Clinical trials: Abdominal Delivery
Post-spinal Hypotension, Cesarean Section
Epinephrine Infusion for Prophylaxis Against Maternal Hypotension During Caesarean Section
Maternal hypotension after spinal block is a common complication after subarachnoid block in this population. The incidence of maternal hypotension is nearly 60% when prophylactic vasopressors are not used.
- Trial name
- NCT05051150
- Testing
- Epinephrin 0.03, Epinephrin 0.05, Epinephrin 0.07
- Where
- Egypt
- Volunteers
- 18 people
- Sponsor
- Kasr El Aini Hospital
Cesarean Section, Parturition
The Experience of Fathers and Mothers in Relation to the Presence of the Father at the Birth in the Case of a Planned Caesarean Section: a Qualitative Phenomenological Study
Pregnancy and childbirth represent a crucial transition for couples, involving significant psychological and emotional adaptation.
- Trial name
- "PARENTS" (NCT07152743)
- Volunteers
- 60 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Constipation, Abdominal Pain
Pilot Study of the Effect of Lactulose on Post Caesarean Section Constipation
Constipation following elective Caesarean sections (CS) is a common problem experienced by up to 50% of patients (1). The causes for this are multifactorial and include manipulation of the bowel during surgery, immobilisation and…
- Conditions
- Constipation, Abdominal Pain, Nausea, Vomiting
- Trial name
- NCT01295138
- Testing
- Lactulose
- Where
- United Kingdom
- Volunteers
- 30 people
- Sponsor
- NHS Fife
Placenta Previa, Placenta Accreta
ROTEM in Patients With Placenta Previa
The rotational thromboelastogram (ROTEM) test can be performed on patients with placenta previa/accreta/increta/percreta who have a high likelihood of massive bleeding, and the predictors can be identified by comparing the…
- Conditions
- Placenta Previa, Placenta Accreta, Placenta Increta, Placenta Percreta
- Trial name
- NCT04213755
- Testing
- ROTEM
- Where
- South Korea
- Volunteers
- 100 people
- Sponsor
- Seoul National University Bundang Hospital
Cesarean Wound Disruption With Postnatal Complication
Impact of Preoperative Bathing on Post Caesarean Section Surgical Site Infection
Surgical site infection (SSI) is the commonest hospital-acquired infection globally, and prevalence is much higher in the low-income countries. Caesarean delivery carries a 5-20 fold risk for developing postpartum sepsis.
- Trial name
- SSI-MUST (NCT03544710)
- Testing
- preoperative bathing with antiseptic
- Where
- Uganda
- Volunteers
- 96 people
- Sponsor
- Mbarara University of Science and Technology
Acute Pain Management, Caesarean Section
Transverse Abdominis Plane (TAP) Block Versus Transversalis Fascia Plane Block (TFPB) After Cesarean Delivery
Postoperative analgesia treatment methods are applied to the living in the operating room. It is a routine part of the process of these applications. It is necessary from medical and ethical perspectives.
- Trial name
- NCT06939725
- Testing
- Transversus abdominis plane (TAP) block, Transversalis Fascia Plane Block
- Where
- Turkey (Türkiye)
- Volunteers
- 67 people
- Sponsor
- Samsun University
Complication, Postoperative
Early Initiation of Oral Feeding Versus Traditional Feeding Post Caesarean Section
Early initiation of oral feeding, within 6-12 hours post-caesarean section, has been noticed to be well tolerated by patients and helps them recover fast.
- Trial name
- NCT06539117
- Testing
- Early feeding post caesarean section
- Where
- Nigeria
- Volunteers
- 153 people, healthy volunteers welcome
- Sponsor
- Darlington-Peter Chibuzor Ugoji
Post-Dural Puncture Headache
The Influence of Needle Diameter on Post Dural Puncture Headache
The purpose of this study is to determine whether injection needle pen point type 'PP Gauge 25' should be recommended as a primary choice of needle (in stead of 'PP Gauge 27') for healthy pregnant women who at delivery (vaginal…
- Trial name
- NCT02827058
- Testing
- G25 pencil point needle, G27 pencil point needle
- Where
- 3 sites in Norway
- Volunteers
- 65 people
- Sponsor
- Helse Nord-Trøndelag HF
Cesarean Section Complications
Short Versus Standard Post-operative Stay After Elective Cesarean Delivery
After major open abdominal surgery, transient paralytic ileus usually follows. It has been suggested that stimulation of pain fibers, excessive sympathetic tone, and the release of inhibitory neurotransmitters from bowel wall…
- Trial name
- NCT03355378
- Testing
- gum chewing
- Where
- Egypt
- Volunteers
- 200 people
- Sponsor
- Assiut University
Cesarean Section
Diclofenac vs. Ropivacaine for Cesarean Section
A prospective, randomized, double blind study designed to investigate analgesic efficacy of wound infusion using diclofenac or ropivacaine following Cesarean section performed via a Pfannenstiel incision.
