Clinical trials: Abdominal Wall Defect
Abdominal Wall Defect, Abdominal Wall Infection
The Use of Synthetic Mesh in Contaminated and Infected Abdominal Wall Repairs. A Long-term Prospective Clinical Trial
Background: Abdominal wall reconstruction in patients presenting with enteric fistulas and mesh infection is challenging. There is a consensus that synthetic mesh must be avoided in infected operations.
- Conditions
- Abdominal Wall Defect, Abdominal Wall Infection, Abdominal Wall Fistula, Infection
- Trial name
- NCT03702153
- Testing
- Abdominal wall reconstruction
- Where
- Brazil
- Volunteers
- 80 people
- Sponsor
- University of Sao Paulo General Hospital
Quality of Life, Abdominal Wall Defect
Health Related Quality of Life of Patients With Abdominal Wall Defects
Examination of the health-related quality of life of patients operated on due to congenital defects of the abdominal wall after birth with the questionnaires KINDL, SDQ and SF-36.
- Conditions
- Quality of Life, Abdominal Wall Defect, Gastroschisis, Omphalocele
- Trial name
- NCT03960320
- Testing
- questionnaire
- Volunteers
- 65 people
- Sponsor
- Universität des Saarlandes
Ventral Hernia, Abdominal Wall Defect
Intraoperative Biomechanics in Complex Abdominal Wall Reconstruction
Background: A detailed study of the biomechanical changes before and after abdominal wall reconstruction (AWR) has not been performed.
- Trial name
- NCT03296475
- Testing
- Abdominal Wall Closure Force (N).
- Where
- United Kingdom
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University College, London
Abdominal Wall Defect
Evaluation of the Motor Activity, Cardiopulmonary Performance Capacity and Quality of Life in Patients Born With a Congenital Abdominal Wall Defect
The two most common congenital abdominal wall defects (AWD) are gastroschisis and omphalocele. Prenatal detection is often possible and the defects are differentiated by the presence or absence of a sac around the eviscerated…
- Trial name
- NCT04644965
- Testing
- CombynTM Function & Spaces ECG, Blood Taking, Spiroergometry
- Where
- Austria
- Volunteers
- 20 people
- Sponsor
- Medical University of Graz
Hernia Repair With Compartment Syndrome
Feasibility Study of The Use of FLEX HD® Surgical Implant or STRATTICE® Reconstructive Tissue Matrix in The Closure of Abdominal Wall Defects With Component Separation in Clean or Contaminated Cases
This study examines the feasibility of using Flex HD® Surgical Implant or STRATTICE® Reconstructive Tissue Matrixin the repair of hernias.
- Trial name
- Flex HD (NCT01597128)
- Testing
- Flex HD, Strattice
- Where
- United States
- Volunteers
- 35 people
- Sponsor
- John Roth
Abdominal Hernia, Abdominal Wall Defect
To Investigate the Use of a New Syringe "Visual Pressure Control (VPC)" for Epidural Anesthesia in Children Surgery
Pediatric epidural anesthesia has emerged as a safe and effective regional anesthesia technique for providing intraoperative and postoperative analgesia in thoracic and abdominal surgery.
- Conditions
- Abdominal Hernia, Abdominal Wall Defect, Abdominal Neoplasm, Urogenital Disease
- Trial name
- NCT05308771
- Testing
- VPC syringe
- Where
- Belgium
- Volunteers
- 15 people
- Sponsor
- Centre Hospitalier Universitaire de Tivoli
Abdominal Wall Defect, Abdominal Wall Hernia
The Efficacy and Security of the Small Stitch Technique in Emergency Surgery
This study evaluates the abdominal closure technique in emergency surgery. Half of participants will be perform the classic Large Stitch technique, while the other half will undergo the Small Stitch technique.
- Conditions
- Abdominal Wall Defect, Abdominal Wall Hernia, Eventration, Evisceration; Operation Wound
- Trial name
- STCU (NCT03765060)
- Testing
- Monomax® 2/0 HR26, Monomax® 1 HR48
- Where
- Spain
- Volunteers
- 105 people
- Sponsor
- Fundación Pública Andaluza para la gestión de la Investigación en Sevilla
Ventral Hernia, Abdominal Wall Defect
ExtrAperitoneaL Plasty vs Intraperitoneal oNlay mEsh in Ventral Hernia Repair
This study investigates on the effect of two different operative techniques to treat abdominal wall hernias. The goal of this clinical trial is to learn if the eTEP (Extended totally extraperitoneal repair) technique leads to a…
- Trial name
- ALPINE (NCT06367309)
- Testing
- Extended totally extraperitoneal repair, Intraperitoneal onlay mesh
- Where
- Switzerland
- Volunteers
- 138 people
- Sponsor
- University Hospital, Basel, Switzerland
Abdominal Wall Defects
A Retrospective Study Evaluating the Use of Permacol Surgical Implant in the Repair of Abdominal Wall Defects
To evaluate short, mid and long term clinical outcomes associated with the use of Permacol in the treatment of abdominal wall defects.
- Trial name
- NCT01214252
- Testing
- Permacol Surgical Implant
- Where
- United States
- Volunteers
- 343 people
- Sponsor
- Medtronic - MITG
Ventral Hernia
The Use of Biologic Mesh vs Bioabsorbable Mesh During Ventral Hernia Repair in At-risk Patients
This study evaluates the outcomes of patients who have been treated with Strattice or Gore Bio-A mesh for the repair of complicated abdominal wall hernias.
