Clinical trials: Abdominal Neoplasm, open to volunteers
Peritoneal Carcinomatosis, Gastric Cancer
Oncological Benefits of Pressured Intraperitoneal Aerosol Chemotherapy (PIPAC) in Patients With T3-4 Gastric Cancer Cyt-
Stomach cancer is recognized as the third leading cause of death of cancer patients worldwide. Despite the radical treatment carried out, the progression of gastric cancer occurs in 30-40% of patients.
- Trial name
- GASPACCO (NCT04595929)
- Testing
- Staging laparoscopy, 5-Fluorouracil, Leucovorin
- Where
- Russia
- Volunteers
- 304 people
- Sponsor
- St. Petersburg State Pavlov Medical University
Appendix Cancer, Pseudomyxoma Peritonei
The Appendix Cancer PMP Research Foundation Natural History Study/Patient Registry
ACPMP's first-ever patient-powered global patient registry/natural history study collects patient and caregiver information and data to fuel clinical trials and drive breakthroughs for appendix cancer and PMP.
- Trial name
- NCT07769346
- Where
- United States
- Volunteers
- 10,000 people
- Sponsor
- Appendix Cancer Pseudomyxoma Peritonei Research Foundation
Childhood Malignant Solid Neoplasm, Childhood Malignant Thoracic Neoplasm
An Imaging Agent (Pafolacianine) for Identifying Lesions in Pediatric Patients With Primary or Metastatic Solid Tumors
This phase III trial studies how well pafolacianine works for identifying cancerous lesions in children and adolescent patients with primary solid tumors or solid tumors that have spread from where they first started (primary…
- Conditions
- Childhood Malignant Solid Neoplasm, Childhood Malignant Thoracic Neoplasm, Malignant Abdominal Neoplasm, Malignant Neck Neoplasm
- Trial name
- NCT06915727
- Testing
- Biospecimen Collection, Near Infrared Imaging, Pafolacianine Sodium
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Mayo Clinic
Postoperative Delirium (POD), Abdominal Neoplasms
Perioperative Biomarkers and Postoperative Delirium in Older Adults Undergoing Abdominal Cancer Surgery
This prospective observational cohort study aims to investigate the relationship between perioperative endogenous melatonin levels and postoperative delirium in patients aged 65 years or older undergoing elective abdominal cancer…
- Trial name
- NCT07859488
- Testing
- Perioperative Biomarker Assessment, Confusion Assessment Method (CAM)
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Fatma Cigdem Ozakin
Cervical Cancer
German-funded Laparoscopic Approach to Cervical Cancer
The G-LACC trial is a prospective, interventional, multicenter, open-label, randomized and controlled non-inferiority operative trial.
- Trial name
- G-LACC (NCT06489795)
- Testing
- Laparoscopic or robot-assisted radical/simple hysterectomy, Abdominal radical/simple hysterectomy
- Where
- 14 sites in Germany
- Volunteers
- 756 people
- Sponsor
- Hannover Medical School
Lung Cancer (Diagnosis), Liver Cancer, Adult
A Study Evaluating a New Radiation Treatment Workflow (NGDS)
The purpose of this research is to evaluate the "Next Generation Delivery System" (NGDS) and determine if this machine will be more efficient at delivering radiation in shorter treatment time and better patient tolerance, with…
- Conditions
- Lung Cancer (Diagnosis), Liver Cancer, Adult, Pancreatic Cancer, Thoracic Cancers
- Trial name
- SPEED (NCT07824583)
- Testing
- Next Generation Delivery System (NGDS)
- Where
- 2 sites in United States
- Volunteers
- 20 people
- Sponsor
- Varian, a Siemens Healthineers Company
Peritoneal Carcinomatosis, Oligometastatic Disease
MRI-Guided Adaptive Radiotherapy for Limited Peritoneal Metastases (MARACAS Trial).
This prospective phase II study evaluates the efficacy and safety of MRI-guided stereotactic body radiotherapy (MRIgSBRT) in patients with oligometastatic peritoneal carcinomatosis from gastrointestinal or gynecological tumors.
