Clinical trials: ARTHROPLASTY, REPLACEMENT; ANESTHESIA
Arthroplasty, Replacement, Knee, Pain, Postoperative
BiFeS vs. iPACK in Postoperative Knee Arthroplasty Analgesia
The Biceps Femoris Short Head (BiFeS) block is a new fascial plane block technique targeting the sensory innervation of the posterolateral capsule of the knee while preserving motor function.
- Conditions
- Arthroplasty, Replacement, Knee, Pain, Postoperative, Anesthesia, Regional
- Trial name
- NCT07360392
- Testing
- Biceps Femoris Short Head Block (BiFeS), Infiltration Between The Popliteal Artery and The Capsule of The Knee, Adductor Canal Block
- Where
- Turkey (Türkiye)
- Volunteers
- 88 people
- Sponsor
- Amasya University
Spinal Anesthesia, Success or Failure of Spinal Anesthesia
The Influence of Body-mass Index on the Outcome of Spinal Anesthesia for Total Knee Replacement Arthroplasty
In these prospective observational study, the investigators are trying to evaluate (1) the influence of body-mass index on spinal anesthetic outcome and (2) the determinants on spinal anesthetic outcome by logistic regression…
- Trial name
- NCT01609517
- Testing
- Spinal anesthesia (heavy bupivacaine)
- Where
- South Korea
- Volunteers
- 209 people
- Sponsor
- Samsung Medical Center
Regional Anesthesia, Hip Arthroplasty
SFIB vs PENG Block in the Anesthesia for Total Hip Replacement
Total hip replacement is one of the most common orthopedic operations. According to statistical studies, more than 1 million of such surgical interventions are performed annually in the world.
- Trial name
- NCT07061223
- Testing
- SFIB, PENG block, Patient control analgesia
- Where
- Russia
- Volunteers
- 120 people
- Sponsor
- State Budgetary Healthcare Institution, National Medical Surgical Center N.A. N.I. Pirogov, Ministry of Health of Russia
Anesthesia, Conduction, Arthroplasty, Replacement, Knee
Inter-fascial Plane Between the SArtorius Muscle and FEmoral Artery (ISAFE)
Total knee arthroplasty (TKA) is a frequent performed surgery. Adequate pain management is an important feature. Analgesic duration of single shot nerve blocks is limited to no more than 24h.
- Trial name
- ISAFE (NCT05313269)
- Testing
- ISAFE technique for adductor canal catheter insertion, Conventional technique for adductor canal catheter insertion
- Where
- Canada
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Knee Replacement Surgery
The Effect of Nasal Continuous Positive Airway Pressure (N-CPAP) on Arterial pCO2 During Spinal Anesthesia
The proposed study intends to investigate several aspects of the respiratory effects of intravenous sedation of patients undergoing spinal anesthesia for knee replacement surgery.
- Trial name
- NCT01622647
- Testing
- Nasal Continuous Positive Airway Pressure (NCPAP)
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Pediatrix
Knee Arthroplasty
Continuous Femoral Nerve Blockade and Readiness to Discharge Following Total Knee Arthroplasty
Patients undergoing total knee arthroscopy (knee replacement) surgery usually receive a femoral nerve block as part of their anesthetic care.
- Trial name
- NCT00803348
- Testing
- Bolus of 0.2% ropivicaine 20 mls followed by 0.2% ropivicaine at an infusion rate of 5mls/hr until 0600 on postoperative day 2, Bolus of 0.2% ropivicaine 20 mls followed by 0.1% ropivicaine at an infusion rate of 10mls/hr until 0600 on post-operative day 2, Saline control
- Where
- Canada
- Volunteers
- 99 people
- Sponsor
- University Health Network, Toronto
Anesthesia, Conduction, Pain, Postoperative
Combined PENG and LFCN Block for Total Hip Arthroplasty
A clinical trial investigating the effect of a combined locoregional anesthesia technique on the postoperative analgesia outcomes after a total hip arthroplasty. A PENG block will be used in combination with a LFCN block.
