Clinical trials: ANTERIOR CRUCIATE LIGAMENT RECONSTRUCTION
Post ACL Reconstruction
Rate of Force Development vs Isometric Strength of Quadriceps
Peak isometric strength of quadriceps (QI) has been used to help determine an athletes ability to safely return back to sport following an anterior cruciate ligament (ACL) reconstruction surgery.
- Trial name
- NCT04005274
- Where
- United States
- Volunteers
- 19 people
- Sponsor
- Kaiser Permanente
ACL Injury, Knee Injuries
Subjective Outcomes After ACL Reconstruction With BQT Autograft
The purpose of the study is to compare short-term patient reported outcome measures (PROM) of Bone-Quadriceps-Tendon (BQT) autograft with Semitendinosus-Gracilis (STG) and Bone-Patellar-Tendon-Bone (BPTB) autografts following…
- Trial name
- NCT04901559
- Testing
- Graft type at ACLR
- Volunteers
- 30,000 people
- Sponsor
- Region Zealand
Femoral Triangle Block, Adductor Canal Block
Femoral Triangle Block Versus Adductor Canal Block in Arthroscopic Anterior Cruciate Ligament Reconstruction
The aim of this study is to compare the postoperative analgesic effect of femoral triangle block (FTB) and adductor canal block (ACB)after arthroscopic anterior cruciate ligament (ACL) reconstruction.
- Conditions
- Femoral Triangle Block, Adductor Canal Block, Anterior Cruciate Ligament Reconstruction
- Trial name
- NCT06402110
- Testing
- Femoral Triangle Block, Adductor Canal Block
- Where
- Egypt
- Volunteers
- 70 people
- Sponsor
- Tanta University
Anterior Cruciate Ligament Injury, Anterior Cruciate Ligament Reconstruction
STABILITY 2: Anterior Cruciate Ligament Reconstruction +/- Lateral Tenodesis With Patellar vs Quad Tendon
Anterior cruciate ligament (ACL) rupture is one of the most common musculoskeletal injuries in young individuals, particularly those that are active in sports.
- Conditions
- Anterior Cruciate Ligament Injury, Anterior Cruciate Ligament Reconstruction, Joint Instability
- Trial name
- STABILITY 2 (NCT03935750)
- Testing
- Anterior cruciate ligament reconstruction (ACLR), Lateral extra-articular tenodesis (LET)
- Where
- 31 sites in United States, Canada and 6 more
- Volunteers
- 1,272 people
- Sponsor
- University of Pittsburgh
Anterior Cruciate Ligament Reconstruction
Anterior Cruciate Ligament (ACL) Reconstruction With Autologous Fat Pad Derived Mesenchymal Stem Cells
This study is designed as a prospective, open label, single arm pilot clinical study that will establish the safety and efficacy of a single injection of mesenchymal stromal cells in patients.
- Trial name
- NCT06798623
- Testing
- Autologous Mesenchymal Stromal Cells
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- The Methodist Hospital Research Institute
ACL Tear, ACL Injury
The Effect of Fertilized ACL Technique on Outcomes of ACL Reconstruction in Young Adults
A prospective study, with outcomes including re-rupture rate and return to sport will be collected following ACL reconstruction.