- Conditions
- Peritoneal Carcinomatosis, Oligometastatic Disease, Peritoneal Metastases
- Trial name
- MARACAS (NCT07593261)
- Testing
- MRI-guided stereotactic body radiotherapy
- Where
- Italy
- Volunteers
- 34 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Prehabilitation, Major Abdominal Surgeries
PROPOSAL FOR A PREOPERATIVE FUNCTIONAL OPTIMIZATION PATHWAY FOR PATIENTS CANDIDATE FOR MAJOR SURGERY (CARDIAC AND ABDOMINAL ONCOLOGY)
The study aims to evaluate a prehabilitation protocol for patients undergoing cardiac and abdominal surgery. The project for a preparation program for cardiac surgery was developed within the framework of ERAS (Enhanced Recovery…
- Conditions
- Prehabilitation, Major Abdominal Surgeries, Cardiac Surgery, Multimodal and Integrated Program
- Trial name
- PRIME CARE (NCT07851350)
- Where
- 2 sites in Italy
- Volunteers
- 50 people
- Sponsor
- ASST Sette Laghi
Stage I Testicular Seminoma, Stage I Testicular Nonseminomatous Germ Cell Tumor
Assessment of Compliance With Monitoring Conducted by a Physician in Person or by a Nurse in Remote Monitoring
This is a multicenter, interventional, randomized study among adult patients recently diagnosed with a rare tumor (<12 months). The study will aim to compare compliance with the personalized post-treatment surveillance plan…
- Conditions
- Stage I Testicular Seminoma, Stage I Testicular Nonseminomatous Germ Cell Tumor, Gastrointestinal Stromal Tumors, Ovarian Germ Cell Tumor
- Trial name
- SUR-CAN (NCT05500391)
- Testing
- Oncological Follow-up
- Where
- 3 sites in France
- Volunteers
- 88 people
- Sponsor
- Centre Oscar Lambret
Laparoscopy
Outcome of Resection for Colorectal Cancer
There are limited data from retrospective studies regarding whether short-term and long-term outcomes after laparoscopic or robot-assisted radical colectomy (minimally invasive surgery) are equivalent to those after open…
- Trial name
- LRLCC (NCT03837782)
- Testing
- minimally invasive surgery
- Where
- China
- Volunteers
- 1,300 people
- Sponsor
- Tianjin Medical University Cancer Institute and Hospital
Pancreatic Cancer, Jaundice
The LINFU® U.S. Registry in Patients With Clinical Signs and/or Symptoms of Disease
Evaluate LINFU® in patients who exhibit signs or symptoms (i.e. jaundice, abdominal pain, weight loss, nausea and vomiting etc.) suggestive of pancreatic cancer (PDAC) or have evidence of imaging studies suggestive of PDAC.
- Conditions
- Pancreatic Cancer, Jaundice, Abdominal Neoplasm
- Trial name
- NCT06276738
- Testing
- LINFU® (Low Intensity Non-Focused Ultrasound excitation of the pancreas)
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Adenocyte, LLC
Liver Resection, Liver Tumours
Evaluation Of Liver Resection Using Harmonic Scalpel Versus Cavitron Ultrasonic Surgical Aspirator (CUSA).
Evaluation Of Liver Resection Using Harmonic Scalpel Versus Cavitron Ultrasonic Surgical Aspirator (CUSA) Introduction The mode of parenchymal transection in hepatic resection has been a topic of great debate for decades.
