Clinical trials: ATRIAL FLUTTER
Atrial Flutter, Radiofrequency Catheter Ablation
Randomised Prospective Trial Comparing Contact Force and Non-contact Force Guided Catheter Ablation for Cavotricuspid Isthmus Dependent Atrial Flutter
Radiofrequency ablation (RFA) is a standard treatment option for cavotricuspid isthmus (CTI) dependent atrial flutter. We plan to perform a randomized prospective trial comparing the efficacy of contact force (CF) guided CTI…
- Trial name
- NCT02825498
- Testing
- Contact force guided RFA
- Where
- Canada
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Victoria Cardiac Arrhythmia Trials
Atrial Fibrillation, Atrial Flutter
Cardiovascular Registry of Atrial Fibrillation
Follow a representative sample of Latin American patients diagnosed with atrial fibrillation to set data on demographic characteristics, documenting antithrombotic therapy, describe the INR control level of VKA users…
- Trial name
- LACROSS (NCT04456842)
- Testing
- Patient Registry Data
- Where
- 17 sites in Argentina, Brazil and 2 more
- Volunteers
- 2,016 people
- Sponsor
- Brazilian Clinical Research Institute
Atrial Fibrillation, Atrial Flutter
Potassium Infusion for Conversion of Atrial Fibrillation/-Flutter
Atrial fibrillation is a condition in which the heart's upper chambers, the atria, contract at an abnormally rapid rate. It is a common type of arrhythmia, and occurs in 1-2% of the general population.
- Trial name
- NCT01818583
- Testing
- Potassium chloride, Glucose 50 MG/ML
- Where
- Norway
- Volunteers
- 143 people
- Sponsor
- Diakonhjemmet Hospital
Atrial Fibrillation or Atrial Flutter
Multipolar Mapping and Atrial Arrhythmias
This clinical investigation utilizes the Constellation Full Contact Mapping catheter in the left and right atria to explore atrial signal characteristics that can guide atrial fibrillation and atrial flutter ablation procedures…
- Trial name
- NCT02307188
- Testing
- Constellation Full Contact Mapping Catheter
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- Angelo Biviano
Tachycardia Atrial, Atrial Fibrillation
Comparing Magnesium 2g Versus 4g Versus Placebo in the Incidence of Treating AFF RVR
The purpose of this prospective, randomized, double-blinded study is to further evaluate the safety and efficacy of varying doses of intravenous magnesium in the treatment of AFF RVR.
- Conditions
- Tachycardia Atrial, Atrial Fibrillation, Atrial Flutter With Rapid Ventricular Response
- Trial name
- ATRIUM (NCT06376916)
- Testing
- Magnesium Sulfate 2 G, Magnesium Sulfate 4 G, Saline
- Where
- United States
- Volunteers
- 153 people
- Sponsor
- Wake Forest University Health Sciences
Atrial Fibrillation
Usefulness of Markers to Predict Recurrence of Atrial Fibrillation After Radiofrequency Catheter Ablation
Catheter ablation using radiofrequency is a new therapeutic tool to treat atrial fibrillation with a higher success rate than medical therapy (80% versus less than 50% respectively).
- Trial name
- NCT00315068
- Where
- Switzerland
- Volunteers
- 180 people
- Sponsor
- University Hospital, Geneva
Atrial Fibrillation and Flutter, Stroke
The Danish Warfarin-Dialysis Study - Safety and Efficacy of Warfarin in Patients With Atrial Fibrillation on Dialysis
The study aims to evaluate the appropriateness of initiating oral anticoagulation for stroke risk reduction in dialysis populations with atrial fibrillation.
- Conditions
- Atrial Fibrillation and Flutter, Stroke, Major Bleed, End-stage Renal Disease
- Trial name
- DANWARD (NCT03862859)
- Testing
- Warfarin
- Where
- 13 sites in Denmark
- Volunteers
- 718 people
- Sponsor
- Nicholas Carlson
Atrial Fibrillation, Atrial Tachycardia
Stanford Cardiac Invasive Electrophysiology Novel Computer Experience
This study will test the ability of computer algorithms to predict successful ablation therapy for atrial arrhythmias.
- Conditions
- Atrial Fibrillation, Atrial Tachycardia, Atrial Flutter, Arrhythmias, Cardiac
- Trial name
- SCIENCE (NCT03549806)
- Testing
- No Intervention. Test is computer algorithm.
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- Stanford University
Atrial Fibrillation, Atrial Flutter
Feasibility Study on the VERAFEYE Imaging and Navigation System for Guided Catheter Ablation Procedures
The objective of the study is to collect data on the usability and integration of the VERAFEYE Imaging and Guidance System in adult patients indicated to undergo a standard of care catheter-based ablation procedure for the…
- Conditions
- Atrial Fibrillation, Atrial Flutter, Atrial Arrhythmia
- Trial name
- INSiGHT (NCT07271238)
- Testing
- VERAFEYE Imaging and Guidance System
- Where
- Croatia
- Volunteers
- 50 people
- Sponsor
- LUMA Vision Ltd.
Atrial Flutter
Half-normal Saline in Atrial Flutter Ablation
To assess the acute and long-term efficacy of half-normal saline compared to normal saline for irrigation of open-irrigated catheters during catheter ablation for the treatment of cavotricuspid isthmus dependent atrial flutter.