- Conditions
- ACL Tear, ACL Injury, Arthroscopy, Anterior Cruciate Ligament Tear
- Trial name
- FACL (NCT04178538)
- Testing
- ACL reconstruction with bone marrow, demineralized bone marix, and internal brace augmentation, Standard ACL reconstruction with all inside technique
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Marshall University
ACL - Anterior Cruciate Ligament Rupture, ACL Injuries
Non-Narcotic Pain Control After ACL Reconstruction
This is a double-blind randomized controlled trial of standard of care therapy, either oral ketorolac (experimental group) or oral oxycodone (control group) to demonstrate efficacy in reducing the percentage of narcotic doses…
- Trial name
- NCT06973785
- Testing
- dispense of study drug, Ketorolac
- Where
- 3 sites in United States
- Volunteers
- 30 people
- Sponsor
- The Cleveland Clinic
Anterior Cruciate Ligament Reconstruction Rehabilitation
Study on the Effects of Unilateral Resistance Training on Lower Limb Muscle Strength and Symmetry After Anterior Cruciate Ligament Reconstruction Surgery
Brief Summary Study type: Randomized controlled trial (interventional). Purpose: To find out whether six weeks of unilateral resistance training (URT) improves lower-limb strength and inter-limb symmetry more than traditional…
- Trial name
- NCT07271173
- Testing
- resistance training
- Where
- China
- Volunteers
- 48 people
- Sponsor
- Peking University Third Hospital
Anterior Cruciate Ligament Reconstruction
The Best Method for ACL Reconstruction.
The investigators wish to compare 3 methods for reconstruction of the anterior cruciate ligament using 3 different grafts: bone-patella tendon-bone, hamstrings and iliotibial tract graft, as these methods influence the muscles…
- Trial name
- NCT03192761
- Testing
- ACL reconstruction hamstrings, ACL reconstruction patella tendon, ACL reconstruction iliotibial tract
- Where
- Denmark
- Volunteers
- 90 people
- Sponsor
- Lars Konradsen
Anterior Cruciate Ligament Injury
Neuromuscular Profiles After Anterior Cruciate Ligament Reconstruction
The NEURO-ACL-ISOEMG study is an observational, cross-sectional, exploratory study conducted in patients between 4 and 12 months after anterior cruciate ligament (ACL) reconstruction.
- Trial name
- NEURO-ACL-ISOE (NCT07792863)
- Testing
- Neuromuscular and Patient-Reported Assessmen
- Where
- France
- Volunteers
- 30 people
- Sponsor
- Hopitaux de Saint-Maurice
Anterior Cruciate Ligament Reconstruction, Athrogenic Muscle Responses
The Effects of Cognitive Dual-Tasking in Later Stages of Rehabilitation After ACL Reconstruction
Anterior cruciate ligament (ACL) injuries are common in sports and often require a long and challenging rehabilitation process. Athletes who sustain these injuries typically engage in pivoting and cutting sports, where these…
- Conditions
- Anterior Cruciate Ligament Reconstruction, Athrogenic Muscle Responses, ACL Injury
- Trial name
- AMIRA (NCT06206200)
- Testing
- Cognitive dual task training (intervention group), Standard of care physiotherapy (control group)
- Where
- Belgium
- Volunteers
- 80 people
- Sponsor
- University Ghent
Anterior Cruciate Ligament Injuries, Anterior Cruciate Ligament Rupture
Reconstruction of the Anterior Cruciate Ligament of the Knee Joint, by the Method of Stabilization of the Screw With a Bioabsorbable Method, With or Without the Use of Autogenous Spongiform Bone Grafts.
Clinical and comparative evaluation of the results of autograft healing of the tendon of the semitendinus muscle in the tibial canal, after reconstruction of the anterior cruciate ligament of the knee joint, by the method of…
- Conditions
- Anterior Cruciate Ligament Injuries, Anterior Cruciate Ligament Rupture, Anterior Cruciate Ligament Tear, Knee Injuries
- Trial name
- NCT05328544
- Testing
- ACL reconstruction of the knee joint by arthroscopic technique, with the tibial fixation method using a bioabsorbable screw (Arthrex) with the use of autogenous cancellous bone grafts, ACL reconstruction of the knee joint by arthroscopic technique, with the tibial fixation method using a bioabsorbable screw (Arthrex) without the use of autogenous cancellous bone grafts
- Where
- Poland
- Volunteers
- 60 people
- Sponsor
- eMKa MED Medical Center
Sports Physical Therapy
Effects of Progressive Resistance Exercises Among Athletes With Hamstring Deficit After ACL Reconstruction
The goal of the study is to find out how mild home exercises (similar to usual care) and progressive strength training, which include neuromuscular exercise, affected knee joint function and HS muscle strength in individuals who…
- Trial name
- NCT06846164
- Testing
- Supervised progressive strength training including elements of neuromuscular exercise intervention (SNG), home based low-intensity weight-bearing exercise protocol.