- Conditions
- Liver Resection, Liver Tumours, Liver Transplant Disorder, Trauma Abdomen
- Trial name
- NCT07142876
- Testing
- Liver resection Cavitron Ultrasonic Surgical Aspirator (CUSA), Liver resection with the harmonic scalpel
- Volunteers
- 50 people
- Sponsor
- Sohag University
Ovarian Neoplasms, Peritoneal Neoplasms
Tolerance, Safety, Efficacy, and Pharmacokinetics of Pressurized Intraperitoneal Aerosol Chemotherapy (PIPAC) Using Paclitaxel for Platinum-resistant Recurrent Ovarian Cancer
The purpose of this study is to evaluate the tolerance, safety, efficacy, and pharmacokinetics of pressurized intraperitoneal aerosol chemotherapy (PIPAC) with paclitaxel in patients with platinum-resistant recurrent ovarian…
- Trial name
- NCT07273396
- Testing
- Pressurized intraperitoneal aerosol chemotherapy (PIPAC) using paclitaxel
- Volunteers
- 53 people
- Sponsor
- Seoul National University Hospital
Abdominal Sepsis
Characterization of Abdomino-pelvic Lesions by 18Fluorine- Fluorodeoxyglucose Positron Emission Tomography/Computed Tomography
The aim of the study is to identify and characterize lesions in the abdominopelvic region detected by 18fluorine- fluorodeoxyglucose (FDG) positron Emission Tomography combined Computed Tomography (PET/CT) scan, including…
- Trial name
- 18F-FDG PET/CT (NCT07127627)
- Testing
- PET/CT
- Volunteers
- 79 people
- Sponsor
- Assiut University
Abdominal Aortic Aneurysm, Primary Lung Cancer
Epidemiology of Abdominal Aortic Aneurysm With Concomitant Primary Lung Cancer
Retrospective clinical case studies in recent years have shown that most cases of lung cancer and abdominal aortic aneurysm (AAA) are detected at the same time and that there is a wide variation in the prevalence of AAA in…
- Conditions
- Abdominal Aortic Aneurysm, Primary Lung Cancer, Prevalence
- Trial name
- NCT06775821
- Testing
- Ultrasound or CT of the abdominal aorta
- Where
- 2 sites in China
- Volunteers
- 2,000 people
- Sponsor
- First Affiliated Hospital of Kunming Medical University
Upper Abdominal Malignancies
Liver Volume Variation Effect on SBRT Planning and Delivery for Upper Abdominal Malignancies
Standard planning constraints for liver SBRT incorporate strict dose-volume limits for normal liver parenchyma to minimize the risk of radiation-induced liver disease.
- Trial name
- NCT06355895
- Testing
- Standardized high-carbohydrate meal
- Where
- United States
- Volunteers
- 17 people
- Sponsor
- University of Pittsburgh
Peritoneal Carcinomatosis
Flat Dose vs. Weight-based IP Chemotherapy for CRS/HIPEC
Peritoneal carcinomatosis from advanced gastro-intestinal malignancy has historically been associated with poor overall survival (≤ 12 months) with few treatment options.
- Trial name
- NCT04779554
- Testing
- Mitomycin C, flat dose 40 mg, Mitomycin C, weight-based dose 12.5 mg/m2
- Where
- 2 sites in United States
- Volunteers
- 100 people
- Sponsor
- Prakash Pandalai
Abdominal Cancer, Pelvic Cancer
A Study to Determine Whether Perioperative Energy Dynamics Correlates With Postoperative Outcomes
To validate a new method for assessing perioperative risk in the cancer patient undergoing major cancer surgery. In this proposed study researchers will: 1. Measure preoperative energy reserve capacity (fitness) 2.
- Trial name
- NCT00493688
- Testing
- Cardiopulmonary Exercise Testing (CPET)
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- M.D. Anderson Cancer Center
Upper Abdominal Malignancies
Coeliac Plexus vs Splanchnic Nerve Neurolysis for Upper Abdominal Cancer Pain
The goal of this clinical trial is to determine whether Neurolytic Splanchnic Nerve Block (NSNB) reduces pain in adults with upper abdominal malignancies.
- Trial name
- NCT07653906
- Testing
- Neurolytic Coeliac Plexus Block (NCPB), Neurolytic Splanchnic Nerve Block (NSNB)
- Where
- Bangladesh
- Volunteers
- 44 people
- Sponsor
- Bangladesh Medical University
Abdomen Cancer, Pancreas Adenocarcinoma (MSI-H)
Implementation of a Pain Management Plan in Major Open Abdominal Surgeries.
Introduction: Major abdominal surgery encompasses a broad range of surgical procedures in heterogeneous patient populations.Management of postoperative pain has received keen attention in recent years with considerable concurrent…
- Conditions
- Abdomen Cancer, Pancreas Adenocarcinoma (MSI-H), Colectomy Left/Right/Total Under Laparotomy, Hepatectomy
- Trial name
- NCT07901582
- Testing
- Epidural administered opioid
- Where
- Greece
- Volunteers
- 58 people
- Sponsor
- National and Kapodistrian University of Athens