Clinical trials: ART Adherence
HIV Infections, Substance Use Disorders
Couples ART Adherence Intervention for PWID in Kazakhstan
The fastest growing HIV epidemics globally are driven by injection drug use, but only a small percentage of HIV-positive people who inject drugs (PWID) have achieved viral suppression.
- Trial name
- NCT03555396
- Testing
- SMART Couples 2, Standard of Care
- Where
- Kazakhstan
- Volunteers
- 132 people, healthy volunteers welcome
- Sponsor
- Columbia University
HIV-1-infection, Antenatal Care
An Integrated Strategy to Support Antiretroviral Therapy and Pre-exposure Prophylaxis Adherence for HIV Prevention in Pregnant and Breastfeeding Women
This study is composed of two parallel, pilot randomized groups that will obtain preliminary data about the the acceptability, fidelity, and clinical outcomes associated with a multi-component adherence support strategy for HIV…
- Trial name
- NCT04330989
- Testing
- iNSC and Adherence supporter training
- Where
- Malawi
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
HIV Infections, Contraception
Kuwa Free! - Live Free!
The study investigators are conducting foundational pharmacokinetic (PK) and qualitative studies, among 15-24 years old (inclusive) adolescent girls and young women living with HIV (AGYWLHIV) already on oral antiretroviral…
- Conditions
- HIV Infections, Contraception, Drug-drug Interaction
- Trial name
- NCT05044962
- Testing
- Cabotegravir/ Rilpivirine, Etonogestrel (ETG) implant, Intramuscular depo-medroxyprogesterone acetate (IM DMPA)
- Where
- Kenya
- Volunteers
- 700 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
HIV
Uptake and Adherence to Daily Oral PrEP as a Primary Prevention Strategy for Young African Women: A Vanguard Study
To assess the acceptance rate, adherence, acceptability, and continuation of oral pre-exposure prophylaxis (PrEP) among young southern African women.
- Trial name
- NCT02732730
- Testing
- Truvada, Drug level counseling at Weeks 8 and 13
- Where
- 3 sites in South Africa, Zimbabwe
- Volunteers
- 451 people, healthy volunteers welcome
- Sponsor
- HIV Prevention Trials Network
Adherence to Medication Regime
Early Antiretroviral Therapy and Pre-exposure Prophylaxis for HIV Prevention Among Female Sex Workers in Cotonou, Benin
In the last few years, early treatment of HIV-infected individuals, or "treatment as prevention (TasP), and pre-exposure prophylaxis with antiretroviral drugs among HIV-negative people at very high-risk of acquiring the infection…
- Trial name
- TasP/PrEP (NCT02237027)
- Testing
- TasP using ART regimen as per Benin guidelines, PrEP using Truvada
- Where
- Benin
- Volunteers
- 361 people, healthy volunteers welcome
- Sponsor
- CHU de Quebec-Universite Laval
HIV
Evaluating a Youth-Focused Economic Empowerment Approach to HIV Treatment Adherence
The goal of Suubi+Adherence is to examine the impact and cost associated with an innovative intervention to increase adherence to HIV treatment for HIV-infected adolescents.
- Trial name
- NCT01790373
- Testing
- Suubi+Adherence, Bolstered Standard of Care
- Where
- 2 sites in United States, Uganda
- Volunteers
- 702 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
HIV, Mental Health
NOLA GEM: Feasibility and Acceptability of an MHealth Intervention for Violence-affected PLWH
The objective of the proposed research is to conduct formative work to develop, pilot and refine a smartphone delivered intervention for violence affected people living with HIV utilizing a novel spatial-temporal methodology…
- Conditions
- HIV, Mental Health, Substance Use
- Trial name
- NCT05784714
- Testing
- NOLA GEM
- Where
- 4 sites in United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Tulane University
HIV-positive
Evaluation of the Impact of Mobile Phone Messages on ART and PMTCT Adherence in Mozambique
Mobile phone SMS are increasingly used to promote positive health behaviour with an aim to improve health outcomes. However, robust data on the efficacy of SMS on health seeking behaviour and patient outcomes in resource-limited…
- Trial name
- SMSaude (NCT01910493)
- Testing
- SMS reminders
- Where
- Mozambique
- Volunteers
- 1,352 people, healthy volunteers welcome
- Sponsor
- Absolute Return for Kids
HIV, Alcohol Use
Improving HIV and Alcohol-Related Outcomes Among HIV+ Persons in Clinic Settings
Alcohol use is increasingly recognized as a key factor in morbidity and mortality among HIV-positive individuals and represents an important public health concern, given its associations with medication non-adherence, increases…
- Conditions
- HIV, Alcohol Use, Medication Adherence
- Trial name
- PLUS (NCT02390908)
- Testing
- Immediate PLUS intervention, Wait-list PLUS intervention
- Where
- United States
- Volunteers
- 174 people, healthy volunteers welcome
- Sponsor
- Hunter College of City University of New York
HIV
Improving ART Retention and Adherence in Uganda: The WiseMama Study
WiseMama is designed to improve our understanding of interventions that are feasible and effective in helping HIV-positive pregnant and postpartum women to maintain high adherence to antiretroviral medications.
- Trial name
- WiseMama (NCT02396394)
- Testing
- Two-Step Adherence Feedback
- Where
- Uganda
- Volunteers
- 165 people, healthy volunteers welcome
- Sponsor
- Boston University
HIV (Human Immunodeficiency Virus)
Optimizing the Efficiency and Implementation of Cash Transfers to Improve Adherence to Antiretroviral Therapy Phase II
This protocol describes a 2-arm cluster, randomized controlled trial designed to test the effectiveness of a conditional cash transfer on viral suppression at 12 months post-ART initiation among PHWHIV who have initiated ART…
- Trial name
- Afya 2 Phase2 (NCT04201353)
- Testing
- Conditional Cash Transfer
- Where
- Tanzania
- Volunteers
- 1,984 people, healthy volunteers welcome
- Sponsor
- University of California, Berkeley
HIV Infections
Electronic Capture of Adherence Barriers for HIV Care
Adherence to antiretroviral therapy (ART) remains problematic. Our team has thus developed a new patient-reported measure of barriers to ART adherence (the I-Score) which will be completed by HIV patients through the Opal patient…
- Trial name
- CTNPT039 (NCT04702412)
- Testing
- The Opal patient portal and smartphone application combined with the I-Score patient-reported outcome measure
- Where
- Canada
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- McGill University Health Centre/Research Institute of the McGill University Health Centre