Clinical trials: Abdominal Site
Surgery--Complications, Pelvic Cancer
Reconstruction in Extended MArgin Cancer Surgery
Advanced pelvic cancers are uncommon, with treatment being challenging. Around 4000 patients every year need treatment in the UK. Cancers can involve multiple organs and often need radiotherapy and chemotherapy before surgery.
- Conditions
- Surgery--Complications, Pelvic Cancer, Abdominal Cancer, Quality of Life
- Trial name
- REMACS (NCT05219058)
- Testing
- Biological mesh reconstruction, Myocutaneous flap reconstruction, Primary closure reconstruction
- Where
- 18 sites in United Kingdom
- Volunteers
- 236 people
- Sponsor
- University Hospital Southampton NHS Foundation Trust
Laparotomy, Dehiscence Wound
Barbed Suture vs Non-Barbed Closure for Emergency Exploratory Laparotomy RCT
This randomized control trial aims to compare the efficacy of triclosan-coated barbed suture (TCB) versus conventional non-barbed polydioxanone (PDS) suture in the closure of the abdominal fascia after emergency exploratory…
- Conditions
- Laparotomy, Dehiscence Wound, Surgical Site Infections, Trauma Abdomen
- Trial name
- NCT06043414
- Testing
- triclosan-coated barbed suture, triclosan-coated non-barbed suture, Non-coated non-barbed suture
- Where
- United States
- Volunteers
- 250 people
- Sponsor
- University of Southern California
Colostomy, Colorectal Neoplasm
A Randomized Trial on the Technical Aspects of Stoma Construction.
An investigation on the difference in stoma hernia frequency related to surgical technique when incising the fascia. All patients planned for elective colostomy formation are to be included.
- Conditions
- Colostomy, Colorectal Neoplasm, Diverticulitis
- Trial name
- NCT01694238
- Testing
- Cruciate incision, Circular incision, Mesh enforced cruciate incision
- Where
- Sweden
- Volunteers
- 209 people
- Sponsor
- Sahlgrenska University Hospital
Intraabdominal Hypertension, Breast Neoplasms
DIEP Flap Surgery and Intraabdominal Pressure
Aim: The primary aim of this study is to test if closure of the abdominal donor site increases the Intraabdominal Pressure (IAP) in women undergoing secondary Deep Inferior epigastric perforator (DIEP) flap breast reconstruction.
- Trial name
- NCT05764577
- Testing
- DIEP flap surgery
- Where
- Denmark
- Volunteers
- 13 people
- Sponsor
- Aalborg University Hospital
Ovarian Cancer, Peritoneal Cavity Cancer
Intraperitoneal Paclitaxel Albumin-Stabilized Nanoparticle Formulation in Treating Patients With Advanced Cancer of the Peritoneal Cavity
RATIONALE: Drugs used in chemotherapy, such as paclitaxel albumin-stabilized nanoparticle formulation, work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing.
- Conditions
- Ovarian Cancer, Peritoneal Cavity Cancer, Unspecified Adult Solid Tumor, Protocol Specific
- Trial name
- NCT00825201
- Testing
- paclitaxel albumin-stabilized nanoparticle formulation, liquid chromatography, mass spectrometry
- Where
- 2 sites in United States
- Volunteers
- 27 people
- Sponsor
- City of Hope Medical Center
Hepatocellular Carcinoma, Transcatheter Arterial Chemoembolization
Effects of Esketamine on Acute Abdominal Pain After TACE in Patients With Hepatocellular Carcinoma
Pain is the main complication after TACE(Transcatheter Arterial Chemoembolization) for hepatocellular carcinoma, and its pathogenesis is not clear.The pain may be related to partial liver tissue swelling after blocking the tumor…
- Conditions
- Hepatocellular Carcinoma, Transcatheter Arterial Chemoembolization, Pain
- Trial name
- NCT05670561
- Testing
- Esketamine, Sufentanil
- Where
- China
- Volunteers
- 60 people
- Sponsor
- The Second Affiliated Hospital of Chongqing Medical University
Cancer of Pancreas, Ossification, Heterotopic
Heterotopic Ossification in Abdominal Incision and Pancreatic Cancer
To investigate whether pancreatic cancer is the cause of heterotopic ossification of abdominal incision.
