Clinical trials: Abdominal Site
Sarcoma, Soft Tissue, Retroperitoneal Neoplasms
Long Term Morbidity and Quality of Life in Retroperitoneal Sarcomas
No prospective data exist about long term morbidity and quality of life after multivisceral surgical resection for retroperitoneal soft tissue sarcoma (RSTS).
- Conditions
- Sarcoma, Soft Tissue, Retroperitoneal Neoplasms, Surgery, Quality of Life
- Trial name
- LTM (NCT03480399)
- Volunteers
- 60 people
- Sponsor
- Fondazione IRCCS Istituto Nazionale dei Tumori, Milano
Adenopathy, Uterine Fibroids
A Clinical Study on the Feasibility and Safety of Abdominal Endoscopic Single-port Surgery System to Assist Gynecological Day Surgery
In this study, a prospective study is used to select patients who will undergo intra-abdominal endoscopic single-port surgery system for benign gynecological diseases from February 2025 to December 2026 in the Second Affiliated…
- Conditions
- Adenopathy, Uterine Fibroids, Ovarian Cysts, Adnexal Mass
- Trial name
- NCT06828419
- Testing
- Domestic single-port laparoscopic surgery system
- Where
- China
- Volunteers
- 63 people
- Sponsor
- Second Affiliated Hospital of Wenzhou Medical University
Type 2 Diabetes
Ultrasound Effects on Glycemic Control in T2DM
This is an open label, exploratory pilot study that will assess the effects of dual site focused pulsed ultrasound treatment on glycemic parameters in subjects with T2DM.
- Trial name
- U/S_in_T2DM (NCT05354947)
- Testing
- Ultrasound Delivery
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Yale University
Head and Neck Cancer, Thoracic Cancer
Evaluation of On-Couch CBCT Image Quality
This is a prospective, single-arm, single-site study designed to generate data describing the image quality and applicability/useability of a high-performance, on-couch CBCT imaging technology (HyperSight) in patients receiving…
- Conditions
- Head and Neck Cancer, Thoracic Cancer, Abdominal Cancer, Pelvic Cancer
- Trial name
- NCT06576908
- Testing
- HyperSight Imaging
- Where
- Canada
- Volunteers
- 46 people
- Sponsor
- Varian, a Siemens Healthineers Company
Abdominal Cancer, Pelvic Cancer
Radiotherapy Treatments for Neoplasms in the Abdominal-pelvic Region
Evaluation of clinical and dosimetric aspects, tolerance, and effectiveness of abdominal-pelvic region radiotherapy treatments in patients undergoing radiotherapy for primary or secondary neoplasms localized in the…
- Trial name
- NCT06335238
- Where
- Italy
- Volunteers
- 7,700 people
- Sponsor
- European Institute of Oncology
Body Mass Index Greater Than or Equal to 30, Malignant Breast Neoplasm
Negative Pressure Wound Therapy in Healing Abdominal Incision in Obese Patients Undergoing Breast Reconstruction Surgery
This trial studies the safety and how well negative pressure wound therapy works in healing the abdominal incision in obese patients undergoing free flap breast reconstruction surgery.
- Conditions
- Body Mass Index Greater Than or Equal to 30, Malignant Breast Neoplasm, Mammoplasty Patient, Obesity
- Trial name
- NCT04003038
- Testing
- Negative Pressure Wound Therapy, Wound Care Management
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- M.D. Anderson Cancer Center
Gastric Cancer Stage IV, Peritoneal Carcinomatosis
Intraperitoneal Paclitaxel Plus Systemic mFOLFOX6
Treatment for stage 4 gastric cancer with peritoneal carcinomatosis has been unchanged for decades. The median survival for stage 4 gastric cancer is 9-14 months with systemic chemotherapy.
