Clinical trials: Abnormal Hematopoiesis
Myelodysplastic Syndrome
Effects of Antithymocyte Globulin in Adults With Myelodysplastic Syndrome
Myelodysplastic syndrome (MDS) is a rare, potentially serious bone marrow disease. Currently available treatments for MDS have been only somewhat beneficial.
- Trial name
- NCT00466843
- Testing
- Antithymocyte globulin (ATG), Prednisone
- Where
- 4 sites in United States
- Volunteers
- 54 people
- Sponsor
- Office of Rare Diseases (ORD)
Abnormal Hematopoiesis, Allogenic Disease
Graft-versus-host Disease Associated Myelosuppression
The objective is to measure the frequency, functionality and phenotype of bone marrow-derived mesenchymal stromal cells in patients after allogeneic hematopoietic stem cell transplantation.
- Conditions
- Abnormal Hematopoiesis, Allogenic Disease, Graft vs Host Disease
- Trial name
- NCT02829216
- Where
- Germany
- Volunteers
- 50 people
- Sponsor
- Technische Universität Dresden
Myelodysplastic Syndrome, Acute Myeloid Leukemia
Epigenetics, Vitamin C and Abnormal Hematopoiesis - Pilot Study
This study evaluates whether vitamin C improves responses to epigenetic therapy with DNMTis. Half of the patients will receive vitamin C and DNMTi while the other half will receive placebo and DNMTi.
- Trial name
- EVITA-Pilot (NCT02877277)
- Testing
- Vitamin C
- Where
- Denmark
- Volunteers
- 20 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Myelodysplastic Syndromes, Chronic Myelomonocytic Leukemia-1
Epigenetics, Vitamin C, and Abnormal Blood Cell Formation - Vitamin C in Patients With Low-Risk Myeloid Malignancies
The primary purpose of this multi-centre, randomized, placebo-controlled, double-blind phase II study is to investigate if oral vitamin C may change the biology of low-risk myeloid malignancies; i.e., clonal cytopenia of…
- Conditions
- Myelodysplastic Syndromes, Chronic Myelomonocytic Leukemia-1, Cytopenia
- Trial name
- EVITA (NCT03682029)
- Testing
- Vitamin C (ascorbic acid)
- Where
- 5 sites in United States, Denmark
- Volunteers
- 109 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet