Clinical trials: Abdominal Wall Hernia
Congenital Diaphragmatic Hernia
Microbiome and Volatile Organic Compounds in Patients With CDH
Despite improved prenatal diagnostics and therapeutic possibilities, congenital diaphragmatic hernia (CDH) represents a cross-disciplinary challenge.
- Trial name
- CDHVOCS (NCT03787160)
- Testing
- initial VOC, initial fecal microbiome, initial pulmonary microbiome
- Where
- Austria
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Medical University of Graz
Congenital Diaphragmatic Hernia
Fetoscopic Endoluminal Tracheal Occlusion (FETO) for Severe Left Diaphragmatic Hernia (CDH)
Despite advances in prenatal diagnosis and postnatal therapies, including extracorporeal membrane oxygenation (ECMO), inhaled nitric oxide therapy, and ventilator strategies that minimize ventilator-induced lung injury, morbidity…
- Trial name
- FETO (NCT02710968)
- Testing
- 11540KE and Balt Goldbal 2 balloon
- Where
- United States
- Volunteers
- 21 people
- Sponsor
- Johns Hopkins University
Hernia, Inguinal, Hernia
3D HD Versus 2D HD in Laparoscopic Inguinal Hernia Repair: a Randomized Controlled Trial
The aim of this study is to compare 3D-laparoscopy versus 2D-laparoscopy with the use of HD resolution in inguinal hernia repair in terms of error rating, performance time and subjective assessment.
- Trial name
- NCT02396940
- Testing
- 3D HD laparoscopy, 2D HD laparoscopy
- Where
- Denmark
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Herlev Hospital
Congenital Diaphragmatic Hernia, Pulmonary Hypertension
Efficacy of Inhaled Nitric Oxide in Congenital Diaphragmatic Hernia
This multicenter, prospective, single-arm study aims to evaluate the efficacy of inhaled nitric oxide (iNO) in neonates with congenital diaphragmatic hernia (CDH) and early pulmonary hypertension.
- Trial name
- INOCDH (NCT07247240)
- Testing
- Inhaled Nitric Oxide
- Where
- 4 sites in South Korea
- Volunteers
- 40 people
- Sponsor
- Asan Medical Center
Hernia, Inguinal, Recurrence
Hernia Belt in Laparoscopic Inguinal Hernia Repair
In this study, the investigators aimed to investigate the effect of hernia belt on postoperative complications and quality of life for patients who underwent laparoscopic inguinal hernia repair.
- Conditions
- Hernia, Inguinal, Recurrence, Seroma Following Procedure, Pain, Postoperative
- Trial name
- NCT06061068
- Testing
- Hernia belt compression
- Where
- China
- Volunteers
- 678 people
- Sponsor
- Nanchong Central Hospital
Paraesophageal Hernia
Posterior Rectus Sheath Hiatal Augmentation in Paraesophageal Hernia Repair
This study will be a prospective observation study of the use of PoRSHA for repair in patients with challenging paraesophageal hernias.
- Trial name
- NCT06551077
- Testing
- POSTERIOR RECTUS SHEATH HIATAL AUGMENTATION (PORSHA)
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- University of Chicago
Ventral Hernia
Prolonged Hospital Stay and Readmission After Elective Ventral Hernia Repair
The aim of the present study was to analyse factors associated with prolonged length of hospital stay, readmission and death in a nationwide group of patients undergoing elective ventral hernia repair in search for areas of…
- Trial name
- LOSHERNIA (NCT01388634)
- Where
- Denmark
- Volunteers
- 2,258 people
- Sponsor
- Zealand University Hospital
Hernia Inguinal, Biologic Mesh
Effect of Biologic vs Synthetic Mesh on Chronic Pain After Laparoscopic Repair of Contralateral Asymptomatic Hernia in Patients With Unilateral Symptomatic Inguinal Hernia
Inguinal hernia is one of the most common conditions in general surgery. In clinical practice, surgeons frequently face a dilemma: during the evaluation of a patient with unilateral symptomatic inguinal hernia, a contralateral…
- Trial name
- BiSAH (NCT07649434)
- Testing
- Biologic Mesh, Synthetic Mesh
- Where
- China
- Volunteers
- 90 people
- Sponsor
- Xiangya Hospital of Central South University
Hernia, Ventral, Hernia, Abdominal
Abdominal Wall Tension in Patients Undergoing Ventral Hernia Repair Without Component Separation
The purpose of this study is to use a scale to learn more about the tension of the abdominal wall in hernia repairs without component separation. 1.
- Conditions
- Hernia, Ventral, Hernia, Abdominal, Hernia Abdominal Wall
- Trial name
- NCT06051578
- Testing
- Abdominal wall tension measurement
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- The Cleveland Clinic
Ventral Hernia, Postoperative Pain
Full-thickness Skin vs. Synthetic Mesh in the Repair of Large Incisional Hernia
This is a prospective randomized study to compare surgical methods for the repair of large abdominal hernia.
- Trial name
- NCT01413412
- Testing
- Ventral hernia repair using full thickness skin graft, Ventral hernia repair using mesh
- Where
- Sweden
- Volunteers
- 50 people
- Sponsor
- Karolinska Institutet
Inguinal Hernia
Effects of Morphine Added to Bupivacaine in Transversus Abdominis Plane Block for Inguinal Hernia Repair
This study is conducted to determine whether morphine added to bupivacaine in ultrasound guided (USG) transversus abdominis plane (TAP) block has beneficial effects than bupivacaine alone in providing postoperative analgesia for…
- Trial name
- NCT05379374
- Testing
- bupivacaine and morphine
- Where
- Nepal
- Volunteers
- 40 people
- Sponsor
- B.P. Koirala Institute of Health Sciences
Congenital Diaphragmatic Hernias
Contribution of PRF in CDH in Children With Prothetic Patch Closure
Improved management of giant congenital diaphragmatic hernias (CDH) in neonates : decreased risk of morbidity and mortality due to prosthesis release.
- Trial name
- HECODIAP (NCT03861182)
- Testing
- Biological functionalization of the prosthetic materials by PRF
- Where
- France
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University Hospital, Strasbourg, France
Inguinal Hernia, Ventral Hernia
Post-operative Pain Control-TAP Block Using Exparel vs. Marcaine for Hernia Repairs
While studies have shown improved postoperative pain control with TAP blocks after inguinal and ventral hernia repair, data comparing Liposomal bupivacaine (Exparel) to bupivacaine alone in formulation of the TAP block is…
- Trial name
- NCT05177991
- Testing
- Liposomal Bupivacaine, Bupivacaine
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- Leslie Son
Inguinal Hernia, Constipation
Relationship Between Constipation and Inguinal Hernia
The purpose of this study is to asses the effect of chronic constipation on formation of inguinal hernia using Constipation Severity Scale.
- Trial name
- NCT02749682
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Siverek Devlet Hastanesi
Ventral Hernia
Miromatrix Biological Mesh for Ventral Hernia Repair
This study is being conducted to gather long-term data of the performance of the Miromatrix Biological Mesh.
- Trial name
- MIROMESH PM-1 (NCT02408458)
- Testing
- MIROMESH®
- Where
- 4 sites in United States
- Sponsor
- Miromatrix Medical Inc.
Ventral Hernia, Incisional Hernia
A Prospective, Multicenter All Comers Study of Phasix Mesh for Ventral or Incisional Hernia Repair
Collect data on safety, performance, and effectiveness of Phasix Mesh in subject requiring primary ventral and incisional hernias.
- Trial name
- NCT02053168
- Testing
- Resorbable Mesh
- Where
- 6 sites in United States
- Volunteers
- 33 people
- Sponsor
- C. R. Bard
Inguinal Hernia, Convalescence
Pain and Convalescence After Laparoscopic Groin Hernia Repair
The investigators want to identify limiting factors for short convalescence after laparoscopic groin hernia repair. Before the operation patients are given intensive structured information about one day´s convalescence.
- Trial name
- Lap-Lyske (NCT00962338)
- Testing
- Information
- Where
- Denmark
- Volunteers
- 210 people
- Sponsor
- Zealand University Hospital
Incisional Hernia, Ventral Hernia
Watchful Waiting of Incisional Hernias
This study is being conducted to gain a better understanding of the quality of life for patients with a diagnosis of primary and recurrent incisional hernias and 1) who decline to have surgery to repair the hernia or 2) patients…
- Conditions
- Incisional Hernia, Ventral Hernia, Umbilical Hernia
- Trial name
- NCT00351455
- Testing
- smoking cessation, tighter diabetic control, diet and exercise program
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Baylor College of Medicine
Abdominal Wound Dehiscence, Burst Abdomen
Vacuum-Assisted Closure Versus Graduated Primary Skin Closure for Postoperative Burst Abdomen
Burst abdomen, or complete abdominal wound dehiscence, is a severe postoperative complication characterized by the separation of the musculo-aponeurotic layer of the abdominal wall.
- Conditions
- Abdominal Wound Dehiscence, Burst Abdomen, Surgical Wound Dehiscence
- Trial name
- NCT07797868
- Testing
- Vacuum-Assisted Closure (VAC) Therapy, Graduated Primary Skin Closure
- Volunteers
- 50 people
- Sponsor
- Assiut University
Inguinal and Ventral Hernia Repair by Sublay, Underlay and IPOM Mesh Fixation
Effectiveness, Appropriateness and Safety of GLUTACK-Glubran Tiss 2 Surgical Glue Compared to GLUTACK-Glubran 2 Device System for Mesh Fastening in Laparoscopic and Robotic Hernia Surgery
This pre-market, prospective, randomized, non-inferiority clinical study was designed to evaluate the safety and performance/effectiveness of Glutack-Glubran® Tiss 2 system compared to Glutack-Glubran® used for mesh fixation in…
- Trial name
- AGluTHeMFix (NCT06462066)
- Testing
- Experimental medical device, Comparator medical device
- Where
- Italy
- Volunteers
- 101 people
- Sponsor
- GEM SRL
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