Clinical trials: Abortion, Recurrent
Recurrent Miscarriages, Habitual Abortions
Description of the Uterine Cavity in Patients With Recurrent Miscarriages
To be diagnosed with recurrent miscarriages, a couple might have a child, however experiences three or more miscarriages, primarily this happens during the first trimester.
- Trial name
- NCT02746588
- Testing
- Office hysteroscopy
- Where
- Denmark
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Hvidovre University Hospital
Polycystic Ovary Syndrome
Changes in Pregnancy in Egyptian Women With History of Recurrent Miscarriage
Introduction: Elevated levels of androgen and insulin-resistant have been implicated in recurrent miscarriage in women with PCOS.
- Trial name
- NCT04960982
- Testing
- blood test
- Where
- Egypt
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Kafrelsheikh University
Recurrent Miscarriage
The Role of Prothrombin Gene and Methylenetetrahydrofolate Reductase(MTHFR) Gene Polymorphisms as Risk Factors for Recurrent Miscarriage
Recurrent miscarriage is a pregnancy loss before 20 weeks of gestation. The recurrent pregnancy loss(RPL) usually occurring in the first trimester of gestation and its rate is quite high (15-20% even in full reproductive period)…
- Trial name
- NCT03209063
- Testing
- polymerase chain reaction
- Volunteers
- 285 people, healthy volunteers welcome
- Sponsor
- Assiut University
Recurrent Pregnancy Loss, Not Pregnant, Vaginal Microbiome
Uterine Microbiome in Recurrent Pregnancy Loss
The female genital tract microbiome may reflect female reproductive health and may be related to pregnancy outcomes. Disturbances in this microbiome may be associated with adverse reproductive outcomes.
- Trial name
- NCT05510622
- Testing
- Vaginal swab and endometrial biopsy
- Where
- 2 sites in Vietnam
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Mỹ Đức Hospital
Cervical Insufficiency
Patient Attitudes Toward Ultrasound Measurement of Cervical Length
The investigators propose a prospective evaluation of methods to assess cervical length for uncomplicated singleton gestations between 18-28 weeks presenting to the MFM office for routine mid pregnancy ultrasound.
- Trial name
- TVUS (NCT01482039)
- Testing
- Sequential ultrasound, Transvaginal ultrasound
- Where
- United States
- Volunteers
- 210 people, healthy volunteers welcome
- Sponsor
- Intermountain Women and Children's Research
Recurrent Pregnancy Loss
Genomic Predictors of Recurrent Pregnancy Loss
The overall goals of this proposal are to determine the genetic architecture of recurrent pregnancy loss (RPL) and to discover genomic predictors of RPL.
- Trial name
- GPRPL (NCT05444283)
- Where
- 10 sites in United States
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Yale University
Infertility, Recurrent Pregnancy Loss
TNFα and MFG-E8: Novel Biomarkers to Predict Implantation Failure
Question: Can implantation failure (IF) be predicted prior to in vitro fertilization (IVF)? A pilot, non-interventional, clinical study Prospective, controlled, cohort study
- Trial name
- NCT02386384
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Eastern Virginia Medical School
Recurrent Pregnancy Loss
Effectiveness of Aspirin in Compare With Heparin Plus Aspirin in Recurrent Pregnancy Loss Treatment
This study evaluated the effect of anticoagulant treatment on the live-birth rate in women with a history of at least two continuous unexplained miscarriages or thrombophilia.
- Trial name
- NCT01542411
- Where
- Iran
- Volunteers
- 520 people, healthy volunteers welcome
- Sponsor
- Yazd Medical University
Induced Abortion
Post Abortion IUD & Recurrent Abortion 2005-2006
The rate of repeat abortions will be lowest in those women who choose immediate insertion of an IUD post-abortion versus those who immediately choose oral contraceptive pills and those who indicate all other contraceptive choices…
- Trial name
- NCT01776957
- Testing
- Device: Intrauterine device (IUD)
- Volunteers
- 1,308 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Recurrent Pregnancy Loss(RPL), Recurrent Miscarriage
Low Dose Prednisone Therapy in Women With Recurrent Pregnancy Loss
For many years there is a lack of large randomized controlled trials that study the effect of low dose prednisone in women with RPL and thus the evidence of a probable efficacy of prednisone in RPL women remains limited and…
- Trial name
- NCT04558268
- Testing
- Prednisone, Progesterone, vit D
- Where
- Israel
- Volunteers
- 242 people, healthy volunteers welcome
- Sponsor
- Soroka University Medical Center
Recurrent Pregnancy Loss, Endoplasmic Reticulum Stress
Evaluation of Endoplasmic Reticulum Stress in Patients With Recurrent Pregnancy Loss
To evaluate endoplasmic reticulum stress in women with recurrent pregnancy loss and those who had healthy births in the same age group. The level of the unfolded protein X box binding protein 1 (XBP-1) is measured.
- Trial name
- NCT04455256
- Testing
- x box binding protein
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Kanuni Sultan Suleyman Training and Research Hospital
Infertility, Abnormal Uterine and Vaginal Bleeding, Unspecified
Optimum Misoprostol Dose Prior to Office Hysteroscopy
Misoprostol is an effective agent for cervical priming before office hysteroscopy, vaginal route is the best, optimum dose not yet known.
- Conditions
- Infertility, Abnormal Uterine and Vaginal Bleeding, Unspecified, Recurrent Abortion
- Trial name
- NCT01612065
- Testing
- Misoprostol
- Where
- Egypt
- Volunteers
- 132 people, healthy volunteers welcome
- Sponsor
- Cairo University
Insulin Resistance
Insulin Resistance in Recurrent Miscarriage
The objective of this study is to study the association between insulin resistance and recurrent spontaneous miscarriage (RSM).
- Trial name
- IRRM (NCT02705248)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Ain Shams Maternity Hospital
Miscarriage
Mucosal-Associated Invariant T Cells in Cases of Miscarriage
Miscarriage is the most frequently encountered complication of pregnancy ranging from 10% to 30%. The etiology of recurrent spontaneous miscarriage (RSM) in 40%-50% of cases cannot be identified.
- Trial name
- NCT04492098
- Testing
- MAIT cells
- Where
- Egypt
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Assiut University
Abortion in First Trimester
Progesterone and Doppler in Recurrent Abortion
Recurrent pregnancy loss is classically defined as the occurrence of three or more consecutive pregnancy loss. The American Society of Reproductive Medicine has recently redefined recurrent pregnancy loss as two or more pregnancy…
- Trial name
- NCT03267771
- Testing
- Progesterone Suppositories Vaginal, Dydrogesterone Oral Tablet, doppler ultrasound
- Where
- Egypt
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Assiut University
Preterm Birth
Preventing Preterm Birth With a Pessary
The primary objective of this study, is to determine the effect of a Cup pessary, a device that is currently readily available in the USA and similar in design to the Arabin pessary, on the incidence of delivery prior to 37 weeks…
- Trial name
- PrePPy (NCT01380158)
- Testing
- Cup pessary (Bioteque America, Inc)
- Where
- 3 sites in United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Medstar Health Research Institute
Obese, Overweight
Efficacy of a Structured Weight Loss Program in Overweight Women With a History of Recurrent Pregnancy Loss
Overweight and obesity has been associated with a number of adverse pregnancy outcomes in women of reproductive age, including infertility and early pregnancy loss.
- Conditions
- Obese, Overweight, Miscarriage, Recurrent Pregnancy Loss
- Trial name
- NCT01325805
- Testing
- Structured Weight Loss Program, Routine Weight Loss Counseling
- Where
- United States
- Volunteers
- 7 people, healthy volunteers welcome
- Sponsor
- Stanford University
Abortion Rate
Post Abortion IUD & Recurrent Abortion 2001-2004
It has been shown that the immediate insertion of intrauterine devices (IUDs) post-abortion prevents repeat abortions. The researchers hypothesize that providing free IUDs post-abortion will be associated with a lower rate of…
- Trial name
- NCT00965770
- Testing
- Intrauterine device (IUD)
- Where
- Canada
- Volunteers
- 1,101 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Obesity, Inflammation
Inflammasome Activation and Cortisol Metabolism in Obese Women With Recurrent Miscarriage
The prevalence of obesity among women of reproductive age is increasing. Obesity represents a chronic low-grade inflammatory state and NLRP3 inflammasome plays a pivotal role in obesity-induced inflammation.
- Trial name
- NCT04275674
- Where
- Taiwan
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- National Cheng-Kung University Hospital
Abortion, Spontaneous
Interleukin-10 Promoter-1082A/G Polymorphism and Idiopathic Recurrent Miscarriage Risk
This study aimed to assess the correlation between the interleukin-10 (IL-10)-1082A/G polymorphism and idiopathic recurrent miscarriage (IRM) of Chinese Han.
- Trial name
- NCT02633475
- Testing
- IL-10 polymorphism
- Where
- 2 sites in China
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Fourth Affiliated Hospital of Guangxi Medical University