Clinical trials: Abortion, Medical
Medical Abortion, Fetus
Reducing the Need for In-Clinic Follow-Up for Medical Abortion in Moldova and Uzbekistan
The purpose of this study is to determine whether an alternative method of follow-up after medical abortion is acceptable and feasible for use in Moldova and Uzbekistan.
- Trial name
- NCT01410266
- Testing
- Alternative follow-up
- Where
- 7 sites in Moldova, Uzbekistan
- Volunteers
- 2,400 people, healthy volunteers welcome
- Sponsor
- Gynuity Health Projects
Induced Abortion, Second Trimester Abortion
Midlevel Versus Physician-provided Medical Abortion in the Second Trimester
The purpose of the study is to determine the safety and effectiveness of second trimester medical abortion when provided by nurse midwives compared with physicians.
- Conditions
- Induced Abortion, Second Trimester Abortion, Medical Abortion, Health Personnel
- Trial name
- NCT04181541
- Testing
- Provider type: Physicians, Provider type: Midlevel Providers
- Where
- Ethiopia
- Volunteers
- 245 people, healthy volunteers welcome
- Sponsor
- Ipas
Medical Abortion
The Extended Gestational Age Medical Abortion Study
This open-label, comparative study will compare the efficacy, safety, and acceptability of 200 mg mifepristone followed in 24-48 hours by 800mcg buccal misoprostol or 400mcg sublingual misoprostol for termination of pregnancy in…
- Trial name
- NCT00997347
- Testing
- Mifepristone and misoprostol
- Where
- 12 sites in United States, Georgia and 3 more
- Volunteers
- 1,400 people, healthy volunteers welcome
- Sponsor
- Gynuity Health Projects
Induced Abortion
The Feasibility of Simplified Telephone Follow-up After Medical Abortion
To assess the feasibility of using simplified telephone follow-up to predict pregnancy expulsion after medical abortion, and if in-person follow-up is required to determine the percentage of women that will present for that…
- Trial name
- SMART (NCT00619658)
- Testing
- telephone follow-up
- Where
- United States
- Volunteers
- 139 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Medical Abortion
Acceptability and Feasibility of Medical Abortion in Singapore
To test the hypothesis that a regimen of 200 mg oral mifepristone, with the option of home administration, followed by 800 μg buccal misoprostol 24 hours later for abortion through 70 days LMP will be feasible and acceptable in…
- Trial name
- NCT02985229
- Testing
- Mifepristone, Misoprostol
- Where
- 2 sites in Singapore
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- Gynuity Health Projects
Induced Abortion
Expansion Study of a Simplified Regimen of Medical Abortion Thru 63 Last Menstrual Period (LMP) in Tunisia
This open-label study is being conducted to determine whether national expansion of a 400 mcg of sublingual misoprostol (i.e., under the tongue) taken 24 hours following administration of mifepristone 200 mg is effective and…
- Trial name
- NCT01173003
- Testing
- Mifepristone, misoprostol
- Where
- Tunisia
- Volunteers
- 688 people, healthy volunteers welcome
- Sponsor
- Gynuity Health Projects
Medical Abortion
Mifepristone and Two Doses of Misoprostol for Abortion at 11&12 Weeks
This study seeks to evaluate the efficacy, side effect profile and acceptability of a medical abortion regimen with mifepristone and two doses of 800 mcg misoprostol buccally at 71-77 and 78-84 days of gestation to further expand…
- Trial name
- NCT05119439
- Testing
- Mifepristone + 2 doses of misoprostol 800 mcg
- Where
- 6 sites in United States
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- Gynuity Health Projects
Abortion, Therapeutic
Acceptability and Feasibility of a Simplified Medical Abortion Service Delivery in Western Ukraine
The study will examine how a simplified outpatient medical abortion procedure using mifepristone and misoprostol, with the option to take mifepristone at a place of woman's choosing, works in Ukraine.
- Trial name
- NCT02981030
- Testing
- Mifepristone, Misoprostol
- Where
- 2 sites in Ukraine
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- Gynuity Health Projects
Abortion Early
Atorvastatin as a Potential Adjunct to Misoprostol for Termination of Pregnancy
Medication abortion is a way of ending a pregnancy using pills. The current FDA-approved regimen for medication abortion uses mifepristone and misoprostol.
- Trial name
- NCT05342974
- Testing
- Atorvastatin, Misoprostol
- Where
- United States
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- University of Utah
Medical Abortion
Simplifying First Trimester Medical Abortion Follow-up
This study evaluates the usability of the multilevel pregnancy test among women undergoing medical abortion.
