Clinical trials: Abdomen Hernia
Open Abdomen, Incisional Hernia
Synthetic Mesh for Prevention of HernIa After opEn Abdomen cLosure stuDy
The aim of this clinical trial is to evaluate whether placement of a synthetic prophylactic onlay mesh during definitive fascial closure can reduce the incidence of incisional hernia in adult patients managed with an open abdomen…
- Conditions
- Open Abdomen, Incisional Hernia, Definitive Fascial Closure, Emergency Abdominal Surgery
- Trial name
- SHIELD (NCT07835334)
- Testing
- Definitive Fascial Closure Without Prophylactic Mesh, Prophylactic Onlay Mesh Placement
- Volunteers
- 30 people
- Sponsor
- Hospital San Juan de Dios Tenerife
Abdominal Wound Dehiscence, Burst Abdomen
Vacuum-Assisted Closure Versus Graduated Primary Skin Closure for Postoperative Burst Abdomen
Burst abdomen, or complete abdominal wound dehiscence, is a severe postoperative complication characterized by the separation of the musculo-aponeurotic layer of the abdominal wall.
- Conditions
- Abdominal Wound Dehiscence, Burst Abdomen, Surgical Wound Dehiscence
- Trial name
- NCT07797868
- Testing
- Vacuum-Assisted Closure (VAC) Therapy, Graduated Primary Skin Closure
- Volunteers
- 50 people
- Sponsor
- Assiut University
Incisional Hernia of Midline of Abdomen
Laparoscopic IPOM Plus vs. eTEP Trial
The survey will compare primary and secondary outcomes of laparoscopic intraperitoneal onlay mesh (IPOM plus) and extended totally extraperitoneal (eTEP) repair for incisional hernia.
- Trial name
- NCT05528107
- Testing
- Lap IPOM plus, eTEP
- Where
- Russia
- Volunteers
- 72 people
- Sponsor
- City Clinical Hospital No.1 named after N.I. Pirogov
Incisional Hernia, Incisional Hernia of Midline of Abdomen
Mesh Augmented Reinforcement of Abdominal Wall Suture Line to Limit the Rate of Incisional Hernia Occurrence
The purpose of this prospective, pivotal, multi-center, single-arm, pre-market, investigational clinical study is to assess the safety and performance of Deternia™ Self-Gripping Resorbable Mesh when used for suture line…
- Conditions
- Incisional Hernia, Incisional Hernia of Midline of Abdomen, Midline Laparotomy
- Trial name
- MARS (NCT05424484)
- Testing
- Self-Gripping Resorbable Mesh
- Where
- 13 sites in Croatia, Germany and 3 more
- Volunteers
- 123 people
- Sponsor
- Medtronic - MITG
Incisional Hernia of Midline of Abdomen, Surgical Wound
Onlay Mesh in Abdominal Aortic Aneurysm Repair.
The aim of the study was to compare the incidence of IH after abdominal aortic aneurysm (AAA) open repair according to the abdominal wall closure technique used.
- Trial name
- NCT07416422
- Testing
- Abdominal Ultrasound or computed tomography
- Where
- Spain
- Volunteers
- 50 people
- Sponsor
- Hospital Universitario Ramon y Cajal
Incisional Hernia of Midline of Abdomen
RCT Ventralex vs Onlay Mesh in Incisional Hernias
A radomised controlled trial comparing Ventralex patch and Progrip mesh in surgery for midline incisional hernias
- Trial name
- VPatchIncRCT (NCT04358159)
- Testing
- Ventralex, Progrip
- Where
- 2 sites in Sweden
- Volunteers
- 200 people
- Sponsor
- Karolinska Institutet
Abdomen Hernia, Respiratory Complication
Virtual Reality on Pulmonary Function After Upper Abdominal Surgeries
After upper abdomen surgery, respiratory muscle dysfunction is well recognised. After laparotomy and even laparoscopy, maximum static inspiratory and expiratory pressures are lowered, and recovery can take several days.
- Trial name
- NCT06301126
- Testing
- Virtual reality, conventional physical therapy exercise program
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Cairo University
Abdomen Hernia
The Effects of Post-Operative Interventions on Surgical Site Occurrences in AWR
Randomized controlled trial to compare SSO's in abdominal wall reconstruction patients using Prevena, Prineo, and traditional incisional dressings.
- Trial name
- NCT04906408
- Testing
- Prevena, Prineo, Traditional
- Where
- United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Ohio State University
Incisional Hernia After Midline Laparotomy, Quality of Life (QOL)
NoPro - Norwegian Hernia Prophylaxis Study
A multicenter randomized controlled trial comparing midline laparotomy closures using the small-bite suture technique alone to those using the small-bite suture technique with an additional onlay prophylactic polypropylene mesh.
