Clinical trials: ASD, Anxiety
Anxiety, Attention Deficit Hyperactivity Disorder (ADHD)
Pilot Trial of a Social Skills Group Treatment (Secret Agent Society Program)
Several independent evaluations have supported the effectiveness of the Secret Agent Society (SAS) Program in improving the social-emotional functioning of children with Autism Spectrum Disorders (ASD) in clinic- (Beaumont \&…
- Conditions
- Anxiety, Attention Deficit Hyperactivity Disorder (ADHD), Autistic Spectrum Disorder (ASD)
- Trial name
- NCT02574273
- Testing
- Secret Agent Society (SAS) Program, Waitlist Group / Treatment As Usual
- Where
- United States
- Volunteers
- 106 people
- Sponsor
- Weill Medical College of Cornell University
Autism Spectrum Disorder, Parenting Stress
Feasibility and Acceptability of Laughter Yoga in Children With Autism Spectrum Disorder and Their Parents
This is a pilot randomised controlled trial to explore the acceptability and feasibility of laughter yoga about anxiety and depression reduction in children with ASD and parenting stress reduction for their parents.
- Conditions
- Autism Spectrum Disorder, Parenting Stress, Depression, Anxiety
- Trial name
- NCT06326255
- Testing
- laughter yoga
- Where
- Hong Kong
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- LAM Chung Yan Hemio
Autism Spectrum Disorder, Anxiety
CBT for Anxiety in Children With Autism
This is a randomized controlled trial of Cognitive Behavioral Therapy (CBT) versus Psychoeducation and Supportive Therapy (PST) in children with Autism Spectrum Disorder and moderate to severe anxiety.
- Trial name
- NCT02725619
- Testing
- CBT, PST
- Where
- United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Yale University
Anxiety Disorders in Youth With Autism, Asperger's Syndrome, and Pervasive Developmental Disorder Not Otherwise Specified
Cognitive Behavioral Therapy (CBT) for Anxiety Disorders in Autism: Adapting Treatment for Adolescents
Comorbid anxiety disorders affect as many as 80% of youth with autism spectrum disorders, causing substantial distress and impairment over and above the autism spectrum diagnosis alone.
- Trial name
- NCT01177969
- Testing
- Cognitive-Behavioral Therapy, Wait-list
- Where
- 2 sites in United States
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- University of South Florida
Autistic Spectrum Disorder, Constipation
Oral Administration of Polyethylene Glycol (PEG) for 6 Months in Chronically Constipated Autistic Children
Many autistic children suffer from chronic constipation. Gut mobilization was obtained administering polyethylene glycol (PEG) at the dose of 6.9 g/d once a day for 6 months in an open trial involving 21 chronically constipated…
- Trial name
- NCT05025553
- Testing
- Gut mobilization
- Where
- Italy
- Volunteers
- 21 people
- Sponsor
- University of Messina
Autism Spectrum Disorder, Anxiety
taVNS for Anxiety in ASD
Investigators will recruit up to 10 patients with Anxiety comorbid with Autism Spectrum Disorder (ASD) from the outpatient clinics at MUSC.
- Trial name
- NCT06258590
- Testing
- Transcutaneous auricular vagus nerve stimulation
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Medical University of South Carolina
Obsessive-Compulsive Disorder
An eHealth Intervention for Obsessive Compulsive Disorder in Youth With Autism Spectrum Disorder
This study is a feasibility study of Internet-delivered CBT for OCD in children and adolescents (7-17 years) with comorbid Autism Spectrum Disorder.
- Trial name
- NCT03473080
- Testing
- Internet CBT
- Where
- Sweden
- Volunteers
- 22 people
- Sponsor
- Karolinska Institutet
Autism
Sensory Adapted Dental Environment to Enhance Oral Care for Children With ASD
The goal of this project is to collect information that will support a later clinical trial on the effectiveness of a specially adapted dental environment for children who have difficulty tolerating oral care in the dental…
- Trial name
- SADE (NCT02077985)
- Testing
- Sensory Adapted Dental Environment
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- University of Southern California
Autism Spectrum Disorder, Neurodevelopmental Disorders
KneuroKnits: Participation and Anxiety in People With Neurological Conditions Participating in a Knitting Group
The reported social benefits of knitting combined with the urgent need for social and activity-based programs in the disability community suggest that a knitting intervention may fill a substantial gap in available programs.
- Conditions
- Autism Spectrum Disorder, Neurodevelopmental Disorders, Acquired Brain Injury, Physical Disability
- Trial name
- NCT04639570
- Testing
- KneuroKnits
- Where
- Canada
- Volunteers
- 14 people
- Sponsor
- Holland Bloorview Kids Rehabilitation Hospital
Autism
Treatment for Children With Autism and Anxiety
Children with high-functioning autism spectrum disorders (ASD) are at high risk for developing significant anxiety symptoms. Cognitive behavior therapies (CBT) are frequently used for children with anxiety symptoms with good…
- Trial name
- NCT01727466
- Testing
- Facing Your Fears
- Volunteers
- 50 people
- Sponsor
- University of Colorado, Denver
Autism Spectrum Disorders, Anxiety
Probiotics for Quality of Life in Autism Spectrum Disorders
A randomized pilot trial of a probiotic for quality of life in autism spectrum disorder (ASD), targeting gastrointestinal (GI) symptoms.
