Clinical trials: Abdominal (ABD) Infection
Abdominal Aortic Aneurysm
Abdominal Aortic Aneurysm Surgery and Thrombosis
The aim of our study is to evaluate the incidence of post-operative thrombotic complications after abdominal aortic aneurysm surgery in the context of atherosclerosis or infectious aneurysm and its links with preoperative…
- Trial name
- AAA-IT (NCT04325373)
- Where
- France
- Volunteers
- 40 people
- Sponsor
- University Hospital, Bordeaux
Liver Abscess
Ciprofloxacin Plus Metronidazole Vs Cefixime Plus Metronidazole Therapy for the Treatment of Liver Abscess
Liver abscess is purulent collections in the liver parenchyma that result from microbial infection spread to the liver through the biliary tree, hepatic or portal vein and by extension of adjacent infection or as a result of…
- Trial name
- CMETRO (NCT03969758)
- Testing
- Ciprofloxacin, Cefixime
- Where
- India
- Volunteers
- 140 people
- Sponsor
- Post Graduate Institute of Medical Education and Research, Chandigarh
Laparotomy Closure After Abdominal Surgery, Suture Materials
Comparison of Vicryl Versus Prolene for Midline Rectus Sheath Closure After Elective Laparotomy
This randomized controlled trial compared two commonly used suture materials, Prolene and Vicryl, for closing the midline rectus sheath after elective laparotomy.
- Conditions
- Laparotomy Closure After Abdominal Surgery, Suture Materials, Complications Wounds
- Trial name
- NCT07451990
- Testing
- Vicryl (Polyglactin 910) Suture, Prolene (Polypropylene) Suture
- Where
- Pakistan
- Volunteers
- 152 people
- Sponsor
- Hayatabad Medical Complex
Laparoscopic Surgery, Acute Appendicitis With Rupture
Open to Laparoscopic Reverse Conversion of Perforated Appendicitis
A Prospective Randomized Controlled Trial of Reverse Conversion (Open to Laparoscopic) in management of Acute Perforated Appendicitis
- Conditions
- Laparoscopic Surgery, Acute Appendicitis With Rupture, Sepsis, Abdominal Abscess
- Trial name
- reverse (NCT05283733)
- Testing
- reverse conversion technique
- Where
- Egypt
- Volunteers
- 426 people
- Sponsor
- Zagazig University
Ventral Hernia, Umbilical Hernia
Case-control Study of Mesh-infection After a Size Tailored Hernia Repair With C-Qur V-Patch
Ventral hernias, such as umbilical, epigastric and trocar-site hernias, are best repaired with abdominal wall reinforcement by mesh implantation.
- Conditions
- Ventral Hernia, Umbilical Hernia, Epigastric Hernia, Trocar-site Hernia
- Trial name
- Re-SITUP (NCT01761708)
- Testing
- primary ventral hernia repair with mesh
- Where
- Belgium
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- Algemeen Ziekenhuis Maria Middelares
Sepsis, Cardiac Arrest
Validation of Molecular and Protein Biomarkers in Sepsis
Background: Sepsis (blood poisoning) is a clinical syndrome characterised by a dysregulated host response to infection causing life-threatening organ dysfunction which results in admission to an intensive care unit.
