Clinical trials: Abdominal Aortic
Type II Endoleak, Abdominal Aortic Aneurysm Enlargement
Deep-learning Predictors of Abdominal Aortic Aneurysm Enlargement in Type II Endoleaks After Endovascular Aortic Repair: The RADAR Study
Background and rationale: Abdominal aortic aneurysm (AAA) is a weakening and enlargement of the main artery in the abdomen. Endovascular aneurysm repair (EVAR) is a minimally invasive treatment used to repair an AAA.
- Trial name
- RADAR (NCT07783126)
- Testing
- Artificial intelligence model analyzing preoperative CT angiography
- Volunteers
- 1,250 people
- Sponsor
- Ente Ospedaliero Cantonale, Bellinzona
Abdominal Aneurysm, Selenium Deficiency
Selenium Levels in Patients With Abdominal Aneurysm
Retrospective study comparing the selenium level in patients with abdominal aortic aneurysm with the selenium level in patients in the control group, i.e., patients without aneurysmal changes of the abdominal aorta.
- Trial name
- NCT07236281
- Where
- Slovakia
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Comenius University
Graft Occlusion, Vascular
Total Laparoscopic Versus Open Aortic Surgery for Abdominal Aortic Disease
This prospective study was designed to analyse the postoperative and long-term outcomes of total laparoscopic vs. open surgical repair of infra-renal abdominal aortic occlusive disease (AOD) and infra-renal aortic aneurysmal…
- Trial name
- NCT02325700
- Testing
- Aortic repair
- Volunteers
- 228 people
- Sponsor
- University of Poitiers
Abdominal Aortic Aneurysm
CRD007 for the Treatment of Abdominal Aorta Aneurysm (The AORTA Trial)
This is an investigation of the efficacy and safety of CRD007 compared to placebo in the treatment of patients with abdominal aortic aneurysm.
- Trial name
- NCT01354184
- Testing
- CRD007
- Where
- 15 sites in Denmark, Sweden and 1 more
- Sponsor
- RSPR Pharma AB
Abdominal Aortic Aneurysm, Stress
Sex-specific Differences in the Stress Response to Abdominal Aortic Aneurysm Repair
It is recognised that women are at greater risk of death, complications and longer hospital stay following intact abdominal aortic aneurysm (AAA) repair, and the reason for this is not yet established.
- Conditions
- Abdominal Aortic Aneurysm, Stress, Surgery
- Trial name
- SSStressAAA (NCT05230264)
- Testing
- Elective AAA Repair
- Where
- United Kingdom
- Volunteers
- 60 people
- Sponsor
- Imperial College London
Abdominal Aortic Aneurysm
Evaluation of the Impact of Prehabilitation on Recovery Following Open Surgery for Abdominal Aortic Aneurysm
This is a pilot, prospective, randomized control trial that aim to provide a first estimation of the 3-month post-operative variation in the functional recovery of patients who benefited from an outpatient pre-habilitation…
- Trial name
- EPOP-AORTA (NCT05375292)
- Testing
- PREHABILITATION
- Where
- France
- Volunteers
- 60 people
- Sponsor
- University Hospital, Toulouse
Aorta Disease, Aorta Aneurysm
Assess Abdominal Aortic Diameter in Females
Female subjects aged 50 years or older will be enrolled. Biometric data (measurements) of the aorta and iliac vessels, demographic data, pathophysiological history, and data relating to menarche, pregnancy/infertility, and…
- Trial name
- AFRODITE (NCT07487961)
- Where
- Italy
- Volunteers
- 652 people, healthy volunteers welcome
- Sponsor
- Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico
Abdominal Aneurysm, Aortic Aneurysm
Familial Risk of AAA in Sweden
The aim is to study the prevalence of abdominal aortic aneurysm in first degree relatives and the risk to develop AAA in individuals with heredity for AAA compared with the population ( without heredity for AAA).The study i based…
- Conditions
- Abdominal Aneurysm, Aortic Aneurysm, Aortic Aneurysm Abdominal
- Trial name
- NCT07577128
- Where
- Sweden
- Volunteers
- 900,000 people
- Sponsor
- Karolinska University Hospital
Aortic Aneurysm, Abdominal, Juxtarenal Aortic Aneurysm
Zenith® Fenestrated+ Clinical Study
The Zenith® Fenestrated+ Endovascular Graft Clinical Study will assess the safety and effectiveness of the Zenith® Fenestrated+ Endovascular Graft (ZFEN+) in combination with the BeGraft Balloon-Expandable FEVAR Bridging Stent…
- Conditions
- Aortic Aneurysm, Abdominal, Juxtarenal Aortic Aneurysm, Extent IV Thoracoabdominal, Pararenal Aneurysm
- Trial name
- NCT04875429
- Testing
- Zenith Fenestrated+ Endovascular Graft in combination with the BeGraft Balloon-Expandable FEVAR Bridging Stent Graft System and Unibody2
- Where
- 33 sites in United States, United Kingdom
- Volunteers
- 105 people
- Sponsor
- Cook Research Incorporated
Aortic Aneurysm, Abdominal, Popliteal Artery Aneurysm
Venous Distension in Patients With Aneurysmatic Arterial Disease
The aim of the study is to assess if venous distension in patients with aneurysmatic arteriopathy is higher compared to patients with peripheral arterial occlusive disease (PAOD) and in controls.