- Where
- Pakistan
- Volunteers
- 20 people
- Sponsor
- Riphah International University
ACL Injury
Double-bundle Versus Single-Bundle Anterior Cruciate Ligament Reconstruction
The purpose of this study is to compare double-bundle and single-bundle techniques for ACL reconstruction in a long-term 15-year follow-up. Our hypothesis is that the DB technique is better than the SB technique.
- Trial name
- NCT06001164
- Testing
- ACL reconstruction: Double bundle, ACL reconstruction: Single bundle
- Where
- Finland
- Volunteers
- 153 people
- Sponsor
- Tampere University Hospital
Anterior Cruciate Ligament Rupture
Pain Management of ACL Reconstruction
This study will compare the outcome of pain interventions that are considered standard of care during the surgical treatment of ACL injuries.
- Trial name
- NCT03365908
- Testing
- Adductor Canal Nerve Block, Ropivacaine injection
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- University of California, Davis
Therapeutic Exercise, Physical Therapy Techniques
Exercise With Audible Cues on Motor Unit Behavior in Athletes With Anterior Cruciate Ligament Reconstruction
The closed kinetic chain (CKC) of terminal knee extension exercise (TKE) is designed to activate VM activity for knee injury training.
- Conditions
- Therapeutic Exercise, Physical Therapy Techniques, Neuromuscular Function
- Trial name
- ACLR (NCT06662955)
- Testing
- audible cues, Exercise
- Where
- Thailand
- Volunteers
- 40 people
- Sponsor
- Mahidol University
Ligament; Laxity, Knee, Anterior Cruciate Ligament Injury
Treatment of Anterior Ligament Rupture With Internal Brace Repair - A Prospective Randomised Controlled Study.
The purpose of this study is to determine whether anterior cruciate ligament injury in patients wishing to return to sports activities may be treated with repair supplemented with internal brace compared with a standard operation…
- Trial name
- NCT03800225
- Testing
- Repair
- Where
- Denmark
- Volunteers
- 4 people
- Sponsor
- Aarhus University Hospital
Anterior Cruciate Ligament Reconstruction
Gait-based Evaluation of Early Rehabilitation After ACL Reconstruction
The objective of this study is to evaluate the regaining of a normal gait within the early rehabilitation (12-13 weeks postsurgical) after reconstruction of the anterior cruciate ligament (ACL).
- Trial name
- NCT05481918
- Testing
- Home-based therapy after ACL reconstruction, Standardized ambulant therapy after ACL reconstruction
- Where
- 3 sites in Austria
- Volunteers
- 35 people
- Sponsor
- Karl Landsteiner University of Health Sciences
Anterior Cruciate Ligament Injuries, Muscle Weakness
Changes in the Force-velocity Relationship of Knee Muscles After ACL Reconstruction
Anterior cruciate ligament (ACL) tear is a frequent and devastating injury in sport, especially in pivoting-contact disciplines.
- Trial name
- FoVeA (NCT05712109)
- Testing
- Follow-up after Anterior cruciate ligament reconstruction
- Where
- France
- Volunteers
- 103 people
- Sponsor
- University Hospital, Caen
Anterior Cruciate Ligament Tear
Evaluation of Biocleanse Allografts For ACL Reconstruction
The purpose of this study is to determine the efficacy of patellar tendon allografts that have undergone the BioCleanse™ process.
- Trial name
- NCT00187876
- Testing
- ACL reconstruction control, ACL Biocleanse, surgical
- Where
- United States
- Volunteers
- 67 people
- Sponsor
- University of Florida