Brazil
- Volunteers
- 28 people
- Sponsor
- University of Sao Paulo General Hospital
Anterior Cruciate Ligament Injuries
Deficit in Quadriceps Voluntary Activation After Anterior Cruciate Ligament Reconstruction: Roles of the "Learned Non-use" Paradigm and the Interhemispheric Inhibition
Anterior cruciate ligament (ACL) tear is mainly caused by sport injuries. 40% of injuries are attributed to noncontact mechanisms involving pivoting.
- Trial name
- AQUARIUS (NCT04837417)
- Testing
- Pathologic group
- Where
- 2 sites in Italy
- Volunteers
- 10 people
- Sponsor
- Istituto Auxologico Italiano
Anterior Cruciate Ligament Rupture With Ligamentoplasty
Evaluation of the Evolution of Proprioceptive Reweighting Abilities Following Anterior Cruciate Ligament Reconstruction Surgery
Anterior cruciate ligament (ACL) injury is the most common knee injury among athletes who play contact sports involving pivoting.
- Trial name
- ReproEVO (NCT07389850)
- Testing
- ReproEVO intervention
- Where
- 3 sites in France
- Volunteers
- 34 people
- Sponsor
- University Hospital, Brest
ACL, Postoperative Pain
Exparel vs Block for ACL Reconstruction
Liposomal bupivacaine or Exparel (Pacira Biosciences) is a long-lasting nonopioid analgesic that was initially utilized as an infiltrative agent but has more recently become U.S.
- Trial name
- NCT06006624
- Testing
- Exparel 30 mL, 0.5% bupivacaine, Dexamethasone
- Where
- United States
- Volunteers
- 154 people, healthy volunteers welcome
- Sponsor
- Rothman Institute Orthopaedics
Anterior Cruciate Ligament Reconstruction, Anterior Cruciate Ligament Reconstruction Rehabilitation
Fractal vs Isochronous Cueing in Athletes After ACL Reconstruction
Anterior cruciate ligament (ACL) injuries are among the most prevalent and functionally limiting knee injuries in sports, particularly those that involve pivoting movements.
- Conditions
- Anterior Cruciate Ligament Reconstruction, Anterior Cruciate Ligament Reconstruction Rehabilitation, Athlete
- Trial name
- SyncGait (NCT07243535)
- Testing
- Fractal Cueing, Isochronous Cueing
- Where
- Portugal
- Volunteers
- 36 people
- Sponsor
- Egas Moniz - Cooperativa de Ensino Superior, CRL