- Conditions
- Sepsis, Cardiac Arrest, Pneumonia, Abdominal Sepsis
- Trial name
- VAMp-sepsis (NCT04289506)
- Testing
- mRNA expression
- Where
- 3 sites in United Kingdom
- Volunteers
- 270 people, healthy volunteers welcome
- Sponsor
- Public Health England
COVID-19, Emergency Surgery
Treatment and Outcomes in Patients With COVID-19 and Competing Acute Surgical Diseases in Moscow
The COVID-19 pandemic has posed a significant challenge to surgical practice. This study aims to investigate the structure of hospitalizations, treatment outcomes, and surgical tactics in patients with COVID-19 and competing…
- Conditions
- COVID-19, Emergency Surgery, Abdominal Surgery, Real-World Data
- Trial name
- SurgCOVID-Mos (NCT07719166)
- Testing
- Surgical and Interventional Management of Acute Surgical Conditions
- Where
- Russia
- Volunteers
- 58,000 people
- Sponsor
- Pirogov Russian National Research Medical University
Human Immunodeficiency Virus Type 1 (HIV-1)
Study to Assess the Effects of Cabotegravir (CAB) and Rilpivirine (RPV) Long-Acting (LA) Injections Following Sub-cutaneous (SC) Administration Compared With Intramuscular (IM) Administration in Adult Participants Living With Human Immunodeficiency Virus (HIV-1) Infection in the FLAIR Study
This study will assess the pharmacokinetics, safety, tolerability, maintenance of virological suppression and patient reported outcomes for participants receiving CAB and RPV LA injections following SC administration in the…
- Trial name
- NCT05896748
- Testing
- Cabotegravir - Injectable Suspension (CAB LA), Rilpivirine - Injectable Suspension (RPV LA)
- Where
- 30 sites in United States, Canada and 4 more
- Volunteers
- 94 people
- Sponsor
- ViiV Healthcare
Trauma Injury, Major Abdominal Surgery
Bolus Versus Continuous Enteral Tube Feeding
Stress metabolisms induced by severe trauma, large abdominal surgery procedures, sepsis, etc. leads to metabolic changes, which increase energy expenditure, enhanced protein catabolism, insulin resistance.
- Conditions
- Trauma Injury, Major Abdominal Surgery, Sepsis
- Trial name
- NCT04080479
- Testing
- Quadriceps Muscle Layer Fitness, Muscle Strength, Acute Physiology and Chronic Health Evaluation
- Where
- Czechia
- Volunteers
- 60 people
- Sponsor
- University Hospital Ostrava
Other Acute Illnesses Presenting to the Hospital, Heart Failure
Evaluation of Implementation of a National Point-of-Care Ultrasound Training Program
This VA QUERI Partnered Evaluation Initiative will evaluate the impact of an immersive Point-of-care Ultrasound (POCUS) Training Course on provider skill acquisition and retention; the frequency of POCUS use by trained providers…
- Conditions
- Other Acute Illnesses Presenting to the Hospital, Heart Failure, Pneumonia, Deep Venous Thrombosis
- Trial name
- NCT03296280
- Where
- United States
- Volunteers
- 116 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Abscess, Intra-Abdominal, Abdominal Abscess
A Safety and Tolerability Study of Doripenem Compared With Meropenem in Children Hospitalized With Complicated Intra-abdominal Infections
The purpose of the study is to evaluate the safety and tolerability of doripenem compared with meropenem in children hospitalized with complicated intra-abdominal infections.
- Conditions
- Abscess, Intra-Abdominal, Abdominal Abscess, Abdomen, Acute, Abdominal Pain
- Trial name
- NCT01110382
- Testing
- Doripenem, Meropenem, Amoxicillin/clavulanate potassium
- Where
- 19 sites in United States, Argentina and 6 more
- Volunteers
- 41 people
- Sponsor
- Janssen Research & Development, LLC
Ventral Hernia
Repair of Large Incisional Hernias - To Drain or Not to Drain Randomised Clinical Trial
The aim of this study was to perform a randomised clinical trial comparing the use of closed-suction tubular drains and progressive tension sutures in individuals with large incisional hernias subjected to onlay mesh repair to…
- Trial name
- NCT02163460
- Testing
- Drain, Progressive Tension Sutures
- Where
- Brazil
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Universidade Estadual do Oeste do Paraná
Dengue Fever
Abdominal Sonographic Findings and Their Association With Thrombocytopenia in Dengue Fever: A Cross-Sectional Study From an Endemic Region
Dengue fever is a common mosquito-borne viral infection in many tropical regions, including Sudan. Some patients develop severe forms of the disease, such as dengue hemorrhagic fever, which can lead to plasma leakage, bleeding…
- Trial name
- NCT07621848
- Where
- Sudan
- Volunteers
- 150 people
- Sponsor
- National Center for Gastroentestinal and Liver Disease
Intraabdominal Abscess After Procedure, Leakage
Outcome After Laparoscopic Surgery for Peptic Ulcer Perforation
Despite advances in laparoscopic surgery for perforated peptic ulcer (PPU), intra-abdominal abscess (IAA) is recognized as one of the commonly reported complications with relation to the extent of infectious abdominal…
- Conditions
- Intraabdominal Abscess After Procedure, Leakage, Pneumonia, Operation Wound; Infection
- Trial name
- NCT05147870
- Testing
- Peritoneal irrigation, Suction only
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Chang Wei-Jung
Pancreaticoduodenectomy, Distal Pancreatectomy
Randomized Trial of Early Versus Standard Drainage Removal After Pancreatic Resections
Despite a substantial decrease in postoperative mortality, morbidity after pancreatic resections is still high, even at high-volume centers.