- Trial name
- NCT03014193
- Testing
- Semiquantitative Multi-Level Pregnancy Test
- Where
- 5 sites in Armenia, Georgia and 1 more
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Gynuity Health Projects
Abortion, Induced
Oral Mifepristone and Buccal Misoprostol Administered Simultaneously for Abortion Through 63 Days Gestation
HYPOTHESIS: For women with pregnancies at <49, 50-56, and 57-63 days gestation who receive mifepristone 200 mg orally and misoprostol 800 mcg buccally at the same time, the complete abortion rate 24 hours after misoprostol…
- Trial name
- NCT00330993
- Testing
- mifepristone, misoprostol
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Complete Abortion
Mifepristone and Misoprostol for the Termination of Pregnancy up to 70 Days' Gestation in Kazakhstan
The study will be conducted in 4 sites and will examine how a simplified outpatient medical abortion procedure using mifepristone and misoprostol, with the option to take mifepristone at a place of woman's choosing, works in…
- Trial name
- NCT02018796
- Testing
- Mifepristone, misoprostol
- Where
- 4 sites in Kazakhstan
- Volunteers
- 290 people, healthy volunteers welcome
- Sponsor
- Gynuity Health Projects
Abortion
Side Effects and Adherence Associated With Doxycycline Use Following Medical Abortion
The effectiveness of antibiotic treatment at reducing post-abortion infection is unclear. The experiences of women prescribed routine antibiotics after medical abortion is missing from the existing evidence.
- Trial name
- NCT01799252
- Where
- 7 sites in United States
- Volunteers
- 582 people, healthy volunteers welcome
- Sponsor
- Gynuity Health Projects
Abortion, Medical
Chart Review Study of Medical Abortion
The primary objective of this study is to document the rates of success and serious complications among women having outpatient medical abortions with 200 mg mifepristone + 800 buccal misoprostol at 64-70 days of gestation.
- Trial name
- NCT02841072
- Where
- 2 sites in United States
- Volunteers
- 579 people, healthy volunteers welcome
- Sponsor
- Gynuity Health Projects
Abortion, Pregnancy Tests
Simplified Medical Abortion Follow-Up
The purpose of this operations research study is to evaluate women's interest in and compliance with using a semiquantitative multi-level dipstick pregnancy test at home for medical abortion follow-up.
- Trial name
- NCT02524990
- Testing
- Home-based follow-up with SQPT
- Where
- United States
- Volunteers
- 53 people, healthy volunteers welcome
- Sponsor
- Gynuity Health Projects
Miscarriage
Letrozole Pretreatment With Misoprostol for Second-Trimester Medical Abortion
To compare the success rate of letrozole and misoprostol versus misoprostol alone for medical termination of pregnancy in second trimester abortion.
- Trial name
- NCT02405156
- Testing
- Letrozole, Misoprostol
- Where
- Egypt
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Abortion Early, Abortion in First Trimester
Using Telemedicine to Improve Early Medical Abortion at Home
The investigators plan a trial comparing telephone consultations for women requesting early medical abortion (EMA - under 10 weeks pregnant) to regular face-to-face consultations.
- Trial name
- UTAH (NCT04139382)
- Testing
- Telephone Consultation, Face-to-Face Consultation
- Where
- United Kingdom
- Volunteers
- 125 people, healthy volunteers welcome
- Sponsor
- NHS Lothian
Abortion in Second Trimester
Outpatient Service for Mid-trimester Termination of Pregnancy
This study seeks to evaluate the safety, acceptability and feasibility of an outpatient "day procedure" for medical abortion at 13-18 weeks gestation.
- Trial name
- NCT03346629
- Testing
- Mifepristone + Misoprostol
- Where
- 3 sites in Nepal
- Volunteers
- 230 people, healthy volunteers welcome
- Sponsor
- Gynuity Health Projects
Complete Abortion
Comparing Two Regimens for Medical Abortion: Mifepristone + Misoprostol Versus Misoprostol Alone
This double blinded, placebo-controlled randomized trial will compare the safety, efficacy and acceptability of two medical abortion regimens up to 63 days since last Menstrual Period (LMP) in Tunisia and Vietnam.
- Trial name
- NCT01387256
- Testing
- medical abortion
- Where
- 2 sites in Tunisia, Vietnam
- Volunteers
- 441 people, healthy volunteers welcome
- Sponsor
- Gynuity Health Projects
Induced Abortion
Study of Sublingual Versus Oral Misoprostol Administration Following Mifepristone 200 mg for Abortion up to 63 Days Gestation
This open-label, randomized study is being conducted to determine whether a dose of 400 mcg of sublingual misoprostol (i.e., under the tongue) taken 24 hours following administration of mifepristone 200 mg is effective and…
- Trial name
- NCT00286208
- Testing
- Mifepristone, misoprostol
- Where
- 9 sites in Moldova, Tunisia and 1 more
- Volunteers
- 1,443 people, healthy volunteers welcome
- Sponsor
- Gynuity Health Projects