- Conditions
- Anesthesia, Conduction, Pain, Postoperative, Arthroplasty, Replacement, Hip
- Trial name
- NCT04996290
- Testing
- PENG + LFCN block, Ropivacaine injection
- Where
- Belgium
- Volunteers
- 40 people
- Sponsor
- University Hospital, Antwerp
Knee Replacement, Total, Pain, Postoperative
Two Different Blocks for Postoperative Analgesia in Patients Undergoing Unilateral Total Knee Arthroplasty
The frequency of femoral nerve block and adductor canal block for analgesia after TKA(total knee arthroplasty) increases with the use of ultrasonography in regional anesthesia.
- Conditions
- Knee Replacement, Total, Pain, Postoperative, Anesthesia, Regional
- Trial name
- NCT04286035
- Testing
- Bupivacaine Injection
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Sisli Hamidiye Etfal Training and Research Hospital
Shoulder Arthroplasty
Interscalene Block With Liposomal Bupivacaine vs. Interscalene Block With Bupivacaine and Adjuvants
The purpose of this study is to determine whether the use of plain bupivacaine with common adjuvants for interscalene block (ISB) provides non-inferior analgesic results compared to the use of liposomal bupivacaine for ISB, in…
- Trial name
- NCT03845894
- Testing
- Liposomal bupivacaine, Bupivacaine with adjuvants
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Wake Forest University Health Sciences
Acute Pain, Regional Anesthesia Morbidity
A Trial Comparing Adductor Canal Catheter and Intraarticular Catheter Following Primary Total Knee Arthroplasty
The study is a prospective randomized controlled trial comparing intraarticular catheters and adductor canal catheters for postoperative analgesia following a primary Total Knee Arthroplasty (TKA).
- Trial name
- NCT02497911
- Testing
- Adductor Canal Catheter, Intraarticular Catheter, Ropivicaine
- Volunteers
- 110 people
- Sponsor
- Thomas Jefferson University
Spinal Anesthesia, Total Knee Replacement Arthroplasty
ED50 and ED95 of Intrathecal Bupivacaine With or Without Epinephrine for Total Knee Replacement Arthroplasty
This prospective randomized double-blind dose-response study is aimed to investigate the ED50 and ED95 of intrathecal bupivacaine with or without epinephrine 100 mcg for total knee replacement arthroplasty.
- Trial name
- NCT01264575
- Testing
- intrathecal bupivacaine 6 mg with 100 mcg of epinephrine, intrathecal bupivacaine 7 mg with 100 mcg of epinephrine, intrathecal bupivacaine 8 mg with 100 mcg of epinephrine
- Where
- South Korea
- Volunteers
- 162 people
- Sponsor
- Seoul Medical Center
Total Knee Replacement Surgery
Postoperative Pain in Total Knee Arthroplasty: a Comparison Between General and Spinal Anesthesia
Total knee arthroplasty may be conducted either under general anesthesia or spinal block. previous studies have shown that spinal block leads to less complications.
- Trial name
- NCT03176758
- Testing
- Spinal Block, General anesthetic, Total knee replacement
- Volunteers
- 60 people
- Sponsor
- Meir Medical Center
Total Knee Replacement
The Analgesic Efficacy of Local Anaesthetic Wound Infiltration Versus Intrathecal Morphine for Total Knee Replacement
Total knee replacement (TKR) is associated postoperatively with considerable pain and analgesic requirement. Total knee replacement is routinely performed under spinal anaesthesia with intrathecal bupivacaine plus preservative…
- Trial name
- NCT01312415
- Testing
- Levobupivacaine, Intrathecal morphine
- Where
- Ireland
- Volunteers
- 42 people
- Sponsor
- Cork University Hospital
Arthroplasty, Replacement, Knee, Pain, Postoperative
GENIVS Block Versus Adductor Canal Block After Total Knee Arthroplasty
The goal of this clinical trial is to learn whether the ultrasound-guided GENIVS block is not worse than (non-inferior to) the adductor canal block in reducing opioid use after total knee arthroplasty performed under spinal…
- Conditions
- Arthroplasty, Replacement, Knee, Pain, Postoperative, Osteoarthritis, Knee
- Trial name
- GENIVS-ACB (NCT07901348)
- Testing
- GENIVS block, Adductor Canal Block (ACB) Only
- Where
- Turkey (Türkiye)
- Volunteers
- 74 people
- Sponsor
- Bakirkoy Dr. Sadi Konuk Research and Training Hospital
Postoperative Delirium, Anesthesia
The Effect of 40 Hz Transcranial Stimulation on the Incidence of Delirium After Total Hip Replacement or Total Knee Replacement Arthroplasty in Elderly Patients.