- Conditions
- Gastric Cancer Stage IV, Peritoneal Carcinomatosis, Intraperitoneal Paclitaxel, mFOLFOX6
- Trial name
- IPLUS (NCT03618758)
- Testing
- Paclitaxel, mFOLFOX6 regimen
- Where
- South Korea
- Volunteers
- 35 people
- Sponsor
- Seoul National University Bundang Hospital
Peritoneal Carcinomatosis
Preoperative Inflammatory Markers Predict Postoperative Complications After Cytoreductive Surgery and Hyperthermic Intraperitoneal Chemotherapy for Peritoneal Colorectal Carcinomatosis
A retrospective study of a single-center prospective database of patients who underwent curative CRS-HIPEC for peritoneal carcinomatosis (PC) of colo-rectal cancer (CRC), between September 2012 and July 2023 at Reims…
- Trial name
- NCT06318793
- Where
- France
- Volunteers
- 166 people
- Sponsor
- CHU de Reims
Surgical Site Infection
Protocol Effect of Negative Pressure Drain to Reducing Surgical Site Infection in Surgical Wound of Abdominal Surgery
Surgical site infection (SSI) is one of main complication in surgery. It usually occurs within 30 days post operation. The superficial SSI is an infection of skin and subcutaneous layer, clinically presented by pus oozing.
- Trial name
- NCT05865821
- Testing
- Negative pressure drainage, No pressure drain
- Where
- Thailand
- Volunteers
- 130 people
- Sponsor
- Mahidol University
Abdominal Tumor, Pelvic Tumor
Daily Adjustment of the Radiation Dose in MRI-guided Stereotactic Radiotherapy for Tumors in the Abdominal and Pelvic Regions
SBRT delivers high-dose radiation to precisely defined target volumes and is an effective locally ablative treatment option for both primary tumours and oligometastases in various settings, including lesions in the abdomen or…
- Trial name
- ACTION (NCT07687147)
- Testing
- SBRT with adaptive fractionation, Standard of Care (SOC)
- Where
- Switzerland
- Volunteers
- 100 people
- Sponsor
- University of Zurich
Ovarian Neoplasms, Fallopian Tube Neoplasms
Vandetanib to Treat Women With Ovarian, Fallopian Tube, or Primary Peritoneal Cancer
Background: Vandetanib is a drug that attacks a group of proteins on the surface of many cells, especially blood vessel cells and tumor cells. Tumors require the development of new blood vessels in order to grow and spread.
- Conditions
- Ovarian Neoplasms, Fallopian Tube Neoplasms, Peritoneal Neoplasms
- Trial name
- NCT00445549
- Testing
- Vandetanib
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- National Cancer Institute (NCI)
Non-small Cell Lung Cancer, Mesothelioma
Study of Pemetrexed in Mesothelioma and Lung Cancer Patients With Fluid Around the Lungs or Abdomen
This study will test the effects of pemetrexed on mesothelioma and non-small cell lung cancer patients with fluid around their lungs or abdomen.
- Conditions
- Non-small Cell Lung Cancer, Mesothelioma, Lung Neoplasms
- Trial name
- NCT00316225
- Testing
- pemetrexed
- Where
- 3 sites in Denmark, Germany and 1 more
- Volunteers
- 31 people
- Sponsor
- Eli Lilly and Company
Abdomen Hernia
The Effects of Post-Operative Interventions on Surgical Site Occurrences in AWR
Randomized controlled trial to compare SSO's in abdominal wall reconstruction patients using Prevena, Prineo, and traditional incisional dressings.
- Trial name
- NCT04906408
- Testing
- Prevena, Prineo, Traditional
- Where
- United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Ohio State University
Peritoneal Neoplasms
A Phase II Study of Surgical Debulking With Peritonectomy and Biweekly Intraperitoneal 5FU With Systemic Oxaliplatin/5FU/Leucovorin in Patients With Pseudomyxoma Peritonei or Peritoneal Carcinomatosis
This study prospectively evaluates a multidisciplinary approach to patients with intraperitoneal carcinomatosis at Washington University.
