Clinical trials: Abdomen Disease
Acute Appendicitis
Variation in Acute Appendicitis During COVID-19 Pandemic in Italy
retrospective observational study of variation in incidence and clinical presentation of appendicitis during the pandemic in northern Italy, compared with the same period in the previous 2 years.
- Trial name
- NCT04649996
- Testing
- Appendectomy
- Where
- 6 sites in Italy
- Volunteers
- 532 people
- Sponsor
- University of Milano Bicocca
Obesity, Insulin Resistance
Weight Loss and Abdominal Fat Responses to Different Diet Compositions
The purpose of this study is to assess the effectiveness of two different reduced calorie diets that have different combinations of carbohydrate, fat, and protein content in 2 groups of study participants: insulin sensitive…
- Conditions
- Obesity, Insulin Resistance, Metabolic Syndrome
- Trial name
- NCT01034046
- Testing
- Low Carbohydrate Diet, Low Fat Diet
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- University of Nevada, Las Vegas
Acute Appendicitis
Inflammatory Parameters as Predictive Factors for Complicated Appendicitis
Acute appendicitis is a major cause of acute abdomen. Although its diagnosis is clinical, it is often supported by complementary diagnostic tests.
- Trial name
- NCT05116124
- Testing
- dosing of inflammatory parameters
- Volunteers
- 841 people
- Sponsor
- Centro Hospitalar do Tâmega e Sousa
Dyspnea, Healthy Volunteers
Effects on Experimental Dyspnea of High Flow Nasal Cannula
To develop an experimental model of dyspnea by external thoraco-abdominal elastic strapping at rest in order to study the mechanisms involved in the relief of dyspnea by the administration of high flow by nasal cannula (HFNC).
- Trial name
- EDEN (NCT03469037)
- Testing
- Optiflow with an inspired fraction of oxygen of 100%, Optiflow with an inspired fraction of oxygen of 21%
- Where
- 2 sites in France
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Association pour le Développement et l'Organisation de la Recherche en Pneumologie et sur le Sommeil
Pulmonary Cancer, Breast Neoplasms
18F-FSPG PET/CT Imaging in Patients With Cancers
This study aims to compare the diagnostic performance of 18F-FDG and 18F-FSPG PET/CT in lung, breast, and abdominal cancers before undergoing therapy.
- Conditions
- Pulmonary Cancer, Breast Neoplasms, Abdominal Cancer
- Trial name
- NCT03144622
- Where
- Taiwan
- Volunteers
- 120 people
- Sponsor
- National Taiwan University Hospital
Hypoventilation, Hypoxemia
Postoperative Respiratory and Activity Monitoring
This study plans to learn more about specific breathing and activity recommendations for patients after surgery. Participants will be monitored after abdominal surgery to identify what activities help them breathe better and…
- Conditions
- Hypoventilation, Hypoxemia, Postoperative Pulmonary Complications
- Trial name
- NCT06239831
- Testing
- ExSpiron and ActivPAL Monitors
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- University of Colorado, Denver
Ovarian Neoplasms, Fallopian Tube Neoplasms
OVCA-NAC-P2: Study of Chemotherapy Followed by Cytoreductive Surgery for Ovarian, Tubal and Peritoneal Cancers: JCOG0206
A feasibility study of neoadjuvant chemotherapy (NAC) followed by interval cytoreductive surgery (ICS) and postoperative chemotherapy for stage III/IV mullerian carcinomas such as ovarian, tubal and peritoneal carcinomas.
- Conditions
- Ovarian Neoplasms, Fallopian Tube Neoplasms, Peritoneal Neoplasms
- Trial name
- NCT00112086
- Testing
- Neoadjuvant chemotherapy (Paclitaxel and Carboplatin)
- Where
- Japan
- Volunteers
- 56 people
- Sponsor
- Japan Clinical Oncology Group
Intensive Care Unit Patients, Pain Management
Effects of Voice Records on Patient Outcomes Surgical Intensive Care Unit
This randomized kontrolled study is aimed to contribute to the literature on recognising, evaluating and reducing stress in the intensive care unit, which is one of the main responsibilities of surgical nurses, and to increase…
- Conditions
- Intensive Care Unit Patients, Pain Management, Stress Response
- Trial name
- NCT07007754
- Testing
- Voice recording playback
- Where
- Turkey (Türkiye)
- Volunteers
- 69 people
- Sponsor
- Aydin Adnan Menderes University
Umbilical Hernia
Umbilical Hernial Repair Using IPOM
local repair of umbilical hernia in cirrhotic patient using intraperitoneal onlay mesh technique
- Trial name
- NCT04088253
- Testing
- umbilical herneal repair
- Where
- Egypt
- Volunteers
- 20 people
- Sponsor
- Assiut University
Psychotic Disorders
Serial Comparisons of Abdominal and Neurological MRI Scans
The purpose of this study is to compare abdominal weight gain and fat distribution to changes in brain morphology in people taking antipsychotic medications.
- Trial name
- SCANMRI (NCT02009969)
- Where
- Canada
- Volunteers
- 40 people
- Sponsor
- University of British Columbia
Functional Abdominal Pain Syndrome
ICBT for Children With FAPDs - the Child's Pain Regulation
Functional abdominal pain disorders (FAPDs) in children are common (14%) and abdominal pain has increased rapidly in children during the last ten years in Sweden.
