Clinical trials: Abdominal (ABD) Infection
Surgical Site Infection, Complication,Postoperative
Study to Analyze the Surgical Site Infections in a Group of Patients Who Were Randomly Applied a Negative Pressure Therapy Dressing Versus Conventional Dressing
Surgical site complications generate a series of consequences that prolong hospital stay, increase interventions and procedures, and consequently considerably increase healthcare costs.
- Conditions
- Surgical Site Infection, Complication,Postoperative, Surgical Wound Infection, Surgical Complication
- Trial name
- NCT05455801
- Testing
- negative preassure wound therapy
- Where
- Spain
- Volunteers
- 271 people
- Sponsor
- Hospital Universitario Central de Asturias
Laryngeal Masks, Pharyngitis
Postoperative Sore Throat in Children: Comparison Between Two Supraglottic Devices, Ambu® AuraOnce™ Laryngeal Mask Airway (LMA) and I-Gel®.
Sore throat is minor but well recognized complaint after receiving general anaesthesia. It is rated as 8th most undesirable outcome in postoperative period.It not only affects the patient's satisfaction but also can affect…
- Conditions
- Laryngeal Masks, Pharyngitis, Minors, Anesthesia
- Trial name
- NCT03140228
- Testing
- I-Gel, LMA
- Where
- Pakistan
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Aga Khan University
Sepsis
Immune Activation, Hypoxia and Vasoreaction in Sepsis of Pulmonary Versus Abdominal Origin
Sepsis remains a common entity in critical care patients with remarkable mortality. Pulmonary and abdominal infections (with subsequent sepsis) are the most common in the ICU.
- Trial name
- NCT01530932
- Where
- Germany
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Universitätsmedizin Mannheim
Bacterial Translocation, Surgical Site Infection
Plastic Wound Retractors and Bacterial Translocation in Abdominal Surgery
Hypothesis: Plastic wound retractors reduce passage of bacteria from the abdomen to the surgical incision site in abdominal surgery Currently, plastic wound retractors are used in abdominal surgery to facilitate access to the…
- Conditions
- Bacterial Translocation, Surgical Site Infection, Abdominal Surgery, Wound Infection
- Trial name
- NCT01007487
- Where
- 2 sites in Ireland
- Volunteers
- 250 people
- Sponsor
- St Vincent's University Hospital, Ireland
Appendicitis, Abdominal Abscess
Irrigation Versus Suction in Complicated Acute Appendicitis
This study evaluates the intraabdominal abscess rate after laparoscopic appendectomy in complicated acute appendicitis performing irrigation of the abdominal cavity or only suction without lavage.
- Conditions
- Appendicitis, Abdominal Abscess, Acute Disease, Cecal Diseases
- Trial name
- ISAAC (NCT02688244)
- Testing
- Irrigation, No irrigation
- Where
- Spain
- Volunteers
- 210 people
- Sponsor
- Hospital Universitario Virgen de la Arrixaca
Hospital Acquired Pneumonia, Ventilator Acquired Pneumonia
Real-World Study of Ceftazidime Avibactam in China
This observational study will enroll approximately 450 in patients. Patients treated with CAZ AVI for at least 1 dose at around 20 research centers in China will be enroll.