- Conditions
- Incisional Hernia After Midline Laparotomy, Quality of Life (QOL), Burst Abdomen, Surgical Site Infections
- Trial name
- NoPro (NCT06858020)
- Testing
- Prophylactic polypropylene onlay mesh
- Where
- Norway
- Volunteers
- 150 people
- Sponsor
- Sykehuset Innlandet HF
Incisional Hernia of Midline of Abdomen
Open Vs. Endoscopic Transversus Abdominis Release Trial
This study aims to comparatively evaluate the early and long-term results of open and endoscopic TAR procedure for large midline incisional ventral hernias.
- Trial name
- NCT06195332
- Testing
- open TAR, endoscopic TAR
- Where
- Russia
- Volunteers
- 36 people
- Sponsor
- City Clinical Hospital No.1 named after N.I. Pirogov
Incisional Hernia of Midline of Abdomen
Barbed Suture for Emergency Midline Laparotomy Closure
Urgency surgeries are often performed in a stressful setting with critical patient involved. In this context, laparotomy closure can sometimes be the most neglected part of the procedure.
- Trial name
- BAROTOMY (NCT05351970)
- Testing
- Barbed
- Where
- Spain
- Volunteers
- 128 people
- Sponsor
- Fundación para el Fomento de la Investigación Sanitaria y Biomédica de la Comunitat Valenciana
Incisional Hernia of Midline of Abdomen
Midline Restoration After HYbriD Hernia RepAir Surgery (HYDRA)
The goal of this observational study is to learn about the functioning of the abdominal wall in patients who underwent hybrid (open- and laparoscopic) incisional hernia repair.
- Trial name
- HYDRA (NCT06286124)
- Testing
- Hybrid Surgery
- Where
- Netherlands
- Volunteers
- 52 people
- Sponsor
- Erasmus Medical Center
Open Abdomen, Temporary Abdominal Closure
Vacuum Assisted Wound Closure and Permanent On-lay Mesh-mediated Fascial Traction in Patients With Open Abdomen
Open abdomen therapy is used in trauma and non-trauma patients where the abdomen is not possible to close, or the intraabdominal conditions is not suitable for closure.
- Conditions
- Open Abdomen, Temporary Abdominal Closure, Incisional Hernia
- Trial name
- VAWCPOM (NCT05568238)
- Testing
- Vacuum Assisted Wound Closure and Permanent On-lay Mesh-mediated fascial traction (VAWCPOM)
- Volunteers
- 100 people
- Sponsor
- Skane University Hospital
Incisional Hernia of Midline of Abdomen
Algorithm for Prophylactic Mesh Use in Emergency Laparotomy.
Use of informed algorithm for patients selection of prophylactic mesh aplication after midline laparotomy in emergency surgery.
- Trial name
- NCT04808063
- Testing
- Prophylactic mesh implantation
- Where
- Spain
- Volunteers
- 100 people
- Sponsor
- Hospital del Mar
Incisional Hernia of Midline of Upper Abdomen, Incisional Hernia of Midline of Lower Abdomen
Double Mesh Modification of Incisional Hernia Can be Effective Without Severe Local Complications
22 patients of incisional hernia underwent treatment by double mesh modification of the original Chevrel's technique the primary outcome was recurrence, skin necrosis secondery out come was pain hematoma seroma
- Conditions
- Incisional Hernia of Midline of Upper Abdomen, Incisional Hernia of Midline of Lower Abdomen, Incisional Hernia of Midline of Abdomen
- Trial name
- NCT04166201
- Testing
- double mesh hernioplasty with modified chevrel's technique
- Where
- Egypt
- Volunteers
- 22 people
- Sponsor
- Zagazig University
Open Abdomen, Fascial Closure
Vacuum Assisted Wound Closure (VAWC) and Mesh Mediated Fascial Traction
The purpose of this multicenter trial is to prospectively evaluate a novel combination of vacuum assisted wound closure (VAWC) and mesh mediated fascial traction for closure of open abdomens.
- Trial name
- NCT00494793
- Testing
- VAWC and mesh mediated fascial traction
- Where
- 5 sites in Sweden
- Volunteers
- 111 people
- Sponsor
- Skane University Hospital
Hernia, Wound Infection
Suture Techniques to Reduce the Incidence of The inCisional Hernia
The objective of the study is reduction of the incidence of the most frequent complication of abdominal surgery, incisional hernia.
- Conditions
- Hernia, Wound Infection, Burst Abdomen, Pain
- Trial name
- STITCH (NCT01132209)
- Testing
- Closure of the abdominal wall after midline incisions
- Where
- Netherlands
- Volunteers
- 576 people
- Sponsor
- Erasmus Medical Center