Clinical trials: Abdominal Injuries
Surgical Wound Infection, Wound; Abdomen, Abdominal Wall
Surgical Site Infection Rate After Intra-Abdominal Surgery Using Negative Pressure Wound Therapy at Initial Closure
The goal of this study is to present a large single-institution experience reporting surgical site infection rates in patients who have undergone intra-abdominal surgery followed by wound closure with Negative Pressure Wound…
- Conditions
- Surgical Wound Infection, Wound; Abdomen, Abdominal Wall, Surgery
- Trial name
- NCT01924884
- Where
- United States
- Volunteers
- 400 people
- Sponsor
- Johns Hopkins University
Trauma Splenic, Trauma Abdomen
The Role of Prehospital eFAST in Accelerating Time to Diagnostics or Definitive Treatment in the Emergency Department
Actual literature has demonstrated that prehospital extended focused assessment sonography for trauma (eFAST) could impact on logistic and treatment decisions such as mode of transportation and choice of hospital destination.
- Conditions
- Trauma Splenic, Trauma Abdomen, Liver Injury
- Trial name
- NCT04934384
- Testing
- prehospital extended focused assessment sonography for trauma
- Where
- Italy
- Volunteers
- 199 people
- Sponsor
- Azienda Usl di Bologna
Postoperative Pain
Postoperative Pain Relief After Major Abdominal Gynecological Surgery
The aim of our study was to compare the effects of Lomber Epidural Analgesia (LEA), Transversus Abdominis Plane (TAP) block and Local Anesthetic Infiltration (LAI) on postoperative morphine consumption, time to first recue…
- Trial name
- NCT05845385
- Testing
- lumbar epidural analgesia with bupivacaine, transversus abdominis plane block with bupivacaine, wound infiltration with bupivacaine
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 81 people, healthy volunteers welcome
- Sponsor
- Cukurova University
Incisional Hernia, Wound Dehiscence
Hernia After Colorectal Cancer Surgery
Defects in the abdominal wall (incisional hernia) is a frequent negative outcome after surgery. Reinforcing the incision with mesh seem to lower the incidence but in surgery that includes bowel resection a simple alternative…
- Conditions
- Incisional Hernia, Wound Dehiscence, Wound Complication, Quality of Life
- Trial name
- Rein4CeTo1 (NCT03390764)
- Testing
- 4:1 closure group, RTL plus 4:1 closure group
- Where
- Sweden
- Volunteers
- 152 people
- Sponsor
- Skane University Hospital
Wound Dehiscence, Incision
Pediatric Post-operative Abdominal Wound Dehiscence in Association With Midline vs Other Incisions: A Prospective Cohort Study
This study is designed to see different abdominal incisions complication among neonates, infants and children and to find risk factors for developing wound dehiscence
- Trial name
- NCT05963477
- Testing
- laparatomy
- Where
- Afghanistan
- Volunteers
- 270 people
- Sponsor
- French Medical Institute for Mothers and Children
Surgical Site Infection, Surgery--Complications
Prophylaxis of Surgical Wound Infection With Topical Antibiotics
Surgical site infection (SSI) is the main complication of surgery. The prevention of superficial SSI by topical prophylaxis is controversial.
- Conditions
- Surgical Site Infection, Surgery--Complications, Colorectal Surgery, Cesarean Section; Infection
- Trial name
- NCT04476212
- Testing
- Topical antibiotic prophylaxis
- Where
- Spain
- Volunteers
- 560 people
- Sponsor
- Hospital de Granollers
Incisional Hernia, Surgical Site Infection
Prophylactic Mesh Reinforcement for Stoma Closure
In the current work we are aiming to compare between the mesh-reinforced stoma closure and the anatomical closure in terms of the risk of developing surgical site incisional hernia (SSIH),incidence of surgical site infection …
- Conditions
- Incisional Hernia, Surgical Site Infection, Postoperative Pain, Hospital Stay, Length of Stay in Hospital From Surgery to Discharge
- Trial name
- OASIS (NCT06157645)
- Testing
- Prolene mesh
- Where
- Egypt
- Volunteers
- 62 people
- Sponsor
- Assiut University
Laparotomy Closure After Abdominal Surgery
Comparing Delayed vs Primary Wound Closure After Emergency Laparotomy: Impact on Infection, Healing, and Hospital Stay
The purpose of this study is to find out which type of wound closure after emergency abdominal surgery leads to fewer wound infections and better recovery: closing the wound immediately after surgery (called primary closure) or…
- Trial name
- NCT07142395
- Testing
- Immediate skin closure, Delayed primary closure
- Where
- Pakistan
- Volunteers
- 82 people
- Sponsor
- Bkahtawar Amin Medical and Dental College Multan
Surgical Wound Infection
Comparison of Surgical Site Infection Rate Between Primary, Delayed Primary and Vacuum Assisted Closures.
The objective of the study is to compare infection rates between primary, delayed primary and vacuum assisted closures in contaminated and dirty/infected laparotomy wounds.