- Conditions
- Hospital Acquired Pneumonia, Ventilator Acquired Pneumonia, Complicated Intra Abdominal Infections
- Trial name
- REACT (NCT05487586)
- Testing
- ceftazidime avibactam group
- Where
- 17 sites in China
- Volunteers
- 220 people
- Sponsor
- Pfizer
Abdominal Abscess
Abdominal aBscess Catheter Sclerotherapy (ABCS)
This is a single center, two arm phase I/II clinical trial exploring the use of chemical sclerosants (ethanol and povidone iodine) in decreasing the time needed for catheter drainage for patients with non-fistulous intraabdominal…
- Trial name
- ABCS (NCT06906029)
- Testing
- Catheter Sclerotherapy
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- University of Alabama at Birmingham
Surgical Site Infections
Study to Assess the Safety & Efficacy of Oral Ciprodiazole Versus Currently Used Ciprofloxacin & Metronidazole
This study aims to assess the safety \& efficacy of Oral Ciprodiazole® versus currently used Ciprofloxacin Tablets \& Metronidazole tablets in pelvi-abdominal infections and following IV antibiotics in post-operative period, for…
- Trial name
- CIPRO-001 (NCT05863832)
- Testing
- Ciprodiazole, Ciprofloxacin Tablets & Metronidazole tablets
- Where
- Egypt
- Volunteers
- 312 people
- Sponsor
- MinaPharm Pharmaceuticals
Infectious Complications, Postoperative Pain
Early Postoperative Pain and 30-day Complications Following Major Abdominal Surgery: an Observational Study
In this retrospective cohort study, we assess the relationship between the intensity of early postoperative pain and the risk of infectious- and non-infectious complications within 30 days after major abdominal surgery.
- Conditions
- Infectious Complications, Postoperative Pain, Acute Pain, Postoperative Complications
- Trial name
- NCT05244655
- Where
- Netherlands
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Radboud University Medical Center
Complicated Intra Abdominal Infections
Antibiotic Safety (SCAMP)
The main purpose of this study is evaluate whether it is safe or not to use various combination of antibiotics (ampicillin, metronidazole, clindamycin, piperacillin-tazobactam, gentamicin) in treating infants with complicated…
- Trial name
- SCAMP (NCT01994993)
- Testing
- ampicillin and metronidazole and gentamicin, ampicillin and gentamicin and clindamycin, gentamicin and Piperacillin- tazobactam
- Where
- 50 sites in United States, Canada
- Volunteers
- 260 people
- Sponsor
- Michael Cohen-Wolkowiez
Urinary Tract Infection (cUTI), Intra-abdominal Infection (cIAI) and
Reporting Patterns and Results of Initial Antibiotic Treatment in Patients With cUTI, cIAI,NP Including VAP
Reporting patterns and results of initial antibiotic treatment in patients with complicated urinary tract infection (cUTI), complicated intra-abdominal infection (cIAI) and nosocomial pneumonia (NP) including…
- Conditions
- Urinary Tract Infection (cUTI), Intra-abdominal Infection (cIAI) and, Nosocomial Pneumonia (NP)
- Trial name
- RECOMMEND (NCT02364284)
- Where
- 27 sites in Brazil, France and 4 more
- Volunteers
- 1,322 people
- Sponsor
- Pfizer
Bowel Surgery
Restricted Fluid Regimen in Open Abdominal Bowel Surgery
Liberal intravenous fluid resuscitation during open abdominal surgery may predispose the patients to multiorgan dysfunction, prolong hospital stay and increase postoperative morbidity.
- Trial name
- NCT00456703
- Testing
- intraoperative fluid management, fluid restriction
- Where
- United States
- Sponsor
- Beth Israel Deaconess Medical Center
Intra-Abdominal Infection, Candida
Rezafungin Peritoneal Diffusion for Intra-abdominal Candidiasis
ntra-abdominal candidiasis is a serious infection common in critically ill patients, often leading to high mortality if not treated quickly.
