Clinical trials: AOD Effects and Consequences
AOD Effects and Consequences
Effect of Acute Ethanol Consumption on The Activity of Major Cytochrome P450 Enzymes, NAT2 and P-glycoprotein
Protocol title: Effect of acute alcohol consumption on the activity of major cytochrome P450 enzymes, NAT2 and P-glycoprotein. Objectives: The study is mainly conducted to evaluate the effect of acute alcohol consumption on the…
- Trial name
- NCT02515526
- Testing
- caffeine, tolbutamide, omeprazole, dextromethorphan, digoxin, midazolam single doses, ethanol multiple doses plus caffeine, tolbutamide, omeprazole, dextromethorphan, digoxin, midazolam single doses
- Where
- Germany
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- University of Cologne
AOD Effects and Consequences
Spectroscopic Imaging at 4T: A Drug Challenge Study
An advanced technique for rapid magnetic resonance proton spectroscopic imaging (1H-MRSI) will be employed in a drug challenge study in healthy volunteers to spatially map and measure acute changes in the brain chemicals GABA…
- Trial name
- CEBRA2 (NCT01577706)
- Testing
- Alprazolam, Dextroamphetamine
- Where
- United States
- Volunteers
- 7 people, healthy volunteers welcome
- Sponsor
- Mclean Hospital
AOD Effects and Consequences
Memantine in Bipolar Patients With Alcoholism
Since memantine may not only inhibit overactivity of microglial cell, but also repair the damaged neurons and neurogenesis through activation of astroglial cell and release of neurotrophic factors, the investigators propose that…
- Trial name
- NCT03043001
- Testing
- Memantine
- Where
- Taiwan
- Volunteers
- 60 people
- Sponsor
- National Cheng-Kung University Hospital