Delirium is an acute confusional state, it is a sign of acute encephalopathy, also known as acute brain failure, acute brain dysfunction or mental state changes.Postoperative delirium can cause post-traumatic stress disorder…
- Conditions
- Postoperative Delirium, Anesthesia, Elderly
- Trial name
- NCT06522087
- Testing
- 40Hz stimulation
- Where
- China
- Volunteers
- 110 people
- Sponsor
- Henan Provincial People's Hospital
Pain Management
Adductor Canal Block After Total Knee Replacement - a Suture-method Catheter vs a Standard Catheter vs a Single Bolus
In this study we wish to investigate the analgesic effect of the administration of 0.2% ropivacaine for an adductor canal block as repeated boluses (20 ml every 8 hours) through a new suture-method catheter or a standard…
- Trial name
- NCT03142789
- Testing
- Initial bolus (Certa and standard catheter groups), Initial bolus (Single bolus group), Intermittent boluses (Certa and standard catheter groups)
- Where
- Denmark
- Volunteers
- 153 people
- Sponsor
- University Hospital, Gentofte, Copenhagen
Arthroplasty, Replacement, Hip, Knee
Enhanced Recovery After Surgery (ERAS) Pathway for Primary Hip and Knee Arthroplasty
As the world goes into the aging society, the number of total hip and total knee arthroplasty (THA and TKA) will increase fast. It's important to develop strategies to improve the quality of healthcare and get earlier recovery…
- Trial name
- NCT03517098
- Testing
- The ERAS group, The non-ERAS group
- Where
- China
- Volunteers
- 640 people
- Sponsor
- West China Hospital
Arthroplasty, Replacement, Hip, Fascia Iliaca Block
Ultrasound Guided Fascia Iliaca Block for Pain Control After Elective Hip Replacement Surgery
The purpose of this study is to determine whether ultrasound guided fascia iliaca blocks performed before surgery help to reduce pain after elective total hip replacements.
- Trial name
- NCT02108847
- Testing
- .2% Ropivacaine, Saline, Fascia Iliaca Block
- Where
- Canada
- Volunteers
- 42 people
- Sponsor
- University of Saskatchewan
Arthroplasty, Replacement, Hip
Low Concentration Local Anesthesia Fascia Iliaca Block for Total Hip Arthroplasty
Fascia iliaca compartment block (FICB) is a documented option for postoperative analgesia for total hip arthroplasty (THA) surgery.
- Trial name
- HALF (NCT06102811)
- Testing
- Low Concentration Local Anesthetic Fascia Iliaca Compartment Block, High Concentration Local Anesthetic Fascia Iliaca Compartment Block
- Where
- Canada
- Volunteers
- 60 people
- Sponsor
- University of Toronto
Osteoarthritis (Knee / Hip), Sarcopenia
Preoperative Muscle Stiffness, Functional Reserve, and Postoperative Quality of Recovery in Lower Extremity Arthroplasty
In elderly patients undergoing arthroplasty surgery, postoperative recovery quality is closely related to preoperative physical reserve. Sarcopenia and reduced muscle quality can increase postoperative complications.
- Conditions
- Osteoarthritis (Knee / Hip), Sarcopenia, Postoperative Recovery
- Trial name
- PRE-QoR (NCT07879209)
- Testing
- Handgrip Strength (HGS) Measurement, Ultrasound Shear Wave Elastography (SWE)
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Ankara Etlik City Hospital