Clinical trials: Abnormal Cytology
Cervical Neoplasia
Feasibility of Delphi Screener for Cervical Cytology
The aim of this study is to see whether a new self-sampling device, the Delphi Screener (Delphi Devices, Scherpenzeel, Netherlands), can be used for cervical cancer screening.
- Trial name
- NCT00702208
- Testing
- Delphi Screener
- Where
- United States
- Volunteers
- 198 people, healthy volunteers welcome
- Sponsor
- Columbia University
Cervical Cancer Screening, HIV Infections
Anal HPV Infection and Abnormal Cytology in HIV-infected Women
The population of HIV infected women seen at Boston Medical Center may have a higher frequency of anal cytologic and histologic abnormalities than what is reported for the non-HIV infected population.
- Trial name
- NCT00933140
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Boston Medical Center
Human Papilloma Virus
Prevalence of Anal High-risk Human Papilloma Virus Infection and Abnormal Anal Cytology in Men Who Have Sex With Men Using Pre Exposure Prophylaxis
The aim of the study is to determine the prevalence of anal high-risk HPV infection and abnormal cytology in HIV uninfected Men who have sex with men (MSM) using PrEP and HIV infected MSM followed-up at the S-kliniek or HRC of…
- Trial name
- NCT04950101
- Testing
- anal sampling
- Where
- Belgium
- Volunteers
- 304 people, healthy volunteers welcome
- Sponsor
- Universitair Ziekenhuis Brussel
Papilloma-induced Cervical Lesions
Epigallocatechin Gallate and Other Antural Compounds in HPV Infections
The investigators enroll patients with a PAP-test cytology reporting LSIL or ASCUS. Pateitns undergo HPV-DNA test for screening.
- Trial name
- EGCGHPV (NCT06098456)
- Testing
- EGCG, FA, HA, B12
- Where
- Italy
- Volunteers
- 178 people
- Sponsor
- Centro di Ricerca Clinica Salentino
Breast Cancer
Phase 2 Study of Lovastatin as Breast Cancer Chemoprevention
The study evaluates if a 6-month course of oral lovastatin at 80 mg/day would decrease abnormal breast duct cytology in women with a high inherited breast cancer risk.
- Trial name
- NCT00285857
- Testing
- Lovastatin
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Stanford University
Diagnoses Disease, Screening
Strategies for Endocervical Canal Investigation in Women With Abnormal Screening Cytology and Negative Colposcopy
cervical cancer is the fourth most frequent cancer in women worldwide and in Brazil, it occupies the third position for the triennium 2020/2022, with a high mortality rate and maintained in the last 10 years.
- Conditions
- Diagnoses Disease, Screening, HSIL of Cervix, Cervical Cancer
- Trial name
- NCT05120167
- Testing
- Endocervical liquid-base cytology, Endocervical cell block, Endocervical curettage
- Where
- 4 sites in Brazil
- Volunteers
- 288 people, healthy volunteers welcome
- Sponsor
- Cirbia Silva Campos Teixeira
Abnormal Cytology
Oncogenous HPV DNA Integration (Intégration De l'ADN Des HPV Oncogènes)
High-risk human papillomavirus (HR-HPV) are involved in cervical cancer development. Integration of HR-HPV DNA in cellular genomes is considered as a major event in the cervical cancer development.
- Trial name
- IDAHO (NCT02864121)
- Testing
- all patients included in IDAHO study
- Where
- France
- Volunteers
- 407 people
- Sponsor
- CHU de Reims
High-risk HPV (Any Strain), LSIL, Low Grade Squamous Intraepithelial Lesion
Phase II Study of Dysplasix™ Intravaginal Suppositories in Patients Patients With High-Risk HPV and Mild Cervical Cytologic Abnormalities
The goal of this clinical trial is to learn if an investigational vaginal suppository therapy works to treat low-grade cervical lesions (ASC-US and LSIL) associated with high-risk human papillomavirus (hr-HPV) infection in women.
- Conditions
- High-risk HPV (Any Strain), LSIL, Low Grade Squamous Intraepithelial Lesion, ASC-US, HPV Infection
- Trial name
- NCT07572396
- Testing
- EGCG and Quinine Sulfate Vaginal Suppository
- Where
- Hong Kong
- Volunteers
- 45 people
- Sponsor
- Amplexd Therapeutics, Inc.