Clinical trials: Abdominal Aorta Aneurysm
Colchicine, Abdominal Aortic Aneurysm
Low-dose Colchicine Inhibit Abdominal Aortic Aneurysm Growth Trial
COIN trial is a a prospective, randomized, placebo-controlled, double-blind, multicenter clinical study. Approximately 230 patients with small abdominal aortic aneurysms (AAA) will be randomly allocated to low-dose colchicine…
- Conditions
- Colchicine, Abdominal Aortic Aneurysm, Progression
- Trial name
- COIN (NCT05361772)
- Testing
- colchicine
- Volunteers
- 230 people
- Sponsor
- Guangdong Provincial People's Hospital
Abdominal Aortic Aneurysm, Iliac Aneurysm
Global Iliac Branch Study
This project seeks to determine if certain anatomic factors, specifically tortuous and non-conformable iliac arteries, may predict device complications, including seal zone failure, type III endoleak, and occlusion.
- Trial name
- GIBS (NCT05607277)
- Testing
- Endovascular Repair of abdominal aortic aneurysms
- Where
- United States
- Volunteers
- 297 people
- Sponsor
- University of Wisconsin, Madison
Abdominal Aortic Aneurysm,, Small Abdominal Aortic Aneurysm
Cyclosporine A in Patients With Small Diameter Abdominal Aortic Aneurysms
Aneurysms of the aorta are dilatations of the main artery in the body that distributes blood to organs. Aneurysms expose patients to aortic rupture.
- Trial name
- ACA4 (NCT02225756)
- Testing
- Cyclosporine A
- Where
- France
- Volunteers
- 360 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Thoracic Aneurysm, Aneurysm Stent
The Effects of Anesthesia on Patients Undergoing Surgery for Repair of a Thoracoabdominal Aneurysm.
Alzheimer's disease represents a growing public health problem in developed countries. Although the pathogenesis is not clearly defined, accumulation of extracellular amyloid, neurofibrillary tangles and neuronal loss are the…
- Conditions
- Thoracic Aneurysm, Aneurysm Stent, Cardiopulmonary Bypass, Abdominal Aneurysm
- Trial name
- NCT01772537
- Testing
- Propofol, isoflurane
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- Johns Hopkins University
Aortic Aneurysm, Abdominal, Occlusive Disease of Artery of Lower Extremity
InterGard Synergy Post-Marketing Surveillance Study
The purpose of the study is to assess the performance and safety of the InterGard Synergy vascular graft.
- Trial name
- NCT01698671
- Testing
- InterGard Synergy Vascular Graft
- Where
- 3 sites in Austria, Germany
- Volunteers
- 50 people
- Sponsor
- Maquet Cardiovascular
Aortic Aneurysm
Role of Circulating MicroRNAs in Pathogenesis of Aneurysms of the Abdominal and Thoracic Aorta - Study "Micro AAA"
The objective of this study is to establish whether patients with aortic aneurysm, compared to general population, have higher levels of selected miRNAs and whether there is significant association between the level of miRNA in…
- Trial name
- NCT03090763
- Testing
- PCR and sequencing
- Where
- Czechia
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Charles University, Czech Republic
Appendicitis, Evidence of Cholecystectomy
Point of Care 3D Ultrasound for Various Applications: A Pilot Study
Summary 1. Purpose and Objective: The purpose of this study is to test the feasibility of rapid acquisition of point of care 3D ultrasound in obtaining abdominal and/or pelvic images.
- Conditions
- Appendicitis, Evidence of Cholecystectomy, Gallstones, Pregnancy, Ectopic
- Trial name
- NCT02831556
- Where
- United States
- Volunteers
- 174 people, healthy volunteers welcome
- Sponsor
- Duke University
Aortic Aneurysm
Patient Specific Biomechanical Modeling of Abdominal Aortic Aneurysm to Improve Aortic Endovascular Repair
This project is aiming at the integration of a biomechanical computer program with a guidance code to simulate the endovascular repair (EVAR) procedure of abdominal aortic aneurysm (AAA).
- Trial name
- AAA2D3DIII (NCT03481075)
- Testing
- Biomechanical computer program
- Where
- Canada
- Volunteers
- 20 people
- Sponsor
- Centre hospitalier de l'Université de Montréal (CHUM)
Rupture, Aortic, Aneurysm, Abdominal Aortic
Greek Study for Endovascular Repair of Ruptured Abdominal Aortic Aneuryms
This will be a non-randomized, prospective, observational multi-center research study. Its purpose will be to assess the mortality and outcome of EVAR in patients with rAAA.
- Conditions
- Rupture, Aortic, Aneurysm, Abdominal Aortic, Aneurysm, Ruptured
- Trial name
- GRAND (NCT04471181)
- Testing
- Endovascular repair of ruptured abdominal aortic aneurysm (EVAR) with Medtronic Endurant
- Where
- Greece
- Volunteers
- 157 people
- Sponsor
- Kostantinos Papazoglou
Abdominal Aneurysm, Aortic Aneurysm
Familial Risk of AAA in Sweden
The aim is to study the prevalence of abdominal aortic aneurysm in first degree relatives and the risk to develop AAA in individuals with heredity for AAA compared with the population ( without heredity for AAA).The study i based…
- Conditions
- Abdominal Aneurysm, Aortic Aneurysm, Aortic Aneurysm Abdominal
- Trial name
- NCT07577128
- Where
- Sweden
- Volunteers
- 900,000 people
- Sponsor
- Karolinska University Hospital
Abdominal Aorta Aneurysm
Circulating microRNAs and Degenerative Abdominal Aorta Aneurysm
Abdominal aortic aneurysm (AAA) is an aortic dilatation superior or equal to 30 mm with an estimated prevalence at 8% in men over 65 year-old.
