Clinical trials: Abdominal
Metabolic Syndrome, Dyslipidemia
Impact of Consumption of Beta-glucans on the Intestinal Microbiota and Glucose and Lipid Metabolism
The purpose of this study is to investigate if daily consumption of barley beta-glucans effect lipid and glucose metabolism and alter intestinal microbiota composition in participants with metabolic syndrome or with high risk for…
- Conditions
- Metabolic Syndrome, Dyslipidemia, Obesity, Abdominal, Hyperglycemia
- Trial name
- NCT02041104
- Testing
- Bread with added beta-glucans
- Where
- 3 sites in Slovenia
- Volunteers
- 51 people
- Sponsor
- Mlinotest Zivilska Industrija d.d.
Metabolic Syndrome
Canadian Health Advanced By Nutrition and Graded Exercise
The overall objective of the CHANGE initiative is to change the delivery of care in primary care clinics to treat disease by reducing reliance on drugs and hospitals through the promotion of scientifically validated nutritional…
- Trial name
- CHANGE (NCT01616563)
- Testing
- Dietary Intervention, Exercise Prescription and Fitness Program
- Where
- 3 sites in Canada
- Volunteers
- 305 people
- Sponsor
- Daren K. Heyland
Age Problem, Abdominal Cancer
Dosage of Epidural Morphine in Elderly Patients
This a clinical trial that evaluates the efficacy and safety of three different doses of morphine, namely 1.5 mg, 3 mg and 4.5 mg, via the epidural route regarding reducing pain in elderly patients after a cancer surgery in the…
- Trial name
- NCT04316871
- Testing
- 1.5 mg of Morphine Sulfate, Normal saline, 3 mg of Morphine Sulfate
- Where
- Egypt
- Volunteers
- 96 people
- Sponsor
- Assiut University
Ventral Hernia
Study Of Hernia Repair Utilizing The Bard Ventrio Hernia Patch
This study will collect data on patients undergoing hernia repair using the Bard Ventrio Hernia Patch. The study will evaluate hernia recurrence rates, operating time, quality of life and complications associated with the device…
- Trial name
- NCT00866814
- Testing
- Bard Ventrio Hernia Patch
- Where
- 7 sites in United States
- Volunteers
- 119 people
- Sponsor
- C. R. Bard
Performance and Tolerance of Colonoscopy
Effectiveness of Abdominal Binder Use During Colonoscopy
Colonoscopy is considered the primary screening test for colorectal cancer screening worldwide. For technical difficulties previously experienced during colonoscopy, especially loop of the colonoscopy device in the colon, many…
- Trial name
- NCT04383132
- Testing
- Abdominal Binder
- Where
- Turkey (Türkiye)
- Volunteers
- 346 people
- Sponsor
- Sehit Prof. Dr. Ilhan Varank Sancaktepe Training and Research Hospital
Abdominal (ABD) Infection
INSPIRE Trial for Abdominal Infections
The INSPIRE Abdominal Infection Trial is a cluster-randomized controlled trial of HCA Healthcare hospitals comparing routine empiric antibiotic stewardship practices with real-time, precision medicine computerized physician order…
- Trial name
- NCT05423743
- Testing
- Arm 1: Routine Care, Arm 2: INSPIRE Stewardship Bundle for Abdominal Infection
- Where
- 101 sites in United States
- Volunteers
- 198,480 people
- Sponsor
- Harvard Pilgrim Health Care
Pancreatic Cancer, Pancreas Cancer
Daily Online Adaptation Versus Localization for MRI-Guided SBRT for Unresectable Primary or Oligometastatic Abdominal Malignancies
In light of this new technology and preliminary findings of low toxicity of online, adaptive, magnetic resonance (M)-guided stereotactic radiation on a single arm prospective study, the investigators propose to compare this…
- Conditions
- Pancreatic Cancer, Pancreas Cancer, Cancer of the Pancreas, Hepatocellular Carcinoma
- Trial name
- NCT02950025
- Testing
- Online, adaptive MR-guided SBRT, Online, non-adaptive MR-guided SBRT, European Organization for Research and Treatment of Cancer (EORTC) QLQ-30
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- Washington University School of Medicine
Pain, Constipation
Effect of Lidocaine and Esmolol to Improve the Quality of Recovery
The purpose of this prospective, randomized, double-blinded, active-controlled study is: To assess the effectiveness of systemic administration of lidocaine and esmolol in combination (vs.
