Clinical trials: Abdominal Aorta Aneurysm
Abdominal Aortic Aneurysms
Physician-Sponsored IDE for Talent Endoluminal Spring Graft System in Patients With Abdominal Aortic Aneurysms (AAA)
The purpose of this study is to evaluate the safety and effectiveness of the Talent Endoluminal Spring Graft System, an investigational device, to treat abdominal aortic aneurysms (AAA).
- Trial name
- NCT00695253
- Testing
- Talent Endoluminal Spring Graft System
- Where
- United States
- Volunteers
- 49 people
- Sponsor
- Rodney A. White, M.D.
Juxtarenal Aortic Aneurysm, Suprarenal Aortic Aneurysm
Evaluation of the Cook Custom Aortic Endograft, the Zenith t-Branch Endovascular Graft, and Surgeon-Modified Endograft in Treating Aortic Pathologies
This is a single-center study to evaluate the safety and effectiveness of three investigational devices, the Cook Custom Aortic Endograft, the Zenith t-Branch Endovascular Graft, and the Surgeon-Modified Endografts in the…
- Conditions
- Juxtarenal Aortic Aneurysm, Suprarenal Aortic Aneurysm, Thoracoabdominal Aortic Aneurysm, Penetrating Aortic Ulcer
- Trial name
- NCT02043691
- Testing
- Cook Custom Aortic Endograft, Zenith t-Branch Endovascular Graft, Surgeon-Modified Endograft
- Where
- United States
- Volunteers
- 410 people
- Sponsor
- University of Alabama at Birmingham
Abdominal Aortic Aneurysm
Study of the Endovascular QUANTUM LP™ Stent Graft System in Abdominal Aortic Aneurysms (AAA)
The objective of this clinical study is to assess the safety and effectiveness of the Cordis Endovascular Quantum LP™ Stent Graft System.
- Trial name
- NCT00233688
- Testing
- QUANTUM LP™ STENT GRAFT SYSTEM, Open surgical repair
- Where
- United States
- Volunteers
- 300 people
- Sponsor
- Cordis US Corp.
Abdominal Aortic Aneurysm
Korean Registry of Percutaneous EVAR With INCRAFT Stent Graft for the Treatment of Abdominalaortic Aneurysm (K-INCRAFT)
The sudy purpose is to investigate efficacy and safety of percutaneous endovascular aortic aneurysm repair using INCRAFT stent graft for Korean patients with abdominal aortic aneurysm.
- Trial name
- NCT03952780
- Where
- South Korea
- Volunteers
- 86 people
- Sponsor
- Yonsei University
Abdominal Aortic Aneurysm
Poland-Italy Aortic Research Bridge Real World Registry
Objective To pragmatically collect and analyze patient-level clinical, procedural, and outcome data from participating centers in Italy and Poland on the use of the PERCUTEK Tycheseal™ stent-graft system for the endovascular…
- Trial name
- POWER (NCT07476196)
- Where
- 26 sites in Italy, Poland
- Volunteers
- 200 people
- Sponsor
- American Heart of Poland
Abdominal Aortic Aneurysm Without Rupture
Secondary Intervention and Surveillance After EVAR
This is a retrospective cohort study of consecutive patients submitted to elective EVAR, between February/2009 and May/2019 in a single institution.
- Trial name
- NCT05335642
- Testing
- EVAR
- Where
- Portugal
- Volunteers
- 214 people
- Sponsor
- Hospital Sao Joao
Abdominal Aortic Aneurysm, Pararenal Aortic Aneurysm
GORE® EXCLUDER® Thoracoabdominal Branch Endoprosthesis Post-Approval Study
This study aims to confirm that the benefit-risk assessment of the GORE® EXCLUDER® Thoracoabdominal Branch Endoprosthesis (TAMBE Device) remains positive in real-world use and to ensure the adequacy of the TAMBE Device training…
- Conditions
- Abdominal Aortic Aneurysm, Pararenal Aortic Aneurysm, Thoracoabdominal Aortic Aneurysm
- Trial name
- NCT06578741
- Testing
- GORE® EXCLUDER® Thoracoabdominal Branch Endoprosthesis (TAMBE Device)
- Where
- United States
- Volunteers
- 310 people
- Sponsor
- W.L.Gore & Associates
Abdominal Aortic Aneurysms
Preoperative Methylprednisolone in Endovascular Aortic Repair
The purpose of this study is to attenuate the systemic inflammatory response after Endovascular repair of abdominal aortic aneurysms, by administration of a single preoperative dosage of Methylprednisolone.
- Trial name
- POMEVAR (NCT00989729)
- Testing
- Methylprednisolone, Physiological Saline
- Where
- Denmark
- Volunteers
- 150 people
- Sponsor
- Louise de la Motte
Aortic Aneurysm, Abdominal
Endurant Stent Graft System Post Approval Study (ENGAGE PAS)
The purpose of the study is to demonstrate the long term safety and effectiveness of the Endurant Stent Graft System for the endovascular treatment of infrarenal abdominal aortic aneurysms in a post-approval environment, through…
- Trial name
- NCT01379222
- Testing
- Endurant Stent Graft System
- Where
- 24 sites in United States
- Volunteers
- 178 people
- Sponsor
- Medtronic Cardiovascular
Complex Aortic Aneurysms, Thoracoabdominal Aneurysms
Complex Aortic Aneurysm Repair Using Physician Modified Endografts and Custom Made Devices
The purpose of this study is to evaluate the safety and efficacy of custom made devices, Zenith t-Branch devices and physician modification of FDA approved off-the-shelf endovascular grafts in the treatment of patients with…
- Conditions
- Complex Aortic Aneurysms, Thoracoabdominal Aneurysms, Pararenal Aneurysms, Juxtarenal Aneurysms
- Trial name
- CARPE-CMD (NCT02050113)
- Testing
- Custom Made Fenestrated or Branched Stent Graft
- Where
- United States
- Volunteers
- 600 people
- Sponsor
- Andres Schanzer
Aortic Aneurysm, Abdominal, Endovascular Procedures
Impact of Supra-renal Fixation of EVAR on Hemodynamics of Renal Arteries
The investigators conducted a bicentric prospective study to quantify the hemodynamic disturbances to the ostia of the renal arteries generated by the implantation EVAR with suprarenal fixation immediately postoperatively.
- Conditions
- Aortic Aneurysm, Abdominal, Endovascular Procedures, Renal Artery Stenosis
- Trial name
- IFIXEAR (NCT03594786)
- Testing
- endovascular aneurysm repair (EVAR)
- Where
- 2 sites in France
- Volunteers
- 70 people
- Sponsor
- Centre Hospitalier Universitaire de Besancon
Abdominal Aortic Aneurysm
Powerlink Bifurcated Stent Graft Long-Term Follow-up Study
Endologix Infrarenal Bifurcated Stent Graft Study
- Trial name
- NCT00543270
- Testing
- Powerlink infrarenal bifurcated stent graft delivery system, Open Surgery
- Where
- 14 sites in United States
- Volunteers
- 258 people
- Sponsor
- Endologix
PAD, Abdominal Aortic Aneurysm
Use of Fish Oil to Reduce Inflammation During Endovascular Abdominal Aortic Repair
The purpose of this study is to determine if high-dose PUFA supplementation in patients undergoing EVAR for infra-renal AAA reduces the peri-operative inflammation.
- Trial name
- Omega-EVAR (NCT03208920)
- Testing
- Pro-Omega
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- University of California, San Francisco
Physical Examination, Ultrasound Imaging
Abdominal Aorta Palpation With Point of Care Ultrasound Imaging Measurements
The goal of this observational study is to compare the measurements of abdominal aorta width via palpation and point of care ultrasound imaging in healthy individuals.
- Conditions
- Physical Examination, Ultrasound Imaging, Abdominal Aortic Aneurysm
- Trial name
- NCT06211946
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Aneurysm, Hypertension
The Effect of Angiotensin II Type 1 Receptor Antagonists on the Size and Expansion Rate of Abdominal Aortas in Hypertensive Patients
Abdominal aortic aneurysm (AAA) is a common disease that develops from degeneration of the aortic wall. The natural history of AAA is gradual expansion and if left untreated may result in rupture and death.
- Trial name
- NCT01670903
- Where
- 2 sites in Israel
- Volunteers
- 150 people
- Sponsor
- Sheba Medical Center
Aortic Aneurysm, Abdominal
Expanding Patient Applicability With Polymer Sealing Ovation Alto Stent Graft Investigational Device Exemption (IDE) Study
A prospective clinical evaluation of the effectiveness of the Ovation Alto Abdominal Stent Graft System when used in the treatment of subjects with abdominal aortic aneurysm (AAA).
- Trial name
- ELEVATE (NCT02949297)
- Testing
- Ovation Alto Abdominal Stent Graft System
- Where
- 13 sites in United States
- Volunteers
- 75 people
- Sponsor
- Endologix
Aortic Aneurysm, Abdominal, Aortic Diseases
Haemodynamic Response to Aortic Surgery
Open elective abdominal aortic surgery is a high risk procedure involving clamping of the aorta. Indications include abdominal aortic aneurysm (AAA) or aortic occlusive disease (AOD) causing lower limb ischaemia.
- Conditions
- Aortic Aneurysm, Abdominal, Aortic Diseases, Acute Kidney Injury
- Trial name
- NCT01704391
- Where
- Denmark
- Volunteers
- 18 people
- Sponsor
- Sygehus Lillebaelt
Abdominal Aortic Aneurysm
Relation betwEen Abdominal Aorta and Carotid Artery Responses to SymPathetic stimulatiON uSing duplEx Ultrasound
Abdominal aortic aneurysm (AAA) is a common vascular disease and associated with risk of rupture, but also with a high cardiovascular (CV) event rate. A key difficulty in AAA is predicting these life-threatening complications.
- Trial name
- RESPONSE (NCT04035252)
- Testing
- Carotid artery reactivity test (CAR-test)
- Where
- 2 sites in Netherlands
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Rijnstate Hospital
Thoracoabdominal Aortic Aneurysm, Without Mention of Rupture, Abdominal Aortic Aneurysm, Without Mention of Rupture
BGP Stent as Bridging Stent in FEVAR
The objective of this clinical investigation is to evaluate, in a controlled setting, the safety and performance of the BeGraft Peripheral (BGP) balloon expandable covered stent Graft System (Bentley InnoMed, Hechingen, Germany)…
- Trial name
- NCT03987035
- Testing
- BeGraft Peripheral (BGP) Stent Graft System as bridging stent
- Where
- 9 sites in Germany
- Volunteers
- 103 people
- Sponsor
- Marc Bosiers, MD
Aortic Aneurysm, Abdominal
ShOrt neCK AAA RAndomized Trial - ESAR and FEVAR: SOCRATES
The aim of this randomized study is to compare the safety and performance of EndoVascular Aneurysm Repair with ESAR using Endurant + Heli-FX™ EndoAnchor™ system and FEVAR using customizable grafts from Cook (Zenith Fenestrated…
- Trial name
- SOCRATES (NCT04503395)
- Testing
- ESAR treatment: Endograft + Heli-FX Endoanchor, FEVAR treatment : Fenestrated endograft
- Where
- 33 sites in United States, Austria and 8 more
- Volunteers
- 204 people
- Sponsor
- FCRE (Foundation for Cardiovascular Research and Education)