Clinical trials: Ablation Techniques
Atrial Fibrillation
The Physiological Effects of Pacing on Catheter Ablation Procedures to Treat Atrial Fibrillation
This is a two arm randomized, paired prospective study comparing the percentage of time spent above Contact Force (CF), Force Time Integral (FTI) and other lesion parameters in the setting of pacing versus non-pacing.
- Trial name
- PEP AF (NCT02766712)
- Testing
- Pace During 1st Half of Lesion, Pace During 2nd Half of Lesion
- Where
- United States
- Volunteers
- 64 people
- Sponsor
- NYU Langone Health
Lung Tumor, Metastatic Cancer
A Novel Method for Treating Lung Met w/Combo of Electric Fields & Rad Therapy: A Single-Arm
This is a phase 0, pilot prospective study to determine the feasibility of combined irreversible electroporation (IRE) and radiation therapy in subjects with lung tumors with metastatic cancer of any histology.
- Trial name
- NCT05555342
- Testing
- Irreversible electroporation (IRE) ablation, Radiation Therapy
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- University of California, Irvine
Paroxysmal Atrial Fibrillation, Persistent Atrial Fibrillation
ULTRA-HFIB-Redo: Ultrasound-based Renal Sympathetic Denervation vs Control in Redo Ablation Patients
This is a Prospective, controlled, single-blind, randomized (2:1, Intervention:Control) clinical trial. The purpose of the study is to determine the role of adjunctive renal sympathetic denervation in the prevention of Atrial…
- Trial name
- NCT05988411
- Testing
- Renal Denervation, Catheter Ablation
- Where
- 8 sites in United States
- Volunteers
- 143 people
- Sponsor
- Vivek Reddy
Menorrhagia
A Study to Compare the Effectiveness of Two Different Outpatient Endometrial Ablation Techniques Used for Heavy Periods
STUDY HYPOTHESIS: Does outpatient NovaSureTM endometrial ablation alleviate excessive menstrual bleeding and improve life quality more effectively than outpatient ThermachoiceTM endometrial ablation?
- Trial name
- COAT (NCT01124357)
- Testing
- NovaSure, thermachoice
- Volunteers
- 81 people
- Sponsor
- Birmingham Women's NHS Foundation Trust
Atrial Fibrillation (AF)
Augmented Reality Aided Remote Access and Technical Support for Complex Ablation Procedures
Prospective, randomized, controlled, single-center pilot study evaluating the feasibility and safety of augmented reality-based remote technical support using the Microsoft HoloLens and EnSite™ Connected Care compared with…
- Trial name
- HOLO-Remote (NCT07777042)
- Testing
- HoloLens supported catheter ablation, On-site supported catheter ablation
- Where
- Germany
- Volunteers
- 60 people
- Sponsor
- University of Luebeck
Back Pain Lower Back Chronic
Syringe Pressure Analysis: A Critical Examination of the Operator's Burden
This was a randomized prospective clinical trial conducted from October 1, 2023, to May 15, 2024, at the University Surgery Center in Merced, CA.
- Trial name
- NCT06476353
- Testing
- Analysis of Force and Pressure Requirements across Syringe Sizes for Pain Management Procedures
- Where
- United States
- Volunteers
- 224 people
- Sponsor
- Orthospine Advance Health, Inc.
Radiology, Interventional, Liver Neoplasm
Biliary or Digestive Protection by Room Air Interposition for Thermal Ablation of Central Hepatic Tumors
This study aims to analyse retrospectively the feasibility, the safety, and the efficiency, of biliary or digestive protection with room air interposition for thermal ablation of central liver tumors with high iatrogenic risk.
- Conditions
- Radiology, Interventional, Liver Neoplasm, Carcinoma, Hepatocellular (RENI), Neoplasm Metastasis
- Trial name
- NCT05495529
- Testing
- Thermal Ablation
- Where
- France
- Volunteers
- 61 people
- Sponsor
- Centre Hospitalier Universitaire de Nice
Cardiac Arrhythmias
Prospective Registry on User Experience With The Mapping System For Ablation Procedures
This is an observational, prospective, non-randomized, multicenter, post approval study being conducted in the United States, Europe and Asia-Pacific Regions.
- Trial name
- TRUE-HD (NCT02698670)
- Testing
- Rhythmia mapping system, IntellaMap Orion mapping catheter
- Where
- 28 sites in United States, Australia and 6 more
- Volunteers
- 577 people
- Sponsor
- Boston Scientific Corporation
Hepatocellular Carcinoma, Metastatic Liver Cancer
Safety and Effectiveness of BioTraceIO 360 for Planning, Monitoring and Assessment of Liver Tissue Ablation Procedures
Pilot study planned to demonstrate the safety and effectiveness of the use of BioTraceIO 360 for Planning, Monitoring and Assessment of liver tissue ablation procedures Multi-center (up to 5 investigational sites) prospective…
- Trial name
- PANORAMA (NCT05582018)
- Testing
- BioTraceIO 360
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- Techsomed Medical Technologies LTD
Atrial Fibrillation, Catheter Ablation
Esophageal Damage Protection During Pulmonary Vein Ablation. Pilot Study.