- Trial name
- NCT04049461
- Testing
- Bone alkaline phosphatase, Abdominal CT scan
- Where
- China
- Volunteers
- 105 people
- Sponsor
- Nanjing Medical University
Inguinal Hernia
Prospective Randomized Trial Comparing Three-port and Single-port TEP Repair in Adults
Inguinal hernia is one of the most common surgical diseases. Over the past years, the safety and feasibility of laparoscopy was established and gaining popularity in recent few years.
- Trial name
- NCT01591395
- Testing
- laparoscopic total extraperitoneal hernia repair (single port vs. multiport)
- Where
- Taiwan
- Volunteers
- 100 people
- Sponsor
- Taipei Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation
Lymphatic Malformation, Lymphangioma
Clinical Characteristics of Lymphatic Malformations
The primary purpose of this study is to retrospectively identify the clinical characteristics of abdominal lymphatic malformations (ALMs) in our single center in China.
- Trial name
- NCT06257719
- Testing
- Compare the epidemiological characteristics, clinical presentations, surgical treatments and risk factors for preoperative complications of ALMs between paediatric and adult participants.
- Where
- China
- Volunteers
- 320 people
- Sponsor
- West China Hospital
Ovarian Neoplasms, Peritoneal Neoplasms
BIBF 1120 + Carboplatin/Pegylated Liposomal Doxorubicin (PLD) in Patients With Advanced Ovarian Cancer, Fallopian Tube Carcinoma or Primary Peritoneal Cancer
This phase I, open label dose escalation study will investigate the addition of BIBF 1120 to treatment with the combination of carboplatin and Pegylated Liposomal Doxorubicin (PLD) in patients with advanced, platinum sensitive…
- Trial name
- NCT01314105
- Testing
- BIBF 1120 + PLD 30 mg/m2 + CBDCA AUC5 mg/mL*min, BIBF 1120+ PLD 30 mg/m2 + CBDCA AUC5 mg/mL*min
- Where
- 3 sites in Spain
- Volunteers
- 19 people
- Sponsor
- Boehringer Ingelheim
Cryptogenic Pyogenic Liver Abscess
Prevalence of Colon Cancer in Pyogenic Liver Abscess
Although a proportion of pyogenic liver abscess may originated from colonic mucosal lesions, the prevalence of colonic neoplasm in the patients with pyogenic liver abscess are still not evaluated yet.
- Trial name
- NCT02032914
- Where
- 2 sites in South Korea
- Volunteers
- 62 people
- Sponsor
- Inje University
Hepatocellular Carcinoma
Combination of SBRT, PD-L1 Inhibitor, and Lenvatinib in Hepatocellular Carcinoma (HSBRT2401)
Abdominal lymph node metastasis (LNM) is one of the major modes of extrahepatic metastasis in hepatocellular carcinoma (HCC). Immunotherapy targeting the PD-1/PD-L1 checkpoints combined with targeted therapy is the standard…
- Trial name
- HSBRT2401 (NCT06261125)
- Testing
- Stereotactic body radiotherapy, Adebrelimab, Lenvatinib
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Mian XI
Gastric Cancer, Lung Cancer
Evaluation of Respiratory Motion-Corrected Cone-Beam CT in Radiation Treatment of Thoracic and Abdominal Cancers
Tumors must be seen clearly on CT scan to be radiated completely and safely. Breathing causes tumors to move. If the tumor moves during breathing, it can look blurred on the CT scan. This makes it difficult to see on CT scan.