- Trial name
- NCT05945251
- Testing
- Internet-delivered cognitive behavioral therapy
- Where
- Sweden
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Karolinska Institutet
Incisional Hernia After Midline Laparotomy, Emergency Abdominal Surgery
Prophylactic Mesh Reinforcement Versus Primary Closure After Emergency Midline Laparotomy (PREEMPT)
The PREEMPT trial is a multicenter randomized controlled trial comparing prophylactic onlay biosynthetic mesh reinforcement with primary suture closure in adult patients undergoing emergency midline laparotomy.
- Trial name
- PREEMPT (NCT07753551)
- Testing
- Prophylactic Biosynthetic Mesh Placement, Direct suture
- Where
- Italy
- Volunteers
- 189 people
- Sponsor
- University of Rome Tor Vergata
One Hundred Patients Aged 65 and Older Who Underwent Emergency General Surgical Interventions, Clinical Utility of These Scoring Systems
A Comparative Study of CCI, EmSFI, and FTRST Scoring Systems
Frailty assessment tools and comorbidity indices play a crucial role, particularly in predicting outcomes for elderly patients undergoing emergency surgery.
- Conditions
- One Hundred Patients Aged 65 and Older Who Underwent Emergency General Surgical Interventions, Clinical Utility of These Scoring Systems, Gastrointestinal Neoplasms, Appendicitis Acute
- Trial name
- NCT06943924
- Testing
- Frailty assessment
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Dr. Lutfi Kirdar Kartal Training and Research Hospital
Complication, Anastomotic Leak
Prediction of Abdominal Complications After GastroEnterological Surgery
The aim of this multi-centered study is to understand the epidemiology of infectious complications after gastrointestinal surgery in China.
- Conditions
- Complication, Anastomotic Leak, Gastrointestinal Cancer
- Trial name
- PACAGE (NCT03828266)
- Testing
- No intervention
- Where
- 19 sites in China
- Volunteers
- 4,000 people
- Sponsor
- Peking University
Umbilical Hernia
Minimally Invasive Closure of Umbilical Hernias
The purpose of the study is to test the use of "Deflux" injections in a minimally invasive closure of umbilical (belly button) hernias in infants between birth and five years.
- Trial name
- MIC (NCT00706329)
- Testing
- Deflux
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- South Shore Hospital
Peritonitis
Single Versus Combined Antibiotic Therapy for Bacterial Peritonitis in CAPD Patients
To compare the efficacy of single versus combined antibiotic therapy for bacterial peritonitis in CAPD patients.
- Trial name
- NCT01785641
- Testing
- ceftazidime+ciprofloxacin, ceftazidime monotherapy, cefazolin+gentamicin
- Where
- Thailand
- Volunteers
- 300 people
- Sponsor
- Chulalongkorn University
Clinical Stage IV Gastric Cancer AJCC v8, Clinical Stage IVA Gastric Cancer AJCC v8
PIPAC for the Treatment of Peritoneal Carcinomatosis in Patients With Ovarian, Uterine, Appendiceal, Colorectal, or Gastric Cancer
This phase I trial studies the side effects of pressurized intraperitoneal aerosol chemotherapy (PIPAC) in treating patients with ovarian, uterine, appendiceal, stomach (gastric), or colorectal cancer that has spread to the…
- Conditions
- Clinical Stage IV Gastric Cancer AJCC v8, Clinical Stage IVA Gastric Cancer AJCC v8, Clinical Stage IVB Gastric Cancer AJCC v8, Malignant Uterine Neoplasm
- Trial name
- NCT04329494
- Testing
- Biopsy, Cisplatin, Doxorubicin
- Where
- 3 sites in United States
- Volunteers
- 49 people
- Sponsor
- City of Hope Medical Center
Aortic Aneurysms
Medical & Economical Evaluation of Fenestrated & Branched Stent-grafts to Treat Complex Aortic Aneurysms
The aim of this study is to prospectively compare the perioperative mortality severe morbidity and the costs of endovascular versus conventional surgical repair of pararenal, supra-renal and type 4 THORACO-abdominal aortic…
- Trial name
- Windows1 (NCT01168037)
- Testing
- Endovascular aortic repair with branched/fenestrated stent-graft, Open Surgical Repair
- Where
- France
- Volunteers
- 270 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Aortic Aneurysm, Abdominal
GORE EXCLUDER® Endoprosthesis - Low Permeability in Treatment of Abdominal Aortic Aneurysms
The purpose of this study is to evaluate the performance of the GORE EXCLUDER® Bifurcated Endoprosthesis-Low Permeability in the primary treatment of infrarenal abdominal aortic aneurysms.
- Trial name
- NCT00593814
- Testing
- GORE EXCLUDER® Bifurcated Endoprosthesis-Low Permeability
- Volunteers
- 139 people
- Sponsor
- W.L.Gore & Associates
Critical Illness, Intra-Abdominal Hypertension
Intraabdominal Pressure in Critically Ill Patients
This study is conducted to evaluate the incidence and prognostic significance of IAH in medical ICU patients.
- Trial name
- NCT03670771
- Testing
- Harrahill method for measuring of intraabdominal pressure
- Volunteers
- 100 people
- Sponsor
- Assiut University
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