- Conditions
- Pancreaticoduodenectomy, Distal Pancreatectomy, Pancreatic Fistula, Abdominal Abscess
- Trial name
- NCT00931554
- Testing
- Postoperative drain removal
- Where
- Italy
- Volunteers
- 114 people
- Sponsor
- Universita di Verona
Abdominal Abscess
Use of Iterative Reconstruction Method in Ultralow-dose CT for Follow-up of Patients With Intraabdominal Abscess: Comparison With Standard Dose CT
Increasing radiation exposure by medical examinations is getting more concerns. For optimal medical imaging, reducing radiation exposure with preservation image quality is important.
- Trial name
- NCT03681665
- Testing
- ultralow dose abdominopelvic CT
- Where
- South Korea
- Volunteers
- 20 people
- Sponsor
- Yonsei University
Suture Techniques, Wound Closure Techniques
Small Bites Vs Large Bites Abdominal Midline Incisional Closure
The goal of this trial is to compare the effectiveness of small bite versus large bite abdominal incision closure in emergency settings. It will also evaluate the safety and outcomes of each technique.
- Conditions
- Suture Techniques, Wound Closure Techniques, Laparotomy/Standerds, Surgical Wound Dehiscence
- Trial name
- NCT07154277
- Testing
- Small bite closure, Large bite closure
- Where
- Pakistan
- Volunteers
- 200 people
- Sponsor
- Dow University of Health Sciences
A Potential Infectious Respiratory Clinical Syndrome, Potential Clinical Urinary Infectious Syndrome
Value of Flow Cytometry in Infectious Point of Care: Feasibility Study
The purpose of this project is to validate the diagnostic orientation properties of two new biomarkers (CD64, CD169) for patients with infectious syndromes arriving in emergency departments.
- Conditions
- A Potential Infectious Respiratory Clinical Syndrome, Potential Clinical Urinary Infectious Syndrome, A Potential Clinical Abdominal Infection Syndrome
- Trial name
- NCT03912870
- Testing
- Value of Flow Cytometry in Infectious Point of Care
- Where
- France
- Volunteers
- 96 people
- Sponsor
- Assistance Publique Hopitaux De Marseille
Acute Appendicitis, Acute Appendicitis With Rupture
Prostaglandin-E Urinary Metabolite (PGE-M) as a Predictor of Acute Appendicitis in Children
Diagnosing acute appendicitis in children remains a clinical challenge, with delayed or incorrect diagnosis potentially leading to serious complications or unnecessary surgery.
- Conditions
- Acute Appendicitis, Acute Appendicitis With Rupture, Abdominal Pain (AP)
- Trial name
- NCT07008092
- Testing
- Blood specimen collection, Urine collection
- Where
- Croatia
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- KBC Split
Hernia, Ventral
Complex Ventral Hernia Repair Using Biologic or Synthetic Mesh
Hernias are often treated using a prosthetic mesh to add support to the healing wound. Prosthetic meshes have been used for decades to repair ventral hernias, level 1 data regarding which type of mesh to use is limited.
- Trial name
- CVHR (NCT02041494)
- Testing
- Ventralight, Strattice
- Where
- United States
- Volunteers
- 165 people
- Sponsor
- Hobart Harris