- Conditions
- Intra-Abdominal Infection, Candida, Abdominal Surgery Patients, Critically Ill Intensive Care Unit Patients
- Trial name
- REAREZ (NCT07093203)
- Where
- France
- Volunteers
- 18 people
- Sponsor
- Central Hospital, Nancy, France
Intraabdominal Abscess After Procedure, Leakage
Outcome After Laparoscopic Surgery for Peptic Ulcer Perforation
Despite advances in laparoscopic surgery for perforated peptic ulcer (PPU), intra-abdominal abscess (IAA) is recognized as one of the commonly reported complications with relation to the extent of infectious abdominal…
- Conditions
- Intraabdominal Abscess After Procedure, Leakage, Pneumonia, Operation Wound; Infection
- Trial name
- NCT05147870
- Testing
- Peritoneal irrigation, Suction only
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Chang Wei-Jung
Other Acute Illnesses Presenting to the Hospital, Heart Failure
Evaluation of Implementation of a National Point-of-Care Ultrasound Training Program
This VA QUERI Partnered Evaluation Initiative will evaluate the impact of an immersive Point-of-care Ultrasound (POCUS) Training Course on provider skill acquisition and retention; the frequency of POCUS use by trained providers…
- Conditions
- Other Acute Illnesses Presenting to the Hospital, Heart Failure, Pneumonia, Deep Venous Thrombosis
- Trial name
- NCT03296280
- Where
- United States
- Volunteers
- 116 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Abdominal Compartment Syndrome, Pancreatitis,Acute Necrotizing
Fasciotens to Treat an Open Abdomen - a Prospective Cohort Study
The open abdomen can occur as a result of various diseases. After infections of the abdomen, compartment syndromes or traumata, it is essential for survival (1). This condition of the open abdomen lasts from days to months.
- Conditions
- Abdominal Compartment Syndrome, Pancreatitis,Acute Necrotizing, Intraabdominal Hypertension, Peritonitis
- Trial name
- Fasciotens (NCT04033614)
- Testing
- Fasciotens-Abdomen
- Where
- Germany
- Volunteers
- 15 people
- Sponsor
- RWTH Aachen University
Complicated Urinary Tract Infection, Acute Pyelonephritis
P3 Study to Assess Efficacy and Safety of Cefepime/Nacubactam and Aztreonam/Nacubactam Versus Best Available Therapy for Adults With Infection Due to Carbapenem Resistant Enterobacterales
This study is a multi-center, randomized, single-blind, parallel-group study to assess the efficacy and safety, when nacubactam is coadministered with cefepime or aztreonam, compared with best available therapy (BAT), in the…
- Conditions
- Complicated Urinary Tract Infection, Acute Pyelonephritis, Hospital-acquired Bacterial Pneumonia, Ventilator-associated Bacterial Pneumonia
- Trial name
- Integral-2 (NCT05905055)
- Testing
- co-administration of cefepime and nacubactam, co-administration of aztreonam and nacubactam, BAT
- Where
- 54 sites in China, Croatia and 12 more
- Volunteers
- 126 people
- Sponsor
- Meiji Seika Pharma Co., Ltd.
Cryptogenic Pyogenic Liver Abscess
Prevalence of Colon Cancer in Pyogenic Liver Abscess
Although a proportion of pyogenic liver abscess may originated from colonic mucosal lesions, the prevalence of colonic neoplasm in the patients with pyogenic liver abscess are still not evaluated yet.
- Trial name
- NCT02032914
- Where
- 2 sites in South Korea
- Volunteers
- 62 people
- Sponsor
- Inje University
Intra-Abdominal Infections, Skin Disease, Infectious
Post-Authorization Study Evaluating Safety Of Tigecycline
This is a study to evaluate the safety of tigecycline in patients with complicated intra-abdominal infections (cIAI) and complicated skin and soft tissue infections (cSSTI) under real practice in the usual hospital setting and…
- Conditions
- Intra-Abdominal Infections, Skin Disease, Infectious, Soft Tissues Infections
- Trial name
- HORUS (NCT00827541)
- Testing
- Tigecycline
- Volunteers
- 115 people
- Sponsor
- Pfizer
COVID-19, Emergency Surgery
Treatment and Outcomes in Patients With COVID-19 and Competing Acute Surgical Diseases in Moscow
The COVID-19 pandemic has posed a significant challenge to surgical practice. This study aims to investigate the structure of hospitalizations, treatment outcomes, and surgical tactics in patients with COVID-19 and competing…
- Conditions
- COVID-19, Emergency Surgery, Abdominal Surgery, Real-World Data
- Trial name
- SurgCOVID-Mos (NCT07719166)
- Testing
- Surgical and Interventional Management of Acute Surgical Conditions
- Where
- Russia
- Volunteers
- 58,000 people
- Sponsor
- Pirogov Russian National Research Medical University