- Trial name
- NCT04001530
- Testing
- Half Normal Saline 0.45% Infusion Solution Bag, Normal Saline 0.9% Infusion Solution Bag
- Where
- Canada
- Volunteers
- 4 people
- Sponsor
- Sunnybrook Health Sciences Centre
Atrial Fibrillation, Paroxysmal or Persistent, Atrial Fibrillation and Flutter
Versatility of a Circular Multielectrode Catheter in the Individualized Recognition & Treatment of Atrial Fibrillation and Related Arrhythmias Using Pulsed Field Energy
The purpose of this pragmatic study is to evaluate the safety, performance and effectiveness of the VARIPULSE catheter technology used in combination with the TRUPULSE™ Generator, and the compatible EAM system (Carto 3D) to treat…
- Conditions
- Atrial Fibrillation, Paroxysmal or Persistent, Atrial Fibrillation and Flutter, Atrial Flutter Typical
- Trial name
- VIRTUE (NCT06056557)
- Testing
- VARIPULSE™ catheter ablation
- Where
- United States
- Volunteers
- 141 people
- Sponsor
- Vivek Reddy
Acute Coronary Syndrome, Myocardial Infarction
What is the Optimal Antithrombotic Strategy in Patients With Atrial Fibrillation Undergoing PCI?
The optimal antithrombotic management in patients with coronary artery disease (CAD) and concomitant atrial fibrillation (AF) is unknown.
- Conditions
- Acute Coronary Syndrome, Myocardial Infarction, Atrial Fibrillation, Atrial Flutter
- Trial name
- WOEST-3 (NCT04436978)
- Testing
- 30-day DAPT, Guideline-directed therapy
- Where
- 20 sites in Belgium, Netherlands
- Volunteers
- 2,000 people
- Sponsor
- St. Antonius Hospital
Atrial Fibrillation (AF), Atrial Flutter
Detection of Atrial Fibrillation Through Voice Signal Processing
This study is testing a new technology that listens to a person's voice during short phone calls to help identify heart rhythm problems.
- Trial name
- NCT07212816
- Testing
- Sauti
- Volunteers
- 40 people
- Sponsor
- Vital Audio Inc
Atrial Fibrillation, Atrial Flutter
An Initial Assessment of the Sphere-9™ Catheter and Affera Mapping and Ablation System
A prospective, single-arm, multi-center, safety and performance assessment of the Sphere-9™ Catheter and the Affera Mapping and Ablation System to treat Atrial Arrhythmias
- Trial name
- NCT04210622
- Testing
- Catheter mapping and ablation with the Sphere-9 Catheter and Affera Mapping and Ablation System
- Where
- Lithuania
- Volunteers
- 16 people
- Sponsor
- Medtronic Cardiac Ablation Solutions
Rhythm Monitoring
Cardiac Magnetic Resonance Predictors of Outcome of Rhythm Control in Patients with Atrial Fibrillation/Flutter
evaluate the impact of various features in CMR on the mid-term/long-term success rate of rhythm control for paroxysmal atrial fibrillation/flutter .
- Trial name
- NCT06758895
- Where
- Egypt
- Volunteers
- 90 people
- Sponsor
- Assiut University
Postoperative Atrial Fibrillation
Rate Control Versus Rhythm Control For Postoperative Atrial Fibrillation
The purpose of this study is to compare the therapeutic strategies of rate control versus rhythm control in cardiac surgery patients who develop in-hospital postoperative atrial fibrillation or atrial flutter (AF).
- Trial name
- NCT02132767
- Testing
- Amiodarone, DC-cardioversion, Rate Control
- Where
- 23 sites in United States, Canada
- Volunteers
- 523 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Atrial Fibrillation, Atrial Flutter
iPhone Helping Evaluate Atrial Fibrillation Rhythm Through Technology
Atrial fibrillation (AF), a condition where the top chambers of the heart beat irregularly, is a major health problem. The long-term goal of this project is to use a personal, mobile heart monitor to help patients better…
- Trial name
- iHEART (NCT02731326)
- Testing
- AliveCor, Behavioral Altering Messaging
- Where
- United States
- Volunteers
- 264 people
- Sponsor
- Columbia University
Atrial Flutter
Antero-posterior Versus Antero-lateral Electrode Position for Electrical Cardioversion of Typical Atrial Flutter
The aim of this study is to identify the one electrode position out of two most commonly used for external electrical cardioversion of typical atrial flutter, which needs less delivered energy and less needed number of shocks for…
- Trial name
- APOVERSAL (NCT00860314)
- Testing
- external electrical cardioversion (with antero-posterior electrode position), external electrical cardioversion (with antero-lateral electrode position)
- Where
- Germany
- Volunteers
- 96 people
- Sponsor
- Universitätsklinikum Hamburg-Eppendorf
Atypical Atrial Flutter, Atrial Flutter
Pulsed-Field Ablation for Recurrent Atypical Atrial Flutter
Recurrent atypical atrial flutter (AFL) after prior atrial fibrillation or flutter ablation remains challenging to treat, and conventional radiofrequency ablation may be limited by incomplete lesion formation and risk of…
- Trial name
- NCT07362134
- Testing
- Point-by-point pulsed-field catheter ablation
- Where
- Taiwan
- Volunteers
- 30 people
- Sponsor
- Taipei Veterans General Hospital, Taiwan
Heart Failure With Reduced Ejection Fraction, Heart Failure With Preserved Ejection Fraction
Study of JK07 in Patients With Chronic Heart Failure
This is a Phase 2, randomized, double-blind, placebo-controlled, multiple dose study to assess the safety, tolerability, and efficacy of JK07 in participants aged 18-85 with heart failure.
- Trial name
- RENEU-HF (NCT06369298)
- Testing
- JK07
- Where
- 62 sites in United States, Canada and 2 more
- Volunteers
- 282 people
- Sponsor
- Salubris Biotherapeutics Inc