- Trial name
- NCT00352755
- Testing
- Surgical debulking with peritonectomy, Intraperitoneal 5FU, FOLFOX
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- Washington University School of Medicine
Malignant Peritoneal Neoplasm, Malignant Retroperitoneal Neoplasm
Nivolumab With or Without Ipilimumab in Treating Patients With Recurrent or High Grade Gynecologic Cancer With Metastatic Peritoneal Carcinomatosis
This phase Ib trial studies the side effects and best dose of nivolumab with or without ipilimumab in treating patients with female reproductive cancer that has come back (recurrent) or is high grade and has spread extensively…
- Conditions
- Malignant Peritoneal Neoplasm, Malignant Retroperitoneal Neoplasm, Metastatic Cervical Carcinoma, Metastatic Endometrial Carcinoma
- Trial name
- NCT03508570
- Testing
- Ipilimumab, Laboratory Biomarker Analysis, Nivolumab
- Where
- United States
- Volunteers
- 26 people
- Sponsor
- M.D. Anderson Cancer Center
Gastric Adenocarcinoma, Gastric Cancer
Intraperitoneal and Intravenous Paclitaxel Chemotherapy With Oral Capecitabine for Gastric Adenocarcinoma With Peritoneal Carcinomatosis
Background: Three-fourths of people diagnosed with gastric cancer will die from it. Researchers want to see if giving cancer drugs in a new way can help people live longer and delay the time it takes for the cancer to grow.
- Conditions
- Gastric Adenocarcinoma, Gastric Cancer, Esophagogastric Junction, Peritoneal Carcinomatosis
- Trial name
- NCT04034251
- Testing
- Paclitaxel, Capecitabine, BardPort Titanium Implanted Port with Peritoneal Catheter
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- National Cancer Institute (NCI)
Anemia
Pilot Study of Epoetin Alfa for Patients Having Abdominal or Pelvic Surgery for Cancer
This pilot study is looking at how well epoetin alfa, given in the immediate post-operative period, works in reducing anemia and the need for transfusions.
- Trial name
- NCT00294203
- Testing
- Epoetin Alfa group
- Where
- 2 sites in United States
- Volunteers
- 40 people
- Sponsor
- University of Florida
Obesity, Abdominal, Surgery
Perioperative Blood Adiponectin Dynamics and Systemic Infflamatory Response After Major Colorectal Surgery
Surgical stress after major abdominal surgery in perioperative period causes neuroendocrine, metabolic and imunologic changes in organism with production of proinfflamatory citokines and results with appearance of systemic…
- Conditions
- Obesity, Abdominal, Surgery, Systemic Inflammatory Response Syndrome, Postoperative Complications
- Trial name
- ADIPOS (NCT06057207)
- Testing
- serum levels of adiponectin, IL-6, Postoperative systemic infflamation
- Where
- 2 sites in Croatia
- Volunteers
- 58 people
- Sponsor
- Osijek University Hospital
Colorectal Cancer
Efficacy of HIPEC in Patients With Colorectal Cancer at High Risk of Peritoneal Carcinomatosis
The purpose of this study is to determine the efficacy of adjuvant HIPEC with Mitomycin C after colectomy in the treatment of colorectal cancer patients at high risk of peritoneal carcinomatosis.
- Trial name
- NCT04370925
- Testing
- Radical colectomy, HIPEC, Systemic chemotherapy
- Where
- 37 sites in China
- Volunteers
- 688 people
- Sponsor
- Affiliated Cancer Hospital & Institute of Guangzhou Medical University
Incisional Hernia
The Use of Different Types of Mesh for Prevention of Incisional Hernia Versus Primary Abdominal Suturing
The use of different types of mesh at different sites in prevention of incisional hernia after various abdominal incision versus primary abdominal suturing.
- Trial name
- NCT05359510
- Testing
- prophylactic mesh repair at different sites for prevention of incisional hernia after various abdominal incision versus primary abdominal suturing
- Where
- Egypt
- Volunteers
- 25 people
- Sponsor
- Assiut University