- Trial name
- NCT00801528
- Testing
- Ropivacaine, Diclofenac, Water for injection
- Where
- Israel
- Volunteers
- 75 people
- Sponsor
- Meir Medical Center
Surgical Wound Infection
Clorhexidine Versus Povidone for the Prevention of Surgical Site Infection After Cesarean Section
Many solutions are used for cleaning the skin of a patient previous to a surgery. Although the efficacy of clorhexidine has been proved in other surgical procedures, there is only a retrospective study in cesarean section (they…
- Trial name
- NCT01741649
- Testing
- Clorhexidine, Povidone
- Where
- Panama
- Volunteers
- 800 people
- Sponsor
- Saint Thomas Hospital, Panama
Post Partum Hemorrhage
Efficacy of Tranexamic Acid in Preventing Postpartum Haemorrhage After Elective Caesarean Section
Background Postpartum haemorrhage (PPH) is a major cause of maternal mortality worldwide accounting for 25% of maternal deaths. In Zimbabwe PPH is the second most common cause of death.
- Trial name
- NCT03463993
- Testing
- Tranexamic Acid, Oxytocin
- Where
- 2 sites in Zimbabwe
- Volunteers
- 506 people, healthy volunteers welcome
- Sponsor
- University of Zimbabwe
Cesarean Section Complications, ERAS
Outcomes of Enhanced Recovery After Cesarean (ERAC) Protocol
In recent years, a set of evidence-based recommendations called Enhanced Recovery After Surgery (ERAS) is being applied for care of cesarean sections.
- Trial name
- NCT05786352
- Testing
- ERAS protocol
- Where
- Turkey (Türkiye)
- Volunteers
- 1,200 people
- Sponsor
- Zeynep Kamil Maternity and Pediatric Research and Training Hospital
Pain Relief
The Effect of Pre-incisional Local Xylocaine Injection on Post Operative Pain and Scar Formation After Cesarean Section
This study will examine whether pre-incision infiltration of the skin cut site can attenuate post operative pain after a cesarean section.
- Trial name
- NCT00914498
- Testing
- Local, pre-incisional injection of 20 ml 1% xylocaine
- Where
- Israel
- Volunteers
- 120 people
- Sponsor
- The Baruch Padeh Medical Center, Poriya
Pregnancy Related, Hypotension
The Effect of HPI to Reduce Intraoperative Hypotension in Caesarean Sections
During caesarean section, blood pressure variations especially a reduction in blood pressure (or hypotension) can bring harmful effects to mother and baby. This usually occurs after spinal anaesthesia is administered.
- Conditions
- Pregnancy Related, Hypotension, Maternal-Fetal Relations, Cesarean Section Complications
- Trial name
- NCT06892665
- Testing
- Hypotension prediction index, Non invasive Blood Pressure Monitoring
- Where
- Malaysia
- Volunteers
- 100 people
- Sponsor
- National University of Malaysia
Pruritus Caused by Drug
Ondansetron Use for Preventing Pruritus in Patients Undergoing Cesarean Section
Opioids are often added with a local anesthetic to enhance the duration and quality of spinal anesthesia for cesarean delivery patients.
- Trial name
- NCT06297499
- Testing
- Ondansetron 8mg
- Where
- United States
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Wayne State University
Complications; Cesarean Section, Pregnancy
Mobius® Post-cesarean Pain Randomized Control Trial
The purpose of this study is to investigate whether the use of the Mobius® retractor decreased post-operative pain after cesarean section verses conventional retractor use.
- Trial name
- NCT00685932
- Testing
- Mobius Retractor
- Where
- United States
- Volunteers
- 154 people
- Sponsor
- Abbey Hardy-Fairbanks
Cesarean Section, Obesity
Comparison of Tissue Retractors During Cesarean Delivery in Obese Women
This is a randomized controlled trial comparing the use of the Mobius™ retractor to the use of traditional metal retraction instruments in non-urgent cesarean deliveries of obese women.
- Trial name
- NCT00358592
- Testing
- Mobius™ retractor, traditional metal retraction instruments
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Thomas Jefferson University
Pregnancy Related, Cesarean Delivery
Accupressure of P6 to Reduce Nausea During Cesarean Section
The purpose of this study is to evaluate if the addition of P6 pressure point stimulation as opposed to sham-point stimulation will decrease intraoperative and postoperative nausea and vomiting (IONV and PONV) for patients…
- Conditions
- Pregnancy Related, Cesarean Delivery, Nausea, Vomiting
- Trial name
- NCT04799587
- Testing
- Magnet at P6, Magnet applied to arm not at P6 pressure point.
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- Northwestern University
Cesarean Section Complications, Spinal Anesthetic Toxicity
Comparison of Vasopressor Boluses for Management of Hypotension After Spinal Anesthesia
In this study the investigators will compare the efficacy and side effects of two doses of norepinephrine bolus (6 mcg and 10 mcg) in management of maternal hypotensive episode after subarachnoid block during Cesarean delivery.
- Trial name
- NCT03712111
- Testing
- Norepinephrine 6 mcg, Norepinephrine 10 mcg, Bupivacaine Hydrochloride
- Where
- Egypt
- Volunteers
- 86 people
- Sponsor
- Cairo University
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