Clinical trials: Abdominal Surgery
Quality of Recovery
A Study to Investigate Quality of Recovery up to Day 7 in Females Undergoing Laparoscopic Abdominal Surgery Provided Apfel-score Based PONV Care and Prophylaxis
SYNOPSIS Title: An observational study to investigate Quality of Recovery and the incidence and impact of Post-Operative Nausea and Vomiting (PONV)/Post-Discharge Nausea and Vomiting (PDNV) and up to 7 days in females undergoing…
- Trial name
- NCT03820479
- Testing
- Protocol
- Where
- Sweden
- Volunteers
- 98 people
- Sponsor
- Danderyd Hospital
Laparotomy
Effect of TAP Block on Ventilatory Function Following Abdominal Surgery
Abdominal surgery impairs ventilation. Postoperative pain accounts for this impairment. Regional analgesia is known to reduce pain, thus to limit ventilatory impairment.
- Trial name
- KTAP (NCT01719796)
- Testing
- Regional analgesia infusion
- Where
- 2 sites in France
- Volunteers
- 60 people
- Sponsor
- Pierre and Marie Curie University
Peritoneal Carcinomatosis, Colon Cancer
Metachonous Peritoneal Carcinomatosis Incidence After Curative Surgery for pT4 Colon Cancer Patients
This is an observational retrospective cohort study to determine metachronous peritoneal carcinomatosis in a specific subgroup of colon cancer patients, those with a final pathologic exam corresponding to pT4 tumors.
- Trial name
- NCT05300789
- Testing
- Follow-up
- Where
- Spain
- Volunteers
- 1,152 people
- Sponsor
- Carlos Cerdán Santacruz
Hernia, Ventral Hernia
Prospective Clinical Evaluation of High-Purity Type I Collagen in Select High-Risk Hernia Repair Scenarios
This prospective, single-arm clinical study evaluates the safety, feasibility, and early clinical outcomes of High-Purity Type I Collagen (HPTC; Surgicoll-Mesh®) when used as a biologic reinforcement in selected hernia repair…
- Conditions
- Hernia, Ventral Hernia, Incisional Hernia, İnguinal Hernia
- Trial name
- NCT07360691
- Testing
- High-Purity Type I Collagen Mesh
- Where
- India
- Volunteers
- 30 people
- Sponsor
- Adichunchanagiri Institute of Medical Sciences, B G Nagara
Inguinal Hernia
Biomechanically Compatible,Minimally Invasive Technique for Recurrence Free Groin Hernia Repair
"A bio-mechanically compatible, minimally invasive technique for recurrence-free groin hernia repair by implantation of Tensiflex mesh prosthesis for the enhancement of the tissue tensile strength of the fascia transversalis."
- Trial name
- NCT04764760
- Testing
- Wing shaped Tensiflex prosthesis
- Where
- United States
- Volunteers
- 486 people, healthy volunteers welcome
- Sponsor
- St. Joseph Mercy Oakland Hospital
Postoperative Pain, Surgery
Exparel Use in Bilateral TAP Blocks for Postoperative Pain Control
To determine if Exparel (Liposomal Bupivacaine, an FDA approved drug) use in ultrasound guided Transversus Abdominis Plane (TAP) blocks may reduce opioid requirement use postoperatively, reduce pain scores postoperatively, reduce…
- Conditions
- Postoperative Pain, Surgery, Anesthesia, Local
- Trial name
- NCT03878888
- Testing
- Exparel 266 MG Per 20 ML Injection
- Where
- United States
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- St. Luke's Hospital, Pennsylvania
Fraily, Abdominal Surgery
Awareness Neuraxial Versus General Anesthesia in Frail Patients Undergoing Laparoscopic or Robotic Abdominopelvic Surgery.