- Trial name
- NCT01794338
- Testing
- Strattice Arm, Bio-A Arm
- Where
- United States
- Volunteers
- 28 people
- Sponsor
- Wake Forest University Health Sciences
Gastroschisis, Intestinal Occlusion
Prospective Study of Antenatal Diagnostic Criteria for Digestive Complications of Gastroschisis
Gastroschisis is a rare congenital malformation consisting in a right para-umbilical defect of the abdominal wall leading to an evisceration of the abdominal content.
- Trial name
- LaparoDAN (NCT04174807)
- Where
- 36 sites in France, Martinique
- Volunteers
- 200 people
- Sponsor
- University Hospital, Angers
Abdominal Wall Defect, Hemorrhage
Tranexamic Acid in Abdominoplasty.
The investigators prepared a novel tranexamic acid (TXA) study designed to estimate the quantity of blood loss in patients undergoing abdominoplasty surgery.
- Conditions
- Abdominal Wall Defect, Hemorrhage, Bleeding
- Trial name
- NCT06086444
- Testing
- Tranexamic acid
- Where
- Poland
- Volunteers
- 60 people
- Sponsor
- Poznan University of Medical Sciences
TAR Technique
Evaluation of TAR Technique in the Treatment of Huge Abdominal Wall Hernia and Large Abdominal Wall Defect With or Without Botox Injection .
Aim of the work In this study, we will evaluate posterior component separation (TAR) technique with or without Botox injection for open huge ventral hernia and large abdominal wall defect repair.
- Trial name
- NCT04419844
- Testing
- Tar with Botox
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Mansoura University
Abdominal Wall Defect, Ventral Hernia
Clinical Study on the Safety of SAFIL® MESH
Observational, Retrospective, Multi-center Clinical Study on the Safety of SAFIL® MESH in Patients Undergoing Reinforcement of Soft Tissues After Abdominal Wall Surgery or Other Fascial Defects
- Conditions
- Abdominal Wall Defect, Ventral Hernia, Abdominal Hernia, Fascial Hernia
- Trial name
- SAFIL_MESH (NCT04947202)
- Testing
- Hernioplasty
- Where
- 2 sites in Spain
- Volunteers
- 152 people
- Sponsor
- Aesculap AG
Diastasis Recti and Weakness of the Linea Alba, Abdominal Wall Defect
Patient-Reported Outcomes in Women With Postpartum Abdominal Wall Insufficiency (PPAWIS)
Postpartum abdominal wall insufficiency syndrome (PPAWIS) is a multidimensional condition that may affect physical function, quality of life, body image, and sexual health in women after childbirth.
- Conditions
- Diastasis Recti and Weakness of the Linea Alba, Abdominal Wall Defect, Postpartum Complication, Abdominal Wall Anomaly
- Trial name
- EMPOWER (NCT07407374)
- Testing
- Routine Clinical Care
- Volunteers
- 30 people
- Sponsor
- Swissmed Hospital
Recurrent Hernia
Review of Complex Recurrent Hernia Repair
Abdominal wall incisional hernia is a common finding in patients who have undergone previous intra-abdominal surgeries. Common methods of abdominal fascial closure include primary closure, mesh inlay versus onlay, with or without…
- Trial name
- BARS (NCT01644695)
- Testing
- Bony Anchoring Reinforcement System
- Where
- United States
- Volunteers
- 85 people
- Sponsor
- Institute For Advanced Reconstruction
Hernia, Surgical Wound Dehiscence
Repair of Challenging Abdominal Wall Defects: Strattice(TM) TM in Abdominal Wall Repair (StAR)
The objective of this study is to compare the incidence of post-repair wound related complications, including hernia occurrence/recurrence, between challenging abdominal wall defects repaired with Strattice(TM) Reconstructive…
- Trial name
- StAR (NCT01083472)
- Testing
- Strattice(TM) Reconstructive Tissue Matrix, Suture/suture with absorbable mesh
- Where
- 29 sites in France, Germany and 4 more
- Volunteers
- 37 people
- Sponsor
- LifeCell
Navel; Hernia
A Common But Unknown Disease; Nave Sliding (NS)
The present study is a case series study, conducted to introduce a common disease of abdominal wall which has received less attention in scientific resources.
- Trial name
- NS (NCT04998929)
- Testing
- complementary therapy
- Where
- Iraq
- Volunteers
- 20 people
- Sponsor
- Komar University of Science and Technology
Abdominal Wall Defect
A Prospective Multicentre Study Evaluating the Outcomes of the Abdominal Wall Dehiscence Repair Using Posterior Component Separation With Transversus Abdominis Muscle Release Reinforced by a Retro-muscular Mesh - Filling a Step
Purpose: This study determined the incidence of burst abdomen recurrent (BAR), incisional hernia(IH), and surgical site occurrence (SSO) following burst abdomen surgical treatment after abdominal midline incisions using a…
- Trial name
- NCT05278117
- Testing
- outcomes of complete burst abdomen repair using posterior component separation technique with transversus abdominis muscle release reinforced by sublay mesh
- Where
- Egypt
- Volunteers
- 202 people
- Sponsor
- Zagazig University
Ventral Hernia, Incisional Hernia
oPen Versus RobotIc retrOmuscular Repair in Medium to Large Ventral Hernias
This study investigates on the effect of two different operative techniques to treat large abdominal wall defects. The goal of this clinical trial is to learn if the minimally-invasive, robotically-assisted ventral hernia repair…
- Conditions
- Ventral Hernia, Incisional Hernia, Abdominal Wall Defect
- Trial name
- PRIOR (NCT06364306)
- Testing
- Robotically-assisted ventral hernia repair (RVHR), Open ventral hernia repair (OVHR)
- Where
- 3 sites in Germany, Switzerland
- Volunteers
- 140 people
- Sponsor
- University Hospital, Basel, Switzerland