- Trial name
- NCT02649543
- Testing
- Primary Closure, Vacuum Assisted Closure, Delayed Primary Closure
- Where
- Mexico
- Volunteers
- 81 people
- Sponsor
- Eduardo Flores Villalba
Sepsis
Indocyanine Clearance Rate and Septic Liver Injury
Liver injury is a complication of sepsis and septic liver injury has adverse impact upon the outcome. As a measurement for liver function, Plasma clearance rate of indocyanine green (PDR-ICG) always decreased during the early…
- Trial name
- NCT01447836
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Sun Yat-sen University
Third Degree Burn, Second Degree Burn
Diagnostic of Infections Following Major Abdominal Surgery and Burn Injury
This study was designed to investigate, if new biomarkers may improve the early diagnostic of infections following major abdominal surgery and severe burn injuries.
- Trial name
- Earlygnost (NCT01055587)
- Where
- Germany
- Volunteers
- 120 people
- Sponsor
- Klinikum St. Georg gGmbH
Wound Infection
Antiseptic Sutures and Wound Infection
The aim of this study was to ascertain if the use of Vicryl plus® reduced the number of wound infections after transverse laparotomy comparing to polydioxanon suture.
- Trial name
- NCT00932503
- Testing
- Vicryl plus
- Where
- Germany
- Volunteers
- 839 people
- Sponsor
- University Hospital, Saarland
Wound Heal
Performance, Safety and Efficacy of PICO Device.
The study is being conducted to evaluate the safe and effective use of the PICO 7 system in surgically closed incision sites and wounds requiring closure by skin graft or flap as part of the PMCF plan for this product, for the…
- Trial name
- NCT03698968
- Testing
- Negative Pressure Wound Therapy
- Where
- 11 sites in Switzerland, United Kingdom
- Volunteers
- 50 people
- Sponsor
- Smith & Nephew, Inc.
Surgical Site Infection, Obesity
SUpPress SSI - Single Use Negative Pressure Wound Therapy (NPWT) to Reduce Surgical Site Infections
Our goal is to provide data that will give surgeons and hospitals clear recommendations on the use of NPWT for Cesarean section, abdominal hysterectomy and colon surgeries in patients with diabetes and/or obesity.
- Conditions
- Surgical Site Infection, Obesity, Diabetes, Cesarean Section Complications
- Trial name
- SUpPressSSI (NCT03816293)
- Testing
- Negative Pressure Wound Therapy
- Where
- 5 sites in United States
- Volunteers
- 3,680 people
- Sponsor
- University of Illinois at Chicago
Abdominal Aortic Aneurysm, Abdominal Aortic Aneurysm, Ruptured
Aortic Size and Height Indices in Abdominal Aortic Aneurysms
The goal of this observational study is to learn whether adjusting abdominal aortic aneurysm (AAA) size for body size helps distinguish ruptured from intact aneurysms better than maximum aneurysm diameter alone.
- Conditions
- Abdominal Aortic Aneurysm, Abdominal Aortic Aneurysm, Ruptured, Abdominal Aortic Aneurysm Without Rupture
- Trial name
- AASI (NCT07893704)
- Where
- Mexico
- Volunteers
- 2,000 people
- Sponsor
- Tecnologico de Monterrey
Gastrostomy
Transversus Abdominis Plane Block on Stress Response
This study evaluates the effect of transversus abdominis plane(TAP) block combined with general anesthesia on perioperative stress response in patients undergoing radical gastrectomy.
- Trial name
- NCT03035916
- Testing
- Transversus abdominis plane block, Epidural anesthesia, control
- Where
- China
- Volunteers
- 91 people
- Sponsor
- Jilin University
Hernia, Wound Infection
Suture Techniques to Reduce the Incidence of The inCisional Hernia
The objective of the study is reduction of the incidence of the most frequent complication of abdominal surgery, incisional hernia.
- Conditions
- Hernia, Wound Infection, Burst Abdomen, Pain
- Trial name
- STITCH (NCT01132209)
- Testing
- Closure of the abdominal wall after midline incisions
- Where
- Netherlands
- Volunteers
- 576 people
- Sponsor
- Erasmus Medical Center
Wound Healing and Prevention
Performance, Safety and Efficacy of NPWT Device
Smith \& Nephew are assessing a new investigational single use NPWT system.
- Trial name
- NCT04102865
- Testing
- Negative-Pressure Wound Therapy (NPWT)
- Where
- 8 sites in United Kingdom
- Volunteers
- 90 people
- Sponsor
- Smith & Nephew, Inc.
Epithelial Ovarian Cancer, Fallopian Tube Carcinoma
Hyperthermic Intraoperative Intraperitoneal Chemotherapy of Recurrent Ovarian Cancer - A Feasibility Study
Most studies performing hyperthermic intraoperative intraperitoneal chemotherapy dose the cytotoxic drugs according to the body surface (like 50 mg/m² cisplatin) in analogy to systemic, intravenous chemotherapy (usually using the…
- Trial name
- NCT00968799
- Testing
- Hyperthermic intraoperative intraperitoneal chemotherapy, Cytoreduction, Cisplatin
- Where
- Switzerland
- Volunteers
- 6 people
- Sponsor
- Cantonal Hospital of St. Gallen
Ventilator-Induced Lung Injury
Transpulmonary Pressure Under Stressing Conditions
Study aims to prospectively evaluate if the pressures normally applied during mechanical ventilation in laparoscopic surgery induce stress on the pulmonary wall.
- Trial name
- NCT03746236
- Where
- 2 sites in Italy
- Volunteers
- 20 people
- Sponsor
- Regina Elena Cancer Institute