- Trial name
- NCT01213004
- Testing
- respiration correlated CT scan
- Where
- United States
- Volunteers
- 52 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
Surgical Site Infection, Cesarean Section; Infection
Abdominal Closure Bundle to Reduce Surgical Site Infection in Patients Undergoing C-sections. Cesarean Section Lead to Reduction in Surgical Site Infection? - A Randomized Controlled Trial
This study is a single center, randomized controlled trial investigating the use of an abdominal closure bundle to reduce surgical site infection in patients undergoing cesarean section.
- Trial name
- NCT03500055
- Testing
- Abdominal Closure Bundle
- Where
- United States
- Volunteers
- 850 people
- Sponsor
- Abington Memorial Hospital
Fallopian Tube Cancer, Ovarian Cancer
Laparoscopic Staging in Patients With Ovarian, Fallopian Tube, or Other Primary Abdominal Cancers
RATIONALE: Laparoscopic staging may help doctors plan more effective treatment for ovarian, primary fallopian tube, and primary abdominal cancers.
- Conditions
- Fallopian Tube Cancer, Ovarian Cancer, Primary Peritoneal Cavity Cancer
- Trial name
- NCT00002538
- Testing
- laparoscopic surgery
- Where
- 11 sites in United States
- Sponsor
- Gynecologic Oncology Group
Indirect Inguinal Hernia, Undescended Testis
INVESTIGATION OF THE GENETIC ETIOLOGY OF HERNIA SAC DEVELOPMENT IN MALE CHILDREN WITH UNDESCENDED TESTIS AND INGUINAL HERNIA
The aim of the project is to elucidate the genetic etiology underlying the development of the processus vaginalis (PV) in male children with indirect inguinal hernia (IIH) and undescended testis (UT), through the investigation of…
- Trial name
- NCT07586332
- Where
- Turkey (Türkiye)
- Volunteers
- 3 people, healthy volunteers welcome
- Sponsor
- Trakya University
Cervical Cancer, Postoperative Pain
Laparoscopic vs Abdominal Radical Hysterectomy In Patients With Early Cervical Cancer
The purpose of this study is to determine whether laparoscopic radical hysterectomy for early cervical cancer will has decreased postoperative pain intensity compared to abdominal radical hysterectomy with similar postoperative…
- Trial name
- NCT01258413
- Testing
- Laparoscopic Radical Hysterectomy + pelvic lymphadenectomy, Abdominal radical hysterectomy
- Where
- Brazil
- Volunteers
- 30 people
- Sponsor
- Hospital Nossa Senhora da Conceicao
Large Bowel Cancer
Effects of Different Strategy of Fluids Administration on Acid/Base Disorders and Inflammatory Mediators
Aim of the study is to ascertain whether a different strategy of fluids administration can be responsible of differences in terms of acid/base disorders (Stewart approach), pro-inflammatory and inflammatory mediators.
- Trial name
- NCT01320891
- Testing
- balanced solutions, not balanced
- Where
- Italy
- Volunteers
- 40 people
- Sponsor
- Università degli Studi di Ferrara
Peritoneal Surface Malignancies
The Intraoperative Physiologic Changes of Patients Under Hyperthermic Intraperitoneal Chemotherapy (HIPEC) Cytoreductive Surgery; Prospective Observational Study
The most popular surgical treatment of peritoneal cancer is the type known as hyperthermic intraperitoneal chemoperfusion (HIPEC), a type of cytoreductive surgery for which a significantly high survival rate has been demonstrated…
- Trial name
- NCT02325648
- Testing
- HIPEC cytoreductive surgery
- Where
- South Korea
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Yonsei University
Overweight and Obesity, Men
High-Intensity Interval Training and Fat Mass Losses
The aims of this study was to compare two isoenergetic HIIT (High-intensity Interval training) programs (cycling vs. running) on body composition, substrate oxidation at rest and during a moderate exercise, muscle functionality…
- Trial name
- RIESLING (NCT05311800)
- Testing
- Physical activity
- Where
- France
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- Laboratoire des Adaptations Métaboliques à l'Exercice en conditions Physiologiques et Pathologiques