This is a bicentric, prospective, non-pharmacological, randomized study designed to compare the efficacy and safety of awake neuraxial anesthesia with sedation versus general anesthesia in frail patients undergoing elective major…
- Conditions
- Fraily, Abdominal Surgery, Postoperative Cognitive Dysfunction (POCD)
- Trial name
- SAFE-AWARENESS (NCT07486336)
- Testing
- Neuraxial anesthesia, General Anesthesia, avoidance of GABAergic-drugs strategy
- Where
- 2 sites in Italy
- Volunteers
- 100 people
- Sponsor
- Ente Ospedaliero Ospedali Galliera
Abdominal Tumor, Intestinal Obstruction
Comparison the Hemodynamics Effects Between Dexmedetomidine and Propofol in Major Abdominal Surgical Patients
The alpha2 agonist dexmedetomidine is a new sedative agent combined with the analgesic qualities and lack of respiratory depression.
- Conditions
- Abdominal Tumor, Intestinal Obstruction, Cirrhosis, Intestinal Fistula
- Trial name
- NCT01669044
- Testing
- dexmedetomidine, propofol
- Where
- China
- Volunteers
- 80 people
- Sponsor
- First Affiliated Hospital, Sun Yat-Sen University
Emergency Abdominal Surgery, Colorectal Surgery
Effect of Malignancy on Morbidity and Mortality in Left-sided Emergency Colorectal Resections
Patients who underwent emergency left sided colorectal resection in a single center between January 2023 and May 2024 were included.
- Conditions
- Emergency Abdominal Surgery, Colorectal Surgery, Acute Diverticulitis, Volvulus
- Trial name
- NCT06958900
- Where
- Turkey (Türkiye)
- Volunteers
- 76 people
- Sponsor
- Kanuni Sultan Suleyman Training and Research Hospital
Pain, Acute
Bilateral Ultrasound-Guided Intra Muscular Quadratus Lumborum Block Versus Trans Muscular Quadratus Lumborum Block for Peri-Operative Analgesia in Abdominal Surgeries in Pediatric Patients. A Comparative Controlled Randomized Study.
To compare between the intra muscular quadratous lamborum and the Trans muscular quadratous lamborum in pediatric population under going abdominal surgeries regards to first request of rescue analgesia, degree of pain relief…
- Trial name
- NCT04029987
- Testing
- Bilateral Ultrasound-Guided Transmuscular Quadratus Lumborum Block., Bilateral Ultrasound-Guided intra smuscular Quadratus Lumborum Block., Control
- Where
- Egypt
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Kasr El Aini Hospital
Pelvic Organ Prolapse, Abdominal Surgery
The Effect of Abdominal Binder Use on Postoperative Pain and Mobility in Patients Undergoing Pelvic Surgery
To determine the effect of post-operative abdominal binder usage on total narcotic usage after undergoing surgery. To determine if abdominal binder usage results in decreased visual analog scale (VAS) pain scores and shorter time…
- Conditions
- Pelvic Organ Prolapse, Abdominal Surgery, Laparoscopic Surgery, Post Operative Pain
- Trial name
- NCT03684304
- Testing
- Abdominal binder
- Where
- United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- University Hospitals Cleveland Medical Center
Ileus Postoperative, Postoperative Nausea and Vomiting
Postoperative Gastric Point of Care Ultrasound (G-POCUS) in Abdominal Surgery
The purpose of this research is to determine if gastric point of care ultrasound (G-POCUS) can be used to help clinicians determine when to feed patients or when to insert or remove nasogastric tubes for patients recovering from…
- Trial name
- NCT05796063
- Testing
- gastric point of care ultrasound
- Where
- United States
- Volunteers
- 128 people, healthy volunteers welcome
- Sponsor
- Thomas Jefferson University
Laparoscopy, Discharge Planning
Post-discharge Monitoring Initiative on Outcomes of Post-surgical Patients
The investigators are conducting a prospective study to evaluate the SKH@Home programme, a post-discharge monitoring initiative for surgical patients.