- Conditions
- Pain, Constipation, Nausea, Vomiting
- Trial name
- NCT01114997
- Testing
- Lidocaine, Esmolol, Lidocaine + Esmolol (Combo)
- Where
- United States
- Volunteers
- 32 people
- Sponsor
- Cedars-Sinai Medical Center
Laparoscopic Surgery
Device to Assist With Abdominal Access During Laparoscopic Surgery
The purpose of this study is to assess the safety and ease of use of a TauTona Pneumoperitoneum Assist Device (TPAD) to assist with obtaining peritoneal access with a Veress needle, and for placing a primary trocar, during…
- Trial name
- NCT04392635
- Testing
- TauTona Pneumoperitoneum Assist Device (TPAD), Standard of Care (SOC)
- Where
- United States
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- Stanford University
Ovarian Neoplasm, Fallopian Tube Neoplasms
Relacorilant in Combination With Nab-Paclitaxel in Advanced, Platinum-Resistant, High-Grade Epithelial Ovarian, Primary Peritoneal, or Fallopian-Tube Cancer
The primary objectives of this study are to evaluate progression-free survival (PFS) by blinded independent central review (BICR) and overall survival (OS) (evaluated independently, as dual primary endpoints) in patients treated…
- Conditions
- Ovarian Neoplasm, Fallopian Tube Neoplasms, Peritoneal Neoplasms
- Trial name
- NCT05257408
- Testing
- Relacorilant 150 mg, Nab-paclitaxel 80 mg/m^2, Nab-paclitaxel 100 mg/m^2
- Where
- 116 sites in United States, Argentina and 12 more
- Volunteers
- 381 people
- Sponsor
- Corcept Therapeutics
Intra-abdominal Infection, Complicated Intra-abdominal Infection
Study of Ceftolozane/Tazobactam (MK-7625A) in Combination With Metronidazole in Japanese Participants With Complicated Intra-abdominal Infection (MK-7625A-013)
This is a Phase 3, multi-site, non-randomized, open-label study evaluating the safety and efficacy of MK-7625A 1.5 g (ceftolozane 1 g/tazobactam 0.5 g) plus metronidazole 500 mg for the treatment of Complicated Intra-abdominal…
- Trial name
- NCT02739997
- Testing
- MK-7625A 1.5 g (ceftolozane 1 g/tazobactam 0.5 g), metronidazole 500 mg
- Volunteers
- 100 people
- Sponsor
- Merck Sharp & Dohme LLC
Subjects Referred to CT-examination of the Abdomen
A Randomized, Controlled Trial to Evaluate CT Image Quality Lumentin® 44
Subjects referred for abdominal or thoracoabdominal CT-examination will be randomised to either the three contrast agents Lumentin® 44, Omnipaque® or Movprep.
- Trial name
- NCT03326518
- Testing
- Lumentin® 44, Diluted Omnipaque®, Movprep®
- Where
- Sweden
- Volunteers
- 45 people
- Sponsor
- Lument AB
Abdominal Aortic Aneurysms (AAA)
The Pivotal Study of the Aptus Endovascular AAA Repair System
A prospective, non-randomized, multi-center clinical study to evaluate the safety and effectiveness of the Aptus Endovascular AAA Repair System compared to an open surgical repair historical control group in the treatment of…
- Trial name
- STAPLE-2 (NCT00507559)
- Testing
- Aptus Endovascular AAA Repair System
- Where
- 2 sites in United States
- Volunteers
- 155 people
- Sponsor
- Medtronic Cardiovascular
Abdominal Hysterectomy (& Wertheim)
Lidocaine and Ketamine in Abdominal Surgery
This study is being done to determine if combined infusions of lidocaine and ketamine is better than a lidocaine or ketamine infusion alone, or to placebo in improving recovery after abdominal hysterectomy.
- Trial name
- NCT00721110
- Testing
- Lidocaine, Ketamine, Ketamine + Lidocaine
- Where
- United States
- Volunteers
- 64 people
- Sponsor
- The Cleveland Clinic
Abdominal Aortic Aneurysm, AAA
Endurant Evo International Clinical Trial
The purpose of this trial is to evaluate the safety and effectiveness of the Endurant Evo Abdominal Aortic Aneurysm (AAA) Stent graft system for endovascular treatment of subjects with infrarenal abdominal aortic or aortoiliac…
- Trial name
- NCT02461524
- Testing
- Endurant Evo AAA Stent Graft System, Endovascular aneurysm repair (EVAR)
- Where
- 9 sites in Austria, Belgium and 3 more
- Volunteers
- 69 people
- Sponsor
- Medtronic Cardiovascular
Pre Diabetes, Polycystic Ovary Syndrome
Liraglutide 3mg (Saxenda) on Weight, Body Composition, Hormonal and Metabolic Parameters in Obese Women With PCOS
There is a growing need to develop pharmacologic interventions to improve metabolic function in women with polycystic ovary syndrome (PCOS).
- Conditions
- Pre Diabetes, Polycystic Ovary Syndrome, Obesity Android
- Trial name
- SAXAPCOS (NCT03480022)
- Testing
- Liraglutide Pen Injector [Saxenda]
- Where
- United States
- Volunteers
- 88 people
- Sponsor
- Woman's
Pain, Postoperative, Anesthesia
Transversus Abdominal Plane Block at Total Laparoscopic Hysterectomy: Effect on Quality of Recovery
The Transversus Abdominal Plane (TAP) block has been used with good success to decrease postoperative pain following laparatomy.
- Trial name
- TAP (NCT01479270)
- Testing
- TAP Block
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- MetroHealth Medical Center
Hemostasis
HEMOBLAST Pivotal Clinical Investigation
The purpose of this prospective, randomized, controlled study is to evaluate the safety and efficacy of a new hemostatic device (HEMOBLAST™ Bellows) compared to a control device, absorbable gelatin sponge USP with thrombin.
- Trial name
- NCT02780869
- Testing
- HEMOBLAST Bellows, Absorbable gelatin sponge, USP with thrombin
- Where
- 17 sites in United States
- Volunteers
- 258 people
- Sponsor
- Biom'Up France SAS
Abdominal Aortic Aneurysm
Preferences for Open Vs. Endovascular Repair for Abdominal Aortic Aneurysm
This study tests the use of a decision aid for Veterans who are facing a decision about surgery for their Abdominal Aortic Aneurysm (AAA).
- Trial name
- PROVE-AAA (NCT03115346)
- Testing
- Decision aid
- Where
- 22 sites in United States
- Volunteers
- 241 people
- Sponsor
- VA Office of Research and Development
Abdominal Aortic Aneurysm (AAA)
ACZ885 for the Treatment of Abdominal Aortic Aneurysm
This study was designed to assess the safety, tolerability and efficacy of ACZ885 on aneurysmal growth rate in subjects with abdominal aortic aneurysms (AAA).
- Trial name
- AAA (NCT02007252)
- Testing
- ACZ885
- Where
- 9 sites in United States, Denmark and 3 more
- Volunteers
- 65 people
- Sponsor
- Novartis Pharmaceuticals