- Trial name
- ACTA-miRNA (NCT03974958)
- Testing
- Tissue-library
- Where
- France
- Volunteers
- 106 people
- Sponsor
- Assistance Publique Hopitaux De Marseille
AAA - Abdominal Aortic Aneurysm
Perioperative Hypotension and Survival After Elective AAA Repair
Background: An abdominal aortic aneurysm (AAA) is a localized dilatation of the infrarenal aorta that, when it meets critical criteria, can rupture and cause a vital emergency, requiring immediate surgery with a mortality rate…
- Trial name
- AAAhypotension (NCT07511101)
- Where
- Netherlands
- Volunteers
- 511 people
- Sponsor
- Rijnstate Hospital
Aneurysm, Aneurysm Abdominal
Totally Percutaneous Approach to Endovascular Treatment of Aortic Aneurysms (PEVAR-PRO)
Purpose of the study is the evaluation of the applicability of the percutaneous technique through double Proglide and Pre-Close Technique to the treatment of complex aortic aneurysms with thoracic endoprosthesis (TEVAR)…
- Conditions
- Aneurysm, Aneurysm Abdominal, Aneurysm Thoracic, Aneurysm, Thoracoabdominal Aortic
- Trial name
- PEVAR-PRO (NCT03484013)
- Where
- Italy
- Volunteers
- 320 people
- Sponsor
- IRCCS San Raffaele
Abdominal Aortic Aneurysm
Advanced MRI in AAA
This study aims to determine whether advanced MRI sequences can provide robust and clinically relevant information about abdominal aortic aneurysms (AAAs).
- Trial name
- NCT03138434
- Where
- Netherlands
- Volunteers
- 31 people
- Sponsor
- Ron Balm
AAA - Abdominal Aortic Aneurysm
Aneurysm Treatment Using the Heli-FX™ EndoAnchor™ System China Study(ATHENA)
To evaluate the safety and effectiveness of the Heli-FX EndoAnchor system in AAA subjects who without augmented radial fixation and/or sealing due to an endoleak or migration are at high risk for aneurysm-related complications or…
- Trial name
- ATHENA (NCT07754318)
- Testing
- Heli-FX EndoAnchor System
- Where
- China
- Volunteers
- 142 people
- Sponsor
- Medtronic Cardiovascular
Abdominal Aortic Aneurysm
DynaCT Imaging in EVAR: Comparing Clinical Benefit of DynaCT to Multidetector CT as the Current Gold Standard.
The aim of this study is to evaluate a new way to create CT-like images during intra-operative procedures. We want to prove that the quality and information received from DynaCT is satisfactory in implementing stent-graft in…
- Trial name
- NCT00264862
- Testing
- DynaCT
- Where
- Norway
- Volunteers
- 20 people
- Sponsor
- Norwegian University of Science and Technology
Abdominal Aortic Aneurysms (AAA)
A Clinical Investigational Study of Ankura™ II AAA, IE and AE Stent Graft System for Endovascular Treatment of Abdominal Aortic Aneurysm
The objective of this clinical investigational study is to evaluate the safety and efficacy of the Ankura™ II AAA, AE Stent Graft System and the large-size Ankura™ II IE Stent Graft System (i.e., IE stent grafts with distal…
- Trial name
- NCT07754240
- Testing
- Ankura™ II Abdominal Aortic Stent Graft System
- Where
- Bulgaria
- Volunteers
- 45 people
- Sponsor
- Lifetech Scientific (Shenzhen) Co., Ltd.
AAA, AAA - Abdominal Aortic Aneurysm
JAGUAR Trial: ObJective Analysis to GaUge EVAR Outcomes Through Randomization
Prospective, randomized, multi-center study designed to evaluate the outcomes of commercially available contemporary EVAR in a real-world population.
- Trial name
- JAGUAR (NCT05064540)
- Testing
- Alto Abdominal Stent Graft System, FDA Approved EVAR AAA Graft Systems
- Where
- 29 sites in United States
- Volunteers
- 450 people
- Sponsor
- Endologix
Aortic Aneurysm, Abdominal
Suture-Tight™ First-in-Human Safety and Performance Study
Single center, open label, prospective, single-arm, first-in-human (FIH), pre-market clinical study with the objective of validating the safety and performance of the Suture-Tight™ Suture Delivery System in an EVAR procedure.
- Trial name
- Suture-Tight™ (NCT05812768)
- Testing
- Suture-Tight Suture Delivery System
- Where
- Australia
- Volunteers
- 6 people
- Sponsor
- Vesteck, Inc.
Abdominal Aortic Aneurysm, Endovascular Procedures
Standardization of Physician-Modified Stent Grafts for Abdominal Aortic Aneurysms
This study explores the use of physician-modified stent grafts (PMSGs) for treating abdominal aortic aneurysms that are unsuitable for open surgery or standard endovascular grafts.
- Conditions
- Abdominal Aortic Aneurysm, Endovascular Procedures, Stents, Vascular Surgical Procedures
- Trial name
- RESTORE (NCT06585215)
- Where
- Switzerland
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Ente Ospedaliero Cantonale, Bellinzona