- Conditions
- Aortic Aneurysm, Abdominal, Popliteal Artery Aneurysm, Peripheral Arterial Occlusive Disease, Vascular Diseases
- Trial name
- NCT02867501
- Volunteers
- 98 people, healthy volunteers welcome
- Sponsor
- Kantonsspital Baselland Bruderholz
Abdominal Aortic Aneurysm (AAA)
Image Fusion of Preprocedural CTA With Real Time Fluoroscopy to Enhance EVAR Repair
Abdominal Aortic Aneurysm (AAA) is a potentially life threatening condition. If the aneurysm ruptures, the mortality can be as high as 80%.
- Trial name
- NCT02295137
- Testing
- Using pre-procedural CTA to guide advanced EVAR procedure
- Where
- Canada
- Volunteers
- 20 people
- Sponsor
- University Health Network, Toronto
Abdominal Aortic Aneurysm, Iliac Aneurysm
Global Iliac Branch Study
This project seeks to determine if certain anatomic factors, specifically tortuous and non-conformable iliac arteries, may predict device complications, including seal zone failure, type III endoleak, and occlusion.
- Trial name
- GIBS (NCT05607277)
- Testing
- Endovascular Repair of abdominal aortic aneurysms
- Where
- United States
- Volunteers
- 297 people
- Sponsor
- University of Wisconsin, Madison
Abdominal Aortic Aneurysm
Female Aneurysm Screening STudy
An abdominal aortic aneurysm (AAA) is a swelling of the main blood vessel (aorta) in the abdomen. If the swelling gets too large the aorta can burst and this is usually fatal.
- Trial name
- FAST (NCT03277781)
- Testing
- Screening
- Where
- United Kingdom
- Volunteers
- 5,612 people
- Sponsor
- University of Leicester
Postimplantation Syndrome, Endovascular Abdominal Aortic Aneurysm Repair (EVAR)
Post-Implantation Syndrome and Laboratory Markers Following EVAR and TEVAR
The aim of this observational study is to investigate the relationship between postimplantation syndrome (PIS) and laboratory inflammatory parameters following endovascular aortic repair (EVAR/TEVAR).
- Conditions
- Postimplantation Syndrome, Endovascular Abdominal Aortic Aneurysm Repair (EVAR), Thoracic Endovascular Aortic Repair
- Trial name
- PIS and EVAR (NCT07014839)
- Testing
- Endovascular Aortic Intervention
- Where
- 3 sites in Turkey (Türkiye)
- Volunteers
- 300 people
- Sponsor
- Ataturk University
Aortic Aneurysm, Abdominal, Arterial Occlusive Diseases
Plasma Transfusion in Major Vascular Surgery
BACKGROUND Major blood loss is frequent in open repair of ruptured and intact abdominal aortic aneurysm (AAA) as well as in aorto-bifurcated prosthesis insertion due to aortoiliac occlusive disease.
- Trial name
- NCT04514575
- Testing
- Plasma transfusion
- Where
- Denmark
- Volunteers
- 17,000 people
- Sponsor
- Naestved Hospital
Abdominal Aortic Aneurysm, Surgery
ACT Guided Heparinization During Open Abdominal Aortic Aneurysm Repair.
Aim of the ACTION-1 study is to determine whether ACT guided heparinization decreases thrombo-embolic complications (TEC) and mortality after elective open AAA surgery, without causing more bleeding complications.
- Conditions
- Abdominal Aortic Aneurysm, Surgery, Arterial Disease
- Trial name
- ACTION-1 (NCT04061798)
- Testing
- ACT guided heparinization, 5 000 IU of heparin
- Where
- 22 sites in Germany, Netherlands
- Volunteers
- 294 people
- Sponsor
- Dijklander Ziekenhuis
Abdominal Aortic Aneurysms
China Post-market Study of the INCRAFT® AAA Stent Graft System in Subjects With Abdominal Aortic Aneurysms (INITIATION)
INITIATION is a postmarket clinical follow-up study in China. The purpose of the study is to continue to evaluate the safety and effectiveness/performance of Incraft in subjects with abdominal aortic aneurysms requiring…
- Trial name
- NCT03965364
- Testing
- INCRAFT
- Where
- China
- Sponsor
- Cordis US Corp.
Abdominal Aortic Aneurysm, Pulse Wave Analysis
The Effect of Surgery on Central Aortic Pressure & haEmodynamics Study
The present study will investigate the effect of artificially stiffening the aorta by means of an aortic stent on central aortic haemodynamics (CAH).
- Conditions
- Abdominal Aortic Aneurysm, Pulse Wave Analysis, Risk
- Trial name
- ESCAPE (NCT02493296)
- Testing
- This observational study will not entail an intervention.
- Where
- United Kingdom
- Volunteers
- 146 people
- Sponsor
- University of Leicester
Abdominal Aortic Aneurysm, Image
AAA-CTA Cohort Registry
The aim of this study is to investigate the measurement of abdominal aortic aneurysm by computed tomography angiography. The research will collected the results of computed tomography angiography from inpatient, emergency, and…
- Trial name
- NCT07039825
- Testing
- Computed tomography angiography
- Where
- China
- Volunteers
- 1,000 people
- Sponsor
- RenJi Hospital
Aortic Aneurysms
Medical & Economical Evaluation of Fenestrated & Branched Stent-grafts to Treat Complex Aortic Aneurysms
The aim of this study is to prospectively compare the perioperative mortality severe morbidity and the costs of endovascular versus conventional surgical repair of pararenal, supra-renal and type 4 THORACO-abdominal aortic…
- Trial name
- Windows1 (NCT01168037)
- Testing
- Endovascular aortic repair with branched/fenestrated stent-graft, Open Surgical Repair
- Where
- France
- Volunteers
- 270 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris