Clinical trials: Abortion, Complete
Abortion, Complete, Fetal Death
IntraCERvical Balloon Catheter in the Setting of Induction of Labor for Fetal Loss or Abortion
The goal of this research is to understand whether it is practical and safe to use an intracervical balloon catheter in addition to standard of care medications at the time of an induction of labor for an abortion or fetal death.
- Conditions
- Abortion, Complete, Fetal Death, Induction of Labor Affected Fetus / Newborn
- Trial name
- CERBI (NCT06456164)
- Testing
- Cook Cervical Ripening Balloon
- Sponsor
- University of Chicago
Legally Induced Abortion, Complete, Without Mention of Complication
R U OK? The Acceptability and Feasibility of New Communication Technologies for Follow-up After Medical Abortion
Purpose: This randomised trial will compare outcomes and acceptability of an alternative medical abortion follow-up protocol using standardised text messaging, on-line questionnaire, or a phone interview and a low sensitivity…
- Trial name
- NCT01362387
- Testing
- Alternative follow-up protocol
- Where
- 4 sites in United Kingdom
- Volunteers
- 999 people, healthy volunteers welcome
- Sponsor
- Gynuity Health Projects
Completion of Medical Abortion
Use of Low Sensitivity Pregnancy Test for Self-assessment of Medical Abortion
The purpose of the study is to design a self-assessment package that could be the preferred option to a follow-up visit at the clinic by the majority of women having early medical abortion.
- Trial name
- m-Assist+ (NCT02231619)
- Testing
- Baseline verbal instruction on LSUPT
- Where
- South Africa
- Volunteers
- 525 people
- Sponsor
- University of Cape Town
Medical Abortion, Complete or Unspecified, Without Complication
Second Trimester Medical Abortion
The use of Mifepristone, an antiprogesterone, and Misoprostol together, has been shown to make the medial abortion process more efficient and reduce the induction-to-abortion interval by almost 50%.
- Trial name
- RAPM (NCT04160221)
- Testing
- 12 hours interval, 24 hours interval
- Where
- Israel
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Sheba Medical Center
Complete Abortion
Mifepristone and Misoprostol for the Termination of Pregnancy up to 70 Days' Gestation in Kazakhstan
The study will be conducted in 4 sites and will examine how a simplified outpatient medical abortion procedure using mifepristone and misoprostol, with the option to take mifepristone at a place of woman's choosing, works in…
- Trial name
- NCT02018796
- Testing
- Mifepristone, misoprostol
- Where
- 4 sites in Kazakhstan
- Volunteers
- 290 people, healthy volunteers welcome
- Sponsor
- Gynuity Health Projects
Complete Uterine Evacuation After Use of Study Drugs
Medical Abortion With Mifepristone + Misoprostol (13 - 22 Weeks)
A double-blind randomized controlled trial to compare a shorter interval between the administration of mifepristone and misoprostol (simultaneous administration compared to 24hours from administration of mifepristone to receipt…
- Trial name
- NCT01768299
- Testing
- Mifepristone, Misoprostol
- Where
- 3 sites in Vietnam
- Volunteers
- 504 people, healthy volunteers welcome
- Sponsor
- Gynuity Health Projects
Complete Miscarriage
Use of Letrozole Pretreatment With Misoprostol for First-Trimester Medical Abortion
The purpose of this study is to compare the success rate of letrozole and misoprostol versus misoprostol alone for medical termination of first trimester pregnancy.
- Trial name
- NCT02401425
- Testing
- Letrozole, Misoprostol
- Where
- Egypt
- Volunteers
- 423 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Complete Abortion
Comparing Two Regimens for Medical Abortion: Mifepristone + Misoprostol Versus Misoprostol Alone
This double blinded, placebo-controlled randomized trial will compare the safety, efficacy and acceptability of two medical abortion regimens up to 63 days since last Menstrual Period (LMP) in Tunisia and Vietnam.
- Trial name
- NCT01387256
- Testing
- medical abortion
- Where
- 2 sites in Tunisia, Vietnam
- Volunteers
- 441 people, healthy volunteers welcome
- Sponsor
- Gynuity Health Projects
Medical; Abortion, Fetus
Comparison of Rate of Complete Abortion Between Letrozole Plus Misoprostol vs Misoprostol Alone
Comparison of rate of complete abortion between Letrozole plus Misoprostol versus Misoprostol alone in first trimester pregnancy
- Trial name
- NCT05940233
- Testing
- Letrozole
- Where
- Thailand
- Volunteers
- 70 people
- Sponsor
- Queen Savang Vadhana Memorial Hospital, Thailand
Pregnancy, Abortion Early
Assessment of Early Pregnancy MAB Completion
This is a prospective study to evaluate if successful completion of a medication abortion in patients with very early pregnancy can be detected with a urine pregnancy test at 2 weeks instead of 4 weeks.
- Trial name
- NCT06893484
- Testing
- Weekly high-sensitivity urine pregnancy tests
- Where
- 3 sites in United States
- Volunteers
- 400 people
- Sponsor
- University of Washington
Abortion Early, Abortion, Complete
Clotting Parameters After Medical Abortion
Venous thromboembolism (VTE - blood clots that form in deep veins or in the lungs) has been identified as a leading cause of death in economically developed countries for pregnant and recently-pregnant women.
- Conditions
- Abortion Early, Abortion, Complete, Abortion, Second Trimester, Termination of Pregnancy Complicated by Embolism
- Trial name
- C-PLAN (NCT04824118)
- Testing
- Thromboelastometry, Clotting Studies, Full Blood Count
- Where
- United Kingdom
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- NHS Lothian
Medical Abortion, Complete or Unspecified, Without Complication
Piloting Use of Multi-Level Pregnancy Tests in Remote Abortion Services
Serial use of urine multi-level pregnancy tests (MLPTs) has been shown to be a reliable and efficient strategy for excluding ongoing pregnancy after medical abortion at ≤ 63 days of gestation.
- Trial name
- NCT03207880
- Testing
- Multi-level pregnancy test
- Where
- United States
- Volunteers
- 165 people, healthy volunteers welcome
- Sponsor
- Gynuity Health Projects
Abortion, Complete, Miscarriage Threatening
Pregnancy Dating Test - The Fall of hPL in Urine Over Time
Earlier studies describe the half-life of hPL in serum as being ninety minutes and that the hormone is excreted unchanged in urine; consequently, there is real potential to use the fall in hormone levels in urine to monitor…
- Trial name
- NCT04217200
- Where
- United Kingdom
- Volunteers
- 11 people
- Sponsor
- Guy's and St Thomas' NHS Foundation Trust
Complete Abortion
Study on Combined Use of Letrozole, Mifepristone and Misoprostol in Termination of Pregnancy
By using the combination of mifepristone (anti-progestin), misoprostol (progstanglandin which stimulates uterine contraction), and letrozole (aromatise inhibitor which reduces estrogen production), the abortion process will be…
- Trial name
- NCT01475318
- Testing
- mifepristone, Letrozole, Misoprostol
- Where
- Hong Kong
- Volunteers
- 50 people
- Sponsor
- The University of Hong Kong
Induced Abortion
Study of the Sensitivity of Manual vs Electric Aspiration to Detect Completed Early Abortion
With sensitive urine pregnancy tests, women are now able to confirm very early pregnancies. However, approximately one third of abortion facilities do not offer abortions at less than six weeks of pregnancy.
- Trial name
- NCT01085825
- Testing
- D & C abortion
- Where
- United States
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Planned Parenthood of Greater New York
Medical Abortion, Complete or Unspecified, Without Complication
Randomized Study of Letrozole and Trilostane for Medical Abortion
In menstruation an effective shedding of the endometrial lining occurs. Both progesterone and estrogen levels fall sharply at this time.
- Trial name
- NCT01615211
- Testing
- Letrozole, Trilostane
- Where
- Sweden
- Volunteers
- 36 people
- Sponsor
- Kristina Gemzell Danielsson
Medical Abortion
Routine Follow-up Versus Self-assessment in Medical Abortion
The main objective of the study is to optimize the routines for follow-up after medical abortion in order to give women more autonomy by reducing the number of consultations involved and to reduce the frequency of postabortal…
- Trial name
- NCT01487213
- Testing
- Home self assessment of complete medical abortion
- Where
- 4 sites in Austria, Finland and 2 more
- Volunteers
- 929 people
- Sponsor
- Karolinska Institutet
Abortion
Mifepristone Versus Laminaria Insertion for Cervical Preparation Prior to Surgical Abortion at 14-16 Weeks
Women who are requesting pregnancy termination at 14-16 weeks, who would normally have osmotic dilator insertion the day before their procedure, would be asked if they wanted to participate.
- Trial name
- SAMi (NCT00986921)
- Testing
- mifepristone 200 mg, osmotic dilator insertion
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Boston University