Catheter ablation of atrial fibrillation with electrical isolation of the pulmonary veins in the left atrium carries risk of esophagus thermal lesion. EnsoETM is a device .
- Conditions
- Atrial Fibrillation, Catheter Ablation, Esophageal Fistula, Esophageal Diseases
- Trial name
- NCT03832959
- Testing
- EnsoETM
- Where
- Spain
- Volunteers
- 60 people
- Sponsor
- Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau
Perianal Fistula
Comparing Three Surgical Techniques for the Treatment of Transsphincteric Perianal Fistula: (1) Traditional Fistulotomy (Lay Open), (2) Ligation of the Intersphincteric Tract (LIFT) With Adjunctive Endo Fistula Laser Ablation, and (3) Open LIFT Procedure Followed by LASER
>This randomized clinical trial compares three different surgical techniques for the treatment of transsphincteric perianal fistula: (1) traditional fistulotomy (lay open), (2) ligation of the intersphincteric tract (LIFT) with…
- Trial name
- NCT07236047
- Testing
- fistula lay open, LIFT plus LASER, open LIFT plus LASER
- Volunteers
- 90 people
- Sponsor
- Alexandria University
Keratomileusis, Laser In Situ
Mechanical vs. Alcohol Separation of the Corneal Epithelium During Surface Ablation Refractive Procedures
A recent survey of trends among the members of the American Society of Cataract and Refractive Surgery determined that laser in situ keratomileusis (LASIK) is the leading surgical procedure for photorefractive corrections ranging…
- Trial name
- NCT00366808
- Testing
- LASIK surgery
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Medical University of South Carolina
Atrial Fibrillation (Paroxysmal)
TWOSOME Trial: Single-Shot Versus Single-Tip Pulsed Field Ablation for Pulmonary Vein Isolation
Two non-thermal ablation techniques approved for routine clinical practice (CE-marked) for the interventional treatment of atrial fibrillation are compared in a 1:1 randomization to investigate patient data, procedural data…
- Trial name
- NCT07175727
- Testing
- Pulmonary vein isolation, cerebral magnetic resonance tomography, Biomarker assessment (C-reacitve Protein, troponine)
- Where
- Germany
- Volunteers
- 100 people
- Sponsor
- Alfried Krupp Krankenhaus
Carcinoma, Hepatocellular
RFA for Small HCC With No-touch Technique Using Octopus Electrode
In this study, the investigators are going to prospectively compare the clinical outcomes (technical success rate, 12 month local tumor progression rate, complication rate, tumor seeding rate) of Radiofrequency ablation (RFA)…
- Trial name
- NCT02832882
- Testing
- No-touch RFA, Conventional tumor puncture RFA
- Volunteers
- 118 people
- Sponsor
- Seoul National University Hospital
GERD (Gastroesophageal Reflux Disease), Throat Disorders
Comparing Two Different Methods of Ablation of Inlet Patches (APC vs RFA)
The goal of this prospective study is to compare 2 different treatment options for the ablation of inlet patches in patients with esophageal symptoms.
- Trial name
- NCT07252180
- Testing
- Argon plasma coagulation (APC), RFA
- Where
- Israel
- Volunteers
- 72 people
- Sponsor
- Assaf-Harofeh Medical Center
Barrett's Esophagus, Esophageal Cancer
TREAT-BE Study (Treatment With Resection and Endoscopic Ablation Techniques for Barrett's Esophagus)
A prospective outcomes study in patients with and esophageal cancer (EAC) and Barrett's esophagus (BE) associated neoplasia being evaluated for endoscopic eradication therapy (EET).
- Trial name
- NCT02634645
- Testing
- Endoscopic eradication therapies (EET), Esophagectomy, Chemotherapy
- Where
- 4 sites in United States
- Volunteers
- 5,000 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Persistent Atrial Fibrillation, Catheter Ablation
Left Atrial Function Analysis for Patients With Persistent Atrial Fibrillation Undergoing Pulmonary Vein Isolation
This prospective observational study is designed to describe the factors determining the success of pulmonary vein isolation (PVI) for patients with persistent atrial fibrillation (AF).
- Trial name
- LAMPP (NCT03242694)
- Testing
- LA pressure, voltage map, strain, scar-map, blood sampling, pulmonary vein isolation
- Where
- Hungary
- Volunteers
- 100 people
- Sponsor
- Semmelweis University Heart and Vascular Center
Ventricular Premature Complexes, Catheter Ablation
MANual vs. automatIC Local Activation Time Annotation for Guiding Premature Ventricular Complex Ablation
Current navigation systems incorporate algorithms for automatic identification of local activation time (LAT). However, data about their utility and accuracy in premature ventricular complex (PVC) ablation procedures are scarce.
- Trial name
- MANIaC-PVC (NCT03340922)
- Testing
- Automatic annotation of LAT (WF-method), Manual annotation of LAT (M-method)
- Where
- Spain
- Volunteers
- 100 people
- Sponsor
- Centro Medico Teknon