- Trial name
- NCT02903030
- Testing
- Visbiome Extra Strength
- Where
- United States
- Volunteers
- 13 people
- Sponsor
- Ohio State University
Adenovirus, Anesthesia
Pharmacokinetics of Understudied Drugs Administered to Children Per Standard of Care
Understudied drugs will be administered to children per standard of care as prescribed by their treating caregiver and only biological sample collection during the time of drug administration will be involved.
- Conditions
- Adenovirus, Anesthesia, Anxiety, Anxiolysis
- Trial name
- PTN_POPS (NCT01431326)
- Testing
- The POPS study is collecting PK data on children prescribed the following drugs of interest per standard of care:
- Where
- 52 sites in United States, Canada and 3 more
- Volunteers
- 3,520 people
- Sponsor
- Daniel Benjamin
Bi-Polar Disorder, Autism Spectrum Disorder (ASD)
An Examination of the Performance of QbMobile in Differential Diagnosis Associated With ADHD Symptoms
The purpose of this study is to evaluate QbMobile's ability to collect objective data to identify specific symptom profiles in differential diagnoses (ASD, MDD, Bipolar Disorder and Anxiety Disorder) that are common with ADHD.
- Conditions
- Bi-Polar Disorder, Autism Spectrum Disorder (ASD), Major Depression Disorders, Separation Anxiety Disorder
- Trial name
- NCT07329673
- Testing
- Digital software application for cognitive performance and activity measurement (QbMobile, investigational device)
- Where
- United States
- Volunteers
- 300 people
- Sponsor
- Qbtech AB
Autism Spectrum Disorder
Intranasal Oxytocin for the Treatment of Children and Adolescents With Autism Spectrum Disorders (ASD)
We are studying an investigational drug called intranasal oxytocin (Syntocinon®). Syntocinon® has been approved by the U.S. Food and Drug Administration for use in helping women breastfeed, but it has not been approved for use in…
- Trial name
- OXY-R (NCT01908205)
- Testing
- Intranasal Oxytocin
- Where
- 2 sites in United States, Canada
- Volunteers
- 60 people
- Sponsor
- Holland Bloorview Kids Rehabilitation Hospital
Autism Spectrum Disorder, Physical Activity
Gamified App on Increasing Physical Activity and Reducing Anxiety in Autism
Background: Physical activity (PA) has an impact on physical and mental health in neurotypical populations, and addressing these variables may improve the prevalent burden of anxiety in adults with autism spectrum disorder (ASD).
- Conditions
- Autism Spectrum Disorder, Physical Activity, Anxiety, Mobile Health
- Trial name
- NCT05466617
- Testing
- Mobile Health for Physical Activity Behavior Change
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Indiana University
Autism, Autism Spectrum Disorder
Autism Genomics Sweden - Genetic Guidance and Information Trial
This observational clinical trial aims to evaluate whether providing genetic information about the origins of autism and related psychiatric disorders enhances understanding, well-being, and empowerment in adolescents and young…
- Conditions
- Autism, Autism Spectrum Disorder, ADHD - Attention Deficit Disorder With Hyperactivity, Depression Anxiety Disorder
- Trial name
- AuGeS-GV (NCT06740760)
- Testing
- Genetic counselling, Leaflet
- Where
- Sweden
- Volunteers
- 63 people
- Sponsor
- Karolinska Institutet
Autism, Autism Spectrum Disorder
Coaching Children With Anxiety and Autism Through Telehealth
This study will examine a telehealth parenting intervention to reduce anxiety in 20 families of children between 4 and 8 years old with autism and anxiety. Caregivers and children complete 12 telehealth treatment sessions.
- Conditions
- Autism, Autism Spectrum Disorder, Anxiety
- Trial name
- CAT (NCT05588570)
- Testing
- CAT
- Where
- United States
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- Medical University of South Carolina
Autism Spectrum Disorder, Social Stories
Effect of Social Stories on Anesthesia Compliance in Children With Autism
Children with Autism Spectrum Disorder (ASD) frequently experience heightened anxiety and reduced cooperation during the perioperative period, which can complicate anesthesia induction and negatively affect procedural safety and…
- Trial name
- NCT07356895
- Testing
- Social Stories Group, Routine Preoperative Preparation Group
- Where
- Turkey (Türkiye)
- Volunteers
- 44 people
- Sponsor
- Diskapi Yildirim Beyazit Education and Research Hospital
Anxiety, Autism Spectrum Disorder
The Effect of Aroma on Anxiety Among Children With Autism.
This study evaluates the effects of essential oils on anxiety scores among children who have an autism spectrum disorder. One third of the children will receive a control blend of oils, one third of the children will receive a…
- Trial name
- NCT03489811
- Testing
- Test Essential Oil Blend, Active Essential Oil Blend, Control Blend
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Nutraceuticals Research Institute
Autistic Spectrum Disorder, Anxiety Disorders
Feasibility Study of UP-A-AST Parent Group for Adolescents With Autism and Co-occurring Anxiety/Depression
Autism spectrum disorder (ASD) is associated with high rates of psychiatric comorbidity, particularly anxiety and depressive disorders, which contribute to significant impairment for affected youth and their families.
- Conditions
- Autistic Spectrum Disorder, Anxiety Disorders, Depressive Disorder
- Trial name
- NCT07637799
- Testing
- Unified Protocol-Adolescent Autism Parent Group (UP-A-AST)
- Where
- Sweden
- Volunteers
- 72 people
- Sponsor
- Sahlgrenska University Hospital