- Trial name
- SKH@home (NCT06980402)
- Testing
- Early post-surgical discharge with post-surgical home based monitoring, Standard inpatient care until deemed suitable for discharge
- Volunteers
- 1,000 people
- Sponsor
- Sengkang General Hospital
Acute Appendicitis, Perforated Gastroduodenal Ulcer
Antibiotic Prophylaxis in the Prevention of Surgical Site Infections After Selected Urgent Abdominal Surgical Procedures
Aim of prospective randomized a placebo controlled study is to prove that in case of acute surgical procedure due to appendicitis, ileus of small bowel and perforation of small bowel and stomach appropriately administered…
- Conditions
- Acute Appendicitis, Perforated Gastroduodenal Ulcer, Small Bowel Obstruction
- Trial name
- NCT01524081
- Testing
- Metronidazole, Cefuroxime, Amoxicillin (+ clavulanic acid) and Fluconazole
- Where
- Czechia
- Volunteers
- 187 people
- Sponsor
- The Faculty Hospital Na Bulovce
Intracranial Pressure Increase, Abdominal Pain
Different Intraperitoneal Pressures on Optic Nerve Sheath Diameter in Laparoscopic Surgeries
The aim of this study is to investigate the effects of low and normal intraperitoneal pressures on intraoperative optic nerve sheath diameter in laparoscopic gyneco-oncologic surgeries.
- Conditions
- Intracranial Pressure Increase, Abdominal Pain, Head Pain
- Trial name
- NCT07155109
- Testing
- Low pressure group, Normal pressure group
- Where
- Turkey (Türkiye)
- Volunteers
- 99 people, healthy volunteers welcome
- Sponsor
- Diskapi Yildirim Beyazit Education and Research Hospital
Abdominal Aortic Aneurysm, Morbid Obesity
Pilot Study on the Effectiveness and Safety of OPTILENE® SILVER MESH ELASTIC in Prevention of Surgical Site Infection (SSI) and Incisional Hernia (IH)
The aim of the study is to describe the effectiveness of Optilene® Silver Mesh Elastic on prevention of surgical site infection (SSI) at 6 months follow-up in patients undergoing urgent laparotomy by collecting clinical data on…
- Trial name
- SSIHLVER (NCT06547138)
- Testing
- Prophylactic mesh
- Where
- 5 sites in Spain
- Volunteers
- 110 people
- Sponsor
- Aesculap AG
Abdominal Aortic Aneurysm Without Rupture, Abdominal Aortic Aneurysm, Ruptured
Prospective Aortic Biobank of POP-STAR
The overall objective of the POP-STAR project is individualized surveillance for patients diagnosed with abdominal aortic aneurysms by means of more precise, patient-specific AAA growth prediction.
- Conditions
- Abdominal Aortic Aneurysm Without Rupture, Abdominal Aortic Aneurysm, Ruptured, Aortic Aneurysm, Aneurysm Abdominal
- Trial name
- NCT04269447
- Testing
- Structured imaging follow-up
- Where
- 2 sites in Sweden
- Volunteers
- 400 people
- Sponsor
- Karolinska University Hospital
Postoperative Complications
Intraoperative Fluid Management Guided by Internal Jugular Vein on Postoperative Complications in Abdominal Surgeries
This study investigates the role of respiratory variation in the internal jugular vein as a tool for intraoperative fluid management during abdominal surgeries under general anesthesia.
- Trial name
- NCT07041021
- Testing
- Respiratory variation of the Internal Jugular Vein (IJV)
- Where
- 2 sites in Egypt
- Volunteers
- 84 people
- Sponsor
- Suez Canal University
Renal Insufficiency, Chronic, Acute Pain
Efficacy Transverse Abdominal Plane (TAP) Block Renal Transplant Surgery
The objective of this study is to evaluate the efficacy and safety of transverse abdominal plane block in patients undergoing renal transplant surgery.Adult renal transplant recipients will be prospectively randomized to receive…
- Conditions
- Renal Insufficiency, Chronic, Acute Pain, Kidney Transplantation, Anesthesia, Conduction
- Trial name
- NCT03181438
- Testing
- TAP Block, Saline Group
- Where
- Brazil
- Volunteers
- 42 people
- Sponsor
- Federal University of São Paulo
Chronic Postoperative Pain
Effect of Intraoperative Dexmedetomidine on Postoperative Pain in Elderly Patients Undergoing Major Abdominal Surgery: a Secondary Analysis Based on Prospective Data
This study is a secondary analysis of multicenter prospective data, including elderly patients who underwent elective major abdominal surgery between April 2020 and April 2022 from a perioperative database of elderly patients in…
- Trial name
- NCT07744308
- Where
- China
- Volunteers
- 2,754 people
- Sponsor
- Chinese PLA General Hospital